半数以上早发性卵巢功能不全(Premature ovarian insufficiency, POI)病因尚未明确,其中免疫因素占4%~30%。POI可单独发病,但有时也与自身免疫性疾病并存,如自身免疫性甲状腺疾病(AITD)、原发性慢性肾上腺皮质功能减退症(Addsion病)、...半数以上早发性卵巢功能不全(Premature ovarian insufficiency, POI)病因尚未明确,其中免疫因素占4%~30%。POI可单独发病,但有时也与自身免疫性疾病并存,如自身免疫性甲状腺疾病(AITD)、原发性慢性肾上腺皮质功能减退症(Addsion病)、系统性红斑狼疮等。因免疫系统异常活跃,卵巢常为其相关攻击靶点,自身免疫抗体(抗卵巢抗体、类固醇自身抗体)、免疫细胞、肿瘤坏死因子α、白细胞介素6等与POI的免疫相关发病机制有着密切的联系。The etiology of more than half of premature ovarian insufficiency (POI) has not been clarified, with immunologic factors accounting for 4%~30% of the cases. POI can develop alone, but sometimes coexists with autoimmune diseases, such as autoimmune thyroid disease (AITD), primary chronic adrenocortical hypoplasia (Addsion disease), systemic lupus erythematosus (SLE), and others. Due to the abnormal activity of the immune system, the ovary is often the target of attack, and autoimmune antibodies (anti-ovarian antibodies, steroid autoantibodies), immune cells, tumor necrosis factor-alpha, and interleukin 6 are closely related to the immune-related pathogenesis of POI.展开更多
报道了浙江省的2个浙江分布新记录种,分别是发现于遂昌九龙山的梵净山石斛兰Dendrobium fanjingshanense Z.H.Tsi ex X.H.Jin et Y.W.Zhang和发现于永嘉龙湾潭蚂蝗七Chirita fimbrisepala Hand.-Mazz.。引证标本存于浙江林学院植物标本...报道了浙江省的2个浙江分布新记录种,分别是发现于遂昌九龙山的梵净山石斛兰Dendrobium fanjingshanense Z.H.Tsi ex X.H.Jin et Y.W.Zhang和发现于永嘉龙湾潭蚂蝗七Chirita fimbrisepala Hand.-Mazz.。引证标本存于浙江林学院植物标本馆(ZJFC)。展开更多
文摘半数以上早发性卵巢功能不全(Premature ovarian insufficiency, POI)病因尚未明确,其中免疫因素占4%~30%。POI可单独发病,但有时也与自身免疫性疾病并存,如自身免疫性甲状腺疾病(AITD)、原发性慢性肾上腺皮质功能减退症(Addsion病)、系统性红斑狼疮等。因免疫系统异常活跃,卵巢常为其相关攻击靶点,自身免疫抗体(抗卵巢抗体、类固醇自身抗体)、免疫细胞、肿瘤坏死因子α、白细胞介素6等与POI的免疫相关发病机制有着密切的联系。The etiology of more than half of premature ovarian insufficiency (POI) has not been clarified, with immunologic factors accounting for 4%~30% of the cases. POI can develop alone, but sometimes coexists with autoimmune diseases, such as autoimmune thyroid disease (AITD), primary chronic adrenocortical hypoplasia (Addsion disease), systemic lupus erythematosus (SLE), and others. Due to the abnormal activity of the immune system, the ovary is often the target of attack, and autoimmune antibodies (anti-ovarian antibodies, steroid autoantibodies), immune cells, tumor necrosis factor-alpha, and interleukin 6 are closely related to the immune-related pathogenesis of POI.
文摘报道了浙江省的2个浙江分布新记录种,分别是发现于遂昌九龙山的梵净山石斛兰Dendrobium fanjingshanense Z.H.Tsi ex X.H.Jin et Y.W.Zhang和发现于永嘉龙湾潭蚂蝗七Chirita fimbrisepala Hand.-Mazz.。引证标本存于浙江林学院植物标本馆(ZJFC)。