儿童阻塞性睡眠呼吸暂停低通气综合征生活质量和焦虑抑郁情绪症状的分析

Analysis on quality of life and emotion symptoms in children with obstructive sleep apnea-hypopnea syndrome

目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)对儿童生活质量和焦虑抑郁情绪症状的影响。方法对OSAHS患儿进行生活质量、焦虑和抑郁情绪症状调查。病例组选取青少年OSAHS患者120例,选择同期健康青少年100名作为对照组。以儿童阻塞性睡眠呼吸暂停疾病特异性生活质量调查表(OSA-18)、儿童焦虑相关情绪筛查量表(SCARED)、儿童抑郁症状障碍评价量表(CDI)对研究对象进行评估,比较OSAHS组患儿与对照组儿童各维度得分的差异。以SPSS 16.0统计软件进行结果分析。结果 OSAHS患儿生活质量各维度(睡眠障碍、身体症状、情绪症状、白天功能、监护人关心的问题)的评分均值均明显高于健康对照组,差异有统计学意义(P均<0.001)。OSAHS患儿组SCARED、CDI症状得分分别为(25.23±3.36)分和(21.36±2.33)分,显著高于对照组的(18.22±1.26)分及(17.21±0.98)分,差异有统计学意义(t=19.74,P<0.001;t=16.62,P<0.001)。OSAHS患儿焦虑抑郁情绪症状主要相关的生活质量维度包括睡眠障碍、身体症状和监护人关心的问题,P均<0.001。结论 OSAHS影响儿童生活质量、焦虑抑郁情绪症状,采取适当的临床处理,可明显提高患儿的生活质量,并改善其焦虑抑郁情绪症状,有利于OSAHS患儿的身心健康发展。

Objective To explore the quality of life (QOL) and emotion symptoms (anxiety symptom and depressive symptom) of children with OSAHS.Methods A case-control study on quality of life and emotion symptoms among 120 OSAHS children and 100 controls was performed. The participants were investigated by questionnaires of OSA-18, ICD, and SCARED. SPSS 16.0 software was used to analyze the data.Results The scores of OSA-18 five dimensions with OSAHS were higher than the controlled subjects respectively (all P<0.001). The scores of SCARED (25.23±3.36) scoresvs. (18.22±1.26) scores and ICD (21.36±2.33) scoresvs. (17.21±0.98) scores in SDB was higher than the controlled subjects (t=19.74,P<0.001;t=16.62,P<0.001). Furthermore, anxiety and depression symptom were significantly associated with sleep disturbance, physical symptoms and caregiver concerns. Conclusions The quality of life and emotion symptoms were significantly affected by OSAHS. It is important to pay attention to overall health in OSAHS children.