目的:观察参曲健脾颗粒治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease, AECOPD)合并营养不良患者的临床疗效。方法:选取2023年10月至2024年2月收治的112例符合纳入标准的AECOPD合并营...目的:观察参曲健脾颗粒治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease, AECOPD)合并营养不良患者的临床疗效。方法:选取2023年10月至2024年2月收治的112例符合纳入标准的AECOPD合并营养不良患者。采用随机数字表法随机分为观察组和对照组各56例。对照组为标准西医治疗,观察组为标准西医治疗联合参曲健脾颗粒治疗,总周期为2周。观察和比较两组患者治疗前后肺功能、血气分析指标以及CAT评分、ALB、BMI的变化,评估中医证候积分情况,并比较两组患者的临床疗效。结果:观察组在临床总有效率方面明显优于对照组(P 1)、FEV1占预计值的百分比(FEV1%pred)均有所升高,同时动脉氧分压(PaO2)、动脉二氧化碳分压(PaCO2)、CAT评分、血清白蛋白(albumin, ALB)、体重指数(body mass index, BMI)也有所改善,观察组的改善程度显著高于对照组(P Objective: To observe the clinical therapeutic effect of Shenqu Jianpi Granule in treating acute exacerbation of chronic obstructive pulmonary disease (AECOPD) complicated with malnutrition. Methods: A total of 112 patients with AECOPD and malnutrition who met the inclusion criteria were selected from October 2023 to February 2024. The patients were randomly divided into observation group and control group by random number table method. The control group was treated with standard Western medicine, and the observation group was treated with standard Western medicine combined with Shenqu Jianpi granule. The total cycle was 2 weeks. The changes of lung function, blood gas analysis index, CAT score, ALB and BMI of the two groups were observed and compared before and after treatment, the TCM syndrome score was evaluated, and the clinical efficacy of the two groups was compared. Results: The total effective rate of the observation group was significantly better than that of the control group (P 2), arterial partial pressure of carbon dioxide (PaCO2), CAT score, serum albumin (ALB), body mass index (BMI) were increased. The degree of improvement in the observation group was significantly higher than that in the control group (P < 0.05). Conclusion: Shenqu Jianpi Granule combined with conventional Western medicine in the treatment of AECOPD patients with malnutrition can effectively alleviate clinical symptoms, improve hypoxia, improve lung function and improve quality of life.展开更多
以Web of Science数据库所收录的2001-2017年运动与骨密度领域相关研究文献为基础,采用定量与定性相结合的方法,梳理该领域研究热点并对其动态变化趋势进行分析。结果显示,运动与骨密度领域高产出国家、机构、作者主要集中在欧美地区,...以Web of Science数据库所收录的2001-2017年运动与骨密度领域相关研究文献为基础,采用定量与定性相结合的方法,梳理该领域研究热点并对其动态变化趋势进行分析。结果显示,运动与骨密度领域高产出国家、机构、作者主要集中在欧美地区,领域研究热点主要包括运动、体力活动、骨、骨密度、骨质疏松等,热点研究群主要集中在绝经前后女性、儿童青少年、青年人和中年人。总体来看,研究由关注骨密度本身过渡到关注人的整体健康状况及生活质量,再从与健康相关的各个方面进行骨密度相关问题探讨。由此推测,不同健康状况人群骨密度维持或提高的运动处方构建,不同年龄、性别及体重人群骨密度维持或增长的个体化运动方案设计以及运动与骨密度关系机制可能会成为未来研究的主要方向。展开更多
文摘目的:观察参曲健脾颗粒治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease, AECOPD)合并营养不良患者的临床疗效。方法:选取2023年10月至2024年2月收治的112例符合纳入标准的AECOPD合并营养不良患者。采用随机数字表法随机分为观察组和对照组各56例。对照组为标准西医治疗,观察组为标准西医治疗联合参曲健脾颗粒治疗,总周期为2周。观察和比较两组患者治疗前后肺功能、血气分析指标以及CAT评分、ALB、BMI的变化,评估中医证候积分情况,并比较两组患者的临床疗效。结果:观察组在临床总有效率方面明显优于对照组(P 1)、FEV1占预计值的百分比(FEV1%pred)均有所升高,同时动脉氧分压(PaO2)、动脉二氧化碳分压(PaCO2)、CAT评分、血清白蛋白(albumin, ALB)、体重指数(body mass index, BMI)也有所改善,观察组的改善程度显著高于对照组(P Objective: To observe the clinical therapeutic effect of Shenqu Jianpi Granule in treating acute exacerbation of chronic obstructive pulmonary disease (AECOPD) complicated with malnutrition. Methods: A total of 112 patients with AECOPD and malnutrition who met the inclusion criteria were selected from October 2023 to February 2024. The patients were randomly divided into observation group and control group by random number table method. The control group was treated with standard Western medicine, and the observation group was treated with standard Western medicine combined with Shenqu Jianpi granule. The total cycle was 2 weeks. The changes of lung function, blood gas analysis index, CAT score, ALB and BMI of the two groups were observed and compared before and after treatment, the TCM syndrome score was evaluated, and the clinical efficacy of the two groups was compared. Results: The total effective rate of the observation group was significantly better than that of the control group (P 2), arterial partial pressure of carbon dioxide (PaCO2), CAT score, serum albumin (ALB), body mass index (BMI) were increased. The degree of improvement in the observation group was significantly higher than that in the control group (P < 0.05). Conclusion: Shenqu Jianpi Granule combined with conventional Western medicine in the treatment of AECOPD patients with malnutrition can effectively alleviate clinical symptoms, improve hypoxia, improve lung function and improve quality of life.
文摘以Web of Science数据库所收录的2001-2017年运动与骨密度领域相关研究文献为基础,采用定量与定性相结合的方法,梳理该领域研究热点并对其动态变化趋势进行分析。结果显示,运动与骨密度领域高产出国家、机构、作者主要集中在欧美地区,领域研究热点主要包括运动、体力活动、骨、骨密度、骨质疏松等,热点研究群主要集中在绝经前后女性、儿童青少年、青年人和中年人。总体来看,研究由关注骨密度本身过渡到关注人的整体健康状况及生活质量,再从与健康相关的各个方面进行骨密度相关问题探讨。由此推测,不同健康状况人群骨密度维持或提高的运动处方构建,不同年龄、性别及体重人群骨密度维持或增长的个体化运动方案设计以及运动与骨密度关系机制可能会成为未来研究的主要方向。
