目的探究关节镜下Bankart修复联合Remplissage术治疗复发性肩关节前脱位的疗效。方法回顾性分析郑州市第七人民医院2015年3月至2018年3月收治的31例肩关节前脱位患者资料,其中男24例,女7例;年龄19~44岁,平均(26.9±6.3)岁;左肩11例...目的探究关节镜下Bankart修复联合Remplissage术治疗复发性肩关节前脱位的疗效。方法回顾性分析郑州市第七人民医院2015年3月至2018年3月收治的31例肩关节前脱位患者资料,其中男24例,女7例;年龄19~44岁,平均(26.9±6.3)岁;左肩11例,右肩20例;运动伤23例,交通事故伤6例,其他伤2例;脱位次数3~8次,平均(5.1±1.6)次;末次脱位至手术时间2~13 d,平均(4.3±2.7)d。美国加利福尼亚大学洛杉矶分校(University of California at Los Angeles,UCLA)肩关节评分为(18.0±2.7)分,美国肩肘外科协会评分(American shoulder and elbow surgeons evaluation form,ASES)为(64.8±4.1)分。前屈上举角度为(168.8±4.7)°,外展外旋角度为(80.3±5.3)°。所有患者均通过肩关节CT三维重建确诊为复发性肩关节前脱位,并接受关节镜下Remplissage术联合Bankart修复术。随访评估患者再脱位发生率、UCLA评分和ASES评分改善情况以及肩关节功能恢复水平。结果31例均获随访,随访时间14~27个月,平均(17.1±4.1)个月。随访期间再脱位2例,其中半脱位1例,完全脱位1例。术后UCLA评分为(30.1±2.1)分,ASES评分为(87.1±4.0)分,与术前比较差异均有统计学意义(P<0.001)。术后前屈上举角度为(170.0±4.9)°,外展外旋角度为(77.0±4.4)°,与术前比较差异无统计学意义(P>0.05)。结论关节镜下Bankart修复联合Remplissage术治疗复发性肩关节前脱位,不影响肩关节外旋功能,有助于患者重返体育运动。盂肱关节骨缺损程度的准确评估不仅对术式的选择至关重要,而且还可降低复发率。展开更多
The applications of supramolecular metal-peptide assemblies as catalyst or catalyst precursor have recent attracted increasing attentions.In this work,a fragment of the amyloid β-peptide,NH_(2)-KLVFF-COOH,was assembl...The applications of supramolecular metal-peptide assemblies as catalyst or catalyst precursor have recent attracted increasing attentions.In this work,a fragment of the amyloid β-peptide,NH_(2)-KLVFF-COOH,was assembled into nanofilms with encapsulated Pd,Pt and Au nanoparticles(NPs)via a one-step room temperature electron induction method.The effects of building block,intermolecular interaction,driving force and side-chain on the assembly were investigated.The assembly mechanism was thereby proposed.The crosslinking of peptide monomers results in mainly random and unordered structures.The obtained metal-peptide assemblies are extremely stable in water at neutral pH for long term.However,the metal NPs are able to be responsively released under basic and reductive conditions.The released NPs show a high activity to catalyze the reduction of 4-nitrophenol.The present studies on assembly mechanism and responsive release will be helpful for the design of organic skeletons and also for the future development of peptide stabilized metallic NPs with applications beyond catalysts.展开更多
文摘目的探究关节镜下Bankart修复联合Remplissage术治疗复发性肩关节前脱位的疗效。方法回顾性分析郑州市第七人民医院2015年3月至2018年3月收治的31例肩关节前脱位患者资料,其中男24例,女7例;年龄19~44岁,平均(26.9±6.3)岁;左肩11例,右肩20例;运动伤23例,交通事故伤6例,其他伤2例;脱位次数3~8次,平均(5.1±1.6)次;末次脱位至手术时间2~13 d,平均(4.3±2.7)d。美国加利福尼亚大学洛杉矶分校(University of California at Los Angeles,UCLA)肩关节评分为(18.0±2.7)分,美国肩肘外科协会评分(American shoulder and elbow surgeons evaluation form,ASES)为(64.8±4.1)分。前屈上举角度为(168.8±4.7)°,外展外旋角度为(80.3±5.3)°。所有患者均通过肩关节CT三维重建确诊为复发性肩关节前脱位,并接受关节镜下Remplissage术联合Bankart修复术。随访评估患者再脱位发生率、UCLA评分和ASES评分改善情况以及肩关节功能恢复水平。结果31例均获随访,随访时间14~27个月,平均(17.1±4.1)个月。随访期间再脱位2例,其中半脱位1例,完全脱位1例。术后UCLA评分为(30.1±2.1)分,ASES评分为(87.1±4.0)分,与术前比较差异均有统计学意义(P<0.001)。术后前屈上举角度为(170.0±4.9)°,外展外旋角度为(77.0±4.4)°,与术前比较差异无统计学意义(P>0.05)。结论关节镜下Bankart修复联合Remplissage术治疗复发性肩关节前脱位,不影响肩关节外旋功能,有助于患者重返体育运动。盂肱关节骨缺损程度的准确评估不仅对术式的选择至关重要,而且还可降低复发率。
文摘The applications of supramolecular metal-peptide assemblies as catalyst or catalyst precursor have recent attracted increasing attentions.In this work,a fragment of the amyloid β-peptide,NH_(2)-KLVFF-COOH,was assembled into nanofilms with encapsulated Pd,Pt and Au nanoparticles(NPs)via a one-step room temperature electron induction method.The effects of building block,intermolecular interaction,driving force and side-chain on the assembly were investigated.The assembly mechanism was thereby proposed.The crosslinking of peptide monomers results in mainly random and unordered structures.The obtained metal-peptide assemblies are extremely stable in water at neutral pH for long term.However,the metal NPs are able to be responsively released under basic and reductive conditions.The released NPs show a high activity to catalyze the reduction of 4-nitrophenol.The present studies on assembly mechanism and responsive release will be helpful for the design of organic skeletons and also for the future development of peptide stabilized metallic NPs with applications beyond catalysts.