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新辅助介入化疗对中晚期宫颈癌患者预后的影响 被引量:3

Influence of new adjuvant interventional chemotherapy on the prognosis of advanced cervical cancer patients
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摘要 目的 探讨新辅助介入化疗对中晚期宫颈癌患者预后的影响.方法 将76例中晚期宫颈癌患者根据治疗方法分为介入化疗组(32例)与全身化疗组(44例),比较两组近期、远期疗效及不良反应发生率.结果 介入化疗组近期疗效显著优于全身化疗组(P<0.01),平均生存时间显著长于全身化疗组(P<0.01).两组不良反应发生率及远期疗效比较差异无统计学意义(P>0.05).结论 新辅助介入化疗治疗中晚期宫颈癌近期疗效较好,可以有效延长患者的平均生存时间,但3 a生存率无明显改善,临床需结合患者实际情况选择最佳的治疗方案. Objective To investigate the influence of new adjuvant interventional chemotherapy on the prognosis of advanced cervical cancer patients. Methods 76 cases of advanced cervical cancer patients were divided into interventional chemotherapy group (32 cases) and systemic chemotherapy group (44 cases), compare the short-term and long-term curative effect, adverse reaction rate of the two groups. Results The short-term effect of the interventional chemotherapy group was significantly better than that of the systemic chemotherapy group (P<0.01),average survival time was significantly longer than that of the systemic chemotherapy group (P<0.01). There was no statistic significance in the adverse reaction rate and long-term curative effect between the two groups (P>0.05). Conclusion New adjuvant interventional therapy has better clinical effect in advanced cervical cancer patients, it can effectively prolong the average survival time, but it has no significant improvement on the 3-year survival rate, it needs to be further studied and improved to adjust to the patients' condition.
出处 《临床心身疾病杂志》 CAS 2018年第4期146-147,共2页 Journal of Clinical Psychosomatic Diseases
基金 河南省卫计委医学科技攻关项目(编号2011020145)
关键词 中晚期宫颈癌 新辅助介入化疗 近期疗效 远期疗效 不良反应 Advanced cervical cancer new adjuvant interventional therapy short-term effect long-term effect adverse reaction
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