Antibiotic sensitivity pattern of common bacterial pathogens in NICU and neonatal ward in Hamedan province of Iran

Bacterial pathogens and drug resistance are different in hospitals of each country. In this study we determined bacterial path- ogens and drug sensitivity in the neonatal ward and neonatal intensive care unit (NICU) in Ekbatan hospital in Hamedan. This cross-sectional descriptive study was done on 1150 hospitalized neonates in neonatal and NICU wards of Ekbatan hospital of the Hamadan university of medical sciences from September 2004 to September 2006. Blood, cerebrospinal fluid (CSF), urine, stool, eye excretion, synovial fluid, umbilical secretion and ascitic fluid were evaluated. Positive cultures were evaluated for antibiotic resistance with disk diffusion test methed. All of the data in questionnaires was analyzed with SPSS 13. Cultures including blood, urine, CSF , stool, eye excretion, synovial fluid, umbilical secretion and ascitic fluid was done in 417 neonates (833 cultures). These cultures were including: urine, 323 cases (38.8%) blood 293 cases (35.2%), CSF 180 cases (21.6%) , stool 17 cases (2%), eye secretion 16 cases (1.9%) and other secretions (synovial, umbilical, etc) 4 cases (0.5%). The cultures were positive in 105 cases (25.2%). 60 male neonates (57.1%) and 45 female neonates (42.9%) were culture positive. The most common microorganisms were E coli 66.7% (70 cases), Klebsiella 10.5% (11 cases). Drug resistance was high in these microorganisms. The most common microorganisms were Ecoli and klebsiella. Drug resistance was high in the isolated microorganisms.

Does conventional phototherapy have any effect on platelet count in full term neonates with indirect hyperbilirubinemia?

This study evaluates the platelet count changes in neonates with hyperbillirubinemia who received phototherapy. In this Prospective Descriptive-cross sectional study 144 full term newborns with indirect hyperbillirubinemia who received phototherapy in neonatal ward of Bessat hospital in Hamedan province of Iran were studied from September 2007 to February 2008 for evaluation the effect of phototherapy on platelet count. The platelet had counted by cell counter and it had controlled by slide platelet counting. The data were analyzed using spss version. 13 and compared with paired-samples T test. 58 neonates (40.3%) were boys and 86 (59.7%) were girls. The mean age of neonates was 7.04 +/– 5.49 days (2 - 29 days). The mean (± SD) platelet counts were 287833.3 + 92332.4 before and 299444.4 + 98565.2 after phototherapy. Analysis of data with paired T test showed significant difference in platelet count before and after phototherapy. Mean platelet count after phototherapy was higher than that before treatment. The study had propounded that mean platelet count increased with extended mean phototherapy time. This study had propounded this hypothesis that phototherapy in full term icteric newborns leads to increased platelet count. It may be due to accelerated platelet turnover in peripheral microvasculature with adequate platelet reserve.