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慢性阻塞性肺病患者血清YKL-40的表达研究

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摘要 目的:探讨血清甲壳质酶蛋白40(YKL-40)水平与慢性阻塞性肺病(chronic obstructive pulmonary disease,COPD)的相关性及意义。方法选取2013年10月-2015年4月我院收治的60例COPD患者,同时纳入60例门诊健康查体成人做为对照组,用ELISA法测定其YKL-40水平。结果 COPD患者血清YKL-40水平高于对照组,差异具有统计学意义(P<0.05);治疗后,COPD患者肺功能显著提高(P<0.05),血清YKL-40水平较治疗前降低,差异具有统计学意义(P<0.05)。结论血清YKL-40可能作为评价COPD诊断与治疗新的标记物。
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出处 《临床研究》 2016年第10期213-214,共2页 Clinical Research
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