Cellulose tris(4-methylphenylcarbamate), amylosetris(3,5-di-methylphenylcarbamate) and amylose tris (phenylcarbamate) were prepared by the methodreported by Okamoto and were coated onto an aminopropylated mesoporous s...Cellulose tris(4-methylphenylcarbamate), amylosetris(3,5-di-methylphenylcarbamate) and amylose tris (phenylcarbamate) were prepared by the methodreported by Okamoto and were coated onto an aminopropylated mesoporous spherical silica gel. Thesefinal products were used as chiral stationary phases of high performance liquid chromatography forthe eighteen structurally related biphenyl compounds. The resolution was made using normal-phasemethodology with a mobile phase consisting of n-hexane-alcohol (ethanol, 1-propanol, 2-pro-panol or1-butanol). The effects of various aliphatic alcohols in the mobile phase were studied. Thestructural features of the solutes that influence then- k′ were discussed. A dominant effect oftrifluoroacetic acid on chiral separation of acidic solutes was noted.展开更多
文摘Cellulose tris(4-methylphenylcarbamate), amylosetris(3,5-di-methylphenylcarbamate) and amylose tris (phenylcarbamate) were prepared by the methodreported by Okamoto and were coated onto an aminopropylated mesoporous spherical silica gel. Thesefinal products were used as chiral stationary phases of high performance liquid chromatography forthe eighteen structurally related biphenyl compounds. The resolution was made using normal-phasemethodology with a mobile phase consisting of n-hexane-alcohol (ethanol, 1-propanol, 2-pro-panol or1-butanol). The effects of various aliphatic alcohols in the mobile phase were studied. Thestructural features of the solutes that influence then- k′ were discussed. A dominant effect oftrifluoroacetic acid on chiral separation of acidic solutes was noted.
