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Effects of Health Education with Problem-Based Learning Approaches on the Knowledge, Attitude, Practice and Coping Skills of Women with High-Risk Pregnancies in Plateau Areas
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作者 ying wu Suolang Sezhen +5 位作者 Renqing Yuzhen Hong Wei Zhijuan Zhan Baima Hongying Yuhong Zhang Lihong Liu 《Open Journal of Nursing》 2024年第5期192-199,共8页
Objective: Given the unique cultural background, way of life, and physical environment of the Tibetan Plateau, this study aims to investigate the effects of health education using problem-based learning (PBL) approach... Objective: Given the unique cultural background, way of life, and physical environment of the Tibetan Plateau, this study aims to investigate the effects of health education using problem-based learning (PBL) approaches on the knowledge, attitude, practice, and coping skills of women with high-risk pregnancies in this region. Methods: 76 high-risk pregnancy cases were enrolled at Tibet’s Linzhi People’s Hospital between September 2023 and April 2024. 30 patients admitted between September 2023 and December 2023 were selected as the control group and were performed with regular patient education. 46 patients admitted between January 2024 and April 2024 were selected as the observation group and were performed regular patient education with problem-based learning approaches. Two groups’ performance on their health knowledge, attitude, practice and coping skills before and after interventions were evaluated, and patient satisfaction were measured at the end of the study. Results: There was no statistical significance (P P P Conclusions: Health education with problem-based learning approaches is worth promoting as it can help high-risk pregnant women in plateau areas develop better health knowledge, attitude and practice and healthier coping skills. Also, it can improve patient sanctification. 展开更多
关键词 Plateau Areas Patients with High-Risk Pregnancies Problem-Based Learning Health Education Health Knowledge Attitude and Practice Coping Skills
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Application of Patient Simulators Combined with Internet plus Scenario Simulation Teaching Models on Intravenous Infusion Nursing Education in China
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作者 ying wu Yun Chen +5 位作者 Liuyan Zhang Guohua Huang Jinai He Yutong Li Yuzhen Renqing Zhijuan Zhan 《Journal of Biosciences and Medicines》 2024年第1期64-71,共8页
Objective: To explore the effectiveness of applying patient simulators combined with Internet Plus scenario simulation teaching models on intravenous (IV) infusion nursing education, and to provide scientific evidence... Objective: To explore the effectiveness of applying patient simulators combined with Internet Plus scenario simulation teaching models on intravenous (IV) infusion nursing education, and to provide scientific evidence for the implementation of advanced teaching models in future nursing education. Methods: Enrolled 60 nurses who took the IV infusion therapy training program in our hospital from January 2022 to December 2023 for research. 30 nurses who were trained in traditional teaching models from January to December 2022 were selected as the control group, and 30 nurses who were trained with simulation-based teaching models with methods including simulated patients, internet, online meetings which can be replayed and scenario simulation, etc. from January to December 2023 were selected as the experimental group. Evaluated the learning outcomes based on the Competency Inventory for Nursing Students (CINS), Problem-Solving Inventory (PSI), comprehensive learning ability, scientific research ability, and proficiency in the theoretical knowledge and practical skills of IV infusion therapy. Nursing quality, the incidence of IV infusion therapy complications and nurse satisfaction with different teaching models were also measured. Results: The scientific research ability, PSI scores, CINS scores, and comprehensive learning ability of the experimental group were better than those of the control group (P 0.05), and their assessment results of practical skills, nursing quality of IV infusion therapy during training, and satisfaction with teaching models were all better than those of the control group with statistical significance (P < 0.05). The incidence of IV infusion therapy complications in the experimental group was lower than that in the control group, indicating statistical significance (P < 0.05). Conclusions: Teaching models based on patient simulators combined with Internet Plus scenario simulation enable nursing students to learn more directly and practice at any time and in any place, and can improve their proficiency in IV infusion theoretical knowledge and skills (e.g. PICC catheterization), core competencies, problem-solving ability, comprehensive learning ability, scientific research ability and the ability to deal with complicated cases. Also, it helps provide high-quality nursing education, improve the nursing quality of IV therapy, reduce the incidence of related complications, and ensure the safety of patients with IV therapy. 展开更多
关键词 Specialty of Intravenous Infusion Therapy Nursing Education Patient Simulators Internet Plus Scenario Simulation Teaching Model
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Effect of Different Drying Methods on the Volatile Compounds Jinmudan Oolong Tea 被引量:2
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作者 Hui-Jing Xu ying wu +3 位作者 Qing Wei Fei-Long Cui Jing Zhu Ling-Yun Zhang 《茶叶》 2013年第4期362-369,共8页
Jinmudan,a new tea variety from Fujian Province has an excellent quality with a unique aroma like magnolia frogrance.To monitor the changes in the tea volatile compounds during the Jinmudan Oolong tea manufacturing(dr... Jinmudan,a new tea variety from Fujian Province has an excellent quality with a unique aroma like magnolia frogrance.To monitor the changes in the tea volatile compounds during the Jinmudan Oolong tea manufacturing(drying) process,the volatiles of tea samples were extracted and analyzed.Characteristic volatile compounds in Jinmudan Oolong tea were nerolidol,α-farnesene,linolenic acid,palmitic acid,indole,phenylacetaldehyde,cisjasmone,β-phenylethanol,etc.The content of nerolidol was the highest in four tested samples.The composition of the volatile compounds in microwave drying sample was simple,but its concentration was high,in which the main volatile compounds were alcohols and esters.The processing with combination of traditional drying craft and modern aroma-improvement technique could obviously improve the tea aroma,especially in level of epoxy linalool and jasmine lactone. 展开更多
关键词 挥发性化合物 干燥方法 乌龙茶 茶叶香气 橙花叔醇 茶叶品种 苯基乙醇 测试样本
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中小学心理健康教育数字化平台建设评价标准的构建
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作者 孙炳海 武莹 孙长康 《中国教育信息化》 2024年第4期41-50,共10页
科学建设心理健康教育数字化平台,是统筹推进心理健康教育与数字化技术深度融合、引领新时代学校心理健康教育服务高质量发展的关键一环。浙江省儿童青少年心理健康与危机干预智能实验室通过近二十年建设过程与实践探索,在浙江省各区县... 科学建设心理健康教育数字化平台,是统筹推进心理健康教育与数字化技术深度融合、引领新时代学校心理健康教育服务高质量发展的关键一环。浙江省儿童青少年心理健康与危机干预智能实验室通过近二十年建设过程与实践探索,在浙江省各区县心理健康教育数字化实践中提炼形成《中小学心理健康教育数字化平台建设评价标准》,提出十一条评价标准,包括安全性隐私保护、基础性理论支持、无感化数据采集、精准化算法运行、自动化预警提示、自适应辨识调整、成长性科学研究、跨部门协同保障、丰富的课程资源、个性化智能推送、闭环式系统服务。旨在多维、全面地为数字化平台高质量建设提供参照体系,实现数字化平台建设的科学性、安全性、智能性,助力数字化心理健康教育服务高质量建设。 展开更多
关键词 中小学心理健康教育 教育数字化 数字化平台建设 心理赋能 数字赋能
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植物免疫诱抗剂对大豆苗期生长的影响 被引量:1
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作者 任晓旭 应武 +3 位作者 黄雨晴 徐盛春 阮松林 张胜 《大豆科学》 CAS CSCD 北大核心 2024年第1期81-87,共7页
植物免疫诱抗剂具有诱导植物抗性和促进生长的作用,为比较8个不同植物免疫诱抗剂处理对大豆幼苗生长的影响差异,以浙鲜19为试验材料,对大豆幼苗的出苗率、株高、根长、叶长、叶宽、生物量等生物性状及叶片叶绿素相对含量(SPAD值)、多酚... 植物免疫诱抗剂具有诱导植物抗性和促进生长的作用,为比较8个不同植物免疫诱抗剂处理对大豆幼苗生长的影响差异,以浙鲜19为试验材料,对大豆幼苗的出苗率、株高、根长、叶长、叶宽、生物量等生物性状及叶片叶绿素相对含量(SPAD值)、多酚氧化酶(PPO)活性、苯丙氨酸解氨酶(PAL)活性等理化指标进行了测定。结果表明:不同植物免疫诱抗剂处理对大豆幼苗的生长表现各异,喷施海藻肥处理(HZF)可以增加出苗率、株高、鲜重生物量等指标,保康灵(BKL-2)处理对干重生物量的提高最为显著,达到1.91 g,喷施芸苔素内酯处理(YCS)可以明显增加大豆叶片SPAD值。所有处理中BKL-2处理的PPO和PAL活性相对于CK均有提高,分别提高41.18%和16.14%。BKL-2处理浓度4 g·L^(-1)的效果优于2和6 g·L^(-1)。BKL-2、HZF和MLT处理对大豆幼苗有明显的促生长作用,建议可在大豆生产上应用。 展开更多
关键词 植物免疫诱抗剂 大豆 生物量 促生长 抗性酶
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二氢杨梅素对运动性骨骼肌损伤的保护作用及机制研究
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作者 吴瑛 王大伟 +5 位作者 李军 许贤杰 高志丹 李鸿雁 张勇 刘鹏 《Chinese Medical Sciences Journal》 CAS CSCD 2024年第1期46-53,I0005,共9页
目的探讨二氢杨梅素(dihydromyricetin,DHM)对运动训练后小鼠骨骼肌损伤的保护作用及潜在机制。方法将成年雄性C57BL/6J小鼠随机分为安静对照组(CG)、运动组(EG)、二氢杨梅素(100mg/kg·d)+运动组(DHM组)。干预期4周,同时进行运动训... 目的探讨二氢杨梅素(dihydromyricetin,DHM)对运动训练后小鼠骨骼肌损伤的保护作用及潜在机制。方法将成年雄性C57BL/6J小鼠随机分为安静对照组(CG)、运动组(EG)、二氢杨梅素(100mg/kg·d)+运动组(DHM组)。干预期4周,同时进行运动训练,每天1小时。训练结束后的次日,EG组和DHM组进行一次坡度为0、速度为18 m/min、持续90 min的跑台运动。运动结束后24小时按组别取材,测定血清肌酸激酶(creatine kinase,CK)、乳酸脱氢酶(lactate dehydrogenase,LDH)和总超氧化物歧化酶(total superoxide dismutase,T-SOD)活性、丙二醛(malondialdehyde,MDA)含量和骨骼肌线粒体酶复合体Ⅰ和Ⅱ的活性,观察骨骼肌病理学组织形态变化。免疫印迹法(Western blot)检测线粒体功能相关通路的蛋白表达。结果与EG组相比,DHM组小鼠骨骼肌形态改变和线粒体损伤明显减轻。DHM显著抑制了运动后骨骼肌损伤的标志物CK和LDH及脂质过氧化水平,提高了骨骼肌T-SOD活性。Western blot结果显示,DHM显著增加小鼠骨骼肌沉默调节蛋白3(SIRT3)、雌激素相关受体α(EERα)和过氧化物酶体增殖物激活受体-γ共激活因子-1α(peroxisome proliferator-activated receptor gamma coactivator-1 alpha,PGC-1α)的表达。结论DHM有助于减轻小鼠运动性骨骼肌损伤,其机制可能是DHM可激活肌肉SIRT3信号通路,促进大强度运动后骨骼肌线粒体结构和功能的恢复。 展开更多
关键词 二氢杨梅素 运动性骨骼肌损伤 线粒体功能
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Development of a new cerebral ischemia reperfusion model of Mongolian gerbils and standardized evaluation system 被引量:2
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作者 ying wu Caijiao Hu +9 位作者 Zhihui Li Feiyang Li Jianyi Lv Meng Guo Xin Liu Changlong Li Xueyun Huo Zhenwen Chen Lifeng Yang Xiaoyan Du 《Animal Models and Experimental Medicine》 CAS CSCD 2024年第1期48-55,共8页
Background:The Mongolian gerbil is an excellent laboratory animal for preparing the cerebral ischemia model due to its inherent deficiency in the circle of Willis.However,the low incidence and unpredictability of symp... Background:The Mongolian gerbil is an excellent laboratory animal for preparing the cerebral ischemia model due to its inherent deficiency in the circle of Willis.However,the low incidence and unpredictability of symptoms are caused by numerous complex variant types of the circle.Additionally,the lack of an evaluation system for the cer-ebral ischemia/reperfusion(I/R)model of gerbils has shackled the application of this model.Methods:We created a symptom-oriented principle and detailed neurobehavioral scoring criteria.At different time points of reperfusion,we analyzed the alteration in locomotion by rotarod test and grip force score,infarct volume by triphenyltetrazo-lium chloride(TTC)staining,neuron loss using Nissl staining,and histological charac-teristics using hematoxylin-eosin(H&E)straining.Results:With a successful model rate of 56%,32 of the 57 gerbils operated by our method harbored typical features of cerebral I/R injury,and the mortality rate in the male gerbils was significantly higher than that in the female gerbils.The suc-cessfully prepared I/R gerbils demonstrated a significant reduction in motility and grip strength at 1 day after reperfusion;formed obvious infarction;exhibited typi-cal pathological features,such as tissue edema,neuronal atrophy and death,and vacuolated structures;and were partially recovered with the extension of reperfu-sion time.Conclusion:This study developed a new method for the unilateral common carotid artery ligation I/R model of gerbil and established a standardized evaluation system for this model,which could provide a new cerebral I/R model of gerbils with more practical applications. 展开更多
关键词 ISCHEMIA/REPERFUSION Mongolian gerbil standardized model system unilateral carotid occlusion
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Highly Aligned Graphene Aerogels for Multifunctional Composites 被引量:1
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作者 ying wu Chao An +4 位作者 Yaru Guo Yangyang Zong Naisheng Jiang Qingbin Zheng Zhong‑Zhen Yu 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第6期276-342,共67页
Stemming from the unique in-plane honeycomb lattice structure and the sp^(2)hybridized carbon atoms bonded by exceptionally strong carbon–carbon bonds,graphene exhibits remarkable anisotropic electrical,mechanical,an... Stemming from the unique in-plane honeycomb lattice structure and the sp^(2)hybridized carbon atoms bonded by exceptionally strong carbon–carbon bonds,graphene exhibits remarkable anisotropic electrical,mechanical,and thermal properties.To maximize the utilization of graphene’s in-plane properties,pre-constructed and aligned structures,such as oriented aerogels,films,and fibers,have been designed.The unique combination of aligned structure,high surface area,excellent electrical conductivity,mechanical stability,thermal conductivity,and porous nature of highly aligned graphene aerogels allows for tailored and enhanced performance in specific directions,enabling advancements in diverse fields.This review provides a comprehensive overview of recent advances in highly aligned graphene aerogels and their composites.It highlights the fabrication methods of aligned graphene aerogels and the optimization of alignment which can be estimated both qualitatively and quantitatively.The oriented scaffolds endow graphene aerogels and their composites with anisotropic properties,showing enhanced electrical,mechanical,and thermal properties along the alignment at the sacrifice of the perpendicular direction.This review showcases remarkable properties and applications of aligned graphene aerogels and their composites,such as their suitability for electronics,environmental applications,thermal management,and energy storage.Challenges and potential opportunities are proposed to offer new insights into prospects of this material. 展开更多
关键词 Highly aligned graphene aerogels Quantitative characterization of alignment Multifunctional composites Anisotropic properties Multifunctional applications
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Investigation of the epidemiology,pathogenicity and immunogenicity of Bordetella bronchiseptica isolated from cats and dogs in China from 2021 to 2023 被引量:1
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作者 Qinghua Shang Wenhui Gao +7 位作者 Xiangting Zhang Jianqing Zhao ying wu Haoqi Li Ming Zhou Zhen F.Fu Chengguang Zhang Ling Zhao 《Animal Diseases》 CAS 2024年第3期156-172,共17页
Bordetella bronchiseptica(Bb)is recognized as a leading cause of respiratory diseases in dogs and cats.However,epidemiological data on Bb in dogs and cats in China are still limited,and there is no commercially availa... Bordetella bronchiseptica(Bb)is recognized as a leading cause of respiratory diseases in dogs and cats.However,epidemiological data on Bb in dogs and cats in China are still limited,and there is no commercially available vaccine.Live vaccines containing Bb that are widely used abroad are generally efective but can establish latency and potentially reactivate to cause illness in some immunodefcient vaccinated recipients,raising safety concerns.In this study,34 canine-derived and two feline-derived Bb strains were isolated from 1809 canine and 113 feline nasopharyngeal swab samples collected from eight provinces in China from 2021 to 2023.The PCR results showed that the percentage of positive Bb was 22.94%(441/1922),and more than 90%of the Bb isolates had four virulence factor-encoding genes(VFGs),namely,fhaB,prn,betA and dnt.All the isolated strains displayed a multidrug-resistant phenotype.The virulence of 10 Bb strains isolated from dogs with respiratory symptoms was tested in mice,and we found that eight isolates were highly virulent.Furthermore,the eight Bb isolates with high virulence were inactivated and intramuscularly injected into mice,and three Bb strains(WH1218,WH1203 and WH1224)with the best protective efcacy were selected.Dogs immunized with these three strains exhibited strong protection against challenge with the Bb feld strain WH1218.Ultimately,the WH1218 strain with the greatest protection in dogs was selected as the vaccine candidate.Dogs and cats that received a vaccine containing 109 CFU of the inactivated WH1218 strain showed complete protection against challenge with the Bb feld strain WH1218.This study revealed that Bb is an important pathogen that causes respiratory diseases in domestic dogs and cats in China,and all the isolates exhibited multidrug resistance.The present work contributes to the current understanding of the prevalence,antimicrobial resistance,and virulence genes of Bb in domestic dogs and cats.Additionally,our results suggest that the WH1218 strain is a promising candidate safe and efcacious inactivated Bb vaccine. 展开更多
关键词 Bordetella bronchiseptica Epidemiological investigation PATHOGENICITY IMMUNOGENICITY Inactivated vaccine
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Utlra-fast hydrolysis performance of MgH_(2) catalyzed by Ti-Zr-Fe-Mn-Cr-V high-entropy alloys
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作者 Jinting Chen Tingting Xu +7 位作者 Zeyu Zhang Jinghan Zhang Haixiang Huang Bogu Liu Yawei Li Jianguang Yuan Bao Zhang ying wu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第11期77-86,共10页
Hydrogen energy is one of the ideal energy alternatives and the upstream of the hydrogen industry chain is hydrogen production,which can be achieved via the reaction of inorganic materials with water,known as hydrolys... Hydrogen energy is one of the ideal energy alternatives and the upstream of the hydrogen industry chain is hydrogen production,which can be achieved via the reaction of inorganic materials with water,known as hydrolysis.Among inorganic materials,the high hydrogen capacity for hydrolysis of MgH_(2)(15.2 wt%)makes it a promising material for hydrogen production via hydrolysis.However,the dense Mg(OH)_(2) passivation layer will block the reaction between MgH_(2) and the solution,resulting in low hydrogen yield and sluggish hydrolysis kinetics.In this work,the hydrogenyield and hydrogen generation rate of MgH_(2) are considerably enhanced by adding Ti-Zr-Fe-Mn-Cr-V high-entropy alloys(HEAs) for the first time.In particular.the MgH_(2)-3 wt% TiZrFe_(1.5)MnCrV_(0.5)(labelled as MgH_(2)-3 wt% Fe_(1.5)) composite releases 1526.70 mL/g H_(2) within 5 min at 40℃,and the final hydrolysis conversion rate reaches 95.62% within 10 min.The mean hydrogen generation rate of the MgH_(2)-3 wt% Fe_(1.5) composite is 289.16 mL/g/min,which is 2.38 times faster than that of pure MgH_(2).Meanwhile,the activation energy of the MgH_(2)-3 wt% Fe_(1.5) composite is calculated to be 12.53 kJ/mol. The density functional theory(DFT) calculation reveals that the addition of HEAs weakens the Mg-H bonds and accelerates the electron transfer between MgH_(2) and HEAs,Combined with the cocktail effect of HEAs as well as the formation of more interfaces and micro protocells,the hydrolysis performance of MgH_(2) is considerably improved.This work provides an appealing prospect for real-time hydrogen supply and offers a new effective strategy for improving the hydrolysis performance of MgH_(2). 展开更多
关键词 Mg-based materials High-entropy alloys HYDROLYSIS Hydrogen generation Cocktail effect CATALYSIS
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Genome wide association analysis identifies candidate genes for fruit quality and yield in Actinidia eriantha
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作者 yingzhen Wang ying wu +7 位作者 Xinlei Wang Wangmei Ren Qinyao Chen Sijia Zhang Feng Zhang Yunzhi Lin Junyang Yue Yongsheng Liu 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第6期1929-1939,共11页
Quality and yield are the primary concerns in kiwifruit breeding,but research on the genetic mechanisms of fruit size,shape,and ascorbic acid(ASA)content is currently very limited,which restricts the development of ki... Quality and yield are the primary concerns in kiwifruit breeding,but research on the genetic mechanisms of fruit size,shape,and ascorbic acid(ASA)content is currently very limited,which restricts the development of kiwifruit molecular breeding.In this study,we obtained a total of 8.88 million highly reliable single nucleotide polymorphism(SNP)markers from 140 individuals from the natural hybrid offspring of Actinidia eriantha cv.‘White’using whole genome resequencing technology.A genome-wide association study was conducted on eight key agronomic traits,including single fruit weight,fruit shape,ASA content,and the number of inflorescences per branch.A total of 59 genetic loci containing potential functional genes were located,and candidate genes related to single fruit weight,fruit length,ASA content,number of inflorescences per branch and other traits were identified within the candidate interval,such as AeWUSCHEL,AeCDK1(cell cycle dependent kinase),AeAO1(ascorbic oxidase)and AeCO1(CONSTANS-like 4).After constructing an RNAi vector for AeAO1 and injecting it into the fruit of cv.‘Midao 31’to interfere with the expression of the AeAO1 gene,the results showed that the activity of ascorbic oxidase in the fruit of‘Midao 31’significantly decreased,while the content of ASA significantly increased.This study provides valuable insights into the genetic basis of variation in A.eriantha fruit traits,which may benefit molecular marker-assisted breeding efforts. 展开更多
关键词 Actinidia eriantha GWAS SNP QTLS fruit quality
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Configuring single-layer MXene nanosheet onto natural wood fiber via C-Ti-C covalent bonds for high-stability Li-S batteries
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作者 Yangyang Chen Yu Liao +5 位作者 ying wu Lei Li Zhen Zhang Sha Luo Yiqiang wu Yan Qing 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第8期701-711,I0016,共12页
Lithium-sulfur batteries(LSBs)are considered promising candidates for next-generation battery technologies owing to their outstanding theoretical energy density and cost-effectiveness.However,the low conductivity and ... Lithium-sulfur batteries(LSBs)are considered promising candidates for next-generation battery technologies owing to their outstanding theoretical energy density and cost-effectiveness.However,the low conductivity and polysulfide shuttling effect of S cathodes severely hamper the practical performance of LSBs.Herein,in situ-generated single layer MXene nanosheet/hierarchical porous carbonized wood fiber(MX/PCWF)composites are prepared via a nonhazardous eutectic activation strategy coupled with pyrolysis-induced gas diffusion.The unique architecture,wherein single layer MXene nanosheets are constructed on carbonized wood fiber walls,ensures rapid polysulfide conversion and continuous electron transfer for redox reactions.The C-Ti-C bonds formed between MXene and PCWF can considerably expedite the conversion of polysulfides,effectively suppressing the shuttle effect.An impressive capacity of 1301.1 m A h g^(-1)at 0.5 C accompanied by remarkable stability is attained with the MX/PCWF host,as evidenced by the capacity maintenance of 722.6 m A h g^(-1)after 500 cycles.Notably,the MX/PCWF/S cathode can still deliver a high capacity of 886.8 m A h g^(-1)at a high S loading of 5.6 mg cm^(-2).The construction of two-dimensional MXenes on natural wood fiber walls offers a competitive edge over S-based cathode materials and demonstrates a novel strategy for developing high-performance batteries. 展开更多
关键词 Lithium-sulfur batteries S cathodes MXene nanosheets Wood fiber C-Ti-C bonds
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Bandgap adjustment of a sandwich-like acoustic metamaterial plate with a frequency-displacement feedback control method
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作者 Jianing LIU Jinqiang LI ying wu 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第10期1807-1820,共14页
Several types of acoustic metamaterials composed of resonant units have been developed to achieve low-frequency bandgaps.In most of these structures,bandgaps are determined by their geometric configurations and materi... Several types of acoustic metamaterials composed of resonant units have been developed to achieve low-frequency bandgaps.In most of these structures,bandgaps are determined by their geometric configurations and material properties.This paper presents a frequency-displacement feedback control method for vibration suppression in a sandwich-like acoustic metamaterial plate.The band structure is theoretically derived using the Hamilton principle and validated by comparing the theoretical calculation results with the finite element simulation results.In this method,the feedback voltage is related to the displacement of a resonator and the excitation frequency.By applying a feedback voltage on the piezoelectric fiber-reinforced composite(PFRC)layers attached to a cantilever-mass resonator,the natural frequency of the resonator can be adjusted.It ensures that the bandgap moves in a frequency-dependent manner to keep the excitation frequency within the bandgap.Based on this frequency-displacement feedback control strategy,the bandgap of the metamaterial plate can be effectively adjusted,and the vibration of the metamaterial plate can be significantly suppressed. 展开更多
关键词 acoustic metamaterial Hamilton principle electromechanical coupling vibration control local resonance
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Targeting colorectal cancer with Herba Patriniae and Coix seed:Network pharmacology,molecular docking,and in vitro validation
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作者 Cheng-Lei Wang Bing-Wei Yang +8 位作者 Xin-Yan Wang Xue Chen Wei-Dong Li Hao-Yu Zhai ying wu Mu-YaoCui Jia-He wu Qing-Hui Meng Nan Zhang 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第8期3539-3558,共20页
BACKGROUND Herba Patriniae and Coix seed(HC)constitute a widely utilized drug combination in the clinical management of colorectal cancer(CRC)that is known for its diuretic,anti-inflammatory,and swelling-reducing prop... BACKGROUND Herba Patriniae and Coix seed(HC)constitute a widely utilized drug combination in the clinical management of colorectal cancer(CRC)that is known for its diuretic,anti-inflammatory,and swelling-reducing properties.Although its efficacy has been demonstrated in a clinical setting,the active compounds and their mechanisms of action in CRC treatment remain to be fully elucidated.AIM To identify the active,CRC-targeting components of HC and to elucidate the mechanisms of action involved.METHODS Active HC components were identified and screened using databases.Targets for each component were predicted.CRC-related targets were obtained from human gene databases.Interaction targets between HC and CRC were identified.A“drug-ingredient-target”network was created to identify the core components and targets involved.Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analyses were conducted to elucidate the key pathways involved.Molecular docking between core targets and key components was executed.In vitro experiments validated core monomers.RESULTS Nineteen active components of HC were identified,with acacetin as the primary active compound.The predictive analysis identified 454 targets of the active compounds in HC.Intersection mapping with 2685 CRC-related targets yielded 171 intervention targets,including 30 core targets.GO and KEGG analyses indicated that HC may influence the phosphoinositide 3-kinase(PI3K)/Akt signaling pathway.Molecular docking showed that acacetin exhibited an optimal interaction with AKT1,identifying PI3K,AKT,and P53 as key genes likely targeted by HC during CRC treatment.Acacetin inhibited HT-29 cell proliferation and migration,as well as promoted apoptosis,in vitro.Western blotting analysis revealed increased p53 and cleaved caspase-3 expression and decreased levels of p-PI3K,p-Akt,and survivin,which likely contributed to CRC apoptosis.CONCLUSION Acacetin,the principal active compound in the HC pair,inhibited the proliferation and migration of HT-29 cells and promoted apoptosis through the PI3K/Akt/p53 signaling pathway. 展开更多
关键词 Colorectal cancer Baijiangcao(Herba Patriniae) Yiyiren(Coix seed) ACACETIN PROLIFERATION MIGRATION Apoptosis Network pharmacology
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Effects of comprehensive nursing with cognitive behavioral therapy in orthodontic osteodilated arch treatment
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作者 Xin Yang Zeng-Xiang Wang +3 位作者 Yu-Xing Tian Chao Peng Hui-Ning Yang ying wu 《World Journal of Clinical Cases》 SCIE 2024年第22期5051-5058,共8页
BACKGROUND This work explored the effects of cognitive behavior therapy(CBT)-based comprehensive nursing intervention(CNI)mode in arch expansion to treat patients with orthodontic osteodilated arch(OOA).AIM To explore... BACKGROUND This work explored the effects of cognitive behavior therapy(CBT)-based comprehensive nursing intervention(CNI)mode in arch expansion to treat patients with orthodontic osteodilated arch(OOA).AIM To explore the application effect of CBT-based CNI model in orthodontic expansion arch treatment.METHODS Using convenient sampling method,81 patients with OOA were selected and rolled into a control group(Ctrl group,40 cases)and an observation group(Obs group,41 cases).During the treatment,patients in the Ctrl group received routine nursing intervention mode,and the those in the Obs group received CBT mode on the basis of this.Before and after intervention,the incidence of oral mucositis,the mastery rate of correct arch expansion method,self-rating anxiety scale score,soft scale index,and plaque index were compared for patients in different groups.In addition,satisfaction and complications were comparatively analyzed.RESULTS Incidence of oral mucositis in the Obs group was lower(14.6%vs 38.5%),and the mastery rate of correct arch expansion method was obviously higher(90.2%vs 55.0%)was obviously higher(all P<0.05).Meanwhile,the soft scale index and plaque index in the Obs group were much lower(P<0.05).The compliance(90.24%)and satisfaction(95.12%)in the Obs group were greatly higher(P<0.05).CONCLUSION The CBT-based CNI mode greatly improved the mastery rate of correct arch expansion method during arch expansion in treating patients with OOA and enhanced the therapeutic effect of arch expansion and the oral health of patients,improving the patient compliance. 展开更多
关键词 Orthodontic osteodilated arch Cognitive behavior therapy Comprehensive nursing intervention mode Nursing effect Pain management Oral care
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Key technology and application of AB_(2) hydrogen storage alloy in fuel cell hydrogen supply system
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作者 Ming Yao Jianguang Yuan +3 位作者 Bao Zhang Youhua Yan Shaoxiong Zhou ying wu 《Materials Reports(Energy)》 EI 2024年第1期113-122,共10页
At present,there is limited research on the application of fuel cell power generation system technology using solid hydrogen storage materials,especially in hydrogen-assisted two-wheelers.Considering the disadvantages... At present,there is limited research on the application of fuel cell power generation system technology using solid hydrogen storage materials,especially in hydrogen-assisted two-wheelers.Considering the disadvantages of low hydrogen storage capacity and poor kinetics of hydrogen storage materials,our primary focus is to achieve smooth hydrogen ab-/desorption over a wide temperature range to meet the requirements of fuel cells and their integrated power generation systems.In this paper,the Ti_(0.9)Zr_(0.1)Mn_(1.45)V_(0.4)Fe_(0.15) hydrogen storage alloy was successfully prepared by arc melting.The maximum hydrogen storage capacity reaches 1.89 wt% at 318 K.The alloy has the capability to absorb 90% of hydrogen storage capacity within 50 s at 7 MPa and release 90% of hydrogen within 220 s.Comsol Multiphysics 6.0 software was used to simulate the hydrogen ab-/desorption processes of the tank.The flow rate of cooling water during hydrogen absorption varied in a gradient of(0.02 t x)m s^(-1)(x=0,0.02,0.04,0.06,0.08,0.1,0.12).Cooling water flow rate is positively correlated with the hydrogen absorption rate but negatively correlated with the cost.When the cooling rate is 0.06 m s^(-1),both simulation and experimentation have shown that the hydrogen storage tank is capable of steady hydrogen desorption for over 6 h at a flow rate of 2 L min^(-1).Based on the above conclusions,we have successfully developed a hydrogen-assisted two-wheeler with a range of 80 km and achieved regional demonstration operations in Changzhou and Shaoguan.This paper highlights the achievements of our team in the technological development of fuel cell power generation systems using solid hydrogen storage materials as hydrogen storage carriers and their application in twowheelers in recent years. 展开更多
关键词 AB_(2)hydrogen storage alloy Hydrogen storage tanks Simulation Hydrogen-electric coupling system Power-assisted two-wheelers
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631名医护人员对慢性阻塞性肺疾病吸入治疗相关知识的掌握现状调查分析 被引量:5
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作者 杨霞 袁星竹 +1 位作者 吴颖 冯梅 《中国现代医学杂志》 CAS 北大核心 2021年第7期93-96,共4页
目的探讨医护人员对慢性阻塞性肺疾病吸入治疗相关知识的掌握现状,为医护人员吸入治疗相关知识培训提供依据。方法随机选取32所二级乙等以上医院631名医护人员作为研究对象,采用自制问卷线上调查(问卷星)的方式收集资料,调查分析医护人... 目的探讨医护人员对慢性阻塞性肺疾病吸入治疗相关知识的掌握现状,为医护人员吸入治疗相关知识培训提供依据。方法随机选取32所二级乙等以上医院631名医护人员作为研究对象,采用自制问卷线上调查(问卷星)的方式收集资料,调查分析医护人员对慢性阻塞性肺疾病吸入治疗相关知识的掌握情况。结果631名医护人员对慢性阻塞性肺疾病吸入治疗相关知识平均得分为9.97分,评分结果为不及格。不同职别、职称、工作年限医护人员比较,职称越低、工作年限越短的医护人员,吸入治疗知识掌握率越低(P<0.05)。接受过吸入治疗知识培训的医护人员得分高于未接受过培训的医护人员,且不同培训方式对医护人员吸入治疗知识掌握有重要影响(P<0.05),新型网络培训方式深受医护人员喜爱。结论医护人员吸入治疗相关知识掌握不足,尤其是低年制护士需重点培训。新型网络培训方式深受医护人员喜爱,建议在临床工作中推广应用。 展开更多
关键词 医护人员 吸入治疗 知识 掌握 分析
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线上线下混合式实验教学模式的改革与探索 被引量:12
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作者 章建东 吴莹 +3 位作者 严吉林 姚英明 赵蓓 姚建林 《大学化学》 CAS 2022年第2期15-22,共8页
大学化学实验课程是培养材料、化学、化工等专业人才应用基本操作和理论解决实际问题的综合性实践训练环节。文章探讨了当前大学化学实验发展由于受到仪器设备大型化、专业化、成本大、更新快等因素限制出现瓶颈,设计了线上线下混合实... 大学化学实验课程是培养材料、化学、化工等专业人才应用基本操作和理论解决实际问题的综合性实践训练环节。文章探讨了当前大学化学实验发展由于受到仪器设备大型化、专业化、成本大、更新快等因素限制出现瓶颈,设计了线上线下混合实验教学模式,进行相应的软硬件建设,并开展线上线下混合式实验教学模式的改革与探索。该教学模式具有良好的教学效果,并且可复制可推广,为创新人才的培养和实验教学的创新提供了有益的借鉴。 展开更多
关键词 线上线下混合式教学 实验教学 大学化学
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不同生物刺激剂对鲜食玉米产量和品质的影响 被引量:10
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作者 应武 骆乐谈 +1 位作者 阮松林 李金文 《中国农学通报》 2020年第17期89-94,共6页
为研究生物刺激剂对玉米的增产提质效果,试验探讨不同生物刺激剂对玉米的产量和品质方面的影响,为鲜食玉米的优质高产栽培提供技术支撑。以鲜食玉米‘钱江糯3号’为试验品种,以3种生物刺激剂(阿美滋、美基、保康灵1号)为供试药剂,设置6... 为研究生物刺激剂对玉米的增产提质效果,试验探讨不同生物刺激剂对玉米的产量和品质方面的影响,为鲜食玉米的优质高产栽培提供技术支撑。以鲜食玉米‘钱江糯3号’为试验品种,以3种生物刺激剂(阿美滋、美基、保康灵1号)为供试药剂,设置6个处理(阿美滋1000倍液、阿美滋1500倍液、阿美滋2000倍液、美基3000倍液、保康灵1号300倍液、清水对照),研究大田常规施肥水平下药剂对‘钱江糯3号’的经济性状、产量及品质的影响。在阿美滋1500倍液喷施下,玉米的行粒数、单穗鲜重和单穗净重、产量均最高,蛋白质含量、粗纤维含量、还原糖含量、淀粉含量均居第3位;在保康灵1号300倍液喷施下,玉米的穗粗最高,单穗鲜重、单穗净重、产量均居第2位,蛋白质含量最高,脂肪含量最低,还原糖含量居第2位。阿美滋1500倍液在增加玉米产量上是最佳选择,保康灵1号300倍液则对提升玉米品质最有效果。建议生产上将阿美滋1500倍液与保康灵1号300倍液配合施用,这对鲜食玉米的增产提质效果最好。 展开更多
关键词 生物刺激剂 鲜食玉米 经济性状 产量 品质
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引入文献阅读的分析化学教学实践 被引量:4
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作者 吴缨 姚李 +1 位作者 高大明 胡坤宏 《大学化学》 CAS 2021年第8期17-20,共4页
围绕应用型高校人才培养目标,在分析化学教学中引入文献阅读的实践,对文献内容的选择、教学方法和考核方式进行了探索,此举可以帮助学生理解各种分析方法在实际生产科学研究中的应用,促进学生理论知识与实践能力的有效融合,实现学生综... 围绕应用型高校人才培养目标,在分析化学教学中引入文献阅读的实践,对文献内容的选择、教学方法和考核方式进行了探索,此举可以帮助学生理解各种分析方法在实际生产科学研究中的应用,促进学生理论知识与实践能力的有效融合,实现学生综合能力的提高。 展开更多
关键词 分析化学 文献阅读 本科生 教学改革
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