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高危型HPV检测联合TCT在宫颈癌筛查中的应用 被引量:1

Application of high risk type HPV detection combined with TCT in the screening of cervical cancer
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摘要 目的:总结分析高危型HPV(人乳头状瘤病毒)与TCT(液基薄层细胞学检查)在筛查宫颈癌中的应用价值。方法选择2012年10月~2015年10月期间我院收治的228例有病理检查结果的宫颈癌筛查患者为研究对象,均进行了高危型HPV检测及TCT检查,并以病理检查为标准诊断结果(HSIL和宫颈癌判为阳性),比较HPV检测与TCT检测筛查宫颈癌的准确率、特异性、灵敏性及阳性预测值和阴性预测值。结果联合检测组的诊断准确率82.02%、特异性86.69%以及阴性预测值98.65%,明显高于HPV检测组及TCT检测组,且差异具有统计学意义(P<0.05)。结论 HPV检测宫颈癌的灵敏性高,但特异性、准确性低,TCT检查宫颈癌灵敏性低,但是特异性及准确性高,二者联合应用可以优势互补,提高筛查效果。 Objective To summarize and analyze the application value of high risk type HPV (human papilloma virus) and TCT (liquid based cytology test) in screening of cervical cancer. Methods Choose 2012 October 2015 in October period in our hospital treated 228 cases with pathological examination results of cervical cancer screening patients as the research object, high-risk HPV test and TCT examination, and the pathology as the standard diagnosis results (HSIL and cervical cancer found positive), than the accuracy of TCT and HPV detection detection in the screening of cervical cancer, specificity, sensitivity and positive predictive value and negative predictive value. Results The diagnostic accuracy rate of combined detection group was 82.02%, specificity 86.69%and negative predictive value 98.65%, which was significantly higher than that of HPV group and TCT group, and the difference was statistically significant (P<0.05). Conclusion HPV detection in cervical cancer with high sensitivity, but specificity, low accuracy and sensitivity of TCT screening for cervical cancer in low, but the specificity and accuracy, the combination of the two can complementary advantages, enhance the effect of screening.
作者 于喜法
机构地区 [
出处 《临床研究》 2016年第9期7-8,共2页 Clinical Research
关键词 高危型HPV检测 TCT检查 宫颈癌 high risk HPV detection TCT examination cervical cancer
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