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Cronkhite-Canada综合征1例
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作者 黄九香 施林林 《皮肤性病诊疗学杂志》 2024年第4期266-269,共4页
报告Cronkhite-Canada综合征1例。患者男,68岁,因腹痛、腹泻3个月就诊。皮肤科检查:头发弥漫性稀疏,额顶部明显。上下唇部、双手部、双足底可见对称性弥漫性褐色色素沉着,其上多个绿豆大小的点滴状分布的黑色斑疹,趾指甲远端2/3断裂缺如... 报告Cronkhite-Canada综合征1例。患者男,68岁,因腹痛、腹泻3个月就诊。皮肤科检查:头发弥漫性稀疏,额顶部明显。上下唇部、双手部、双足底可见对称性弥漫性褐色色素沉着,其上多个绿豆大小的点滴状分布的黑色斑疹,趾指甲远端2/3断裂缺如,甲板表面粗糙、凹凸不平无光泽。双上眼睑及小腿出现凹陷性水肿。实验室检查:贫血、低蛋白血症。电子肠镜检查:结肠多发息肉。诊断:Cronkhite-Canada综合征。给予高蛋白等营养支持治疗和对症处理。治疗后贫血及低蛋白血症明显改善,肠息肉暂无复发。目前仍在进一步随访中。 展开更多
关键词 CRONKHITE-canada综合征 色素沉着 脱发 甲营养不良 胃肠道息肉
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Cronkhite-Canada综合征合并无症状新型冠状病毒感染一例 被引量:1
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作者 张宁 杨晨皓 +5 位作者 周良瑞 孙晓红 刘晓红 康琳 李骥 李海龙 《协和医学杂志》 CSCD 北大核心 2024年第2期406-412,共7页
本文报道Cronkhite⁃Canada综合征合并无症状新型冠状病毒感染1例。该患者临床表现为食欲减退,毛发及指甲脱落,皮肤色素沉着。内镜检查见胃、十二指肠及结肠黏膜呈弥漫性、大小不一、密集分布的息肉样改变。病程中检出新型冠状病毒核酸... 本文报道Cronkhite⁃Canada综合征合并无症状新型冠状病毒感染1例。该患者临床表现为食欲减退,毛发及指甲脱落,皮肤色素沉着。内镜检查见胃、十二指肠及结肠黏膜呈弥漫性、大小不一、密集分布的息肉样改变。病程中检出新型冠状病毒核酸阳性。经中等剂量泼尼松治疗后,患者毛发恢复生长,皮肤色素沉着减退。本文总结该患者的诊疗经过并结合文献复习,以期提升临床医生对该病的认知。 展开更多
关键词 Cronkhite⁃canada综合征 新型冠状病毒感染 治疗
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Severe Global Environmental Issues Caused by Canada’s Record-Breaking Wildfires in 2023 被引量:4
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作者 Zhe WANG Zifa WANG +8 位作者 Zhiyin ZOU Xueshun CHEN Huangjian WU Wending WANG Hang SU Fang LI Wenru XU Zhihua LIU Jiaojun ZHU 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第4期565-571,共7页
Due to the record-breaking wildfires that occurred in Canada in 2023,unprecedented quantities of air pollutants and greenhouse gases were released into the atmosphere.The wildfires had emitted more than 1.3 Pg CO_(2)a... Due to the record-breaking wildfires that occurred in Canada in 2023,unprecedented quantities of air pollutants and greenhouse gases were released into the atmosphere.The wildfires had emitted more than 1.3 Pg CO_(2)and 0.14 Pg CO_(2)equivalent of other greenhouse gases(GHG)including CH4 and N_(2)O as of 31 August.The wildfire-related GHG emissions constituted more than doubled Canada’s planned cumulative anthropogenic emissions reductions in 10 years,which represents a significant challenge to climate mitigation efforts.The model simulations showed that the Canadian wildfires impacted not only the local air quality but also that of most areas in the northern hemisphere due to long-range transport,causing severe PM_(2.5)pollution in the northeastern United States and increasing daily mean PM_(2.5)concentration in northwestern China by up to 2μg m-3.The observed maximum daily mean PM_(2.5)concentration in New York City reached 148.3μg m-3,which was their worst air quality in more than 50 years,nearly 10 times that of the air quality guideline(i.e.,15μg m-3)issued by the World Health Organization(WHO).Aside from the direct emissions from forest fires,the peat fires beneath the surface might smolder for several months or even longer and release substantial amounts of CO_(2).The substantial amounts of greenhouse gases from forest and peat fires might contribute to the positive feedback to the climate,potentially accelerating global warming.To better understand the comprehensive environmental effects of wildfires and their interactions with the climate system,more detailed research based on advanced observations and Earth System Models is essential. 展开更多
关键词 canada forest fire greenhouse gases PM_(2.5) transboundary air pollution
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Cronkhite-Canada综合征2例并文献复习
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作者 张泽雨 康其乐 +4 位作者 郭驰伟 王农荣 谢桂生 付小君 斯轶凡 《南昌大学学报(医学版)》 2024年第2期98-104,共7页
目的探讨Cronkhite-Canada综合征(Cronkhite-Canada syndrome,CCS)的临床特征、治疗方法及预后。方法收集南昌大学第四附属医院消化内科收治的2例CCS患者的临床资料,结合相关文献,对其诊疗、转归以及长期消化内镜的随访资料进行分析。结... 目的探讨Cronkhite-Canada综合征(Cronkhite-Canada syndrome,CCS)的临床特征、治疗方法及预后。方法收集南昌大学第四附属医院消化内科收治的2例CCS患者的临床资料,结合相关文献,对其诊疗、转归以及长期消化内镜的随访资料进行分析。结果2例患者均以胃息肉病变为突出表现。例1于2013年5月确诊CCS并结肠癌,予外科手术、内镜下部分息肉切除术及营养支持治疗后,患者营养状况明显好转,确诊后2年间进行6次胃镜随访,2015年4月确诊胃窦恶性溃疡,2017年7月死亡。例2于2019年6月入院时诊断不明,结合患者其他症状及体征,诊断为CCS,采用激素治疗效果不佳,后因病情进展行全胃切除,术后随访2年,目前病情稳定。结论CCS病情多呈进行性加重,具有恶变趋势,治疗上以糖皮质激素为主,必要时可考虑切除严重病变部位,长期消化内镜下随访有助于诊断疾病及发现早期癌变。 展开更多
关键词 CRONKHITE-canada综合征 外胚层改变 胃镜随访 病例报告
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Impact of Reservoir Heterogeneity on Bitumen Content in the Mackay River Oil Sands,Athabasca(Canada)
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作者 YANG Xiaofa YU Diyun +6 位作者 WU Suwei REN Junhao CHENG Dingsheng HUANG Jixin YANG Chengyu MA Guoqing LI Meijun 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2024年第5期1285-1300,共16页
The Lower Cretaceous Manville Group of Upper Mc Murray Formation is one of the main bitumen reservoirs in Athabasca.In this study,the relationship between reservoirs heterogeneity and bitumen geochemical characteristi... The Lower Cretaceous Manville Group of Upper Mc Murray Formation is one of the main bitumen reservoirs in Athabasca.In this study,the relationship between reservoirs heterogeneity and bitumen geochemical characteristics were analyzed through core and microscopic observation,lab analysis,petrophysics and logging data.Based on the sedimentology framework,the formation environment of high-quality oil sand reservoirs and their significance for development were discussed.The results indicate that four types lithofacies were recognized in the Upper Mc Murray Formation based on their depositional characteristics.Each lithofacies reservoirs has unique physical properties,and is subject to varying degrees of degradation,resulting in diversity of bitumen content and geochemical composition.The tidal bar(TB)or tidal channel(TC)facies reservoir have excellent physical properties,which are evaluated as gas or water intervals due to strong degradation.The reservoir of sand bar(SB)facies was evaluated as oil intervals,due to its poor physical properties and weak degradation.The reservoir of mixed flat(MF)facies is composed of sand intercalated with laminated shale,which is evaluated as poor oil intervals due to its poor connectivity.The shale content in oil sand reservoir is very important for the reservoir physical properties and bitumen degradation degree.In the context of regional biodegradation,oil sand reservoirs with good physical properties will suffer from strong degradation,while oil sand reservoirs with relatively poor physical properties are more conducive to the bitumen preservation. 展开更多
关键词 oil sands reservoir heterogeneity geochemical characteristics bitumen content Upper Mc Murray Formation canada
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Study of Canada’s Economic System from a System Thinking Perspective
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作者 Wei Zhang Yuejun Cui 《Proceedings of Business and Economic Studies》 2024年第3期179-187,共9页
This article analyzes Canada’s economic system from a systems thinking perspective.The content includes patterns of public choice(party system and power distribution),organizational framework of decision-making arran... This article analyzes Canada’s economic system from a systems thinking perspective.The content includes patterns of public choice(party system and power distribution),organizational framework of decision-making arrangements,information provision and coordination mechanisms,property rights system,incentive system,and welfare system.Canada’s economic system significantly influences the development of the Canadian economy,and its economic system arrangements hold reference significance for other developed and developing countries. 展开更多
关键词 canada Economic system Party system Power distribution Property rights system
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Cronkhite-Canada综合征9例临床分析
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作者 李松霏 丁士刚 《胃肠病学》 北大核心 2023年第12期717-721,共5页
背景:Cronkhite-Canada综合征(CCS)是一种病因不明的罕见非遗传性疾病,目前其诊断和治疗仍面临挑战。目的:总结中国人CCS的临床特征、治疗和转归,以提高临床医师对该病的认知。方法:回顾性分析北京大学第三医院2012—2022年间收治的CCS... 背景:Cronkhite-Canada综合征(CCS)是一种病因不明的罕见非遗传性疾病,目前其诊断和治疗仍面临挑战。目的:总结中国人CCS的临床特征、治疗和转归,以提高临床医师对该病的认知。方法:回顾性分析北京大学第三医院2012—2022年间收治的CCS病例。结果:研究共纳入9例CCS患者,男女比例为1.25∶1,确诊时平均年龄63.89岁。所有患者均表现为胃肠道息肉病、非特异性消化道症状以及至少一项外胚层表现,粪隐血试验均阳性,缺铁性贫血、低白蛋白血症、IgE升高常见。组织学表现为增生性息肉或腺瘤性息肉,嗜酸性粒细胞浸润常见。患者存在严重骨质疏松和骨折、小肠细菌过度生长、哮喘、膜性肾病、结节性甲状腺肿和腹膜后纤维化、焦虑状态等合并症。多数患者激素治疗有较好效果,但激素减量或停用后疾病可反复。1例患者尝试应用硫唑嘌呤治疗,但效果欠佳。结论:CCS是一种免疫相关疾病,感染、过敏、遗传因素、肠道微生态等在CCS发病中的作用有待进一步研究。激素是目前CCS的主要治疗手段,存在激素抵抗或激素治疗禁忌的患者治疗仍面临挑战。 展开更多
关键词 CRONKHITE-canada综合征 胃肠道息肉病 糖皮质激素
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CT小肠造影诊断Cronkhite-Canada综合征临床案例分析
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作者 赵雪松 缪飞 +4 位作者 孙菁 董屹寒 张欢 严福华 丁蓓 《CT理论与应用研究(中英文)》 2023年第2期263-270,共8页
Cronkhite-Canada综合征(CCS)是一组以胃肠道弥漫性息肉和外胚层变化为特征的综合征,其临床表现主要为慢性腹泻和吸收不良,由于发病率罕见,早期发现和诊断对医生来说是一个挑战。本文报告1例CCS病例,58岁男性,临床表现为慢性水样腹泻、... Cronkhite-Canada综合征(CCS)是一组以胃肠道弥漫性息肉和外胚层变化为特征的综合征,其临床表现主要为慢性腹泻和吸收不良,由于发病率罕见,早期发现和诊断对医生来说是一个挑战。本文报告1例CCS病例,58岁男性,临床表现为慢性水样腹泻、便血、体重减轻和皮肤变化,包括指甲营养不良和色素沉着;实验室检查结果提示贫血和低蛋白血症;CT小肠造影检查发现全消化道黏膜息肉样增生,高度怀疑CCS,随后行内镜检查证实了该诊断。患者经治疗后,症状明显好转,在近1年的随访中,CT小肠造影和内镜检查均提示明显缓解。本文对该疾病进行文献综述,旨在总结其CT小肠造影表现,以提高临床医生对本病的认识,为CCS的早期诊断提供一定的思路。 展开更多
关键词 CT小肠造影 息肉-色素沉着-脱发-指(趾)甲营养不良综合征 诊断
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Emergency department presentation changes due to the coronavirus disease pandemic in Nova Scotia,Canada
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作者 Tara Dahn Patrick T.Fok +9 位作者 Hana Wiemer Daniel J.Dutton Valancy Cole David Lewis Tong Liu Keith R.Brunt Robert Hanlon Jacqueline Fraser Chris Vaillancourt Paul Atkinson 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2023年第1期62-64,共3页
Multiple studies have reported decreased emergency department(ED)patient volumes during the coronavirus disease(COVID-19)pandemic,[1-6]including areas most affected by the virus.[7]Most existing studies have investiga... Multiple studies have reported decreased emergency department(ED)patient volumes during the coronavirus disease(COVID-19)pandemic,[1-6]including areas most affected by the virus.[7]Most existing studies have investigated general trends in ED presentations and have not examined the impact of COVID-19 on different types of EDs,specific ED patient groups,or illness presentations. 展开更多
关键词 canada DEPARTMENT PATIENT
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Comprehensive treatment and a rare presentation of Cronkhite–Canada syndrome: Two case reports and review of literature
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作者 Yan-Qing Lv Mei-Lan Wang +1 位作者 Tong-Yu Tang Yu-Qin Li 《World Journal of Gastrointestinal Surgery》 SCIE 2023年第11期2646-2656,共11页
BACKGROUND Cronkhite–Canada syndrome(CCS)is a rare sporadic polyposis syndrome that presents with gastrointestinal and ectodermal symptoms in addition to nutritional deficiencies.CCS combined with hypothyroidism is a... BACKGROUND Cronkhite–Canada syndrome(CCS)is a rare sporadic polyposis syndrome that presents with gastrointestinal and ectodermal symptoms in addition to nutritional deficiencies.CCS combined with hypothyroidism is an even rarer condition,with no standard treatment guidelines.CASE SUMMARY The present study described 2 patients with CCS:A 67-year-old woman with concomitant hypothyroidism and 68-year-old man treated with endoscopic mucosal resection(EMR).Both patients had multiple gastrointestinal symptoms and ectodermal changes,along with multiple gastrointestinal polyps.Microscopic examination showed that the mucosa in both patients was hyperemic and edematous,with pathologic examination showing distorted,atrophic,and dilated glands.Patient 1 had concomitant hypothyroidism and was treated with levothyroxine.Due to her self-reduction of hormone dose,her disease relapsed.Patient 2 underwent EMR,but refused further hormonal or biological treatments.Subsequently,he was treated with an oral Chinese medical preparation.CONCLUSION Pharmacotherapy can induce and maintain remission in CCS patients,with adjuvant EMR,long-term follow-up,and endoscopic surveillance being necessary.Case 1:Based on the aforementioned findings,Patient 1 was diagnosed with CCS and hypothyroidism.Case 2:Based on the aforementioned findings,Patient 2 was diagnosed with CCS. 展开更多
关键词 Cronkhite–canada syndrome Clinical features Gastrointestinal polyps HYPOTHYROIDISM Case report
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The Logistics of Production and Supply of Ag Pellets for Industrial Applications in Canada
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作者 Shahabaddine Sokhansanj Mahmood Ebadian +1 位作者 Hamid Rezaei Fahimeh Yazdanpanah 《Journal of Sustainable Bioenergy Systems》 CAS 2023年第1期40-55,共16页
In this work we analyze the supply of biomass from field to an in-land or port destination. The biomass is pelletized to increase its bulk density to extend its storage period and for ease of its transport. The pellet... In this work we analyze the supply of biomass from field to an in-land or port destination. The biomass is pelletized to increase its bulk density to extend its storage period and for ease of its transport. The pellet may be used for conversion to chemicals and animal bedding or for straight combustion. We analyzed supply chain in Saskatchewan where there are plenty of crop residues but widely dispersed and harvest seasons are short. We envisioned that the farmer collects bales from field and transports the bales to farmstead during the harvest season. The bales are then processed into pellets using small scale pellet equipment. A custom operator with expertise in pelletization may engage in handling and densifying the biomass. The business case for the mobile mill will be similar to the well established custom grain and forage harvesting operations. The pellets are stored in hopper bottom grain bins at the farmstead. From this point, the handling of pellets would be similar to the handling and marketing of grain. The farmer trucks a specified volume of pellets from farmstead to the nearest elevator where the pellets are transferred to larger bins or silos. Pellets are extracted from silos and loaded onto the rail cars. The Canadian freight rail companies (mainly CN) currently transport over 3 million dry tonne (dt) of wood pellets in rail cars. The pellets are hauled to marine ports on the West Coast or East Coast for export. The cost of delivering ag pellets to biorefinery or to the shipping port is $86.09/dt. This cost does not include the equivalent value of removing biomass from the farm (e.g. fertilizer replacement) and return on investment. The GHG emissions to produce and transport ag pellets add up to 185.9 kg of CO<sub>2</sub> per dt of biomass. The cost of producing pellets without drying feedstock is $35.05/dt and the corresponding GHG for palletization amounts $146.30/dt. 展开更多
关键词 canada PELLETS Ag Pellets Supply Chain LOGISTICS Cost GHG Emissions INFRASTRUCTURE
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12例Cronkhite Canada综合征患者临床及病理特点 被引量:21
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作者 刘颖娴 吴东 +6 位作者 费贵军 孙钢 钱家鸣 蔡建芳 樊晓红 李亚建 罗妍 《基础医学与临床》 CSCD 北大核心 2012年第11期1349-1352,共4页
目的分析北京协和医院CCS患者流行病学及临床病理特点、治疗策略及预后。方法回顾性分析,非参数Spearman相关分析判断各治疗方法的短期及远期疗效。结果 12例CCS患者均存在上消化道和下消化道息肉,以及至少1项外胚层异常。1/3患者尿蛋... 目的分析北京协和医院CCS患者流行病学及临床病理特点、治疗策略及预后。方法回顾性分析,非参数Spearman相关分析判断各治疗方法的短期及远期疗效。结果 12例CCS患者均存在上消化道和下消化道息肉,以及至少1项外胚层异常。1/3患者尿蛋白阳性,1例合并肾病综合征。若联合腹痛、腹泻及便潜血阳性3项指标,则灵敏度为100%。胃镜下可见多发黏膜下黑褐色素斑,息肉病理类型以增生性息肉及腺管状腺瘤最常见。平均随访44.7月,存活率100%;10例在初始或后续治疗中加用糖皮质激素,均获不同程度缓解。糖皮质激素停药后复发者再次使用仍然有效。泼尼松≥40 mg/d较≤40 mg/d预后更佳(n=10,r=-0.655,P<0.05);单用氨基水杨酸制剂、胃黏膜保护剂、肠道益生菌、息肉电切术及肠内外营养支持均无明显疗效;氨基水杨酸制剂与较差预后相关(r=0.598,P<0.05)。结论 CCS患者可见黏膜下色素沉着及尿蛋白阳性,糖皮质激素为基础的综合治疗临床缓解率较高,提示其发病机制可能有免疫因素参与。 展开更多
关键词 CRONKHITE canada综合征 胃肠道息肉 泼尼松 免疫
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Cronkhite-Canada综合征2例报告并国内外文献评价 被引量:9
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作者 贾岩 孙刚 +1 位作者 郭明洲 杨云生 《胃肠病学和肝病学杂志》 CAS 2009年第7期632-636,共5页
目的总结Cronkhite-Canada综合征(CCS)的临床表现、消化道息肉特点、病理改变及诊断治疗,以提高临床医生对本病的认识。方法对我院诊断明确的2例CCS病例及1990年以来72篇文献报告的31例病例的临床资料回顾性研究。结果符合CCS诊断标准... 目的总结Cronkhite-Canada综合征(CCS)的临床表现、消化道息肉特点、病理改变及诊断治疗,以提高临床医生对本病的认识。方法对我院诊断明确的2例CCS病例及1990年以来72篇文献报告的31例病例的临床资料回顾性研究。结果符合CCS诊断标准的入组病例33例,男20例,女13例;年龄17~77岁,中位年龄51岁。临床表现为脱发、指(趾)甲改变、皮肤色素沉着、腹部不适及低蛋白血症。全部患者均有消化道多发息肉,累及胃、小肠、大肠。息肉病理无特异性,其中8例癌变。治疗方法包括激素治疗17例,内镜下息肉摘除2例,因癌变、消化道梗阻及蛋白丢失性肠病手术11例(3例同时激素治疗)和其他治疗6例,其中1年内激素治疗有效14例,最长1例随访7年无复发。结论Cronkhite-Canada综合征(CCS)是以消化道多发息肉伴外胚层改变为主要临床特点的综合征,诊断较困难,激素治疗能改善症状,长期疗效仍待进一步研究。 展开更多
关键词 Cronkhite—canada综合征(CCS) 胃肠道息肉病 息肉 激素
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Cronkhite-Canada综合征43例临床分析 被引量:10
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作者 李曼 朱明欣 黄浩 《中国现代医学杂志》 CAS CSCD 北大核心 2010年第18期2806-2808,共3页
目的分析Cronkhite-Canada综合征(CCS)的临床特点。方法报告该院收治的1例CCS患者,并检索1985年1月~2008年12月国内42例CCS患者的临床资料进行临床分析。结果国内43例CCS患者以外胚层变化、胃肠道多发性息肉为主要临床特点,2例患者合... 目的分析Cronkhite-Canada综合征(CCS)的临床特点。方法报告该院收治的1例CCS患者,并检索1985年1月~2008年12月国内42例CCS患者的临床资料进行临床分析。结果国内43例CCS患者以外胚层变化、胃肠道多发性息肉为主要临床特点,2例患者合并胃肠道肿瘤。19例患者经综合治疗症状不同程度缓解,20例随访患者平均生存时间为15个月。结论 CCS发病率极低,本病的确诊有赖于内镜及组织学检查,目前国内外暂无特异性治疗方案。本病预后不佳,半数患者确诊后2年内死亡。 展开更多
关键词 CRONKHITE-canada综合征 胃肠道息肉 临床分析
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罕见的息肉病-Cronkhite-Canada综合征 被引量:10
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作者 陈鑫 李变霞 +4 位作者 朱兰平 马双 赵经文 仲威龙 王邦茂 《世界华人消化杂志》 CAS 2019年第16期977-983,共7页
Cronkhite-Canada综合征(Cronkhite-Canadasyndrome,CCS)是一组以胃肠道弥漫性息肉、指(趾)甲营养不良、脱发、皮肤色素沉着、腹泻、体重减轻和味觉障碍等为表现的非遗传性罕见病.多数CCS临床预后不良,常合并危及生命的严重并发症.目前... Cronkhite-Canada综合征(Cronkhite-Canadasyndrome,CCS)是一组以胃肠道弥漫性息肉、指(趾)甲营养不良、脱发、皮肤色素沉着、腹泻、体重减轻和味觉障碍等为表现的非遗传性罕见病.多数CCS临床预后不良,常合并危及生命的严重并发症.目前关于CCS疾病的病因、发病机制及合理的治疗方案仍处于探索阶段.本文通过综述CCS目前常见病因、临床表现、内镜特点以及治疗方案,旨在提高临床工作中对CCS认识水平的同时并探索其病因及最佳的治疗策略. 展开更多
关键词 CRONKHITE-canada综合征 自身免疫 IGG4 幽门螺杆菌 肠道菌群
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Cronkhite-Canada综合征1例报道及现况分析 被引量:3
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作者 陈慧群 戴林 +1 位作者 李爱萍 刘云 《胃肠病学和肝病学杂志》 CAS 2013年第5期442-442,445,共2页
Cronkhite-Canada综合征罕见,发病机制不清,治疗经验缺乏,内镜检查是确诊的主要手段。现报道我院近期收治Cronkhite-Canada综合征病例1例。
关键词 Cronkhite—canada综合征
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Cronkhite-Canada综合征1例临床病理分析 被引量:3
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作者 高汉青 韩静 +1 位作者 孙淑珍 马怡晖 《胃肠病学和肝病学杂志》 CAS 2018年第4期452-454,共3页
Cronkhite-Canada综合征(Cronkhite-Canada syndrome,CCS)是一种罕见的非遗传性疾病,以外胚层异常伴弥漫性息肉病为特征。现报道1例CCS。
关键词 CRONKHITE-canada综合征 砷中毒 消化内镜 病理
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Cronkhite-Canada综合征 被引量:3
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作者 汪盛 蒋献 +1 位作者 张敏 李薇 《临床皮肤科杂志》 CAS CSCD 北大核心 2008年第5期293-296,共4页
报告1例Cronkhite-Canada综合征。患者男,36岁。味觉减退、腹泻1个月余,面部、四肢末端皮肤变黑20d,脱发10d入院。皮肤科检查:面部、四肢末端色素沉着,指(趾)甲变薄脆裂,普秃。内镜检查发现全肠道息肉。出院2个月后症状自行缓解。1年后... 报告1例Cronkhite-Canada综合征。患者男,36岁。味觉减退、腹泻1个月余,面部、四肢末端皮肤变黑20d,脱发10d入院。皮肤科检查:面部、四肢末端色素沉着,指(趾)甲变薄脆裂,普秃。内镜检查发现全肠道息肉。出院2个月后症状自行缓解。1年后因肠道息肉增大行右半结肠切除术。 展开更多
关键词 CRONKHITE-canada综合征
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Cronkhite-Canada综合征1例 被引量:1
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作者 姜娜 于亚男 +4 位作者 丁雪丽 田字彬 杨林 荆雪 江月萍 《世界华人消化杂志》 CAS 2018年第28期1672-1676,共5页
Cronkhite-Canada综合征(Cronkhite-Canada’s syndrome, CCS)是临床罕见病,病因及发病机制尚不明确,该病以胃肠道多发息肉及外胚层两大症候群为主,临床表现以腹泻为主,全消化道多发息肉,伴有皮肤色素沉着、毛发脱落、指(趾)甲萎缩脱落... Cronkhite-Canada综合征(Cronkhite-Canada’s syndrome, CCS)是临床罕见病,病因及发病机制尚不明确,该病以胃肠道多发息肉及外胚层两大症候群为主,临床表现以腹泻为主,全消化道多发息肉,伴有皮肤色素沉着、毛发脱落、指(趾)甲萎缩脱落等.预后较差,本文报道1例CCS患者并对62篇国内文献进行回顾性分析. 展开更多
关键词 CRONKHITE-canada综合征 胃肠道息肉 外胚层改变 治疗
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Cronkhite-Canada综合征2例 被引量:1
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作者 张衍国 胡新红 +1 位作者 王欢 屈慧明 《临床皮肤科杂志》 CAS CSCD 北大核心 2012年第8期499-500,共2页
例1.男,29岁。因上腹胀、恶心、呕吐间断性发作3个月于2011年3月6日入院。患者于3个月前上腹饱胀不适,进食后明显,伴有恶心、呕吐,呕吐物为胃内容物,无腹痛、腹泻。食欲渐减退,乏力消瘦。行胃镜检查示:反流性食管炎、胃癌。组... 例1.男,29岁。因上腹胀、恶心、呕吐间断性发作3个月于2011年3月6日入院。患者于3个月前上腹饱胀不适,进食后明显,伴有恶心、呕吐,呕吐物为胃内容物,无腹痛、腹泻。食欲渐减退,乏力消瘦。行胃镜检查示:反流性食管炎、胃癌。组织病理示:(胃窦)黏膜组织慢性炎症伴炎性渗出及坏死,部分腺上皮细胞中、重度不典型增生,局部少数细胞癌变。 展开更多
关键词 Cronkhite—canada综合征
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