期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

ⅠB期非小细胞肺癌术后辅助化疗临床疗效观察

下载PDF
导出
摘要 目的:分析ⅠB期非小细胞肺癌完全切除术后辅助化疗的临床价值.方法:2009年10月～2011年3月收治的67例ⅠB期非小细胞肺癌完全切除术后患者,按是否接受辅助化疗,分为辅助化疗组和非辅助化疗组.辅助化疗组化疗4～6个周期,并同时积极处理化疗毒副反应.全部患者随访并采用Kaplan-Meier法分析两组患者第1、第2、第3年生存率.结果:辅助化疗组和非辅助化疗组1年生存率分别为94.12％(32/34例)和93.94％(31/33例),2年生存率分别为93.94％(31/34例)和87.89％(29/33例),3年生存率分别为88.24％(30/34例)和84.85％(28/33例)(x2=7.22,P=0.027),辅助化疗组的长期生存率高于非辅助化疗,差异有统计学意义.结论:对于ⅠB期非小细胞肺癌完全切除术后患者,积极进行辅助化疗,可以提高疗效.
作者 卞保祥 宋子琰 郑义同 吴风雷
机构地区 江苏省徐州医学院附属连云港医院 江苏徐州
出处 《临床心身疾病杂志》 CAS 2016年第S1期66-67,共2页 Journal of Clinical Psychosomatic Diseases
基金 江苏省“六大人才高峰”项目
关键词 ⅠB期非小细胞肺癌 辅助化疗 疗效
分类号 R734.2 [医药卫生—肿瘤]
  • 相关文献

参考文献2

二级参考文献60

  • 1Ou SH, Zell JA, Ziogas A, et al. Prognostic factors for survival of stage I non- small cell lung cancer patients: a population-based analysis of 19,702 stage I patients in the California Cancer Registry from 1989 to 2003. Cancer, 2007, 110(7): 1532-1541.
  • 2Raz DJ, Zell JA, Ou SH, et al. Natural history of stage I non-small cell lung cancer: implications for early detection. Chest, 2007, 132(1): 193-199.
  • 3Groome PA, Bolejack V, Crowley JJ, et al. The IASLC Lung Cancer Staging Project: validation of the proposals for revision of the T, N, and M descriptors and consequent stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumors. J Thorac Oncol, 2007, 2(8): 694-705.
  • 4Goldstraw P, Crowley J, Chansky K, et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours.J Thorac Oncol, 2007, 2(8): 706-714.
  • 5Boffa DJ, Allen MS, Grab JD, et al. Data from The Society of Thoracic Surgeons General Thoracic Surgery database: the surgical management of primary lung tumors.J Thorac Cardiovasc Surg, 2008, 135(2): 247-254.
  • 6Scott wJ, Howington J, Feigenberg S, et al. Treatment of non-small cell lung cancer stage I and stage II: ACCP evidence-based clinical practice guidelines (2nd edition). Chest, 2007, 132(3 Suppl): 234S-242S.
  • 7Sienel W, Dango S, Kirschbaum A, et al. Sublobar resections in stage IA non- small cell lung cancer: segmentectomies result in significantly better cancerrelated survival than wedge resections. EurJ Cardiothorac Surg, 2008, 33(4): 728-734.
  • 8Sienel W, Stremmel C, Kirschbaum A, et al. Frequency of local recurrence following segmentectomy of stage IA non-small cell lung cancer is influenced by segment localisation and width of resection margins-implications for patient selection for segmentectomy. Eur J Cardiothorac Surg, 2007, 31(3): 522-528.
  • 9Darling GE, Allen MS, Decker PA, et al. Number of lymph nodes harvested from a mediastinal lymphadenectomy: results of the randomized, prospective American College of Surgeons Oncology Group Z0030 trial. Chest, 2011, 139(5): 1124-1129.
  • 10Allen MS, Darling GE, Pechet TT, et al. Morbidity and mortality of major pulmonary resections in patients with early-stage lung cancer: initial results of the randomized, prospective ACOSOG Z0030 trial. Ann Thorac Surg, 2006, 81(3): 1013-1020.

共引文献8

临床心身疾病杂志
2016年 第S1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部