目的探讨烧伤合并吸入性损伤患者行机械通气第24小时的氧合指数(OI)对患者预后的影响。方法142例烧伤合并吸入性损伤行机械通气患者,根据第24小时的OI值分为A组[OI≤200 mm Hg(1 mm Hg=0.133 kPa),36例]、B组(200 mm Hg<OI≤300 mm H...目的探讨烧伤合并吸入性损伤患者行机械通气第24小时的氧合指数(OI)对患者预后的影响。方法142例烧伤合并吸入性损伤行机械通气患者,根据第24小时的OI值分为A组[OI≤200 mm Hg(1 mm Hg=0.133 kPa),36例]、B组(200 mm Hg<OI≤300 mm Hg,46例)、C组(OI>300 mm Hg,60例)。比较三组一般资料及预后情况;依据预后情况将患者分为预后不良组(86例)与预后良好组(56例)。采用单因素和多因素Logistic回归分析烧伤合并吸入性损伤机械通气患者预后不良的危险因素。结果三组年龄、烧伤总面积(TBSA)、机械通气前氧分压(PaO_(2))、二氧化碳分压(PaCO_(2))、血氧饱和度(SaO_(2))及预后情况比较,差异具有统计学意义(P<0.05)。C组年龄(40.07±21.20)岁小于A组的(54.64±17.83)岁和B组的(51.72±17.99)岁(P<0.05);B组TBSA(60.43±29.04)%和C组TBSA(62.89±24.85)%小于A组的(74.14±21.90)%,预后不良率54.3%、48.3%低于A组的88.9%(P<0.05)。机械通气前,A组和B组PaO_(2)水平显著低于C组,PaCO_(2)高于C组(P<0.05);B和C组SaO_(2)高于A组(P<0.05)。三组机械通气开始时间、三度烧伤面积及入院延迟复苏情况比较差异无统计学意义(P>0.05)。预后不良组与预后良好组患者的年龄、TBSA、机械通气后第24小时OI比较差异具有统计学意义(P<0.05);预后不良组与预后良好组患者的机械通气开始时间、机械通气时间及机械通气前PaO_(2)、PaCO_(2)、SaO_(2)比较差异无统计学意义(P>0.05)。将筛选出P<0.05的因素纳入多元Logistic回归分析,排除混杂因素后,结果显示:机械通气后第24小时OI≤200 mm Hg、TBSA大、老年是烧伤合并吸入性损伤行机械通气患者预后不良的独立危险因素(OR=5.551、1.046、10.187,P<0.05)。结论机械通气第24小时OI≤200 mm Hg的烧伤合并吸入性损伤患者预后不良,TBSA越大,机械通气前PaO_(2)及SaO_(2)越低,通气后第24小时的OI可能越低。展开更多
Unconventional antiferromagnetism dubbed as altermagnetism was first discovered in rutile structured magnets,which is featured by spin splitting even without the spin–orbital coupling effect.This interesting phenomen...Unconventional antiferromagnetism dubbed as altermagnetism was first discovered in rutile structured magnets,which is featured by spin splitting even without the spin–orbital coupling effect.This interesting phenomenon has been discovered in more altermagnetic materials.In this work,we explore two-dimensional altermagnetic materials by studying two series of two-dimensional magnets,including MF4 with M covering all 3d and 4d transition metal elements,as well as TS2 with T=V,Cr,Mn,Fe.Through the magnetic symmetry operation of RuF4 and MnS2,it is verified that breaking the time inversion is a necessary condition for spin splitting.Based on symmetry analysis and first-principles calculations,we find that the electronic bands and magnon dispersion experience alternating spin splitting along the same path.This work paves the way for exploring altermagnetism in two-dimensional materials.展开更多
文摘目的探讨烧伤合并吸入性损伤患者行机械通气第24小时的氧合指数(OI)对患者预后的影响。方法142例烧伤合并吸入性损伤行机械通气患者,根据第24小时的OI值分为A组[OI≤200 mm Hg(1 mm Hg=0.133 kPa),36例]、B组(200 mm Hg<OI≤300 mm Hg,46例)、C组(OI>300 mm Hg,60例)。比较三组一般资料及预后情况;依据预后情况将患者分为预后不良组(86例)与预后良好组(56例)。采用单因素和多因素Logistic回归分析烧伤合并吸入性损伤机械通气患者预后不良的危险因素。结果三组年龄、烧伤总面积(TBSA)、机械通气前氧分压(PaO_(2))、二氧化碳分压(PaCO_(2))、血氧饱和度(SaO_(2))及预后情况比较,差异具有统计学意义(P<0.05)。C组年龄(40.07±21.20)岁小于A组的(54.64±17.83)岁和B组的(51.72±17.99)岁(P<0.05);B组TBSA(60.43±29.04)%和C组TBSA(62.89±24.85)%小于A组的(74.14±21.90)%,预后不良率54.3%、48.3%低于A组的88.9%(P<0.05)。机械通气前,A组和B组PaO_(2)水平显著低于C组,PaCO_(2)高于C组(P<0.05);B和C组SaO_(2)高于A组(P<0.05)。三组机械通气开始时间、三度烧伤面积及入院延迟复苏情况比较差异无统计学意义(P>0.05)。预后不良组与预后良好组患者的年龄、TBSA、机械通气后第24小时OI比较差异具有统计学意义(P<0.05);预后不良组与预后良好组患者的机械通气开始时间、机械通气时间及机械通气前PaO_(2)、PaCO_(2)、SaO_(2)比较差异无统计学意义(P>0.05)。将筛选出P<0.05的因素纳入多元Logistic回归分析,排除混杂因素后,结果显示:机械通气后第24小时OI≤200 mm Hg、TBSA大、老年是烧伤合并吸入性损伤行机械通气患者预后不良的独立危险因素(OR=5.551、1.046、10.187,P<0.05)。结论机械通气第24小时OI≤200 mm Hg的烧伤合并吸入性损伤患者预后不良,TBSA越大,机械通气前PaO_(2)及SaO_(2)越低,通气后第24小时的OI可能越低。
基金the National Natural Science Foundation of China(Grant No.12004439)Hunan Province Postgraduate Research and Innovation Project(Grant No.CX20230229)the computational resources from the High Performance Computing Center of Central South University.
文摘Unconventional antiferromagnetism dubbed as altermagnetism was first discovered in rutile structured magnets,which is featured by spin splitting even without the spin–orbital coupling effect.This interesting phenomenon has been discovered in more altermagnetic materials.In this work,we explore two-dimensional altermagnetic materials by studying two series of two-dimensional magnets,including MF4 with M covering all 3d and 4d transition metal elements,as well as TS2 with T=V,Cr,Mn,Fe.Through the magnetic symmetry operation of RuF4 and MnS2,it is verified that breaking the time inversion is a necessary condition for spin splitting.Based on symmetry analysis and first-principles calculations,we find that the electronic bands and magnon dispersion experience alternating spin splitting along the same path.This work paves the way for exploring altermagnetism in two-dimensional materials.
