急性冠状动脉综合征合并2型糖尿病患者不良心血管事件临床分析

Clinical analysis of adverse cardiovascular events in patients with acute coronary syndrome complicated with type 2 diabetes mellitus

目的 探讨急性冠状动脉综合征合并2型糖尿病患者不良心血管事件发生率及预后危险因素.方法 将412例急性冠状动脉综合征患者根据是否合并2型糖尿病分为观察组123例与对照组289例.收集患者的一般资料,术后随访36个月统计两组不良心血管事件发生率,分析预后危险因素.结果 观察组再次血运重建、心绞痛、心源性休克及不良心血管事件总发生率显著高于对照组(P＜0.05或0.01),心源性死亡及再发心肌梗死发生率比较差异无统计学意义(P＞0.05).年龄、空腹血糖及血脂异常是急性冠状动脉综合征患者不良心血管事件的重要预后危险因素(P＜0.05).结论 急性冠状动脉综合征合并2型糖尿病患者不良心血管事件发生率较高,而年龄、血脂异常、空腹血糖是不良心血管事件的重要危险预测因素.

Objective To investigate the incidence of adverse cardiovascular events and prognostic risk factors in patients with acute coronary syndrome and type 2 diabetes mellitus. Method 412 cases of patients with ACS were divided into the observation group (n = 123) and the control group (n = 289) according to whether they had T2DM or not. General data of patients were collected, the incidences of adverse cardiovascular events of the two groups within 36 months after operation were followed up, and prognostic risk factors were analyzed. Results Total incidence of TLR,angina, CGS and adverse cardiovascular events of the observation group was significantly higher than that of the control group (P＜0.05 or 0.01),there was no statistic significance between the incidence of cardiac death and recurrent myocardial infarction(P＞0.05). Age, FBG and dyslipidemia were important risk factors for adverse cardiovascular events in patients with ACS (P＜0.05). Conclusion The incidence of adverse cardiovascular events in ACS patients with T2DM is high, while age, dyslipidemia and fasting blood glucose are important risk factors for adverse cardiovascular events.