The knoevenagel condensation reaction of barbituric acid and aromatic aldehyde under ground and heated in solventless system was described. The reaction mechanism was also proposed. The structures of the products were...The knoevenagel condensation reaction of barbituric acid and aromatic aldehyde under ground and heated in solventless system was described. The reaction mechanism was also proposed. The structures of the products were identified by IR, 1H NMR, 13 C NMR and UV. 5 Alkylidene barbituric acid was the only product in the two reaction systems.展开更多
Arylidene thiazolineone derivatives are synthesized by solid state condensation of aromatic aldehydes with 2,4 thiazolidinedione or N phenylrhodanine in the presence of NaAc at 120～140 ℃ for 10 min with yields of 55...Arylidene thiazolineone derivatives are synthesized by solid state condensation of aromatic aldehydes with 2,4 thiazolidinedione or N phenylrhodanine in the presence of NaAc at 120～140 ℃ for 10 min with yields of 55%～81 2%. The effect of reaction conditions are discussed. This is a simple, time saving and environmental friendly method for the preparation of 5 arylidene thiazolineone derivatives.展开更多
The solid condensation of isopropylidene malonate with aromatic aldehydes were carried out by grinding at room temperature or heating at 110～120 ℃ to give 5 arylidene 2,2 dimethyl 1,3 dioxane 4,6 dione . Both condit...The solid condensation of isopropylidene malonate with aromatic aldehydes were carried out by grinding at room temperature or heating at 110～120 ℃ to give 5 arylidene 2,2 dimethyl 1,3 dioxane 4,6 dione . Both conditions afford the condensation high reaction activity. The yield of the product under grinding for 20 min followed by standing for 48 h at room temperature is 56%～80% and that by heating at 110～120 ℃ for 12 min is 55%～74%, respectively.展开更多
文摘The knoevenagel condensation reaction of barbituric acid and aromatic aldehyde under ground and heated in solventless system was described. The reaction mechanism was also proposed. The structures of the products were identified by IR, 1H NMR, 13 C NMR and UV. 5 Alkylidene barbituric acid was the only product in the two reaction systems.
文摘Arylidene thiazolineone derivatives are synthesized by solid state condensation of aromatic aldehydes with 2,4 thiazolidinedione or N phenylrhodanine in the presence of NaAc at 120～140 ℃ for 10 min with yields of 55%～81 2%. The effect of reaction conditions are discussed. This is a simple, time saving and environmental friendly method for the preparation of 5 arylidene thiazolineone derivatives.
文摘The solid condensation of isopropylidene malonate with aromatic aldehydes were carried out by grinding at room temperature or heating at 110～120 ℃ to give 5 arylidene 2,2 dimethyl 1,3 dioxane 4,6 dione . Both conditions afford the condensation high reaction activity. The yield of the product under grinding for 20 min followed by standing for 48 h at room temperature is 56%～80% and that by heating at 110～120 ℃ for 12 min is 55%～74%, respectively.
