桥本甲状腺炎与幽门螺旋杆菌感染的相关研究

目的 探讨桥本甲状腺炎与幽门螺旋杆菌感染的相关性.方法 选取200例桥本甲状腺炎患者,将患者甲状腺功能分为3组:1组(甲状腺功能减退)、2组(甲状腺功能亢进)、3组(甲状腺功能正常);选取200例健康体检者设为对照组4组.用碳14呼气实验检测幽门螺旋杆菌(Hp)感染.结果 1、2、3、4组的Hp感染阳性率分别为73.0%、67.2%、66.7%和44.5%.1、2、3组均比对照组有更高的Hp感染阳性率,而1、2、3组间Hp感染阳性差异无显著性.结论 Hp感染与桥本甲状腺炎相关,桥本甲状腺炎患者较正常人更容易感染Hp,为以后的诊治提供新的思路.

Objective To study the relationship between Hashimoto's thyroiditis and Helicobacter pylori(Hp) infection. Methods According to thyroid function,200 patients with Hashimoto's thyroiditis were divided into 3 groups:Group 1(hypothyroidism),Group 2(hyperthyroidism) and Group 3(euthyroidism);and 200 healthy controls was compared as Group 4. To examine Helicobacter pylori(Hp)infection by analyzing the outcomes of 14C-urea breath test. Results The positive rates of Helicobacter pylori(Hp)infection of Group 1,2,3,and 4 are 73.0%,67.2%, 66.7% and 44.5%. The positive rate of Hp infection of Group 1,2 and 3 were higher than control group,but there was no marked difference of HP infection rate among the three groups. Conclusion Hp infection is related to Hashimoto's thyroiditis and patients of Hashimoto's thyroiditis are more susceptible to Helicobacter pylori,which can provide new ideas for the diagnosis and treatment in the future.