苦参黄芪注射液联合顺铂胸腔内注射治疗肺癌胸水疗效观察

Sophora radix astragali injection combined cisplatin intrathoracic injection clinical observation on treatment of lung cancer hydrothorax

目的：探讨肺癌合并癌性胸水患者采用苦参黄芪注射液联合顺铂进行胸腔内注射治疗的临床效果。方法选取我院年近2年收治的肺癌合并癌性胸水患者共70例为研究对象，随机分为观察组和对照组，每组各35例。两组患者均进行胸腔穿刺置管引流胸水后注射顺铂，观察组额外加用苦参黄芪注射液进行治疗，治疗1个月后对比两组临床疗效同时收集不良反应发生情况。结果观察组在临床治疗总有效率方面显著优于对照组（P＜0.05）。结论苦参黄芪注射液联合顺铂治疗非小细胞肺癌胸水，能够有效提高化疗药的疗效，一定程度上减轻化疗药物反应，值得临床应用。

Objective To study the patients with lung cancer hydrothorax merger with bitter and astragalus injection combined cisplatin intrathoracic injection clinical effect of treatment.Methods Selected nearly 2 years treated in our hospital,a total of 70 patients with lung cancer merger cancerous hydrothorax as the research object,were randomly divided into observation group and control group,each group of 35 cases. Two groups of patients with chest drainage tube after the chest after water injection of cisplatin,observation group with an extra sophora radix astragali injection treatment,1 month after treatment compared two groups of clinical curative effect and other adverse reactions occur.Results The observation group in the clinical total effective rate significantly better than that in control group (P<0.05).Conclusion The sophora radix astragali injection combined cisplatin in the treatment of non-small cell lung cancer with pleural effusion,can effectively improve the curative effect of effective,to some extent alleviate chemotherapy drug reaction,worthy of clinical application.