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Analyzing Cross-domain Transportation Big Data of New York City with Semi-supervised and Active Learning 被引量:4
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作者 Huiyu Sun Suzanne McIntosh 《Computers, Materials & Continua》 SCIE EI 2018年第10期1-9,共9页
The majority of big data analytics applied to transportation datasets suffer from being too domain-specific,that is,they draw conclusions for a dataset based on analytics on the same dataset.This makes models trained ... The majority of big data analytics applied to transportation datasets suffer from being too domain-specific,that is,they draw conclusions for a dataset based on analytics on the same dataset.This makes models trained from one domain(e.g.taxi data)applies badly to a different domain(e.g.Uber data).To achieve accurate analyses on a new domain,substantial amounts of data must be available,which limits practical applications.To remedy this,we propose to use semi-supervised and active learning of big data to accomplish the domain adaptation task:Selectively choosing a small amount of datapoints from a new domain while achieving comparable performances to using all the datapoints.We choose the New York City(NYC)transportation data of taxi and Uber as our dataset,simulating different domains with 90%as the source data domain for training and the remaining 10%as the target data domain for evaluation.We propose semi-supervised and active learning strategies and apply it to the source domain for selecting datapoints.Experimental results show that our adaptation achieves a comparable performance of using all datapoints while using only a fraction of them,substantially reducing the amount of data required.Our approach has two major advantages:It can make accurate analytics and predictions when big datasets are not available,and even if big datasets are available,our approach chooses the most informative datapoints out of the dataset,making the process much more efficient without having to process huge amounts of data. 展开更多
关键词 Big data taxi and uber domain adaptation active learning semi-supervised learning
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Prevalence and factors associated with irritable bowel syndrome among university students in Lebanon:Findings from a cross-sectional study 被引量:3
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作者 Christy Costanian Hala Tamim Shafika Assaad 《World Journal of Gastroenterology》 SCIE CAS 2015年第12期3628-3635,共8页
AIM: To describe the bowel habits and the prevalence of irritable bowel syndrome(IBS) and to investigate the influence of health behavior and social factors on IBS prevalence in university students. METHODS: This cros... AIM: To describe the bowel habits and the prevalence of irritable bowel syndrome(IBS) and to investigate the influence of health behavior and social factors on IBS prevalence in university students. METHODS: This cross-sectional study was conducted at five major universities in Greater Beirut and its suburbs, between February and June 2014. Using a convenience sample, a total of 813 students aged 18 years old and above participated in this study. Participants were asked to complete a comprehensive anonymous questionnaire which detailed characteristics on socio-demographic, health-related, and lifestyle factors, as well as IBS. The ROME Ⅲ criteria were used as a tool to ascertain IBS. A χ2 test was used to determine differences between categorical variables; stepwise logistic regression was used to measure the association between IBS and its risk factors.RESULTS: An overall prevalence of IBS of 20% was recorded among university students. The bivariate analysis showed that females were significantly more likely to report having IBS than males(29.1% vs 18.2%, P < 0.01). Those living at the school dormitory or in a private residence(39.5%) were more likely to have IBS than those living with their families(16.3%)(P < 0.01). The multivariate analysis showed that those who had a relatively high family income level(US$ > 2000) were almost 6 times more likely to report havingIBS than their counterparts.CONCLUSION: This is the first study to describe the nature of IBS among young adults in Lebanon. The prevalence of IBS among university students in our sample was higher than that reported in the West. 展开更多
关键词 IRRITABLE BOWEL syndrome Lebanon Social FACTORS Pr
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Asthma Hospital Admissions and Ambient Air Pollutant Concentrations in New York City
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作者 Carlos E. Restrepo Jeffrey S. Simonoff +1 位作者 George D. Thurston Rae Zimmerman 《Journal of Environmental Protection》 2012年第9期1102-1116,共15页
Air pollution is considered a risk factor for asthma. In this paper, we analyze the association between daily hospital admissions for asthma and ambient air pollution concentrations in four New York City counties. Neg... Air pollution is considered a risk factor for asthma. In this paper, we analyze the association between daily hospital admissions for asthma and ambient air pollution concentrations in four New York City counties. Negative binomial regression is used to model the association between daily asthma hospital admissions and ambient air pollution concentrations. Potential confounding factors such as heat index, day of week, holidays, yearly population changes, and seasonal and long-term trends are controlled for in the models. Nitrogen dioxide (NO2), sulfur dioxide (SO2) and carbon monoxide (CO) show the most consistent statistically significant associations with daily hospitalizations for asthma during the entire period (1996-2000). The associations are stronger for children (0 - 17 years) than for adults (18 - 64 years). Relative risks (RR) for the inter-quartile range (IQR) of same day 24-hour average pollutant concentration and asthma hospitalizations for children for the four county hospitalization totals were: NO2 (IQR = 0.011 ppm, RR = 1.017, 95% CI = 1.001, 1.034), SO2 (IQR = 0.008 ppm, RR = 1.023, 95% CI = 1.004, 1.042), CO (IQR = 0.232 ppm, RR = 1.014, 95% CI = 1.003, 1.025). In the case of ozone (O3) and particulate matter (PM2.5) statistically significant associations were found for daily one-hour maxima values and children’s asthma hospitalization in models that used lagged values for air pollution concentrations. Five-day weighted average lag models resulted in these estimates: O3 (one-hour maxima) (IQR = 0.025 ppm, RR = 1.049, 95% CI = 1.002, 1.098), PM2.5 (one-hour maxima) (IQR = 16.679 μg/m3, RR = 1.055, 95% CI = 1.008, 1.103). In addition, seasonal variations were also explored for PM2.5 and statistically significant associations with daily hospital admissions for asthma were found during the colder months (November-March) of the year. Important differences in pollution effects were found across pollutants, counties, and age groups. The results for PM2.5 suggest that the composition of PM is important to this health outcome, since the major sources of NYC PM differ between winter and summer months. 展开更多
关键词 ASTHMA Air Pollution Epidemiology New YORK CITY Nitrogen Dioxide Sulfur Dioxide Carbon MONOXIDE PARTICULATE Matter Ozone
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Development and characterization of a regional lunar soil simulant for emirates lunar missions 被引量:1
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作者 Bo Peng Prabu Thannasi +2 位作者 Waleed El-Sekelly Tarek Abdoun Kemal Celik 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第9期1305-1315,共11页
Lunar soil simulants(LSS)have been pivotal in the success of past and current lunar missions.They have enhanced the design of lander and rover wheels through interaction studies on the lunar testbed under simulated en... Lunar soil simulants(LSS)have been pivotal in the success of past and current lunar missions.They have enhanced the design of lander and rover wheels through interaction studies on the lunar testbed under simulated environmental conditions.They have also been used to evaluate the geotechnical,geomechanical,and dynamic characteristics of the lunar soil(LS),which is vital for future lunar outposts.While most simulants have focused on either the chemical and mineralogical or geotechnical properties,developing a comprehensive LSS that mimics the lunar soil is of paramount importance for lander and rover soft-landing and future lunar habitation.This article presents the significant development and characterization of the new LSS NYUAD-1,the first regional soil simulant tailored for the planned Emirates lunar missions.The material and geotechnical properties of NYUAD-1,including chemical composition,mineralogy,particle size,morphology,specific gravity,density,shear strength,and compressibility behaviors,were assessed through laboratory tests conducted per ASTM standards.Comparative analysis with authentic lunar regolith and various regolith simulants confirms the significance and applicability of NYUAD-1 for lunar-based research,offering a promising step toward future lunar habitation. 展开更多
关键词 LSS Chemical composition MINERALOGY Density Shear strength COMPRESSIBILITY
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Smart prediction of liquefaction-induced lateral spreading 被引量:1
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作者 Muhammad Nouman Amjad Raja Tarek Abdoun Waleed El-Sekelly 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期2310-2325,共16页
The prediction of liquefaction-induced lateral spreading/displacement(Dh)is a challenging task for civil/geotechnical engineers.In this study,a new approach is proposed to predict Dh using gene expression programming(... The prediction of liquefaction-induced lateral spreading/displacement(Dh)is a challenging task for civil/geotechnical engineers.In this study,a new approach is proposed to predict Dh using gene expression programming(GEP).Based on statistical reasoning,individual models were developed for two topographies:free-face and gently sloping ground.Along with a comparison with conventional approaches for predicting the Dh,four additional regression-based soft computing models,i.e.Gaussian process regression(GPR),relevance vector machine(RVM),sequential minimal optimization regression(SMOR),and M5-tree,were developed and compared with the GEP model.The results indicate that the GEP models predict Dh with less bias,as evidenced by the root mean square error(RMSE)and mean absolute error(MAE)for training(i.e.1.092 and 0.815;and 0.643 and 0.526)and for testing(i.e.0.89 and 0.705;and 0.773 and 0.573)in free-face and gently sloping ground topographies,respectively.The overall performance for the free-face topology was ranked as follows:GEP>RVM>M5-tree>GPR>SMOR,with a total score of 40,32,24,15,and 10,respectively.For the gently sloping condition,the performance was ranked as follows:GEP>RVM>GPR>M5-tree>SMOR with a total score of 40,32,21,19,and 8,respectively.Finally,the results of the sensitivity analysis showed that for both free-face and gently sloping ground,the liquefiable layer thickness(T_(15))was the major parameter with percentage deterioration(%D)value of 99.15 and 90.72,respectively. 展开更多
关键词 Lateral spreading Intelligent modeling Gene expression programming(GEP) Closed-form solution Feature importance
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Role of buccal mucosa graft ureteroplasty in the surgical management of pyeloplasty failure
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作者 Matthew Lee Elizabeth Nagoda +3 位作者 David Strauss Matthew Loecher Michael Stifelman Lee Zhao 《Asian Journal of Urology》 CSCD 2024年第3期373-376,共4页
Objective:Secondary pyeloplasty for recurrent ureteropelvic junction obstructions may be a safe and feasible surgical option for patients.This study aimed to demonstrate outcomes of utilizing a non-transecting buccal ... Objective:Secondary pyeloplasty for recurrent ureteropelvic junction obstructions may be a safe and feasible surgical option for patients.This study aimed to demonstrate outcomes of utilizing a non-transecting buccal mucosa graft ureteroplasty for management of recurrent ureteropelvic junction obstruction after prior failed pyeloplasty.Methods:We performed a retrospective review of our Collaborative of Reconstructive Robotic Ureteral Surgery database for all consecutive patients who underwent buccal mucosa graft ureteroplasty between April 2012 and June 2022 for management of recurrent ureteropelvic junction obstructions after prior failed pyeloplasty.The primary outcome included surgical success which was defined as the absence of flank pain and no obstruction on imaging.Results:Overall,ten patients were included in our analysis.The median stricture length was 2.5(interquartile range[IQR]1.8-4.0)cm.The median operative time was 230.5(IQR 199.5-287.0)min and median estimated blood loss was 50.0(IQR 28.8-102.5)mL.At a median follow-up of 10.3(IQR 6.2-14.8)months,80%of patients were surgically successful and there were no major(ClavieneDindo Grade>2)complications.Conclusion:Buccal mucosa graft ureteroplasty is a valuable non-transecting surgical option for patients with recurrent ureteropelvic junction obstructions who failed prior pyeloplasty and has comparable outcomes to the literature regarding standard transecting techniques. 展开更多
关键词 Ureteral obstruction Buccal mucosa graft PYELOPLASTY ROBOTIC STRICTURE
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Planetary health risks in urban agriculture
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作者 Nilanjana Ganguli Anna Maria Subic +1 位作者 Janani Maheswaran Byomkesh Talukder 《Global Health Journal》 2024年第1期4-10,共7页
Urban agriculture is gaining recognition for its potential contributions to environmental resilience and climate change adaptation,providing advantages such as urban greening,reduced heat island effects,and decreased ... Urban agriculture is gaining recognition for its potential contributions to environmental resilience and climate change adaptation,providing advantages such as urban greening,reduced heat island effects,and decreased air pollution.Moreover,it indirectly supports communities during weather events and natural disasters,ensuring food security and fostering community cohesion.However,concerns about planetary health risks persist in highly urbanized and climate-affected areas.Employing electronic databases such as Web of Science and PubMed and adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines,we identified 55 relevant papers to comprehend the planetary health risks associated with urban agriculture,The literature review identified five distinct health risks related to urban agriculture:(1)trace metal risks in urban farms;(2)health risks associated with wastewater irrigation;(3)zoonotic risks;(4)other health risks;and(5)social and economic risks.The study highlights that urban agriculture,while emphasizing environmental benefits,particularly raises concerns about trace metal bioaccumulation in soil and vegetables,posing health risks for populations.Other well studied risks included wastewater irrigation and backyard livestock farming.The main limitations in the available literature were in studying infectious diseases and antibiotic resistance associated with urban agriculture. 展开更多
关键词 Urban agriculture URBANIZATION Systems-thinking Planetary health impacts Comprehensive risk analysis Planetary Health Risks Analysis of Urban Agriculture Framework(PHRAUAF) HEURISTIC
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RoBGP:A Chinese Nested Biomedical Named Entity Recognition Model Based on RoBERTa and Global Pointer
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作者 Xiaohui Cui Chao Song +4 位作者 Dongmei Li Xiaolong Qu Jiao Long Yu Yang Hanchao Zhang 《Computers, Materials & Continua》 SCIE EI 2024年第3期3603-3618,共16页
Named Entity Recognition(NER)stands as a fundamental task within the field of biomedical text mining,aiming to extract specific types of entities such as genes,proteins,and diseases from complex biomedical texts and c... Named Entity Recognition(NER)stands as a fundamental task within the field of biomedical text mining,aiming to extract specific types of entities such as genes,proteins,and diseases from complex biomedical texts and categorize them into predefined entity types.This process can provide basic support for the automatic construction of knowledge bases.In contrast to general texts,biomedical texts frequently contain numerous nested entities and local dependencies among these entities,presenting significant challenges to prevailing NER models.To address these issues,we propose a novel Chinese nested biomedical NER model based on RoBERTa and Global Pointer(RoBGP).Our model initially utilizes the RoBERTa-wwm-ext-large pretrained language model to dynamically generate word-level initial vectors.It then incorporates a Bidirectional Long Short-Term Memory network for capturing bidirectional semantic information,effectively addressing the issue of long-distance dependencies.Furthermore,the Global Pointer model is employed to comprehensively recognize all nested entities in the text.We conduct extensive experiments on the Chinese medical dataset CMeEE and the results demonstrate the superior performance of RoBGP over several baseline models.This research confirms the effectiveness of RoBGP in Chinese biomedical NER,providing reliable technical support for biomedical information extraction and knowledge base construction. 展开更多
关键词 BIOMEDICINE knowledge base named entity recognition pretrained language model global pointer
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What Are the Current and Developing Treatments for Cotard’s Syndrome, Alice in Wonderland Syndrome, and Catatonic Schizophrenia?
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作者 Anuva Ghosh 《Open Journal of Psychiatry》 2024年第3期179-205,共27页
Purpose: Cotard’s syndrome, Alice in Wonderland Syndrome, and Catatonia are all rare psychiatric disorders that have relatively little research regarding their treatments. The aim of this article is to highlight any ... Purpose: Cotard’s syndrome, Alice in Wonderland Syndrome, and Catatonia are all rare psychiatric disorders that have relatively little research regarding their treatments. The aim of this article is to highlight any gaps in knowledge regarding represented demographics in these treatment studies, and to discuss the current and upcoming treatment options. Background: This literature review explores under-researched psychiatric conditions: Cotard’s syndrome, Alice in Wonderland syndrome, and Catatonic Schizophrenia. Understanding psychiatric disorders requires basic knowledge of brain anatomy. These conditions are often result of or associated with neurological issues, such as migraines or tumors. The brain has eight lobes, two of four kinds: frontal, parietal, occipital, and temporal lobes, which all govern different functions and abilities. Frontal lobes control judgment, decision-making, personality traits, and fine motor movements. Parietal lobes interpret pain and temperature, occipital lobes handle visual stimuli, and temporal lobes enable hearing. The pre-frontal cortex is associated with high intelligence, psychotic traits, and psychosis. The Broca’s Area in the frontal lobes controls expressive language. These areas and divisions of the brain contribute to the complexity of the psychiatric disorders discussed in this review. Introduction: Cotard’s syndrome is a psychiatric disorder characterized by delusions of being dead or not having certain limbs or organs. It is believed that there is a disconnect between their fusiform face area and the amygdala, causing a lack of familiarity between one’s mind and body. Alice in Wonderland Syndrome (AIWS) is another psychiatric disorder which is characterized by visual hallucinations, such as distorted perceptions of color, size, distance, and speed. The most common symptoms include micropsia and macropsia. Catatonia/Catatonic Schizophrenia is an uncommon type of schizophrenia. This type of schizophrenia is characterized by motor rigidity, verbal rigidity, the flat effect, psychomotor retardation, waxy flexibility, and overall negative symptoms. Thus, these people may come off as emotionally detached, and able to stay frozen in odd positions for periods on end. Treatments and Results: Cotard’s syndrome seemed to be most effectively treated by ECT (electroconvulsive therapy). Alice in Wonderland Syndrome (AIWS) had the highest positive responses to treatment by Valproate (an anti-epileptic drug), as well as intervention to treat the associated neurological conditions they had. Catatonia/Catatonic Schizophrenia seemed to be most effectively treated with a combination of benzodiazepines and ECT. Discussion and Demographics: In all 3 disorders, the Latino and African communities were underrepresented. There also seemed to be an underrepresentation of men in Cotard’s syndrome, and of women in Alice in Wonderland Syndrome. Japan and India seemed to have the highest density of treatment studies in all 3 disorders. 展开更多
关键词 Component Formatting Style Styling Alice in Wonderland Syndrome Cotard’s Syndrome Cotard’s Delusion AIWS CATATONIA Catatonic Schizophrenia SCHIZOPHRENIA Psychiatric medication Rare Disorders PSYCHIATRY
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Understanding the correlation between energy-state mismatching and open-circuit voltage loss in bulk heterojunction solar cells
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作者 Hyun-Seock Yang Danbi Kim +7 位作者 Chang-Mok Oh Vellaiappillai Tamilavan Pesi MHangoma Hojun Yi Bo RLee Insoo Shin In-Wook Hwang Sung Heum Park 《Carbon Energy》 SCIE EI CAS CSCD 2024年第5期164-174,共11页
Photoinduced intermolecular charge transfer(PICT)determines the voltage loss in bulk heterojunction(BHJ)organic photovoltaics(OPVs),and this voltage loss can be minimized by inducing efficient PICT,which requires ener... Photoinduced intermolecular charge transfer(PICT)determines the voltage loss in bulk heterojunction(BHJ)organic photovoltaics(OPVs),and this voltage loss can be minimized by inducing efficient PICT,which requires energy-state matching between the donor and acceptor at the BHJ interfaces.Thus,both geometrically and energetically accessible delocalized state matching at the hot energy level is crucial for achieving efficient PICT.In this study,an effective method for quantifying the hot state matching of OPVs was developed.The degree of energy-state matching between the electron donor and acceptor at BHJ interfaces was quantified using a mismatching factor(MF)calculated from the modified optical density of the BHJ.Furthermore,the correlation between the open-circuit voltage(Voc)of the OPV device and energy-state matching at the BHJ interface was investigated using the calculated MF.The OPVs with small absolute MF values exhibited high Voc values.This result clearly indicates that the energy-state matching between the donor and acceptor is crucial for achieving a high Voc in OPVs.Because the MF indicates the degree of energy-state matching,which is a critical factor for suppressing energy loss,it can be used to estimate the Voc loss in OPVs. 展开更多
关键词 bulk heterojunction open circuit voltage organic photovoltaics photoinduced charge transfer voltage loss
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Smoking cessation prior to elective total joint arthroplasty results in sustained abstinence postoperatively
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作者 Billy Insup Kim Jeffrey O'Donnell +4 位作者 Colleen M Wixted Thorsten Markus Seyler William A Jiranek Michael Paul Bolognesi Sean Patrick Ryan 《World Journal of Orthopedics》 2024年第7期627-634,共8页
BACKGROUND Tobacco use is a well-documented modifiable risk factor for perioperative complications.AIM To determine the tobacco abstinence rates of patients who made cessation efforts prior to a total joint arthroplas... BACKGROUND Tobacco use is a well-documented modifiable risk factor for perioperative complications.AIM To determine the tobacco abstinence rates of patients who made cessation efforts prior to a total joint arthroplasty(TJA)procedure.METHODS A retrospective evaluation was performed on 88 self-reported tobacco users who underwent TJA between 2014-2022 and had tobacco cessation dates within 3 mo of surgery.Eligible patients were contacted via phone survey to understand their tobacco use pattern,and patient reported outcomes.A total of 37 TJA patients participated.RESULTS Our cohort was on average 61-years-old,60%(n=22)women,with an average body mass index of 30 kg/m^(2).The average follow-up time was 2.9±1.9 years.A total of 73.0%(n=27)of patients endorsed complete abstinence from tobacco use prior to surgery.Various cessation methods were used perioperatively including prescription therapy(13.5%),over the counter nicotine replacement(18.9%),cessation programs(5.4%).At final follow up,43.2%(n=16)of prior tobacco smokers reported complete abstinence.Patients who were able to maintain cessation postoperatively had improved Patient-Reported Outcomes Measurement Information System(PROMIS)-10 mental health scores(49 vs 58;P=0.01),and hip dysfunction and osteoarthritis outcome score for joint replacement(HOOS.JR)scores(63 vs 82;P=0.02).No patients in this cohort had a prosthetic joint infection or required revision surgery.CONCLUSION We report a tobacco cessation rate of 43.2%in patients undergoing elective TJA nearly 3 years postoperatively.Patients undergoing TJA who were able to remain abstinent had improved PROMIS-10 mental health scores and HOOS.JR scores.The perioperative period provides clinicians a unique opportunity to assist active tobacco smokers with cessation efforts and improve postoperative outcomes. 展开更多
关键词 Smoking cessation Total joint arthroplasty OUTCOMES Tobacco use Postoperative abstinence
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Screening for metabolic dysfunction-associated fatty liver disease:Time to discard the emperor’s clothes of normal liver enzymes?
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作者 Chen-Xiao Huang Xiao-Dong Zhou +1 位作者 Calvin Q Pan Ming-Hua Zheng 《World Journal of Gastroenterology》 SCIE CAS 2024年第22期2839-2842,共4页
Metabolic dysfunction-associated fatty liver disease(MAFLD)is the most prevalent chronic liver condition worldwide.Current liver enzyme-based screening methods have limitations that may missed diagnoses and treatment ... Metabolic dysfunction-associated fatty liver disease(MAFLD)is the most prevalent chronic liver condition worldwide.Current liver enzyme-based screening methods have limitations that may missed diagnoses and treatment delays.Regarding Chen et al,the risk of developing MAFLD remains elevated even when alanine aminotransferase levels fall within the normal range.Therefore,there is an urgent need for advanced diagnostic techniques and updated algorithms to enhance the accuracy of MAFLD diagnosis and enable early intervention.This paper proposes two potential screening methods for identifying individuals who may be at risk of developing MAFLD:Lowering these thresholds and promoting the use of noninvasive liver fibrosis scores. 展开更多
关键词 Metabolic dysfunction-associated fatty liver disease Non-alcoholic fatty liver disease Alanine aminotransferase Liver enzymes SCREENING Noninvasive liver fibrosis scores
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A Critical Assessment of Professor Todd Ryan’s, “Philo on the ‘Incomprehensible Nature of the Supreme Being’ in Dialogues 2”
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作者 Stanley Tweyman 《Philosophy Study》 2024年第2期91-96,共6页
I begin my comments by acknowledging that Professor Ryan is correct when he states early in his paper that Philo makes common cause with Demea by arguing that philosophical reflection can yield no knowledge of the nat... I begin my comments by acknowledging that Professor Ryan is correct when he states early in his paper that Philo makes common cause with Demea by arguing that philosophical reflection can yield no knowledge of the nature or essence of the divine being. Ryan asserts that Philo’s defense of this claim, as set out in the third and fourth paragraphs in Part 2, has not received the attention it deserves from commentators. This, according to Ryan, is surprising, since, if Philo is successful here, he will have effectively shut down the project of natural theology, before it can even begin. Ryan goes further, citing my work, Scepticism and Belief in Hume’s Dialogues Concerning Natural Religion (The Hague: Martinus Nijhoff, 1986) to say that Philo’s challenge receives no direct answer from Cleanthes. Instead, Cleanthes proceeds directly to formulate his version of the Argument from Design. Ryan concludes his introductory remarks by asserting that, in these two paragraphs, Philo offers not one, but two, distinct arguments for the conclusion that we can achieve no strictly philosophical knowledge of the nature of God. He then proceeds to flesh out these two arguments, and attempts to show that neither of Philo’s objections is ultimately telling against Cleanthes’ experimental natural theology. 展开更多
关键词 STRICTLY CLEAN NEITHER
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A state-of-the-art review on recent advances in the fabrication and characteristics of magnesium-based alloys in biomedical applications
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作者 Fatemeh Zahra Akbarzadeh Masoud Sarraf +4 位作者 Erfan Rezvani Ghomi Vishnu Vijay Kumar Mojtaba Salehi Seeram Ramakrishna Sungchul Bae 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第7期2569-2594,共26页
Magnesium(Mg)and its alloys have recently gained increasing attention in the biomedical field as promising biodegradable materials with harmless degradation products.Magnesium-based alloys have a wide range of biomedi... Magnesium(Mg)and its alloys have recently gained increasing attention in the biomedical field as promising biodegradable materials with harmless degradation products.Magnesium-based alloys have a wide range of biomedical applications because of their outstanding biocompatibility and unique mechanical properties.Widespread use of Mg-based biomedical devices eliminates the need for post-healing biomaterial removal surgery and minimizes the negative consequences of the implantation of permanent biomaterials,including stress shielding and undesired metal ion release in the body.This paper provides a literature review on the properties and manufacturing methods of Mgbased alloys for biomedical applications,including orthopedic implants,cardiovascular applications,surgical wires and staplers,and antitumor activities.Each application of Mg-based biomaterials is investigated from a biological perspective,including matching functional properties,biocompatibility,host tissue responses,and anti-microbial strategies,along with potential additive manufacturing technologies for these applications.Finally,an outlook is presented to provide recommendations for Mg-based biomaterials in the future. 展开更多
关键词 Mg-based alloys BIOCOMPATIBILITY Anti-microbial strategies Additive manufacturing Mg implants
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Impact of phytoconstituents on oral health practices:a post COVID-19 observation
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作者 Harsh Kumar Reena Singh +9 位作者 Daljeet Singh Dhanjal Chirag Chopra Natália Cruz-Martins Gheyath K.Nasrallah Amin F.Majdalawieh Sivakumar Manickam Shahida Anusha Siddiqui Dinesh Kumar Indu Sharma Varun Sharma 《Food Science and Human Wellness》 SCIE CAS CSCD 2024年第5期2386-2400,共15页
Appropriate oral hygiene significantly reduces the possibility of oral infections.However,dental caries and periodontal diseases are major oral health issues causing chronic diseases due to poor oral health.Recently,h... Appropriate oral hygiene significantly reduces the possibility of oral infections.However,dental caries and periodontal diseases are major oral health issues causing chronic diseases due to poor oral health.Recently,herbal compounds have gained interest in maintaining oral health.Extracts of burdock root(Arctium),noni fruit(Morinda citrifolia),and neem leaf(Azadirachta indica)are now used as intracanal medicaments in endodontics and periodontics.Plectranthus amboinicus species and other plants produces essential oil likeβ-caryophyllene,p-cymene,andγ-terpinene can exhibit antibacterial activity;highlighting phytoconstituents plays a vital role in oral health.The COVID-19 pandemic highlighted the importance of hygiene and sanitization,to curb SARS-CoV-2.Oral cavity is among the gateways for virus entry into saliva.Saliva is a potential reservoir of SARS-CoV-2,and there is an increased risk of infection if there is any fissure in the mouth.This enables entry of virus into the vascular system through gingival or periodontal pocket,possibly reaching lung periphery then to lung vessels by interacting with endothelial surface receptors triggering pulmonary vasoconstriction and lung damage due to endothelial dysfunction.This review aims to draw attention to the possible route of SARS-CoV-2 infection via the oral cavity and the importance of oral hygiene against COVID-19. 展开更多
关键词 COVID-19 SARS-CoV-2 ORAL HYGIENE MICROBIOTA PHYTOCHEMICALS
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Global trends in hepatitis C-related hepatocellular carcinoma mortality:A public database analysis(1999-2019)
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作者 Hassam Ali Fnu Vikash +7 位作者 Vishali Moond Fatima Khalid Abdur Rehman Jamil Dushyant Singh Dahiya Amir Humza Sohail Manesh Kumar Gangwani Pratik Patel Sanjaya K Satapathy 《World Journal of Virology》 2024年第1期69-83,共15页
BACKGROUND Hepatitis C is the leading cause of chronic liver disease worldwide and it significantly contributes to the burden of hepatocellular carcinoma(HCC).However,there are marked variations in the incidence and m... BACKGROUND Hepatitis C is the leading cause of chronic liver disease worldwide and it significantly contributes to the burden of hepatocellular carcinoma(HCC).However,there are marked variations in the incidence and mortality rates of HCC across different geographical regions.With the advent of new widely available treatment modalities,such as direct-acting antivirals,it is becoming increasingly imperative to understand the temporal and geographical trends in HCC mortality associated with Hepatitis C.Furthermore,gender disparities in HCC mortality related to Hepatitis C are a crucial,yet underexplored aspect that adds to the disease's global impact.While some studies shed light on gender-specific trends,there is a lack of comprehensive data on global and regional mortality rates,particularly those highlighting gender disparities.This gap in knowledge hinders the development of targeted interventions and resource allocation strategies.DISCUSSION The results of our study show an overall decline in the mortality rates of patients with hepatitis C-related HCC over the last two decades.Notably,females exhibited a remarkable decrease in mortality compared to males.Regionally,East Asia and the Pacific displayed a significant decline in mortality,while Europe and Central Asia witnessed an upward trend.Latin America and the Caribbean also experienced an increase in mortality rates.However,no significant difference was observed in the Middle East and North Africa.North America exhibited a notable upward trend.South Asia and Sub-Saharan Africa significantly declined throughout the study period.This raises the hope of identifying areas for implementing more targeted resources.Despite some progress,multiple challenges remain in meeting the WHO 2030 goal of eliminating viral hepatitis[24]. 展开更多
关键词 CARCINOMA HEPATOCELLULAR Antiviral agents Global Burden of Disease Quality indicators Health care Liver neoplasms Hepatitis C Chronic hepatitis C
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T1骨盆角与退变性脊柱侧凸患者脊柱-骨盆矢状面平衡以及生活质量的相关性分析 被引量:17
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作者 乔军 邱勇 +5 位作者 朱锋 Themistocles Protopsaltis 朱泽章 徐磊磊 刘臻 钱邦平 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2014年第8期686-690,共5页
目的:探讨T1骨盆角(T1 pelvic angle,TPA)能否反映退变性脊柱侧凸(degenerative scoliosis,DS)患者脊柱-骨盆矢状面的整体及局部平衡,及其与DS患者生活质量的关系。方法:回顾性分析2007年2月-2011年12月在我院接受手术治疗的DS患... 目的:探讨T1骨盆角(T1 pelvic angle,TPA)能否反映退变性脊柱侧凸(degenerative scoliosis,DS)患者脊柱-骨盆矢状面的整体及局部平衡,及其与DS患者生活质量的关系。方法:回顾性分析2007年2月-2011年12月在我院接受手术治疗的DS患者资料。纳入标准:(1)随访时间超过2年;(2)有完整临床及影像学资料。排除标准:(1)既往接受过脊柱手术;(2)同时伴有髋、膝关节病变影响正常的站立姿势。共76例DS患者纳入研究,男9例,女67例,年龄45-72岁,平均58.2±6.1岁。Cobb角32°-74°,平均42.6°±6.1°。顶椎位于L2椎体3例,L2/3椎间盘4例,L3椎体26例,L3/4椎间盘23例,L4椎体16例,L4/5椎间盘4例。随访2.1-6.4年,平均3.7年。术前及末次随访时均摄自然站立位全脊柱正、侧位X线片,同时填写ODI、VAS及SRS-22量表。测量胸椎后凸角(thoracic kyphosis,TK)、胸腰段后凸角(thoracolumbar kyphosis,TLK)、腰椎前凸角(lumbar lordosis,LL)、骨盆入射角(pelvic incidence,PI)、骶骨倾斜角(sacral slope,SS)、骨盆倾斜角(pelvic tilt,PT)、矢状面平衡(sagittal vertical axis,SVA)和TPA。采用Spearman检验分别对术前、末次随访时的SVA和TPA与其他术前、末次随访时的脊柱-骨盆参数作相关性分析,同时分析SVA和TPA术前、末次随访时的变化值与其他脊柱-骨盆参数术前、末次随访时的变化值的相关性。分析SVA和TPA术前、末次随访时的变化值与ODI、VAS及SRS-22总分术前、末次随访时的变化值的相关性。结果:术前TPA与术前LL、SS、PT、PI及SVA显著相关(P〈0.05),与术前TK、TLK无相关性(P〉0.05);末次随访时TPA均与末次随访时的LL、SS、PT、PI及SVA显著相关(P〈0.05),与末次随访时TK、TLK无相关性(P〉0.05);TPA术前、末次随访时的变化值与LL、SS、PT、PI及SVA术前、末次随访时的变化值显著相关(P〈0.05),与TK、TLK的变化值无相关性(P〉0.05);TPA术前、末次随访时的变化值与ODI评分、VAS评分术前、末次随访时的变化值正相关(P〈0.05),与SRS-22总分变化值负相关(P〈0.05)。术前SVA与术前LL、TPA显著相关(P〈0.05),与术前TK、TLK、SS、PT、PI无相关性(P〉0.05);末次随访时SVA与末次随访时TPA显著相关(P〈0.05),与末次随访时TK、TLK、SS、PT、PI、LL无相关性(P〉0.05);SVA术前、末次随访时的变化值与LL、TPA术前、末次随访时的变化值显著相关(P〈0.05),与TK、TLK、SS、PT术前、末次随访时的变化值无相关性(P〉0.05);SVA术前、末次随访时的变化值与ODI评分、VAS评分术前、末次随访时的变化值正相关(P〈0.05),与SRS-22总分变化值负相关(P〈0.05)。结论:TPA整合了整体和局部脊柱-骨盆矢状面平衡的信息,能够反映DS患者脊柱-骨盆矢状面的整体及局部平衡,且与DS患者的生活质量密切相关,对于DS重建手术有着重要的指导意义。 展开更多
关键词 退变性脊柱侧凸 脊柱-骨盆矢状面平衡 T1骨盆角 生活质量
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全轻页岩陶粒混凝土的强度影响因素 被引量:20
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作者 杨健辉 陈静 +2 位作者 张鹏 秦本东 薛晓 《河南理工大学学报(自然科学版)》 CAS 北大核心 2014年第5期664-670,共7页
因轻骨料混凝土的强度影响因素较多,且相关规程对配合比设计参数规定的范围又较宽,从而导致配合比设计困难.因此,为了确定最佳配合比设计参数对全轻页岩陶粒混凝土进行了一系列强度因素影响试验.结果表明,页岩陶粒混凝土强度主要取决于... 因轻骨料混凝土的强度影响因素较多,且相关规程对配合比设计参数规定的范围又较宽,从而导致配合比设计困难.因此,为了确定最佳配合比设计参数对全轻页岩陶粒混凝土进行了一系列强度因素影响试验.结果表明,页岩陶粒混凝土强度主要取决于水泥砂浆强度、骨料自身强度和预湿时间.虽然混凝土强度与水胶比成反比,并与砂率的影响规律相同,但都有一个强度上限值;其次,轴心与立方体抗压强度接近,7 d与28 d抗压强度也较接近;第三,其弹性模量较普通混凝土低,而峰值应变与总应变则较普通混凝土大,因此,更适宜于抗震与抗爆炸冲击等结构. 展开更多
关键词 全轻混凝土 页岩陶粒与陶砂 水胶比 砂率 弹性模量
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脑卒中住院患者健康素养与健康行为的相关性研究 被引量:54
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作者 李娟 Bei Wu +3 位作者 刘纪汝 田芳 赵雪姣 周莹 《护理学杂志》 CSCD 北大核心 2019年第11期13-15,共3页
目的探讨脑卒中住院患者健康素养与健康行为的相关性,为患者康复护理干预提供参考。方法便利选取贵阳市4所三级甲等医院卒中单元和康复医学科的康复期脑卒中患者508例,采用慢性病患者健康素养调查量表、健康促进生活方式量表Ⅱ、一般情... 目的探讨脑卒中住院患者健康素养与健康行为的相关性,为患者康复护理干预提供参考。方法便利选取贵阳市4所三级甲等医院卒中单元和康复医学科的康复期脑卒中患者508例,采用慢性病患者健康素养调查量表、健康促进生活方式量表Ⅱ、一般情况调查表进行调查。结果脑卒中患者健康素养总得分为(31.67±8.79)分,健康行为总得分为(127.18±24.19)分。患者健康素养水平与健康行为水平呈正相关(r=0.633,P<0.01)。结论脑卒中患者健康素养与健康行为呈正相关,护理人员应采取措施提高患者健康素养,促使其形成良好的健康行为。 展开更多
关键词 脑卒中 健康素养 健康行为 生活方式 康复干预 运动锻炼 延续护理
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12285例体检者局部脂肪含量与骨密度的相关性研究 被引量:17
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作者 徐君翔 钱志远 +5 位作者 李光飞 张鹏 沈光思 Xi Huang 林华 徐又佳 《中国骨质疏松杂志》 CAS CSCD 北大核心 2014年第8期863-868,共6页
目的了解腰椎周围及髋部周围脂肪比例与骨密度的关系,探讨局部脂肪含量对骨密度检测值的影响。方法收集12285例正常体检人群双能X线骨密度(DEXA)检测的骨密度数据(腰椎和髋部),同时收集每人"骨密度局部模式"所检测的"腰... 目的了解腰椎周围及髋部周围脂肪比例与骨密度的关系,探讨局部脂肪含量对骨密度检测值的影响。方法收集12285例正常体检人群双能X线骨密度(DEXA)检测的骨密度数据(腰椎和髋部),同时收集每人"骨密度局部模式"所检测的"腰椎周围"及"髋部周围"脂肪比例值数据,按照性别、体重指数(BMI)对本组检测人员分组,采用单因素方差分析和多元线性回归统计方法,回顾分析局部脂肪比例与骨密度之间的相关性。结果单因素方差分析:在髋部脂肪比例高的组中,各组骨密度的平均值均较低。男性髋部和腰椎骨密度在腰周脂肪比例高的组别中平均值较高,而女性腰椎骨密度在腰周脂肪比例高的组中平均值较低,髋部的骨密度则没有明显的改变。多元线性回归分析:女性组:骨密度与身高(r=0.276~0.497)和体重(r=0.216~0.526)正相关,与年龄负相关(r=-0.730~-0.454),与髋部周围脂肪比例负相关(r=-0.369~-0.352),与腰椎周围脂肪比例负相关(r=-0.400~-0.245)。在多元回归分析中,控制其他变量后,腰椎骨密度和腰椎周围脂肪比例无统计学上的相关性。腰椎骨密度和髋部周围脂肪比、髋部骨密度和两个部位的脂肪比均呈负相关,并且在BMI高的组中,负相关性较为显著,其中髋部脂肪比和腰椎骨密度负相关性最为显著(r=-0.220~-0.194)。男性组:骨密度与身高(r=0.139~0.388)和体重呈正相关,与年龄相关性差(r=-0.494~0.077),与髋部周围脂肪比例负相关(r=-0.400~-0.216),与腰椎周围脂肪比例负相关(r=-0.329~-0.223)。在多元回归分析中,控制其他变量后,腰椎骨密度和腰椎周围脂肪比例在BMI<20 kg/m2组中呈显著的正相关(r=0.294),在其它组中没有显著的相关性。腰椎骨密度和髋部周围脂肪比、髋部骨密度和两个部位的脂肪比例呈负相关,其中腰椎骨密度和髋部周围脂肪比的负相关性最为显著(r=-0.207~-0.108),并且在BMI低的组中,负相关程度较高。结论脂肪含量对骨密度有显著的影响,局部脂肪比例增加骨密度下降显著(成年女性BMI指数越高相关性越高);脂肪分布对骨密度影响明显,髋部脂肪比(皮下脂肪为主)与腰椎骨密度的负相关性最显著。 展开更多
关键词 骨密度 体质指数 脂肪含量
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