1文献来源Farooqi AS, Holliday EB, Allen PK et al. Prophylactic cranial irradiation after definitive chemoradiotherapy for limited-stage small cell lung cancer: Do all patients benefit?[J]. Radiother Oncol,2017...1文献来源Farooqi AS, Holliday EB, Allen PK et al. Prophylactic cranial irradiation after definitive chemoradiotherapy for limited-stage small cell lung cancer: Do all patients benefit?[J]. Radiother Oncol,2017,122(2):307-312.2证据水平3b。3背景预防性全脑放疗(prophylactic cranial irradiation,PCI)在根治性放化疗后完全缓解的局限期小细胞肺癌中能够降低脑转移发生率,延长总生存期。近期研究指出对于≥70岁的局限期小细胞肺癌患者,在能耐受毒性的基础上,应考虑根治性放化疗。然而尚缺乏PCI对这一患者亚群生存影响的证据。展开更多
文摘1文献来源Farooqi AS, Holliday EB, Allen PK et al. Prophylactic cranial irradiation after definitive chemoradiotherapy for limited-stage small cell lung cancer: Do all patients benefit?[J]. Radiother Oncol,2017,122(2):307-312.2证据水平3b。3背景预防性全脑放疗(prophylactic cranial irradiation,PCI)在根治性放化疗后完全缓解的局限期小细胞肺癌中能够降低脑转移发生率,延长总生存期。近期研究指出对于≥70岁的局限期小细胞肺癌患者,在能耐受毒性的基础上,应考虑根治性放化疗。然而尚缺乏PCI对这一患者亚群生存影响的证据。