Atherosclerosis (As) is a common disease, also the pathological basis of many cardiovascular diseases and cephalovascular diseases. In Traditional Chinese Medicine, there is no name of atherosclerosis. But, according ...Atherosclerosis (As) is a common disease, also the pathological basis of many cardiovascular diseases and cephalovascular diseases. In Traditional Chinese Medicine, there is no name of atherosclerosis. But, according to its pathological changes, atherosclerosis belongs to the range of “hemostasis”“phlegm-block”“masses and clumps” and so on. Many Chinese Medicinal and formulas can resist atherosclerosis from following aspects:(1) improving the metabolism of apolipoprotein (Apo); (2) inhibiting platelets function, regulating the balance of Prostaglandin I 2(PGI 2)/Thromboxane A 2(TXA 2);(3) increasing the activity of superoxidase, inhibiting the superoxidation of lipoid, protecting vascular endothelial cells (ECs); (4) inhabiting the proliferation of vascular smooth muscle cells (SMCs); (5) regulating the express of activating polypeptides and genes pertaining to atherosclerosis. In this article, we make a summary of them.展开更多
文摘Atherosclerosis (As) is a common disease, also the pathological basis of many cardiovascular diseases and cephalovascular diseases. In Traditional Chinese Medicine, there is no name of atherosclerosis. But, according to its pathological changes, atherosclerosis belongs to the range of “hemostasis”“phlegm-block”“masses and clumps” and so on. Many Chinese Medicinal and formulas can resist atherosclerosis from following aspects:(1) improving the metabolism of apolipoprotein (Apo); (2) inhibiting platelets function, regulating the balance of Prostaglandin I 2(PGI 2)/Thromboxane A 2(TXA 2);(3) increasing the activity of superoxidase, inhibiting the superoxidation of lipoid, protecting vascular endothelial cells (ECs); (4) inhabiting the proliferation of vascular smooth muscle cells (SMCs); (5) regulating the express of activating polypeptides and genes pertaining to atherosclerosis. In this article, we make a summary of them.