Gastric cancer is one of the leading causes of cancerrelated deaths worldwide, although the incidence has gradually decreased in many Western countries. Two main gastric cancer histotypes, intestinal and diffuse, are ...Gastric cancer is one of the leading causes of cancerrelated deaths worldwide, although the incidence has gradually decreased in many Western countries. Two main gastric cancer histotypes, intestinal and diffuse, are recognised. Although most of the described genetic alterations have been observed in both types, different genetic pathways have been hypothesized. Genetic and epigenetic events, including 1q loss of heterozygosity (LOH), microsatellite instability and hypermethylation, have mostly been reported in intestinal-type gastric carcinoma and its precursor lesions, whereas 17p LOH, mutation or loss of E-cadherin are more often implicated in the development of diffuse-type gastric cancer.In this review, we summarize the sometimes contradictory findings regarding those markers which influence the progression of gastric adenocarcinoma.展开更多
Bildung, a western cultural ideal, which fundamentally can be traced back to biblical connotations, but is also rich in Platonic elements from the history of hermeneutics, reached its culmination point by the 19th cen...Bildung, a western cultural ideal, which fundamentally can be traced back to biblical connotations, but is also rich in Platonic elements from the history of hermeneutics, reached its culmination point by the 19th century. As the vast superstructure of western erudition, it has acquired the rank of the sole discursive and epistemic normativity, which has defined not only its own system, i.e., education in its narrow sense, but also the criteria of scientific assertions. Since the basis of Bildung was formed by the variations of classical erudition changing by every era, so in the Age of Bildung the defining epistemological and methodological pattern, which determined it from a discursive, and at the same time, an epistemological point of view, was meant by classical philology. As a classical philologist Friedrich Nietzsche was among the first to point out the inseparable connection between rhetoric, interpretation, and epistemology. Nietzsche, as against the monolithic tradition of Bildung, developed a set of aspects of subversive criticism of science, so his surpassing of the nineteenth century academic philology and renewal of it as a kind of cultural hermeneutics walk hand in hand. Nietzschean philology, first and foremost, has to be adapted for revaluing its scientific statements from the aspect of art, i.e., aesthetical sensitivity, which has to be reassessed from viewpoint of effects on life as active potential. The claims of Nietzsche are so comprehensive that the notion of morality defined by Bildung, as well as the ethical system of Bildung, the sole sense of morality is questioned, and his issues are extended over the methodological basis of Bildung considered as normative. However, he does not use such a method of interpretation that, to a certain extent, would not have been known and used by the philology of the Bildung＇s scientific ideal. With the difference that the Nietzschean critical practice does not have respect for the borders defining homologous structures but, by implementing transgressive tactics, it claims the authority of these borders. In my article, I show how the Nietzschean propositions for the methodological reform of classical philology did set the stage for Nietzsche＇s later critical comments, now purely on the philosophy of science, and I analyse the multifold consequences of the concept of the Nietzschean philology as an ＂existential science,＂ which was aimed to de（con）struct the concept of Bildung.展开更多
Gas extraction is one of the main measures of control and use of gas of coal mines. At present, the design method is under the experimental period and do not satisfy the need of practice. In this paper, the theory of ...Gas extraction is one of the main measures of control and use of gas of coal mines. At present, the design method is under the experimental period and do not satisfy the need of practice. In this paper, the theory of gas extraction of coal seams based upon Darcy law was studied. Mathematical model of gas extraction of coal seams was established and two kinds of solv- ing approaches based on computer software and linear approximation were given. The rightness and the validities of the model were examined with a practical example. Results obtained can be used to determine and optimize the parameters related etc.展开更多
This paper1 reevaluates the portrayal of Mrs. Gant in William Faulkner＇s short story ＂Miss Zilphia Gant＂ （1932）. It argues that Faulkner represents her as ＂the mother as a monster＂ and looks at the features of ...This paper1 reevaluates the portrayal of Mrs. Gant in William Faulkner＇s short story ＂Miss Zilphia Gant＂ （1932）. It argues that Faulkner represents her as ＂the mother as a monster＂ and looks at the features of that representation. More specifically, the paper devotes attention to this abusive mother＇s curious masculinity, employing feminist readings from two angles. That is, on the one hand, the paper reexamines the nature of Mrs. Gant＇s unfemininity by considering the immense responsibility of child-rearing that mothers bear in modern societies. On the other hand, it attempts to locate the origin of her bodily manliness by considering the prism of images of women as evil and destabilizing that pervaded Western culture early in the twentieth century. Such approaches have revealed that making a monster of a mother requires a conspiracy taking advantage of both the inconsistencies inherent in the ideals of motherhood and the bizarre processes through which femininity itself is masculinized. In conclusion, this paper argues that Mrs. Gant＇s monstrosity is a reflection of a predicament which many women in modern times whether Faulkner＇s or our own share, that is, being expected to be a perfect mother while still being viciously castigated as sexually threatening.展开更多
This paper establishes the theoretical hypothesis of carbon intensity convergence, and through statistics to analyze and describe the whole country and the eastern and western regions with the use of mixed regression ...This paper establishes the theoretical hypothesis of carbon intensity convergence, and through statistics to analyze and describe the whole country and the eastern and western regions with the use of mixed regression model and fixed effects regression method, and test σ -convergence, absolute convergence and conditional convergence in order to have an empirical study on carbon convergence hypothesis.展开更多
文摘Gastric cancer is one of the leading causes of cancerrelated deaths worldwide, although the incidence has gradually decreased in many Western countries. Two main gastric cancer histotypes, intestinal and diffuse, are recognised. Although most of the described genetic alterations have been observed in both types, different genetic pathways have been hypothesized. Genetic and epigenetic events, including 1q loss of heterozygosity (LOH), microsatellite instability and hypermethylation, have mostly been reported in intestinal-type gastric carcinoma and its precursor lesions, whereas 17p LOH, mutation or loss of E-cadherin are more often implicated in the development of diffuse-type gastric cancer.In this review, we summarize the sometimes contradictory findings regarding those markers which influence the progression of gastric adenocarcinoma.
文摘Bildung, a western cultural ideal, which fundamentally can be traced back to biblical connotations, but is also rich in Platonic elements from the history of hermeneutics, reached its culmination point by the 19th century. As the vast superstructure of western erudition, it has acquired the rank of the sole discursive and epistemic normativity, which has defined not only its own system, i.e., education in its narrow sense, but also the criteria of scientific assertions. Since the basis of Bildung was formed by the variations of classical erudition changing by every era, so in the Age of Bildung the defining epistemological and methodological pattern, which determined it from a discursive, and at the same time, an epistemological point of view, was meant by classical philology. As a classical philologist Friedrich Nietzsche was among the first to point out the inseparable connection between rhetoric, interpretation, and epistemology. Nietzsche, as against the monolithic tradition of Bildung, developed a set of aspects of subversive criticism of science, so his surpassing of the nineteenth century academic philology and renewal of it as a kind of cultural hermeneutics walk hand in hand. Nietzschean philology, first and foremost, has to be adapted for revaluing its scientific statements from the aspect of art, i.e., aesthetical sensitivity, which has to be reassessed from viewpoint of effects on life as active potential. The claims of Nietzsche are so comprehensive that the notion of morality defined by Bildung, as well as the ethical system of Bildung, the sole sense of morality is questioned, and his issues are extended over the methodological basis of Bildung considered as normative. However, he does not use such a method of interpretation that, to a certain extent, would not have been known and used by the philology of the Bildung＇s scientific ideal. With the difference that the Nietzschean critical practice does not have respect for the borders defining homologous structures but, by implementing transgressive tactics, it claims the authority of these borders. In my article, I show how the Nietzschean propositions for the methodological reform of classical philology did set the stage for Nietzsche＇s later critical comments, now purely on the philosophy of science, and I analyse the multifold consequences of the concept of the Nietzschean philology as an ＂existential science,＂ which was aimed to de（con）struct the concept of Bildung.
文摘Gas extraction is one of the main measures of control and use of gas of coal mines. At present, the design method is under the experimental period and do not satisfy the need of practice. In this paper, the theory of gas extraction of coal seams based upon Darcy law was studied. Mathematical model of gas extraction of coal seams was established and two kinds of solv- ing approaches based on computer software and linear approximation were given. The rightness and the validities of the model were examined with a practical example. Results obtained can be used to determine and optimize the parameters related etc.
文摘This paper1 reevaluates the portrayal of Mrs. Gant in William Faulkner＇s short story ＂Miss Zilphia Gant＂ （1932）. It argues that Faulkner represents her as ＂the mother as a monster＂ and looks at the features of that representation. More specifically, the paper devotes attention to this abusive mother＇s curious masculinity, employing feminist readings from two angles. That is, on the one hand, the paper reexamines the nature of Mrs. Gant＇s unfemininity by considering the immense responsibility of child-rearing that mothers bear in modern societies. On the other hand, it attempts to locate the origin of her bodily manliness by considering the prism of images of women as evil and destabilizing that pervaded Western culture early in the twentieth century. Such approaches have revealed that making a monster of a mother requires a conspiracy taking advantage of both the inconsistencies inherent in the ideals of motherhood and the bizarre processes through which femininity itself is masculinized. In conclusion, this paper argues that Mrs. Gant＇s monstrosity is a reflection of a predicament which many women in modern times whether Faulkner＇s or our own share, that is, being expected to be a perfect mother while still being viciously castigated as sexually threatening.
文摘This paper establishes the theoretical hypothesis of carbon intensity convergence, and through statistics to analyze and describe the whole country and the eastern and western regions with the use of mixed regression model and fixed effects regression method, and test σ -convergence, absolute convergence and conditional convergence in order to have an empirical study on carbon convergence hypothesis.
