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Headedness in Yorǘhbá: An Examination of the Deviant Value of Determiner Phrase
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作者 Issa O. Sanusi 《Sino-US English Teaching》 2014年第1期59-65,共7页
The issue of "headedness" is a product of Chomsky's (1988) notion of UG (Universal Grammar) that led to the development of a framework known as P&P (Principles and Parameters) theory. It is this theory we ha... The issue of "headedness" is a product of Chomsky's (1988) notion of UG (Universal Grammar) that led to the development of a framework known as P&P (Principles and Parameters) theory. It is this theory we have adopted for our analysis in this paper. The purpose of this paper is to examine the inconsistency in the value of Head Parameter with reference to the value of DP (determiner phrase) in Yorfib^i. As a native speaker of Yorfib~, the author has adopted an introspective method of data collection and used the intuitive knowledge of other native speakers of the language for necessary clarifications. Despite the fact that English and Yorfib~ are both head-initial, the structure of the NPs (noun phrases) in English shows that the head noun is always pre-modified, making the NP "head-final"--a violation of the value of Head Parameter in the language. This necessitated the need for Abney's (1987) DP hypothesis; in which the determiner heads its own phrase, thereby making a NP in English head-initial. This solves the problem of Head Parameter in English. However, since nouns in Yor/lb^i are post-modified, adopting "DP-analysis" will automatically produce head-final--a violation of the value of Head Parameter in the language. Given the inconsistency in the specification of head-complement order among the noun phrases in English and Yorfib~, this paper proposes to set a parameter for SVO (Subject-Verb-Object) languages with pre-modification (like English) to adopt "DP-analysis", and those with post-modification (like Yorfib^t) to adopt "NP-analysis". This will ensure "head-initial" value for the two categories of SVO languages 展开更多
关键词 headedness pre-modification post-modification DP-analysis NP-analysis English Yoruba
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Promoting People-to-People Bond among Countries along the Routes of the Belt and Road——Sidelights of CAFIU Delegation's Visit to Sri Lanka,Brunei and ROK Headed by Vice-President Zhang Baowen
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作者 Wang Xiaoyi 《International Understanding》 2015年第4期14-17,共4页
At the invitation of Sri Lanka-China Friendship Association(SLCFA),Brunei-China Friendship Association(BCFA)and National Strategy Institute of the ROK(NSI),Mr.Zhang Baowen,Vice-Chairman of NPC Standing Committee,Chair... At the invitation of Sri Lanka-China Friendship Association(SLCFA),Brunei-China Friendship Association(BCFA)and National Strategy Institute of the ROK(NSI),Mr.Zhang Baowen,Vice-Chairman of NPC Standing Committee,Chairman of the Central Committee of China Democratic League and 展开更多
关键词 LEAGUE Chairman INVITATION cooperation Standing exchanges exhibition DELEGATION headed Southeast
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Secretary-General Ni Jian Headed a Delegation to Visit ROK, Japan and Sri Lanka
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作者 Wang Lin Ma Jingjing 《International Understanding》 2013年第2期16-17,14-15,共4页
At the invitation of National Strategy Institute of ROK (NSI), Japan&China Technological Youth Interchange Society and Sri Lanka-China Friendship Association (SLCFA), CAFIU’s Secretary-General Ni Jian headed a fi... At the invitation of National Strategy Institute of ROK (NSI), Japan&China Technological Youth Interchange Society and Sri Lanka-China Friendship Association (SLCFA), CAFIU’s Secretary-General Ni Jian headed a five-member delegation to visit the three countries from March 24 to April 2. 展开更多
关键词 Secretary-General Ni Jian headed a Delegation to Visit ROK Japan and Sri Lanka NI
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Enhancing Understanding and Promoting Cooperation──a report on the visit to Algeria and Iran headed by NPC Vice-Chairman Jiang Zhenghua
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《International Understanding》 2001年第2期14-16,共3页
关键词 Enhancing Understanding and Promoting Cooperation a report on the visit to Algeria and Iran headed by NPC Vice-Chairman Jiang Zhenghua NPC
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President Zhou Tienong Headed a Delegation to Visit Hungary and Denmark
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作者 Ma Jingjing 《International Understanding》 2013年第3期37-39,共3页
At the invitation of the"World Bridge"Foundation of Hungary and the Danish-Chinese Business Forum,Mr.Zhou Tienong,ViceChairman of the Standing Committee of the 11th National People’s Congress and CAFIU’s P... At the invitation of the"World Bridge"Foundation of Hungary and the Danish-Chinese Business Forum,Mr.Zhou Tienong,ViceChairman of the Standing Committee of the 11th National People’s Congress and CAFIU’s President headed a CAFIU delegation to visit Hungary and Denmark from June 4 to 13,2013. 展开更多
关键词 World President Zhou Tienong headed a Delegation to Visit Hungary and Denmark
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Strengthen Understanding and Promote Cooperation——Highlights of Visit to Yugoslavia by Delegation Headed by Vice-President Yu Wen by Cao Rongfei
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《International Understanding》 1998年第Z1期4-5,共2页
InlateJune1998,a6memberCAFIUdelegationheadedbyVicePresidentYuWenpaidagoodwilvisittotheFederalRepublicofY... InlateJune1998,a6memberCAFIUdelegationheadedbyVicePresidentYuWenpaidagoodwilvisittotheFederalRepublicofYugoslavia.Thehost... 展开更多
关键词 YUGOSLAVIA DELEGATION headed to VISIT CAO
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Tan Zhiqiang Headed an Investigation Delegation to Fujian Province
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作者 Ren Yan 《China Textile》 2009年第5期14-15,共2页
On the invitation of the Straits Textile & Clothing Fair (STCF) committee of Shishi City,Fujian
关键词 OFFICE Tan Zhiqiang headed an Investigation Delegation to Fujian Province CPC
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Actively Promoting Regional Space Cooperation——Vice Administrator, Loan Enjie headed a delegation to attend the Second Asia-Pacific Conference on Multilateral Cooperation in Space Technology and Applications
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作者 Zhang Lihui 《Aerospace China》 1995年第1期14-15,共2页
A Chinese delegation of 24 persons headed by Mr. Luan Enjie, Vice Administrator of China National Space Administration (CNSA) attended the Second Asia-Pacific Conference on Multilateral Cooperation in Space Technology... A Chinese delegation of 24 persons headed by Mr. Luan Enjie, Vice Administrator of China National Space Administration (CNSA) attended the Second Asia-Pacific Conference on Multilateral Cooperation in Space Technology and Applications held at Islamabad, the Capital of Pakistan from April 22 to 26, 1995. Following the First AsiaPacific Workshop held in Beijing in December, 1992, and the First Asia-Pacific Conference on Multilateral Cooperation in 展开更多
关键词 Asia Loan Enjie headed a delegation to attend the Second Asia-Pacific Conference on Multilateral Cooperation in Space Technology and Applications Vice Administrator Actively Promoting Regional Space Cooperation
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Influence of surface cracking,anchor head profile,and anchor head size on cast-in headed anchors in geopolymer concrete
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作者 Trijon KARMOKAR Alireza MOYHEDDIN 《Frontiers of Structural and Civil Engineering》 SCIE EI CSCD 2023年第8期1163-1187,共25页
In this study,the concrete cone capacity,concrete cone angle,and load–displacement response of cast-in headed anchors in geopolymer concrete are explored using numerical analyses.The concrete damaged plasticity(CDP)m... In this study,the concrete cone capacity,concrete cone angle,and load–displacement response of cast-in headed anchors in geopolymer concrete are explored using numerical analyses.The concrete damaged plasticity(CDP)model in ABAQUS is used to simulate the behavior of concrete substrates.The tensile behavior of anchors in geopolymer concrete is compared with that in normal concrete as well as that predicted by the linear fracture mechanics(LFM)and concrete capacity design(CCD)models.The results show that the capacity of the anchors in geopolymer concrete is 30%–40%lower than that in normal concrete.The results also indicate that the CCD model overestimates the capacity of the anchors in geopolymer concrete,whereas the LFM model provides a much more conservative prediction.The extent of the difference between the predictions by the numerical analysis and those of the above prediction models depends on the effective embedment depth of the anchor and the anchor head size.The influence of concrete surface cracking on the capacity of the anchor is shown to depend on the location of the crack and the effective embedment depth.The influence of the anchor head profile on the tensile capacity of the anchors is found to be insignificant. 展开更多
关键词 cast-in anchor concrete cone capacity geopolymer concrete head size surface crack anchor profile
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基于改进YOLOv8的道路病害视觉识别算法
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作者 张强 杜海强 +1 位作者 赵伟康 崔冬 《现代电子技术》 北大核心 2024年第23期119-124,共6页
道路病害检测对于确保道路的安全性和可持续性至关重要,对城市和社会的发展具有积极作用。为提高目前道路病害检测模型的性能,文中提出一种基于改进YOLOv8的道路病害检测算法。设计一种新型高效的特征融合模块(DWS),提高模型获取特征信... 道路病害检测对于确保道路的安全性和可持续性至关重要,对城市和社会的发展具有积极作用。为提高目前道路病害检测模型的性能,文中提出一种基于改进YOLOv8的道路病害检测算法。设计一种新型高效的特征融合模块(DWS),提高模型获取特征信息和全局上下文信息的能力;提出将ECABlock、LeakyReLU激活函数与卷积相结合的新模块ELConv来提高深层网络对目标的定位能力;另外,使用Dynamic Head检测头替换原始YOLOv8的头部,结合尺度、空间和任务三种注意力机制提升模型头部表征能力;最后,采用WIoU损失函数代替原损失函数来改善边界框精确度和匹配度。相比基线模型,改进模型在road damage detection数据集和RDD2022_Japan数据集上都得到了有效的验证,表明改进模型满足当下道路病害检测的需求,展示了高灵活性、准确性和效率。 展开更多
关键词 道路病害检测 深度学习 YOLOv8 特征融合 激活函数 Dynamic Head WIoU损失函数
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面向热轧带钢表面缺陷检测的YOLOv5算法优化分析
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作者 马冬梅 朱佳浩 《制造技术与机床》 北大核心 2024年第6期153-160,共8页
单阶段目标检测网络YOLOv5在处理热轧带钢表面缺陷的特征提取与感受特征融合时存在一定不足。文章提出一种适用于热轧带钢表面缺陷检测的优化YOLOv5算法,该算法通过IOUK-means++算法调整Anchor聚类锚框设定,并增加Dynamic Head目标检测... 单阶段目标检测网络YOLOv5在处理热轧带钢表面缺陷的特征提取与感受特征融合时存在一定不足。文章提出一种适用于热轧带钢表面缺陷检测的优化YOLOv5算法,该算法通过IOUK-means++算法调整Anchor聚类锚框设定,并增加Dynamic Head目标检测头,引入通道注意力机制(C3_CA),同时结合Hard Swish激活函数与WIoU_Loss边界框回归函数,有效提高热轧带钢表面缺陷检测的综合精度。由NEU-DET数据集测试结果表明,相较于单阶段YOLOv5算法融合结果,优化后的YOLOv5网络模型的均值平均精度(mAP)可提高至75.7%,且网络约束率可有效提升6.1%。上述优化YOLOv5算法对热轧带钢表面缺陷位置勘定、分类指向与影响评估具有有益参考,同时也为金属表面的高精度筛检提供重要支持。 展开更多
关键词 热轧带钢表面缺陷 YOLOv5 IOU-K-means++ Dynamic Head 注意力机制
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改进YOLO v5n的作业人员着装规范性检测方法
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作者 程文冬 刘超 +2 位作者 权程 叶旺盛 王洋 《西安工业大学学报》 CAS 2024年第5期647-655,共9页
为了解决当前作业人员着装规范性(DSOP)检测存在小目标识别率低、环境鲁棒性差等问题。针对DSOP检测中小目标、多重叠、背景复杂等特点,提出基于改进YOLO v5n的算法来实现DSOP检测,首先以E-YOLO架构优化设计提升特征提取和融合效能;其次... 为了解决当前作业人员着装规范性(DSOP)检测存在小目标识别率低、环境鲁棒性差等问题。针对DSOP检测中小目标、多重叠、背景复杂等特点,提出基于改进YOLO v5n的算法来实现DSOP检测,首先以E-YOLO架构优化设计提升特征提取和融合效能;其次以Dynamic Head提升多尺度、多视角下DSOP检测精度;最后以OTA和Soft-NMS算法来改善目标堆叠及背景构图复杂的不利影响。实验结果表明:相较YOLO v5n算法,参数量和浮点运算量分别下降31%和16%,精度值提升了0.2%,召回率值提升了1.7%,mAP@0.5:0.95值提升5.9%。可以为各类复杂场景的着装规范性检测提供可行的技术参考。 展开更多
关键词 DSOP检测 YOLO v5n效能提升 Dynamic Head OTA Soft-NMS
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Long non-coding RNA H19 regulates neurogenesis of induced neural stem cells in a mouse model of closed head injury 被引量:3
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作者 Mou Gao Qin Dong +4 位作者 Zhijun Yang Dan Zou Yajuan Han Zhanfeng Chen Ruxiang Xu 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第4期872-880,共9页
Stem cell-based therapies have been proposed as a potential treatment for neural regeneration following closed head injury.We previously reported that induced neural stem cells exert beneficial effects on neural regen... Stem cell-based therapies have been proposed as a potential treatment for neural regeneration following closed head injury.We previously reported that induced neural stem cells exert beneficial effects on neural regeneration via cell replacement.However,the neural regeneration efficiency of induced neural stem cells remains limited.In this study,we explored differentially expressed genes and long non-coding RNAs to clarify the mechanism underlying the neurogenesis of induced neural stem cells.We found that H19 was the most downregulated neurogenesis-associated lnc RNA in induced neural stem cells compared with induced pluripotent stem cells.Additionally,we demonstrated that H19 levels in induced neural stem cells were markedly lower than those in induced pluripotent stem cells and were substantially higher than those in induced neural stem cell-derived neurons.We predicted the target genes of H19 and discovered that H19 directly interacts with mi R-325-3p,which directly interacts with Ctbp2 in induced pluripotent stem cells and induced neural stem cells.Silencing H19 or Ctbp2 impaired induced neural stem cell proliferation,and mi R-325-3p suppression restored the effect of H19 inhibition but not the effect of Ctbp2 inhibition.Furthermore,H19 silencing substantially promoted the neural differentiation of induced neural stem cells and did not induce apoptosis of induced neural stem cells.Notably,silencing H19 in induced neural stem cell grafts markedly accelerated the neurological recovery of closed head injury mice.Our results reveal that H19 regulates the neurogenesis of induced neural stem cells.H19 inhibition may promote the neural differentiation of induced neural stem cells,which is closely associated with neurological recovery following closed head injury. 展开更多
关键词 closed head injury Ctbp2 induced neural stem cell lncRNA H19 miR-325-3p NEUROGENESIS
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Artificial intelligence-driven radiomics study in cancer:the role of feature engineering and modeling 被引量:1
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作者 Yuan-Peng Zhang Xin-Yun Zhang +11 位作者 Yu-Ting Cheng Bing Li Xin-Zhi Teng Jiang Zhang Saikit Lam Ta Zhou Zong-Rui Ma Jia-Bao Sheng Victor CWTam Shara WYLee Hong Ge Jing Cai 《Military Medical Research》 SCIE CAS CSCD 2024年第1期115-147,共33页
Modern medicine is reliant on various medical imaging technologies for non-invasively observing patients’anatomy.However,the interpretation of medical images can be highly subjective and dependent on the expertise of... Modern medicine is reliant on various medical imaging technologies for non-invasively observing patients’anatomy.However,the interpretation of medical images can be highly subjective and dependent on the expertise of clinicians.Moreover,some potentially useful quantitative information in medical images,especially that which is not visible to the naked eye,is often ignored during clinical practice.In contrast,radiomics performs high-throughput feature extraction from medical images,which enables quantitative analysis of medical images and prediction of various clinical endpoints.Studies have reported that radiomics exhibits promising performance in diagnosis and predicting treatment responses and prognosis,demonstrating its potential to be a non-invasive auxiliary tool for personalized medicine.However,radiomics remains in a developmental phase as numerous technical challenges have yet to be solved,especially in feature engineering and statistical modeling.In this review,we introduce the current utility of radiomics by summarizing research on its application in the diagnosis,prognosis,and prediction of treatment responses in patients with cancer.We focus on machine learning approaches,for feature extraction and selection during feature engineering and for imbalanced datasets and multi-modality fusion during statistical modeling.Furthermore,we introduce the stability,reproducibility,and interpretability of features,and the generalizability and interpretability of models.Finally,we offer possible solutions to current challenges in radiomics research. 展开更多
关键词 Artificial intelligence Radiomics Feature extraction Feature selection Modeling INTERPRETABILITY Multimodalities Head and neck cancer
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Regulation of 2-acetyl-1-pyrroline and grain quality in early-season indica fragrant rice by nitrogen and silicon fertilization under different plantation methods 被引量:1
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作者 Yongjian Chen Lan Dai +7 位作者 Siren Cheng Yong Ren Huizi Deng Xinyi Wang Yuzhan Li Xiangru Tang Zaiman Wang Zhaowen Mo 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第2期511-535,共25页
Fragrant rice has a high market value,and it is a popular rice type among consumers owing to its pleasant flavor.Plantation methods,nitrogen(N)fertilizers,and silicon(Si)fertilizers can affect the grain yield and frag... Fragrant rice has a high market value,and it is a popular rice type among consumers owing to its pleasant flavor.Plantation methods,nitrogen(N)fertilizers,and silicon(Si)fertilizers can affect the grain yield and fragrance of fragrant rice.However,the core commercial rice production attributes,namely the head rice yield(HRY)and 2-acetyl-1-pyrroline(2-AP)content of fragrant rice,under various nitrogen and silicon(N-Si)fertilization levels and different plantation methods remain unknown.The field experiment in this study was performed in the early seasons of 2018 and 2019 with two popular indica fragrant rice cultivars(Yuxiangyouzhan and Xiangyaxiangzhan).They were grown under six N-Si fertilization treatments(combinations of two levels of Si fertilizer,0 kg Si ha^(−1)(Si0)and 150 kg Si ha^(−1)(Si1),and three levels of N fertilizer,0 kg N ha^(−1)(N0),150 kg N ha^(−1)(N1),and 220 kg N ha^(−1)(N2))and three plantation methods(artificial transplanting(AT),mechanical transplanting(MT),and mechanical direct-seeding(MD)).The results showed that the N-Si fertilization treatments and all the plantation methods significantly affected the HRY and 2-AP content and related parameters of the two different fragrant rice cultivars.Compared with the Si0N0 treatment,the N-Si fertilization treatments resulted in higher HRY and 2-AP contents.The rates of brown rice,milled rice,head rice,and chalky rice of the fragrant rice also improved with the N-Si fertilization treatments.The N-Si fertilization treatments increased the activities of N metabolism enzymes and the accumulation of N and Si in various parts of the fragrant rice,and affected their antioxidant response parameters.The key parameters for the HRY and 2-AP content were assessed by redundancy analysis.Furthermore,the structural equation model revealed that the Si and N accumulation levels indirectly affected the HRY by affecting the N metabolism enzyme activity,N use efficiency,and grain quality of fragrant rice.Moreover,high N and Si accumulation directly promoted the 2-AP content or affected the antioxidant response parameters and indirectly regulated 2-AP synthesis.The interactions of the MT method with the N-Si fertilization treatments varied in the fragrant rice cultivars in terms of the HRY and 2-AP content,whereas the MD method was beneficial to the 2-AP content in both fragrant rice cultivars under the N-Si fertilization treatments. 展开更多
关键词 fragrant rice 2-AP content head rice yield mechanical planting NITROGEN silicon
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Laryngopharyngeal reflux disease:Updated examination of mechanisms,pathophysiology,treatment,and association with gastroesophageal reflux disease 被引量:1
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作者 Na Cui Ting Dai +5 位作者 Yang Liu Ya-Yu Wang Jia-Yu Lin Qing-Fan Zheng Dong-Dong Zhu Xue-Wei Zhu 《World Journal of Gastroenterology》 SCIE CAS 2024年第16期2209-2219,共11页
Laryngopharyngeal reflux disease(LPRD)is an inflammatory condition in the laryngopharynx and upper aerodigestive tract mucosa caused by reflux of stomach contents beyond the esophagus.LPRD commonly presents with sympt... Laryngopharyngeal reflux disease(LPRD)is an inflammatory condition in the laryngopharynx and upper aerodigestive tract mucosa caused by reflux of stomach contents beyond the esophagus.LPRD commonly presents with symptoms such as hoarseness,cough,sore throat,a feeling of throat obstruction,excessive throat mucus.This complex condition is thought to involve both reflux and reflex mechanisms,but a clear understanding of its molecular mechanisms is still lacking.Currently,there is no standardized diagnosis or treatment protocol.Therapeutic strategies for LPRD mainly include lifestyle modifications,proton pump inhibitors and endoscopic surgery.This paper seeks to provide a comprehensive overview of the existing literature regarding the mechanisms,pathophysiology and treatment of LPRD.We also provide an in-depth exploration of the association between LPRD and gastroesophageal reflux disease. 展开更多
关键词 Laryngopharyngeal reflux Gastroesophageal reflux Head neck surgery LARYNGITIS OTOLARYNGOLOGY
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UAV-assisted data collection for wireless sensor networks with dynamic working modes 被引量:1
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作者 Jie Chen Jianhua Tang 《Digital Communications and Networks》 SCIE CSCD 2024年第3期805-812,共8页
Wireless Sensor Network(WSN)is a cornerstone of Internet of Things(IoT)and has rich application scenarios.In this work,we consider a heterogeneous WSN whose sensor nodes have a diversity in their Residual Energy(RE).I... Wireless Sensor Network(WSN)is a cornerstone of Internet of Things(IoT)and has rich application scenarios.In this work,we consider a heterogeneous WSN whose sensor nodes have a diversity in their Residual Energy(RE).In this work,to protect the sensor nodes with low RE,we investigate dynamic working modes for sensor nodes which are determined by their RE and an introduced energy threshold.Besides,we employ an Unmanned Aerial Vehicle(UAV)to collect the stored data from the heterogeneous WSN.We aim to jointly optimize the cluster head selection,energy threshold and sensor nodes’working mode to minimize the weighted sum of energy con-sumption from the WSN and UAV,subject to the data collection rate constraint.To this end,we propose an efficient search method to search for an optimal energy threshold,and develop a penalty-based successive convex approximation algorithm to select the cluster heads.Then we present a low-complexity iterative approach to solve the joint optimization problem and discuss the implementation procedure.Numerical results justify that our proposed approach is able to reduce the energy consumption of the sensor nodes with low RE significantly and also saves energy for the whole WSN. 展开更多
关键词 Unmanned aerial vehicle Wireless sensor networks Cluster heads Dynamic working modes
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融合MacBERT和Talking⁃Heads Attention实体关系联合抽取模型
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作者 王春亮 姚洁仪 李昭 《现代电子技术》 北大核心 2024年第5期127-131,共5页
针对现有的医学文本关系抽取任务模型在训练过程中存在语义理解能力不足,可能导致关系抽取的效果不尽人意的问题,文中提出一种融合MacBERT和Talking⁃Heads Attention的实体关系联合抽取模型。该模型首先利用MacBERT语言模型来获取动态... 针对现有的医学文本关系抽取任务模型在训练过程中存在语义理解能力不足,可能导致关系抽取的效果不尽人意的问题,文中提出一种融合MacBERT和Talking⁃Heads Attention的实体关系联合抽取模型。该模型首先利用MacBERT语言模型来获取动态字向量表达,MacBERT作为改进的BERT模型,能够减少预训练和微调阶段之间的差异,从而提高模型的泛化能力;然后,将这些动态字向量表达输入到双向门控循环单元(BiGRU)中,以便提取文本的上下文特征。BiGRU是一种改进的循环神经网络(RNN),具有更好的长期依赖捕获能力。在获取文本上下文特征之后,使用Talking⁃Heads Attention来获取全局特征。Talking⁃Heads Attention是一种自注意力机制,可以捕获文本中不同位置之间的关系,从而提高关系抽取的准确性。实验结果表明,与实体关系联合抽取模型GRTE相比,该模型F1值提升1%,precision值提升0.4%,recall值提升1.5%。 展开更多
关键词 MacBERT BiGRU 关系抽取 医学文本 Talking⁃Heads Attention 深度学习 全局特征 神经网络
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Shock index and its variants as predictors of mortality in severe traumatic brain injury 被引量:2
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作者 Randhall B Carteri Mateus Padilha +2 位作者 Silvaine Sasso de Quadros Eder Kroeff Cardoso Mateus Grellert 《World Journal of Critical Care Medicine》 2024年第1期40-48,共9页
BACKGROUND The increase in severe traumatic brain injury(sTBI)incidence is a worldwide phenomenon,resulting in a heavy disease burden in the public health systems,specifically in emerging countries.The shock index(SI)... BACKGROUND The increase in severe traumatic brain injury(sTBI)incidence is a worldwide phenomenon,resulting in a heavy disease burden in the public health systems,specifically in emerging countries.The shock index(SI)is a physiological parameter that indicates cardiovascular status and has been used as a tool to assess the presence and severity of shock,which is increased in sTBI.Considering the high mortality of sTBI,scrutinizing the predictive potential of SI and its variants is vital.AIM To describe the predictive potential of SI and its variants in sTBI.METHODS This study included 71 patients(61 men and 10 women)divided into two groups:Survival(S;n=49)and Non-survival(NS;n=22).The responses of blood pressure and heart rate(HR)were collected at admission and 48 h after admission.The SI,reverse SI(rSI),rSI multiplied by the Glasgow Coma Score(rSIG),and Age multiplied SI(AgeSI)were calculated.Group comparisons included Shapiro-Wilk tests,and independent samples t-tests.For predictive analysis,logistic regression,receiver operator curves(ROC)curves,and area under the curve(AUC)measurements were performed.RESULTS No significant differences between groups were identified for SI,rSI,or rSIG.The AgeSI was significantly higher in NS patients at 48 h following admission(S:26.32±14.2,and NS:37.27±17.8;P=0.016).Both the logistic regression and the AUC following ROC curve analysis showed that only AgeSI at 48 h was capable of predicting sTBI outcomes.CONCLUSION Although an altered balance between HR and blood pressure can provide insights into the adequacy of oxygen delivery to tissues and the overall cardiac function,only the AgeSI was a viable outcome-predictive tool in sTBI,warranting future research in different cohorts. 展开更多
关键词 Head trauma Critical patient Neuro-cardio axis Predictive tool Clinical practice
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Tilapia Head Glycolipid Alleviates Indomethacin-Induced Gastric Ulcer via Regulating Oxidative Stress and Inflammation Through COX/PGE2 Signaling Pathway in Adult Rats
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作者 WANG Bohui WU Haixing +6 位作者 SHAO Mingyang JIANG Mengqi SU Ruiheng GAO Xia XIA Guanghua SHI Haohao SHEN Xuanri 《Journal of Ocean University of China》 SCIE CAS CSCD 2024年第3期743-754,共12页
The aim of this experiment was to investigate the ameliorative effect and molecular mechanism of tilapia head glycolipid(TH-GL)on indomethacin(IDM)-induced gastric ulcer in male Sprague Dawley(SD)rats.The gastric ulce... The aim of this experiment was to investigate the ameliorative effect and molecular mechanism of tilapia head glycolipid(TH-GL)on indomethacin(IDM)-induced gastric ulcer in male Sprague Dawley(SD)rats.The gastric ulcer model was established by oral administration of 30mgkg^(-1) IDM after 7 days of TH-GL or omeprazole(OME)administration in rats.Then the macroscopic gastric injury symptoms,gastric mucosa protective factor cyclooxygenase 1(COX-1),cyclooxygenase 2(COX-2),prostaglandin E_(2)(PGE_(2)),the levels of oxidative stress,and inflammatory cytokine expression levels in the rats were analyzed.The experimental results showed that multiple ulcers appeared on the gastric surface of the rats in the model group.Compared to the model group,TH-GL significantly alleviated gastric ulcers and reduced the gastric damage index in rats.In addition,TH-GL significantly promoted the expression of constitutive enzyme COX-1 while inhibited the expression of inducible enzyme COX-2,and make PGE2 maintain at normal levels.TH-GL also inhibited oxidative stress and inflammatory responses,increased superoxide dismutase(SOD)activity and glutathione(GSH)content,decreased the level of malondialdehyde(MDA)and the content of pro-inflammatory factor.In conclusion,these results suggested that TH-GL could maintain the expression levels of COX-1 and PGE2 while inhibit the expression of COX-2 in the gastric of rat and then prevent IDM-induced gastric ulcer,which may be related to the regulation of oxidative stress and inflammatory response.Therefore,TH-GL might be a new option for the prevention of gastric diseases induced by IDM. 展开更多
关键词 tilapia head glycolipid indomethacin gastric ulcer oxidative stress INFLAMMATION
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