Objective:To assess the haematological and lipid profile assays in asthmatics.Methods: Eighty asthmatic subjects were prospectively studied in a major referral centre serving the Niger Delta region of Nigeria for 12 m...Objective:To assess the haematological and lipid profile assays in asthmatics.Methods: Eighty asthmatic subjects were prospectively studied in a major referral centre serving the Niger Delta region of Nigeria for 12 months(2006-2007).Clinico-haematological and serum lipid total cholesterol(TC),triglyceride(TG),and lipoproteins concentration were analyzed after adjusting for age,cigarette smoking,alcohol ingestion,hypertension and diabetes mellitus.Results: Eighty patients(34 males and 46 females) were seen with female predominating in the various age groups(M∶F ratio,0.7∶1).Total cholesterol and low density lipoproteins-cholesterol for the asthmatics was significantly higher than the controls(P<0.000 1),while the ratio of TC∶HDL-C(high density lipoprotein-cholesterol) in asthmatics was 3.67 compared to the control value of 3.01.TC and low density lipoprotein-cholesterole(LDL-C) were significantly higher in females than the males(P<0.05).There was a combined hypertriglyceridemia(HT,>2.3mmol/L) and a significant hypercholesterolemia(HC,>5.2mmol/L) according to the Adult Treatment Panel III definition in asthmatics thereby putting them at increased risk for the development of cardiovascular disease as well as other disorders related to excess lipids.There was a significant thrombocytopenia(P<0.000 1) which may accompany allergen exposure and this persists for 24 h;that asthmatics of African descent showed a significantly increased total leucocyte count(P=0.001) similar to other studies in the Western countries.Conclusion: Hyperlipidaemia is a prevalent medical problem among asthmatics;hence screening for fasting serum lipid levels to identify those who need early intervention is recommended.展开更多
FGS was isolated and purified from laminaria japonica by enzymolysis, chromatography methods and so on. The high blood fat model was established by feeding mouse on high fat feedstuff. Compared with control group, the...FGS was isolated and purified from laminaria japonica by enzymolysis, chromatography methods and so on. The high blood fat model was established by feeding mouse on high fat feedstuff. Compared with control group, the concentration of HDL-C, the ratio of HDL-C/TC increased;while the concentration of TC, LDL-C and TG decreased in experimental groups. Conclusion: FGS was an effective serum lipid regulator and can be developed as medicine and health food.展开更多
文摘Objective:To assess the haematological and lipid profile assays in asthmatics.Methods: Eighty asthmatic subjects were prospectively studied in a major referral centre serving the Niger Delta region of Nigeria for 12 months(2006-2007).Clinico-haematological and serum lipid total cholesterol(TC),triglyceride(TG),and lipoproteins concentration were analyzed after adjusting for age,cigarette smoking,alcohol ingestion,hypertension and diabetes mellitus.Results: Eighty patients(34 males and 46 females) were seen with female predominating in the various age groups(M∶F ratio,0.7∶1).Total cholesterol and low density lipoproteins-cholesterol for the asthmatics was significantly higher than the controls(P<0.000 1),while the ratio of TC∶HDL-C(high density lipoprotein-cholesterol) in asthmatics was 3.67 compared to the control value of 3.01.TC and low density lipoprotein-cholesterole(LDL-C) were significantly higher in females than the males(P<0.05).There was a combined hypertriglyceridemia(HT,>2.3mmol/L) and a significant hypercholesterolemia(HC,>5.2mmol/L) according to the Adult Treatment Panel III definition in asthmatics thereby putting them at increased risk for the development of cardiovascular disease as well as other disorders related to excess lipids.There was a significant thrombocytopenia(P<0.000 1) which may accompany allergen exposure and this persists for 24 h;that asthmatics of African descent showed a significantly increased total leucocyte count(P=0.001) similar to other studies in the Western countries.Conclusion: Hyperlipidaemia is a prevalent medical problem among asthmatics;hence screening for fasting serum lipid levels to identify those who need early intervention is recommended.
文摘FGS was isolated and purified from laminaria japonica by enzymolysis, chromatography methods and so on. The high blood fat model was established by feeding mouse on high fat feedstuff. Compared with control group, the concentration of HDL-C, the ratio of HDL-C/TC increased;while the concentration of TC, LDL-C and TG decreased in experimental groups. Conclusion: FGS was an effective serum lipid regulator and can be developed as medicine and health food.
