胶原酶溶解术联合胶原酶＋臭氧注射治疗腰椎间盘突出症疗效观察

Curative effect observation of collagenase dissolution combined with collagenase ＋ ozone injection in the treatment of lumbar disc herniation

目的 探讨胶原酶溶解术联合胶原酶十臭氧注射治疗腰椎间盘突出症的临床疗效.方法 将130例腰椎间盘突出症患者采用随机数字表法分为两组,每组65例.两组均给予胶原酶溶解术治疗,观察组联合胶原酶十臭氧注射治疗,比较两组治疗后及随访期间临床疗效及不良反应发生率.结果 治疗后及随访1个月、3个月6个月观察组临床疗效均显著优于对照组(P＜0.05或0.01),两组不良反应发生率比较差异无统计学意义(P＞0.05).结论 胶原酶溶解术联合胶原酶十臭氧注射治疗腰椎间盘突出症效果显著,安全可靠,值得在临床上推广应用.

Objective To observe the clinical effect of collagenase dissolution combined with collagenase + ozone injection in the treatment of lumbar disc herniation. Methods 130 cases of lumbar disc herniation were randomly divided into control group and observation group, 65 cases in each group. The two groups were all given collagenase dissolution treatment, the observation group was given collagenase + ozone injection, compare the clinical effect and adverse reaction rate of the two groups after treatment and during the follow up period. Results The clinical effect of the observation group was significantly better than that of the control group after treatment and 1,3,6 months' follow up (P＜0.05 or 0.01),there was no statistic significance in the adverse reaction rate between the two groups (P＞0.05). Conclusion Collagenase dissolution combined with collagenase + ozone injection in the treatment of lumbar disc herniation has significant effect, it is safe and reliable, and it is worthy of promotion and application in clinic.