许多随机试验表明减少盐的摄入可降低高血压者的血压。然而，极少考虑在各类高血压的效果。最近英国第三次和第四次全国卫生和营养调查（the third and fourth National Health and Nutrition Examination Survey）的分析提示，盐的摄...许多随机试验表明减少盐的摄入可降低高血压者的血压。然而，极少考虑在各类高血压的效果。最近英国第三次和第四次全国卫生和营养调查（the third and fourth National Health and Nutrition Examination Survey）的分析提示，盐的摄入可能与单纯收缩期或复合高血压者的血压无关。展开更多
Objective: To investigate with the use of ambulatory blood pressure (BP) monitoring whether nocturnal BP dip and nighttime BP values are different in children with untreated primary and secondary hypertension. Study d...Objective: To investigate with the use of ambulatory blood pressure (BP) monitoring whether nocturnal BP dip and nighttime BP values are different in children with untreated primary and secondary hypertension. Study design: Ambulatory BP monitoring studies from 145 children with untreated hypertension were retrospectively analyzed. Forty-five children had primary hypertension and 100 children had secondary hyperten sion. Results: Children with secondary hypertension had lower nocturnal BP dip for systolic and diastolic BP in comparison to children with primary hypertension (8% ± 5% vs 14% ± 4% for systolic and 14% ± 7% vs 22% ± 5% for diastolic BP, P < .0001 for both). Eleven percent of children with primary hypertension were classified as nondipper (BP dip < 10% ) for systolic BP and no child for diastolic BP; on the contrary, in children with secondary hypertension, 65% were nondippers for systolic and 21% for diastolic BP. Nocturnal systolic and diastolic BP loads were significantly greater in children with secondary hypertension than in those with primary hypertension. Conclusions: Reduced nocturnal BP dip and sustained nighttime BP elevation are specific markers of secondary hypertension in children with untreated hypertension. Children with blunted nocturnal BP dip or sustained nighttime hypertension should be thoroughly investigated searching for the underlying cause of hypertension.展开更多
文摘许多随机试验表明减少盐的摄入可降低高血压者的血压。然而，极少考虑在各类高血压的效果。最近英国第三次和第四次全国卫生和营养调查（the third and fourth National Health and Nutrition Examination Survey）的分析提示，盐的摄入可能与单纯收缩期或复合高血压者的血压无关。
文摘Objective: To investigate with the use of ambulatory blood pressure (BP) monitoring whether nocturnal BP dip and nighttime BP values are different in children with untreated primary and secondary hypertension. Study design: Ambulatory BP monitoring studies from 145 children with untreated hypertension were retrospectively analyzed. Forty-five children had primary hypertension and 100 children had secondary hyperten sion. Results: Children with secondary hypertension had lower nocturnal BP dip for systolic and diastolic BP in comparison to children with primary hypertension (8% ± 5% vs 14% ± 4% for systolic and 14% ± 7% vs 22% ± 5% for diastolic BP, P < .0001 for both). Eleven percent of children with primary hypertension were classified as nondipper (BP dip < 10% ) for systolic BP and no child for diastolic BP; on the contrary, in children with secondary hypertension, 65% were nondippers for systolic and 21% for diastolic BP. Nocturnal systolic and diastolic BP loads were significantly greater in children with secondary hypertension than in those with primary hypertension. Conclusions: Reduced nocturnal BP dip and sustained nighttime BP elevation are specific markers of secondary hypertension in children with untreated hypertension. Children with blunted nocturnal BP dip or sustained nighttime hypertension should be thoroughly investigated searching for the underlying cause of hypertension.
