Numerical simulations are performed to examine the packing behavior of human red blood cells(RBCs). A combined ?nite-discrete element method(FDEM) is utilized, in which the RBCs are modeled as no-friction and no-adhes...Numerical simulations are performed to examine the packing behavior of human red blood cells(RBCs). A combined ?nite-discrete element method(FDEM) is utilized, in which the RBCs are modeled as no-friction and no-adhesion solid bodies. The packed volume and the void ratio of a large number of randomly packed RBCs are clari?ed,and the effects of the RBC shape, the mesh size, the cell number, and the container size are investigated. The results show that the packed human RBCs with normal shape have a void ratio of 28.45%, which is slightly higher than that of the ?at or thick cells used in this study. Such information is bene?cial to the further understanding on the geometric features of human RBCs and the research on RBC simulations.展开更多
The combined finiteediscrete element method (FDEM) belongs to a family of methods of computationalmechanics of discontinua. The method is suitable for problems of discontinua, where particles aredeformable and can f...The combined finiteediscrete element method (FDEM) belongs to a family of methods of computationalmechanics of discontinua. The method is suitable for problems of discontinua, where particles aredeformable and can fracture or fragment. The applications of FDEM have spread over a number of disciplinesincluding rock mechanics, where problems like mining, mineral processing or rock blasting canbe solved by employing FDEM. In this work, a novel approach for the parallelization of two-dimensional(2D) FDEM aiming at clusters and desktop computers is developed. Dynamic domain decompositionbased parallelization solvers covering all aspects of FDEM have been developed. These have beenimplemented into the open source Y2D software package and have been tested on a PC cluster. Theoverall performance and scalability of the parallel code have been studied using numerical examples. Theresults obtained confirm the suitability of the parallel implementation for solving large scale problems. 2014 Institute of Rock and Soil Mechanics, Chinese Academy of Sciences. Production and hosting byElsevier B.V. All rights reserved.展开更多
基金Project supported by the Engineering and Physical Sciences Research Council(EPSRC)Turbulence Consortium Grant(No.EP/G069581/1)the Marie Curie International Incoming Fellowship(No.PIIF-GA-253453)
文摘Numerical simulations are performed to examine the packing behavior of human red blood cells(RBCs). A combined ?nite-discrete element method(FDEM) is utilized, in which the RBCs are modeled as no-friction and no-adhesion solid bodies. The packed volume and the void ratio of a large number of randomly packed RBCs are clari?ed,and the effects of the RBC shape, the mesh size, the cell number, and the container size are investigated. The results show that the packed human RBCs with normal shape have a void ratio of 28.45%, which is slightly higher than that of the ?at or thick cells used in this study. Such information is bene?cial to the further understanding on the geometric features of human RBCs and the research on RBC simulations.
文摘The combined finiteediscrete element method (FDEM) belongs to a family of methods of computationalmechanics of discontinua. The method is suitable for problems of discontinua, where particles aredeformable and can fracture or fragment. The applications of FDEM have spread over a number of disciplinesincluding rock mechanics, where problems like mining, mineral processing or rock blasting canbe solved by employing FDEM. In this work, a novel approach for the parallelization of two-dimensional(2D) FDEM aiming at clusters and desktop computers is developed. Dynamic domain decompositionbased parallelization solvers covering all aspects of FDEM have been developed. These have beenimplemented into the open source Y2D software package and have been tested on a PC cluster. Theoverall performance and scalability of the parallel code have been studied using numerical examples. Theresults obtained confirm the suitability of the parallel implementation for solving large scale problems. 2014 Institute of Rock and Soil Mechanics, Chinese Academy of Sciences. Production and hosting byElsevier B.V. All rights reserved.