S)-(+)-2-Amino-1-propanol, the key chiral intermediate of levofloxacin, was preparation from L-2-aminopropionic acid by methyl esterification, and then direct reduction by KBH 4 without purification with an overall yi...S)-(+)-2-Amino-1-propanol, the key chiral intermediate of levofloxacin, was preparation from L-2-aminopropionic acid by methyl esterification, and then direct reduction by KBH 4 without purification with an overall yield of 70%.展开更多
文摘S)-(+)-2-Amino-1-propanol, the key chiral intermediate of levofloxacin, was preparation from L-2-aminopropionic acid by methyl esterification, and then direct reduction by KBH 4 without purification with an overall yield of 70%.
