As a promising cancer treatment method,cold atmospheric plasma has received widespread attention in recent years.However,previous research has focused more on how to realize and expand the anti-cancer scope of plasma ...As a promising cancer treatment method,cold atmospheric plasma has received widespread attention in recent years.However,previous research has focused more on how to realize and expand the anti-cancer scope of plasma jet.There are also studies on the killing of small-scale cancer cells,but the effects of plasma jet on normal cells and normal cell clusters have been ignored.Therefore,we proposed a 50μm sized micro-plasma jet device,and used the device to treat melanoma cells(A-375)and human glial cells(HA1800)to evaluate their anti-cancer effects and effects on normal cells.The experimental results show that this kind of micro-plasma jet device can effectively inactivate cancer cells in a short period of time,while having little effect on normal cells.This work provides a certain experimental basis for the application offine plasma jet to clinically inactivate cancer cells.展开更多
基金supported by the National Natural Foundation of China(No.21827804,No.22103075,No.22173089)the National Key R&D Program of China(No.2021YFA0716801,No.2017YFA0303502)。
基金supported by the National Natural Science Foundation of China under Grant Number 62163009 and 61864001the Natural Science Foundation of GuangXi under Grant Number 2021JJD170019+2 种基金the Foundation of Guangxi Key Laboratory of Automatic Detecting Technology and Instruments(Guilin University of Electronic Technology)under Grant Number YQ23103Innovation Project of GuangXi Graduate Education under Grant Nos.YCSW2022277 and 2023YCXS184Guangxi Major Scientific and Technological Innovation Base(Guilin University of Electronic Technology)under Grant 231002-k.
文摘As a promising cancer treatment method,cold atmospheric plasma has received widespread attention in recent years.However,previous research has focused more on how to realize and expand the anti-cancer scope of plasma jet.There are also studies on the killing of small-scale cancer cells,but the effects of plasma jet on normal cells and normal cell clusters have been ignored.Therefore,we proposed a 50μm sized micro-plasma jet device,and used the device to treat melanoma cells(A-375)and human glial cells(HA1800)to evaluate their anti-cancer effects and effects on normal cells.The experimental results show that this kind of micro-plasma jet device can effectively inactivate cancer cells in a short period of time,while having little effect on normal cells.This work provides a certain experimental basis for the application offine plasma jet to clinically inactivate cancer cells.
