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罗格列酮对肾小管间质纤维化模型大鼠的保护作用及其相关机制 被引量:4

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摘要 肾小管-间质纤维化(TIF)是各种慢性肾脏病(CKD)进展到终末期肾病的共同病理特征,其严重程度与肾功能减退及CKD预后密切相关,目前临床仍缺乏有效的干预防治措施.脂肪组织分泌的细胞因子脂联素(adiponectin)在肾脏中具有抑制炎性反应及氧化应激、改善血管内皮细胞功能和抗纤维化等作用,可能成为防治CKD的干预靶点[1]. @@
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出处 《中华肾脏病杂志》 CSCD 北大核心 2016年第8期628-630,共3页 Chinese Journal of Nephrology
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