微创手术治疗腰椎间盘突出症患者的疗效及对血IL-6、CK、CRP的影响

Abstract objective To investigate the effect of minimally invasive surgery on patients with lumbar disc herniation and analyze the effect of IL-6, CK and CRP

目的 :探讨微创手术对腰椎间盘突出症患者的治疗效果,分析IL-6、CK、CRP对疗效的影响。方法 :选取124名腰椎间盘突出症患者,根据手术方式不同随机分为观察组、对照组,每组62例患者。比较两组患者术后出血量、手术时间、VAS评分以及住院时间等手术指标;在术前、术后24h,术后48h检测患者IL-6、CK、CRP表达水平;比较患者术后并发症发生率。结果 :微创手术组患者术后出血量、手术时间、VAS评分、住院时间均低于对照组;观察组患者术前、术后24h,术后48h的IL-6、CK、CRP水平低于对照组;观察组和对照组的出现神经根损伤的有1例和8例,术后大出血发生人数分别为2例和9例,观察组患者术后并发症的发生率显著低于对照组。结论:微创手术治疗腰椎间盘突出症能有效减少炎症因子的释放及手术创伤,手术疗效好,能有效减轻患者手术痛苦,提高患者的生活质量。

Objective To investigate the effect of minimally invasive surgery on patients with lumbar disc herniation and analyze the effect of IL-6, CK and CRP. Method 124 patients with lumbar disc herniation were selected, and randomly divided into observation group and control group according to different surgical methods. Each group included 62 patients. The operative indexes such as postoperative bleeding volume, operation time, VAS score and hospitalization time were analyzed and compared. The levels of IL-6, CK and CRP were measured before operation, 24 hours after operation and 48 hours after operation. Compare the postoperative complications. Result The loss of blood, operation time, VAS score and hospital stay of patients in minimally invasive surgery group were significantly lower than those in control group. The levels of IL-6, CK and CRP in the observation group before operation, 24 h after operation and 48 h after operation were lower than those in the control group. There were 1 case and 8 cases of nerve root injury in the observation group and the control group. The number of postoperative hemorrhage occurred in 2 cases and 9 cases respectively. The complication occurred in the observation group, the rate was significantly lower than the control group. Conclusion Minimally invasive surgery for the treatment of lumbar disc herniation can effectively reduce the release of inflammatory cytokines and surgical trauma, surgery is effective, can effectively reduce the pain of patients with surgery and improve the quality of life of patients.