流行性出血热患者血液流变学改变的初步观察

PRELIMINARY OBSERVATION ON THE CHANGES OF BLOOD RHEOLOGY IN EPIDEMIC HEMORRHAGIC FEVER

本文报告流行性出血热(EHF)患者105例血液流变学及甲皱微循环观察结果,表明EHF在病程早期血液浓稠性增高,全病程血液粘滞性增加,并有血细胞聚集性增强,晚期血液凝固性有所增加.提示血液粘度的异常可能是EHF微循环障碍的重要因素之一.动态观察血液流变学及甲皱微循环似可作为判断EHF的病情和预后指标之一,并有助于指导治疗.

This paper reports the results of observation on the blood rheology and nail fold microcirculation in 105 cases with epidemic hemorrhagic fever(EHF).It showed that there were increase of blood concentration in the early period,increase of blood viscosity and blood cell aggregation through the whole course and increase of blood Coagulation in the late period.The results suggest that the abnormality of blood viscosity might be an important factor of dysmicrocirculation in EHF.Observing blood theology and nail fold miorocirculation dynamically might provide an index for evaluating the severity and anticipating the prognosis of the disease and for the referance of treatment.