新疆乌鲁木齐市维吾尔族 COPD 患者肺功能与年龄、体重指数的相关性研究

The research on the relevance between lung function,age and body mass index in Uighur patients with COPD in Urumqi,Xinjiang

目的：分析维吾尔族 COPD 患者肺功能与年龄、体重指数之间的相关性。方法纳入2012年2月~2014年2月在我院门诊及住院的维吾尔族 COPD 患者458例，对患者的一般情况（性别、年龄、身高、体重），体重指数（BMI）以及肺功能情况进行调查，分析维吾尔族 COPD 患者性别、年龄分布特点及肺功能与年龄、BMI 之间的相关性。结果维吾尔族COPD 患者肺功能以Ⅱ级为最多（P<0.05），所有 COPD 患者的平均体重均超重（BMI≥24），而 COPD Ⅳ级的患者 BMI 显著低于其他3组（P<0.05）。按照体重指数分层，中低体重指数患者的 FEV1、FVC 及 PEF 均显著低于正常体重指数和高体重指数患者，而高体重指数患者 PEF 值高于正常体重指数组（P<0.05）。维吾尔族 COPD 患者 FEV1和 PEF 与年龄呈显著负相关（P<0.01），与 BMI 呈显著正相关（P<0.05）。结论新疆维吾尔族 COPD 患者具有体重指数高、体型偏胖的特点，且 FEV1和 PEF 与年龄呈负相关，与 BMI 呈正相关。

Objective To analyse the correlation between pulmonary function,age and body mass index. Methods Collected 458 Uighur COPD patients from Feb 2012 to Feb 2014 in our hospital. Investigated the patients' general condition (gender, age, height, weight), body mass index(BMI) and the lung function results. Analysed the characteristics of the Uighur COPD patients' gender, age distribution and the correlation between age, BMI and lung function. Results The severity ex-tend of most Uighur patients with COPD was in class Ⅱ(P<0.05), the average weight index of all the patients with COPD reached the standard of overweight (BMI≥24), and BMI of COPD in class Ⅳ patients was significantly lower than the other three groups (P<0.05). Stratified by body mass mdex,the FEV1, FVC and PEF of Uighur patients with low body mass index were signifi-cantly lower than patients with normal body mass index and higher body mass index, and PEF value of higher body mass index was higher than that of patients with normal body mass index(P<0.05). FEV1 and PEF had significantly negative correlation with age in Uighur patients with COPD(P<0.01),and significantly positive correlation with the BMI(P<0.05). Conclusion Uighur COPD patients have a higher body mass index. FEV1 and PEF have negative correlation with age, and positive correlation with BMI.