For many different cancers,the advent of immunotherapy(IT)treatments,in particular immune checkpoint inhibitors,aimed at reviving the immune response against cancer cells,has led to a great improvement in terms of cli...For many different cancers,the advent of immunotherapy(IT)treatments,in particular immune checkpoint inhibitors,aimed at reviving the immune response against cancer cells,has led to a great improvement in terms of clinical benefit.Despite the success of IT,even in advanced metastatic cancers,some patients still fail to respond for reasons yet unclear(1,2).Yu et al.in an issue of Nature Medicine.展开更多
The burgeoning field of cancer immunology demands a change in the paradigm of cancer patient management. The understanding of the course of a given malignant disease should also include the host immune system as one o...The burgeoning field of cancer immunology demands a change in the paradigm of cancer patient management. The understanding of the course of a given malignant disease should also include the host immune system as one of the key factors in determining the patient's prognosis. Surgical and medical oncologists need to understand the basic and advanced applications of immunotherapies, which are rapidly evolving, and are nowadays an integral part of the armamentarium for the treatment of cancer patients. In the present work, we review the current knowledge concerning the immune landscape of colorectal cancer (CRC) patients with liver metastases, as recently discovered.展开更多
文摘For many different cancers,the advent of immunotherapy(IT)treatments,in particular immune checkpoint inhibitors,aimed at reviving the immune response against cancer cells,has led to a great improvement in terms of clinical benefit.Despite the success of IT,even in advanced metastatic cancers,some patients still fail to respond for reasons yet unclear(1,2).Yu et al.in an issue of Nature Medicine.
基金AIRC-Associazione Italiana per la Ricerca sul Cancro.
文摘The burgeoning field of cancer immunology demands a change in the paradigm of cancer patient management. The understanding of the course of a given malignant disease should also include the host immune system as one of the key factors in determining the patient's prognosis. Surgical and medical oncologists need to understand the basic and advanced applications of immunotherapies, which are rapidly evolving, and are nowadays an integral part of the armamentarium for the treatment of cancer patients. In the present work, we review the current knowledge concerning the immune landscape of colorectal cancer (CRC) patients with liver metastases, as recently discovered.
