综合护理干预对糖尿病足溃疡面修复相关因子的影响探析

Influence of Comprehensive Nursing Intervention on Related Factors of Diabetic Foot Ulcer Surface Repair

目的观察综合护理干预对糖尿病足溃疡面修复相关因子的影响。方法选取该院2014年10月—2017年10月收治的42例糖尿病足溃疡患者均分为观察组和对照组。观察组实施综合护理干预,对照组实施常规护理干预,对比两组临床相关指标、护理前后溃疡面修复相关因子表达量的差异。结果观察组和对照组换药次数、换药时间、创面愈合时间比较,前者明显短于后者(P<0.05)。护理后,两组b FGF、EGF、VEGF、PDGF、AEGs表达量对比,差异有统计学意义(P<0.05)。结论综合护理干预应用于糖尿病足溃疡面修复中,能够减少患者换药次数和时间,促进溃疡面修复因子b FGF、EGF、VEGF、PDGF表达,防止负性因子AEGs生成,创面可及早愈合。

Objective To observe the effect of comprehensive nursing intervention on the related factors of diabetic foot ulcer surface repair. Methods 42 patients with diabetic foot ulcers admitted in our hospital from October 2014 to October 2017 were divided into observation group and control group equally. The observation group implemented the comprehensive nursing intervention, the control group carried out routine nursing intervention, compared the two groups of clinical related indicators and the difference in the expression of the ulcer surface repair related factors before and after nursing. Results The number of dressing change, dressing change time and wound healing time in the observation group and the control group were significantly shorter than those in the latter group(P<0.05). After nursing, the expression of b FGF, EGF, VEGF, PDGF and AEGs in the two groups was statistically significant(P<0.05). Conclusion The application of comprehensive nursing intervention to the repair of diabetic foot ulcer surface can reduce the times and times of change, promote the expression of b FGF, EGF, VEGF and PDGF of the repair factor of the ulcer surface, prevent the formation of negative factor AEGs, and the wound can be healed early.