Reservoir heterogeneities play a crucial role in governing reservoir performance and management.Traditionally,detailed and inter-well heterogeneity analyses are commonly performed by mapping seismic facies change in t...Reservoir heterogeneities play a crucial role in governing reservoir performance and management.Traditionally,detailed and inter-well heterogeneity analyses are commonly performed by mapping seismic facies change in the seismic data,which is a time-intensive task.Many researchers have utilized a robust Grey-level co-occurrence matrix(GLCM)-based texture attributes to map reservoir heterogeneity.However,these attributes take seismic data as input and might not be sensitive to lateral lithology variation.To incorporate the lithology information,we have developed an innovative impedance-based texture approach using GLCM workflow by integrating 3D acoustic impedance volume(a rock propertybased attribute)obtained from a deep convolution network-based impedance inversion.Our proposed workflow is anticipated to be more sensitive toward mapping lateral changes than the conventional amplitude-based texture approach,wherein seismic data is used as input.To evaluate the improvement,we applied the proposed workflow to the full-stack 3D seismic data from the Poseidon field,NW-shelf,Australia.This study demonstrates that a better demarcation of reservoir gas sands with improved lateral continuity is achievable with the presented approach compared to the conventional approach.In addition,we assess the implication of multi-stage faulting on facies distribution for effective reservoir characterization.This study also suggests a well-bounded potential reservoir facies distribution along the parallel fault lines.Thus,the proposed approach provides an efficient strategy by integrating the impedance information with texture attributes to improve the inference on reservoir heterogeneity,which can serve as a promising tool for identifying potential reservoir zones for both production benefits and fluid storage.展开更多
An optimized combination of gamma alumina (4 wt.%) and strontium (0.1 wt.%) was incorporated in cast Al-20Si alloy to obtain fine form of silicon. During casting process, the amount of γ-Al2O3 was varied from 0.5.6 w...An optimized combination of gamma alumina (4 wt.%) and strontium (0.1 wt.%) was incorporated in cast Al-20Si alloy to obtain fine form of silicon. During casting process, the amount of γ-Al2O3 was varied from 0.5.6 wt.% to refine primary Si and Sr was varied from 0.05.0.1 wt.% to modify eutectic Si. The results showed that the average size of primary Si is 24 μm for addition of 4 wt.%γ-Al2O3 to the alloy whereas 0.1 wt.% Sr resulted in sphericity of eutectic Si to ~0.6 and average length of ~1.2 μm. The thermal analysis revealed that γ-Al2O3 can act as potential heterogeneous nucleation sites. Moreover, simultaneous addition of γ-Al2O3 and Sr does not poison γ-Al2O3 particles and inhibit their nucleation efficiency as in the case of combined addition of phosphorous and strontium to Al-20Si alloy. Therefore, it was concluded that enhanced tensile strength, i.e., ultimate tensile strength (increase by 20%) and elongation (increase by 23%) in Al-20Si.4γ-Al2O3.0.1wt.%Sr alloy as compared to as-cast Al.20Si alloy can be attributed to refinement of primary Si, modification of eutectic Si and the presence of α(Al) in the alloy as evident from eutectic shift.展开更多
The Atlas region in northwest Africa is characterized by the Quaternary volcanism and elevated topography with past complex tectonic mitigation between the African and European plates.Geodynamics of this atypical regi...The Atlas region in northwest Africa is characterized by the Quaternary volcanism and elevated topography with past complex tectonic mitigation between the African and European plates.Geodynamics of this atypical region has left indubitably imprints in crustal architectonics,mainly regarding the crustal thickness as well as the crustal density structure.The knowledge of crustal thickness variations is of a significant interest,since it provides a crucial constraint to geodynamic and geophysical modelling of this region.In this study,we use gravity,topographic,bathymetric and sediment data together with results of seismic surveys to image the Moho topography beneath the Atlas region.The Bouguer gravity anomalies used for a gravimetric Moho recovery are obtained from the free-air gravity anomalies after subtracting the gravitational contributions of topography,bathymetry and sediments.The regional gravimetric Moho inversion constrained on seismic data is carried out by applying a regularized inversion technique based on Gauss-Newton’s formulation of improved Bott’s method,while adopting Earth’s spherical approximation.The numerical result reveals relatively significant Moho depth variations in the Moroccan Atlas,with minima of approximately 24 km along continental margins of the Mediterranean Sea and maxima exceeding 51 km beneath the Rif Cordillera.The Moho depth beneath the West African Craton varies from 32 km in its southern margin to 45 km beneath the Middle Atlas.The Tell Atlas is characterized by the shallow Moho depth of approximately 22 km and further deepening to 42 km towards the northern edge of the Aures Mountains.Our findings indicate a limited tectonic shortening of the High Atlas with the crustal thickness mostly within 36-42 km.Topographic discrepancies between the Rif Cordillera and the Atlas Mountains suggest that the hypothesis of isostatic compensation cannot be fully established.展开更多
In the eastern part of the Indian shield, late Paleozoic-Mesozoic sedimentary rocks of the Talchir Basin lie precisely along a contact of Neoproterozoic age between granulites of the Eastern Ghats Mobile Belt (EGMB)...In the eastern part of the Indian shield, late Paleozoic-Mesozoic sedimentary rocks of the Talchir Basin lie precisely along a contact of Neoproterozoic age between granulites of the Eastern Ghats Mobile Belt (EGMB) and amphibolite facies rocks of the Rengali Province. At present, the northern part of the basin experiences periodic seismicity by reactivation of faults located both within the basin, and in the Rengali Province to the north. Detailed gravity data collected across the basin show that Bouguer anomalies decrease from the EGMB (~+15 mGal), through the basin (^-10 mGal), into the Rengali Province (^-15 mGal). The data are consistent with the reportedly uncompensated nature of the EGMB, and indicate that the crust below the Rengali Province has a cratonic gravity signature. The contact between the two domains with distinct sub-surface structure, inferred from gravity data, coincides with the North Orissa Boundary Fault (NOBF) that defines the northern boundary of the Talchir Basin. Post-Gondwana faults are also localized along the northern margin of the basin, and present-day seismic tremors also have epicenters close to the NOBF. This indicates that the NOBF was formed by reactivation of a Neo- proterozoic terrane boundary, and continues to be susceptible to seismic activity even at the present-day.展开更多
Objective:To investigat the mechanism of antitumor efficacy of Origanum clayi(O.clayi) and Ochradenus baccatus(O.baccatus) extracts by exploring apoptosis-inducing potential.Methods:The aqueous extracts of aerial part...Objective:To investigat the mechanism of antitumor efficacy of Origanum clayi(O.clayi) and Ochradenus baccatus(O.baccatus) extracts by exploring apoptosis-inducing potential.Methods:The aqueous extracts of aerial parts of aforementioned plants were prepared and used for this study.HepG2 cells were treated with varying concentrations(0,2 and 5 mg/mL)of each plant extract for 24 or 48 h.Cell apoptosis was measured by annexin V-fluorescein isothiocyanate binding assay and flow cytometry.The expression levels of various apoptosisrelated genes were determined by semi-quantitative reverse transcription-polymerase chain reaction.Results:O.clayi and O.baccatus extracts exerted apoptotic effects on HepG2 cells for 48 h following treatment.O.clayi extract was found to be a better apoptosis-inducing agent than O.baccatus extract as the former delivered greater efficacy at a lower concentration.Both extracts manifested upregulation of Bax,Bad.cytochrome c.caspase-3,caspase-7.caspase-9 and poly(adenosine diphosphate-ribose) polymerase.Conclusions:The aqueous extracts of O.clayi and O.baccatus are capable of inducing apoptosis in HepG2 cells through modulation of mitochondrial pathway which explains their antitumor activities.These desert plants may serve as useful resources to develop effective remedies for hepatocellular carcinoma and other human malignancies.展开更多
It is estimated that 80% of the world population depends on traditional medicine for primary healthcare need. Trianthema portulacastrum Linn.(family: Aizoaceae) is a small perennial weed found in the Americas, Afri...It is estimated that 80% of the world population depends on traditional medicine for primary healthcare need. Trianthema portulacastrum Linn.(family: Aizoaceae) is a small perennial weed found in the Americas, Africa, India, and other regions of the world. This plant is used extensively in Indian traditional medicines and is also consumed as a vegetable throughout Asia for its perceived health benefits. Phytochemical analysis of T. portulacastrum reveals the presence of alkaloids, fl avonoids, terpenoids, saponins, and phenolic compounds. Emerging studies demonstrate that crude extracts as well as bioactive phytoconstituents of T. portulacastrum exhibit potent antioxidant, anti-infective, analgesic, and anti-infl ammatory activities. A growing number of in vitro and in vivo studies demonstrate various biological and pharmacological activities, including prevention and amelioration of hepatotoxicity, nephrotoxicity, hyperglycemia, hyperlipidemia, infectious diseases and cancer. This review aims to present and analyze available literature to understand the full potential of T. portulacastrum in health promotion and disease prevention. Current limitations and future directions of research on this medicinal and dietary plant are also critically discussed.展开更多
文摘Reservoir heterogeneities play a crucial role in governing reservoir performance and management.Traditionally,detailed and inter-well heterogeneity analyses are commonly performed by mapping seismic facies change in the seismic data,which is a time-intensive task.Many researchers have utilized a robust Grey-level co-occurrence matrix(GLCM)-based texture attributes to map reservoir heterogeneity.However,these attributes take seismic data as input and might not be sensitive to lateral lithology variation.To incorporate the lithology information,we have developed an innovative impedance-based texture approach using GLCM workflow by integrating 3D acoustic impedance volume(a rock propertybased attribute)obtained from a deep convolution network-based impedance inversion.Our proposed workflow is anticipated to be more sensitive toward mapping lateral changes than the conventional amplitude-based texture approach,wherein seismic data is used as input.To evaluate the improvement,we applied the proposed workflow to the full-stack 3D seismic data from the Poseidon field,NW-shelf,Australia.This study demonstrates that a better demarcation of reservoir gas sands with improved lateral continuity is achievable with the presented approach compared to the conventional approach.In addition,we assess the implication of multi-stage faulting on facies distribution for effective reservoir characterization.This study also suggests a well-bounded potential reservoir facies distribution along the parallel fault lines.Thus,the proposed approach provides an efficient strategy by integrating the impedance information with texture attributes to improve the inference on reservoir heterogeneity,which can serve as a promising tool for identifying potential reservoir zones for both production benefits and fluid storage.
文摘An optimized combination of gamma alumina (4 wt.%) and strontium (0.1 wt.%) was incorporated in cast Al-20Si alloy to obtain fine form of silicon. During casting process, the amount of γ-Al2O3 was varied from 0.5.6 wt.% to refine primary Si and Sr was varied from 0.05.0.1 wt.% to modify eutectic Si. The results showed that the average size of primary Si is 24 μm for addition of 4 wt.%γ-Al2O3 to the alloy whereas 0.1 wt.% Sr resulted in sphericity of eutectic Si to ~0.6 and average length of ~1.2 μm. The thermal analysis revealed that γ-Al2O3 can act as potential heterogeneous nucleation sites. Moreover, simultaneous addition of γ-Al2O3 and Sr does not poison γ-Al2O3 particles and inhibit their nucleation efficiency as in the case of combined addition of phosphorous and strontium to Al-20Si alloy. Therefore, it was concluded that enhanced tensile strength, i.e., ultimate tensile strength (increase by 20%) and elongation (increase by 23%) in Al-20Si.4γ-Al2O3.0.1wt.%Sr alloy as compared to as-cast Al.20Si alloy can be attributed to refinement of primary Si, modification of eutectic Si and the presence of α(Al) in the alloy as evident from eutectic shift.
基金conducted under the HK science project 1-ZE8F:Remote-sensing data for studding the Earth’s and planetary inner structure.
文摘The Atlas region in northwest Africa is characterized by the Quaternary volcanism and elevated topography with past complex tectonic mitigation between the African and European plates.Geodynamics of this atypical region has left indubitably imprints in crustal architectonics,mainly regarding the crustal thickness as well as the crustal density structure.The knowledge of crustal thickness variations is of a significant interest,since it provides a crucial constraint to geodynamic and geophysical modelling of this region.In this study,we use gravity,topographic,bathymetric and sediment data together with results of seismic surveys to image the Moho topography beneath the Atlas region.The Bouguer gravity anomalies used for a gravimetric Moho recovery are obtained from the free-air gravity anomalies after subtracting the gravitational contributions of topography,bathymetry and sediments.The regional gravimetric Moho inversion constrained on seismic data is carried out by applying a regularized inversion technique based on Gauss-Newton’s formulation of improved Bott’s method,while adopting Earth’s spherical approximation.The numerical result reveals relatively significant Moho depth variations in the Moroccan Atlas,with minima of approximately 24 km along continental margins of the Mediterranean Sea and maxima exceeding 51 km beneath the Rif Cordillera.The Moho depth beneath the West African Craton varies from 32 km in its southern margin to 45 km beneath the Middle Atlas.The Tell Atlas is characterized by the shallow Moho depth of approximately 22 km and further deepening to 42 km towards the northern edge of the Aures Mountains.Our findings indicate a limited tectonic shortening of the High Atlas with the crustal thickness mostly within 36-42 km.Topographic discrepancies between the Rif Cordillera and the Atlas Mountains suggest that the hypothesis of isostatic compensation cannot be fully established.
文摘In the eastern part of the Indian shield, late Paleozoic-Mesozoic sedimentary rocks of the Talchir Basin lie precisely along a contact of Neoproterozoic age between granulites of the Eastern Ghats Mobile Belt (EGMB) and amphibolite facies rocks of the Rengali Province. At present, the northern part of the basin experiences periodic seismicity by reactivation of faults located both within the basin, and in the Rengali Province to the north. Detailed gravity data collected across the basin show that Bouguer anomalies decrease from the EGMB (~+15 mGal), through the basin (^-10 mGal), into the Rengali Province (^-15 mGal). The data are consistent with the reportedly uncompensated nature of the EGMB, and indicate that the crust below the Rengali Province has a cratonic gravity signature. The contact between the two domains with distinct sub-surface structure, inferred from gravity data, coincides with the North Orissa Boundary Fault (NOBF) that defines the northern boundary of the Talchir Basin. Post-Gondwana faults are also localized along the northern margin of the basin, and present-day seismic tremors also have epicenters close to the NOBF. This indicates that the NOBF was formed by reactivation of a Neo- proterozoic terrane boundary, and continues to be susceptible to seismic activity even at the present-day.
基金Supported by a new faculty start-up research grant(22928)
文摘Objective:To investigat the mechanism of antitumor efficacy of Origanum clayi(O.clayi) and Ochradenus baccatus(O.baccatus) extracts by exploring apoptosis-inducing potential.Methods:The aqueous extracts of aerial parts of aforementioned plants were prepared and used for this study.HepG2 cells were treated with varying concentrations(0,2 and 5 mg/mL)of each plant extract for 24 or 48 h.Cell apoptosis was measured by annexin V-fluorescein isothiocyanate binding assay and flow cytometry.The expression levels of various apoptosisrelated genes were determined by semi-quantitative reverse transcription-polymerase chain reaction.Results:O.clayi and O.baccatus extracts exerted apoptotic effects on HepG2 cells for 48 h following treatment.O.clayi extract was found to be a better apoptosis-inducing agent than O.baccatus extract as the former delivered greater efficacy at a lower concentration.Both extracts manifested upregulation of Bax,Bad.cytochrome c.caspase-3,caspase-7.caspase-9 and poly(adenosine diphosphate-ribose) polymerase.Conclusions:The aqueous extracts of O.clayi and O.baccatus are capable of inducing apoptosis in HepG2 cells through modulation of mitochondrial pathway which explains their antitumor activities.These desert plants may serve as useful resources to develop effective remedies for hepatocellular carcinoma and other human malignancies.
文摘It is estimated that 80% of the world population depends on traditional medicine for primary healthcare need. Trianthema portulacastrum Linn.(family: Aizoaceae) is a small perennial weed found in the Americas, Africa, India, and other regions of the world. This plant is used extensively in Indian traditional medicines and is also consumed as a vegetable throughout Asia for its perceived health benefits. Phytochemical analysis of T. portulacastrum reveals the presence of alkaloids, fl avonoids, terpenoids, saponins, and phenolic compounds. Emerging studies demonstrate that crude extracts as well as bioactive phytoconstituents of T. portulacastrum exhibit potent antioxidant, anti-infective, analgesic, and anti-infl ammatory activities. A growing number of in vitro and in vivo studies demonstrate various biological and pharmacological activities, including prevention and amelioration of hepatotoxicity, nephrotoxicity, hyperglycemia, hyperlipidemia, infectious diseases and cancer. This review aims to present and analyze available literature to understand the full potential of T. portulacastrum in health promotion and disease prevention. Current limitations and future directions of research on this medicinal and dietary plant are also critically discussed.