肌电图诊断先天性巨结肠症的评价

Clinical Evaluation of Anorectal Electromyography in Diagnosis of Hirschsprung's Disease

先天性巨结肠症(HD)的辅助诊断方法除X线检查和直肠活组织检查外,近年来相继开展了肛门直肠测压检查,直肠粘膜乙酰魈碱酯酶组织化学(简称组化)检查,红细胞乙酰胆碱酯酶活性测定,以及直肠肛管肌电图(简称肌电图)检查.

Electromyographic activity of the colon was studied in 41 patients suffering from aganglionic megacolon and in 29 normal infants and children by an intraluminal electrode.Graphs obtained in the control children showed a basic electrical rhythm with bursts of high frequency spikes,but the recording in Hirschsprung's disease showed only a basic electrical rhythm without high frequency potentials when the electrode is placed in the aganglionic zone.On the basis of the disappearance of the bursts of high frequency spikes,the diagnostic rate of Hirschsprung's disease by anorectal eletromyography(AEMG) was 78.1%.Based on pathological changes showed by barium enema,the accuracy of electromyography,in revealing the extent of the 1esion was 84%.These findings suggest that electromyography can be very helpful in the diagnosis of Hirschsprung's disease.