睡眠障碍是围绝经期女性常见症状之一,临床表现为入睡困难,夜间觉醒次数增多,睡眠质量下降等。非药物疗法治疗围绝经期睡眠障碍的方法有针灸、穴位贴敷、穴位埋线等中医外治法、心理疗法、运动疗法等,上述疗法治疗围绝经期睡眠障碍的疗...睡眠障碍是围绝经期女性常见症状之一,临床表现为入睡困难,夜间觉醒次数增多,睡眠质量下降等。非药物疗法治疗围绝经期睡眠障碍的方法有针灸、穴位贴敷、穴位埋线等中医外治法、心理疗法、运动疗法等,上述疗法治疗围绝经期睡眠障碍的疗效较为明确。其中中医外治法可单独或与药物等常规方法联合应用,具有整体调节的特色诊疗优势,心理疗法对医师专业技能要求较高。目前关于非药物疗法围绝经期睡眠障碍的研究多以观察临床疗效为主,少见作用机制探讨及大样本临床研究,相关疗法临床操作规范化也有待进一步研究。Sleep disorder is one of the common symptoms of perimenopause women, which is clinically manifested as difficulty in falling sleep, increasing number of night awakneings, and decreasing sleep quality. Non-drug therapy for perimenopausal sleep disorders include acupuncture and moxibustion, acupoint application, acupoint embedding and other external treatment of traditional Chinese medicine, psychotherapy, exercise therapy, etc. The therapeutic effect of the above therapy for perimenopausal sleep disorders is relatively clear. The external treatment of traditional Chinese medicine can be applied alone or in combination with convetional methods such as drugs, which has the characteristics of diagnosis and treatment advantages of overall regulation. Psychological therapy requires high professional skills of physicians. At present, the research on non-drug therapy for perimenopausal sleep disorders mainly focuses on the observation of clinical efficacy, and rarely discusses the mechanism of action and large-scale clinical studies. The standardization of clinical operation of related therapies also needs further research.展开更多
盆腔炎性疾病(PID)是育龄期女性的常见病和多发病,其发病率逐年呈上升趋势。临床上西药治疗有一定的局限性,对没有确定病原体的PID治疗效果不尽如人意,且长期使用抗生素会产生耐药菌,并使双重感染的风险大幅增加。然而,抑制疾病进展和缓...盆腔炎性疾病(PID)是育龄期女性的常见病和多发病,其发病率逐年呈上升趋势。临床上西药治疗有一定的局限性,对没有确定病原体的PID治疗效果不尽如人意,且长期使用抗生素会产生耐药菌,并使双重感染的风险大幅增加。然而,抑制疾病进展和缓解PID长期后遗症的新药需求尚未得到满足,中医药治疗因其副作用少,且治疗慢性病疗效明显而受到广泛关注。近年来,中医药在PID的治疗方面取得了明显进展,而中药单体是中草药中的活性成分,是新药开发的重要来源,为综述中药单体治疗PID的作用机制,本文总结了白芍总苷、金刚藤多糖、白藜芦醇、丹皮酚、连翘提取物、白头翁皂苷B4、菝葜总黄酮、芹菜素、菊苣酸、淫羊藿苷、柴胡皂苷A等在PID治疗过程中的关键环节,以期为临床PID的防治及新药研发提供参考依据和研究方向。Pelvic inflammatory disease (PID) is a common and frequent disease in women of reproductive age, and its incidence is on the rise year by year. Clinical treatment with western drugs has limitations and is unsatisfactory for the treatment of PID without identified pathogens, and the long-term use of antibiotics produces drug-resistant organisms and dramatically increases the risk of double infections. However, there is an unmet need for new drugs to inhibit disease progression and alleviate the long-term sequelae of PID, and TCM treatment has received widespread attention because of its few side effects and its efficacy in treating chronic diseases. In recent years, TCM has made significant progress in the treatment of PID, and TCM monomers, the active ingredients in TCM, are an important source of new drug development. To review the mechanism of action of TCM monomers in the treatment of PID, this paper summarizes the role of Total glucosides of paeonyia, Smilax china L. polysaccharides, resveratrol, paeonol, forsythia suspensa extract, anemoside B4, total flavones of Smilax china L., apigenin, chicoric acid, and icariin, saikosaponin A and other key links in the treatment process of PID, with a view to providing a reference basis and research direction for the prevention and treatment of clinical PID and the development of new drugs.展开更多
多囊卵巢综合征是临床导致育龄期女性不孕最常见的一种生殖内分泌疾病,其发病机制尚不清楚。流行病学调查显示,本病患病率逐年上升,患病群体趋于年轻化,严重影响女性身心健康。白藜芦醇作为一种天然类雌激素,具有降糖降脂、抗炎抗氧化...多囊卵巢综合征是临床导致育龄期女性不孕最常见的一种生殖内分泌疾病,其发病机制尚不清楚。流行病学调查显示,本病患病率逐年上升,患病群体趋于年轻化,严重影响女性身心健康。白藜芦醇作为一种天然类雌激素,具有降糖降脂、抗炎抗氧化、抗肿瘤、心脏保护等多方面药理作用。最近研究发现,白藜芦醇可能通过多途径多靶点影响糖脂代谢及激素调节,这为临床治疗PCOS提供了新思路。笔者结合近几年国内外研究,探讨白藜芦醇对多囊卵巢综合征的调节作用,分析其作用机制,为白藜芦醇在多囊卵巢综合征治疗方面提供进一步的理论基础和研究依据。Polycystic ovary syndrome is the most common reproductive endocrine disease causing infertility in women of childbearing age, and its pathogenesis is still unclear. Epidemiological surveys show that the prevalence of this disease is increasing year by year, and the group of patients tends to be younger, which seriously affects women’s physical and mental health. As a natural estrogen, resveratrol has various pharmacological effects such as hypoglycemic and hypolipidemic, anti-inflammatory and antioxidant, anti-tumor and cardioprotective effects. Recent studies have found that resveratrol may affect glucose-lipid metabolism and hormone regulation through multiple pathways and targets, which provides new ideas for the clinical treatment of PCOS. The author combines domestic and international studies in recent years to explore the regulatory effects of resveratrol on polycystic ovary syndrome (PCOS) and analyze its mechanism of action, so as to provide further theoretical foundation and research basis for resveratrol in the treatment of PCOS.展开更多
经前期综合征(premenstrual syndrome, PMS)是女性在黄体期反复出现周期性以情感、行为和躯体障碍为特征的综合征,为育龄期女性常见的疾病之一,临床常表现为经前头痛背痛、乳房胀痛、失眠、运动协调功能减退、焦虑抑郁等。经前期综合征...经前期综合征(premenstrual syndrome, PMS)是女性在黄体期反复出现周期性以情感、行为和躯体障碍为特征的综合征,为育龄期女性常见的疾病之一,临床常表现为经前头痛背痛、乳房胀痛、失眠、运动协调功能减退、焦虑抑郁等。经前期综合征在育龄期妇女中的发生率约为30%~40%,其中将近三成的女性临床症状较为明显,严重影响女性的身心健康及生活质量,是妇科临床治疗的一大挑战。祖国医学认为,该病属于“经行头痛”、“经行乳房胀痛”等疾病范畴。古代医家对其病因病机及治疗研究深入,早已为现代中医学研究该疾病打下了坚实的基础。肝藏血,主疏泄,调情志,肝气郁结容易导致气滞血瘀,这与PMS的发生和发展密切相关,相关研究表明临床尤以肝郁型PMS较为多见。近年来,运用中医药手段治疗该疾病的研究日趋增多,中医药在治疗过程中较西医治疗发挥着独到优势,且治疗效果显著。本文分别从肝郁型PMS的中医病因病机、内分泌因素的相关研究、中医证候分型及其特点、中医治疗等方面对肝郁型PMS的中医证治研究现状作进一步阐述,以期为中医临床从肝论治经前期综合征提供相关依据及诊疗思路。Premenstrual syndrome (PMS) is a syndrome characterized by emotional, behavioral and somatic disorders that occur repeatedly during the luteal phase of a woman’s life, and is one of the most common illnesses among women of childbearing age. It is often manifested by premenstrual headache and backache, breast swelling and pain, insomnia, loss of motor coordination, anxiety and depression, and so on. The incidence of PMS in women of childbearing age is about 30% to 40%, of which nearly 30% of women have more obvious clinical symptoms, which seriously affects women’s physical and mental health and quality of life, and is a major challenge for gynecological clinical treatment. According to Chinese medicine, this disease belongs to the category of “menstrual headache” and “menstrual breast pain”. Ancient physicians have conducted in-depth research on the etiology, pathogenesis and treatment of this disease, which has long laid a solid foundation for the study of this disease in modern Chinese medicine. The liver stores blood, is the main detoxifier, and regulates emotions, and liver qi stagnation can easily lead to qi stagnation and blood stasis, which is closely related to the occurrence and development of PMS, and relevant studies have shown that liver-depression-type PMS is more common in clinical practice. In recent years, research on the use of traditional Chinese medicine (TCM) in the treatment of this disease has been increasing, and TCM plays a unique advantage over Western medicine in the treatment process, and the therapeutic effect is remarkable. In this paper, we further elaborate on the current status of Chinese medicine treatment of liver-depressed PMS from the aspects of Chinese medicine etiology and pathogenesis of liver-depleted PMS, research on endocrine factors, Chinese medicine symptomatology and its characteristics, Chinese medicine treatment, etc., with a view to providing relevant bases and diagnostic and therapeutic ideas for the treatment of premenstrual syndrome from the theory of liver in the Chinese medicine clinic.展开更多
妊娠期恶心呕吐是孕妇常见病,会对母体和胎儿产生不良影响,可发展为妊娠剧吐,导致不良妊娠结局。近年来,由于穴位贴敷在妊娠期恶心呕吐的治疗中具有效果良好、操作简便安全、可与不同疗法联合应用等优势,被广泛应用于临床。文章就中药...妊娠期恶心呕吐是孕妇常见病,会对母体和胎儿产生不良影响,可发展为妊娠剧吐,导致不良妊娠结局。近年来,由于穴位贴敷在妊娠期恶心呕吐的治疗中具有效果良好、操作简便安全、可与不同疗法联合应用等优势,被广泛应用于临床。文章就中药穴位贴敷的机制及中药穴位贴敷治疗妊娠期恶心呕吐的应用现状进行综述,以期为在不同干预方案下应用中药穴位贴敷治疗妊娠期恶心呕吐提供依据。Nausea and vomiting of pregnancy is a common disease of pregnant women, which will have adverse effects on the mother and fetus and can develop into hyperemesis gravidarum, leading to adverse pregnancy outcomes. In recent years, acupoint application has been widely used in clinics, which has attracted much attention because of its advantages such as good effect, simple and safe operation and combined application with different therapies in the treatment of nausea and vomiting of pregnancy. This paper summarizes the mechanism of acupoint application of traditional Chinese medicine and the application status of acupoint application of traditional Chinese medicine in the treatment of nausea and vomiting of pregnancy, in order to provide a basis of acupoint application of traditional Chinese medicine under different intervention schemes in treating nausea and vomiting of pregnancy.展开更多
文摘睡眠障碍是围绝经期女性常见症状之一,临床表现为入睡困难,夜间觉醒次数增多,睡眠质量下降等。非药物疗法治疗围绝经期睡眠障碍的方法有针灸、穴位贴敷、穴位埋线等中医外治法、心理疗法、运动疗法等,上述疗法治疗围绝经期睡眠障碍的疗效较为明确。其中中医外治法可单独或与药物等常规方法联合应用,具有整体调节的特色诊疗优势,心理疗法对医师专业技能要求较高。目前关于非药物疗法围绝经期睡眠障碍的研究多以观察临床疗效为主,少见作用机制探讨及大样本临床研究,相关疗法临床操作规范化也有待进一步研究。Sleep disorder is one of the common symptoms of perimenopause women, which is clinically manifested as difficulty in falling sleep, increasing number of night awakneings, and decreasing sleep quality. Non-drug therapy for perimenopausal sleep disorders include acupuncture and moxibustion, acupoint application, acupoint embedding and other external treatment of traditional Chinese medicine, psychotherapy, exercise therapy, etc. The therapeutic effect of the above therapy for perimenopausal sleep disorders is relatively clear. The external treatment of traditional Chinese medicine can be applied alone or in combination with convetional methods such as drugs, which has the characteristics of diagnosis and treatment advantages of overall regulation. Psychological therapy requires high professional skills of physicians. At present, the research on non-drug therapy for perimenopausal sleep disorders mainly focuses on the observation of clinical efficacy, and rarely discusses the mechanism of action and large-scale clinical studies. The standardization of clinical operation of related therapies also needs further research.
文摘盆腔炎性疾病(PID)是育龄期女性的常见病和多发病,其发病率逐年呈上升趋势。临床上西药治疗有一定的局限性,对没有确定病原体的PID治疗效果不尽如人意,且长期使用抗生素会产生耐药菌,并使双重感染的风险大幅增加。然而,抑制疾病进展和缓解PID长期后遗症的新药需求尚未得到满足,中医药治疗因其副作用少,且治疗慢性病疗效明显而受到广泛关注。近年来,中医药在PID的治疗方面取得了明显进展,而中药单体是中草药中的活性成分,是新药开发的重要来源,为综述中药单体治疗PID的作用机制,本文总结了白芍总苷、金刚藤多糖、白藜芦醇、丹皮酚、连翘提取物、白头翁皂苷B4、菝葜总黄酮、芹菜素、菊苣酸、淫羊藿苷、柴胡皂苷A等在PID治疗过程中的关键环节,以期为临床PID的防治及新药研发提供参考依据和研究方向。Pelvic inflammatory disease (PID) is a common and frequent disease in women of reproductive age, and its incidence is on the rise year by year. Clinical treatment with western drugs has limitations and is unsatisfactory for the treatment of PID without identified pathogens, and the long-term use of antibiotics produces drug-resistant organisms and dramatically increases the risk of double infections. However, there is an unmet need for new drugs to inhibit disease progression and alleviate the long-term sequelae of PID, and TCM treatment has received widespread attention because of its few side effects and its efficacy in treating chronic diseases. In recent years, TCM has made significant progress in the treatment of PID, and TCM monomers, the active ingredients in TCM, are an important source of new drug development. To review the mechanism of action of TCM monomers in the treatment of PID, this paper summarizes the role of Total glucosides of paeonyia, Smilax china L. polysaccharides, resveratrol, paeonol, forsythia suspensa extract, anemoside B4, total flavones of Smilax china L., apigenin, chicoric acid, and icariin, saikosaponin A and other key links in the treatment process of PID, with a view to providing a reference basis and research direction for the prevention and treatment of clinical PID and the development of new drugs.
文摘多囊卵巢综合征是临床导致育龄期女性不孕最常见的一种生殖内分泌疾病,其发病机制尚不清楚。流行病学调查显示,本病患病率逐年上升,患病群体趋于年轻化,严重影响女性身心健康。白藜芦醇作为一种天然类雌激素,具有降糖降脂、抗炎抗氧化、抗肿瘤、心脏保护等多方面药理作用。最近研究发现,白藜芦醇可能通过多途径多靶点影响糖脂代谢及激素调节,这为临床治疗PCOS提供了新思路。笔者结合近几年国内外研究,探讨白藜芦醇对多囊卵巢综合征的调节作用,分析其作用机制,为白藜芦醇在多囊卵巢综合征治疗方面提供进一步的理论基础和研究依据。Polycystic ovary syndrome is the most common reproductive endocrine disease causing infertility in women of childbearing age, and its pathogenesis is still unclear. Epidemiological surveys show that the prevalence of this disease is increasing year by year, and the group of patients tends to be younger, which seriously affects women’s physical and mental health. As a natural estrogen, resveratrol has various pharmacological effects such as hypoglycemic and hypolipidemic, anti-inflammatory and antioxidant, anti-tumor and cardioprotective effects. Recent studies have found that resveratrol may affect glucose-lipid metabolism and hormone regulation through multiple pathways and targets, which provides new ideas for the clinical treatment of PCOS. The author combines domestic and international studies in recent years to explore the regulatory effects of resveratrol on polycystic ovary syndrome (PCOS) and analyze its mechanism of action, so as to provide further theoretical foundation and research basis for resveratrol in the treatment of PCOS.
文摘经前期综合征(premenstrual syndrome, PMS)是女性在黄体期反复出现周期性以情感、行为和躯体障碍为特征的综合征,为育龄期女性常见的疾病之一,临床常表现为经前头痛背痛、乳房胀痛、失眠、运动协调功能减退、焦虑抑郁等。经前期综合征在育龄期妇女中的发生率约为30%~40%,其中将近三成的女性临床症状较为明显,严重影响女性的身心健康及生活质量,是妇科临床治疗的一大挑战。祖国医学认为,该病属于“经行头痛”、“经行乳房胀痛”等疾病范畴。古代医家对其病因病机及治疗研究深入,早已为现代中医学研究该疾病打下了坚实的基础。肝藏血,主疏泄,调情志,肝气郁结容易导致气滞血瘀,这与PMS的发生和发展密切相关,相关研究表明临床尤以肝郁型PMS较为多见。近年来,运用中医药手段治疗该疾病的研究日趋增多,中医药在治疗过程中较西医治疗发挥着独到优势,且治疗效果显著。本文分别从肝郁型PMS的中医病因病机、内分泌因素的相关研究、中医证候分型及其特点、中医治疗等方面对肝郁型PMS的中医证治研究现状作进一步阐述,以期为中医临床从肝论治经前期综合征提供相关依据及诊疗思路。Premenstrual syndrome (PMS) is a syndrome characterized by emotional, behavioral and somatic disorders that occur repeatedly during the luteal phase of a woman’s life, and is one of the most common illnesses among women of childbearing age. It is often manifested by premenstrual headache and backache, breast swelling and pain, insomnia, loss of motor coordination, anxiety and depression, and so on. The incidence of PMS in women of childbearing age is about 30% to 40%, of which nearly 30% of women have more obvious clinical symptoms, which seriously affects women’s physical and mental health and quality of life, and is a major challenge for gynecological clinical treatment. According to Chinese medicine, this disease belongs to the category of “menstrual headache” and “menstrual breast pain”. Ancient physicians have conducted in-depth research on the etiology, pathogenesis and treatment of this disease, which has long laid a solid foundation for the study of this disease in modern Chinese medicine. The liver stores blood, is the main detoxifier, and regulates emotions, and liver qi stagnation can easily lead to qi stagnation and blood stasis, which is closely related to the occurrence and development of PMS, and relevant studies have shown that liver-depression-type PMS is more common in clinical practice. In recent years, research on the use of traditional Chinese medicine (TCM) in the treatment of this disease has been increasing, and TCM plays a unique advantage over Western medicine in the treatment process, and the therapeutic effect is remarkable. In this paper, we further elaborate on the current status of Chinese medicine treatment of liver-depressed PMS from the aspects of Chinese medicine etiology and pathogenesis of liver-depleted PMS, research on endocrine factors, Chinese medicine symptomatology and its characteristics, Chinese medicine treatment, etc., with a view to providing relevant bases and diagnostic and therapeutic ideas for the treatment of premenstrual syndrome from the theory of liver in the Chinese medicine clinic.
文摘妊娠期恶心呕吐是孕妇常见病,会对母体和胎儿产生不良影响,可发展为妊娠剧吐,导致不良妊娠结局。近年来,由于穴位贴敷在妊娠期恶心呕吐的治疗中具有效果良好、操作简便安全、可与不同疗法联合应用等优势,被广泛应用于临床。文章就中药穴位贴敷的机制及中药穴位贴敷治疗妊娠期恶心呕吐的应用现状进行综述,以期为在不同干预方案下应用中药穴位贴敷治疗妊娠期恶心呕吐提供依据。Nausea and vomiting of pregnancy is a common disease of pregnant women, which will have adverse effects on the mother and fetus and can develop into hyperemesis gravidarum, leading to adverse pregnancy outcomes. In recent years, acupoint application has been widely used in clinics, which has attracted much attention because of its advantages such as good effect, simple and safe operation and combined application with different therapies in the treatment of nausea and vomiting of pregnancy. This paper summarizes the mechanism of acupoint application of traditional Chinese medicine and the application status of acupoint application of traditional Chinese medicine in the treatment of nausea and vomiting of pregnancy, in order to provide a basis of acupoint application of traditional Chinese medicine under different intervention schemes in treating nausea and vomiting of pregnancy.
