依托咪酯复合小剂量舒芬太尼对老年喉罩置入患者呼吸循环功能的影响

Effects of etomidate combined with low dose sufentanil on respiratory and circulatory function in elderly patients with laryngeal mask

目的 探讨依托咪酯复合小剂量舒芬太尼对老年喉罩植入患者呼吸循环功能的影响.方法 将47例需要进行喉罩置入麻醉手术的老年患者采用随机数字表法分为两组,两组均给予依托咪酯与咪达唑仑进行麻醉,研究组在此基础上给予小剂量舒芬太尼,比较两组患者麻醉前后呼吸循环系统功能各项指标的水平变化及不良反应发生情况.结果 置入后3min、拔出前即刻研究组呼气末二氧化碳及气道压力水平显著低于对照组(P＜0.05或0.01).置入后各时点研究组平均动脉压及心率显著低于对照组(P＜0.01).研究组不良反应发生率为16.7％,对照组为47.8％,研究组显著低于对照组(P＜0.01).结论 依托咪酯复合小剂量舒芬太尼对老年喉罩置入患者的呼吸循环系统影响较小,不良反应发生率较低,值得推广应用.

Objective To observe the clinical effect of etomidate combined with low dose sufentanil on respiratory and circulatory function in elderly patients with laryngeal mask. Methods 47 elderly patients underwent laryngeal mask insertion anesthesia were randomized divided into two groups, they were all given etomidate and midazolam, the observation group was given low dose sufentanil on this basis, the index level changes of respiratory and circulatory function and the occurrence of adverse reactions of the two groups were compared. Results The PETCO2 and PAW levels in the observation group at 3 min after implantation and immediately before removal were significantly lower than those in the control group (P＜0.05 or 0.01). The MAP and HR levels in the observation group at each time points after implantation were significantly lower than those in the control group (P＜0.01). The adverse reaction rate of the observation group (16.7％) was significantly lower than that of the control group (47.8％) (P＜0.01). Conclusion The combination of etomidate and low dose sufentanil have less influence on the respiratory and circulatory function in elderly patients with laryngeal mask, with lower adverse reaction rate, it is worthy of wide application.