Because of the great importance of thermal instability in nature, in chemical processes, in separation processes, in industrial applications as well as in geophysical and astrophysical engineering, the effect of therm...Because of the great importance of thermal instability in nature, in chemical processes, in separation processes, in industrial applications as well as in geophysical and astrophysical engineering, the effect of thermal diffusion on the combined MHD heat transfer in an unsteady flow past a continuously moving semi-infinite vertical porous plate which is subjected to constant heat has been investigated numerically under the action of strong applied magnetic field taking into account the induced magnetic field. This study is performed for cooling problem with lighter and heavier particles. Numerical solutions for the velocity field, induced magnetic field as well as temperature distribution are obtained for associated parameters using the explicit finite difference method. The obtained results are also discussed with the help of graphs to observe effects of various parameters on the above mentioned quantities.展开更多
A numerical investigation of boundary layer mass transfer flow through an inclined plate with the effect of chemical reaction and thermal diffusion is presented in this study. The governing partial differential equati...A numerical investigation of boundary layer mass transfer flow through an inclined plate with the effect of chemical reaction and thermal diffusion is presented in this study. The governing partial differential equations (PDE) are transformed to a system of dimensionless non-similar coupled PDEs. The transformed, non-similar conservations equations (momentum balance equation, energy balance equation and concentration balance equation) are then solved using a numerical approach known as explicit finite difference method (EFDM). Basically EFDM introduced for the unsteadiness in the momentum, temperature, and concentration fluid fields is based on the time dependent fluid velocity, temperature and concentration of the boundary surface. During the course of discussion, it is found that the various parameters related to the problem influence the calculated resultant expressions. The computed numerical solution results for the velocity, temperature, and concentration distribution with the effect of various important dimensionless parameters (Grashof number, Modified Grashof number, Prandtl number, Schmidt number, Soret number, Dufour number, chemical reaction parameter and inclination parameter) entering into the problems are critically analyzed and discussed graphically. It can be seen that two physical phenomena chemical reaction and thermal diffusion can greatly effect on the boundary layer fluid flows through an inclined plate.展开更多
Oxidative stress is intensely linked with neurodegenerative disorders, especially Alzheimer’s disease (AD). Searching for medicinal plant with the nootropic activity for controling the development and progression of ...Oxidative stress is intensely linked with neurodegenerative disorders, especially Alzheimer’s disease (AD). Searching for medicinal plant with the nootropic activity for controling the development and progression of AD has received extensive consideration. The plant Phyllanthus reticulatus (PR) Poir. is known in Bengali as Panjuli belongs to family Euphorbiaceae. Previous studies have shown the antioxidant, analgesic, anti-inflammatory, etc. activities of this plant. Therefore, the objective of this study was to examine the nootropic effect of ethanolic extracts of Phyllanthus reticulatus (EEPR) on cognitive functions, brain antioxidatant enzymes and acetylcholinesterase activity in aluminium-induced rats of cognitive impairment and oxidative stress. The effects of EEPR fruit (i.e., 100 and 200 mg/kg b.w.) were examined for 30 days and its nootropic effect was determined in aluminium treated Swiss albino male rats by behavioral studies such as Passive Avoidance (PA) test, Rewarded Alternation (RA) test and biochemical studies such as superoxide dismutase (SOD), catalase (CAT), contents of thiobarbituric acid reactive substances (TBARS) and acetylcholinesterase (AChE) activity in rats brain tissue homogenates. In PA test, administration of EEPR fruit (i.e., 100 and 200 mg/kg, b.w.) significantly (P < 0.05, P < 0.01) increased step-through latency (STL) in rats on 30th day with respect to disease control group. The percentage of memory retention (MR) for this test was pointedly (P < 0.05) increased in rats treated with EEPR fruit (i.e., 200 mg/kg b.w.) as compared with disease control group. For RA test, EEPR fruit (i.e., 200 mg/kg b.w.) markedly (P < 0.01) increased the correct responses (CR) in rats on 30th day related to disease control group. In case of this test the percentage of MR was significantly (P < 0.05, P < 0.01) increased in rats treated with EEPR fruit (i.e., 100 and 200 mg/kg b.w.) with respect to disease control group. Administration of EEPR fruit (i.e., 100 and 200 mg/kg b.w.) considerably (P < 0.05, P < 0.01) increased the level of SOD, CAT and expressively (P < 0.05) decreased TBARS level compared to disease control group. Treatment with EEPR fruit (i.e., 100 and 200 mg/kg b.w.) markedly (P < 0.05, P < 0.01) decreased the level of AChE activity to that of disease control group. The present study shows that EEPR fruit has excellent nootropic effect on cognitive performance and brain antioxidant markers in aluminium-induced rats of cognitive impairment and oxidative stress which could be developed in the management of neurodegenerative diseases especially AD.展开更多
Ensuring food security for the rapidly increasing population and changing climatic scenarios are requisites for exploiting the genetic divergence of food crops.A study was undertaken to sort out an early maturing chic...Ensuring food security for the rapidly increasing population and changing climatic scenarios are requisites for exploiting the genetic divergence of food crops.A study was undertaken to sort out an early maturing chickpea variety for fitting easily between rice-rice cropping systems in the Eastern Indo-Gangetic Plain of Bangladesh.The trial was comprised of eight elite lines of chickpea and executed at various localities in Bangladesh from 2014–15 to 2017–18.The result explored the chickpea genotype,BARI Chola-11 remained superior to the rest of the elite genotypes for having a short maturity period(100–106 days),and lesser days to 50%flowering(47–55 days).The same genotype was recorded to have robust vegetative and reproductive yield attributes including plant height(49–57 cm),podsplant−1(37–50),and optimum 100 seed weight(19.5–20.6 g).Owing to better yield attributes,BARI Chola-11 resulted in the maximum seed yield(1200–1500 kg ha-1)of chickpea and might be recommended for general adoption in the region for boosting nutritional security status through improved productivity under changing climate.展开更多
Background: EEG could be normal or atypical in spite of suggestive clinical features and positive measles Ab of SSPE cases which could have typical EEG pattern after Benzodiazepine. Objectives: The purpose of the pres...Background: EEG could be normal or atypical in spite of suggestive clinical features and positive measles Ab of SSPE cases which could have typical EEG pattern after Benzodiazepine. Objectives: The purpose of the present study was to find out the necessity of administration of benzodiazepine during EEG recording of SSPE cases as well as to compare the efficacy of diazepam and midazolam in eliciting EEG pattern. Methodology: This double blind, parallel, single centered, non-randomized clinical trial was conducted in the Department of Pediatric Neurology at National Institute of Neurosciences, Dhaka, Bangladesh from July 2014 to June 2015 for a period of 1 (one) year. All the clinical and investigational suspected cases of sub-acute Sclerosing Panencephalitis (SSPE) children in both sexes were included as study population. Others neurodegenerative diseases including Wilson’s disease were excluded from this study. Patients were divided into two groups named as group A who were given diazepam and the other group B was given midazolam in IV during EEG recording. The clinical outcomes were measured and were recorded in a pre-designed data sheet. Result: The characteristic typical periodic slow wave complex (PSWC) was found only in 8 (30.8%) patients among the 26 (100.0%) before intervention with benzodiazepines. The remaining 18 (69.2%) had non-typical PSWC of which 10 (38.5%) were normal, 3 (11.5%) with atypical PSWC and 5 (19.2%) were with other EEG findings. After intervention with benzodiazepines, 23 (88.5%) had shown typical PSWC and only 3 (11.5%) had non-typical PSWC. Among the typical PSWC cases after intervention, 8 (30.8%) had normal EEG initially, 5 (19.2%) had other EEG finding, 2 (7.7%) had non-typical PSWC and 8 (30.8%) had typical PSWC from the beginning. Of the 3 (11.5%) of the non-typical PSWC of intervention group, 2 (7.7%) had shown no changes in EEG from the beginning and 1 (3.8%) had shown other EEG finding. The difference between before and after intervention was actually statistically extremely significant (p 0.05). Conclusion: The role of benzodiazepine is very obvious in eliciting the typical EEG pattern in SSPE patients which has shown the characteristic PSWC in EEG in most cases.展开更多
火事件的发生与气候变化以及植被变化密切相关,系统性地研究全新世火活动的时空演化规律,可以更清晰地理解火活动机制与区域性气候、植物变化的关联,同时有助于预测未来火的演化趋势。为了解安达曼海周边地区火灾活动的演化以及可能的...火事件的发生与气候变化以及植被变化密切相关,系统性地研究全新世火活动的时空演化规律,可以更清晰地理解火活动机制与区域性气候、植物变化的关联,同时有助于预测未来火的演化趋势。为了解安达曼海周边地区火灾活动的演化以及可能的驱动因素,以安达曼海南部的海洋钻孔ADM-C1为研究材料,对其全新世以来的炭屑记录进行深入分析,并综合安达曼海周边地区其余的5个炭屑记录,重建了全新世以来安达曼海周边地区火灾活动的演变过程。研究表明,尽管点火、火灾天气和植被组成在各地不尽相同,导致火灾发生频率在区域和地方范围有所不同,但在广泛的气候变化背景下,全新世安达曼海周边各地的火事件发生频率变化具有广泛同步性。全新世安达曼海周边的火灾活动发生频率受到区域性植被和降水变化影响,并最终受控于印度夏季风强度的变化。与末次冰消期相比,12.0~9.0 ka BP安达曼海周边区域火灾活动的发生频率呈下降趋势,反映了印度夏季风降水逐步增加以及木本植物含量逐渐上升的区域环境;9.0~5.0 ka BP较低的区域火灾活动发生频率同时受到较高的印度夏季风降水量和区域木本植物含量的制约;5.0 ka BP后高频的区域火灾活动更多反映了印度夏季风降水的降低。此外,研究结果还表明全新世安达曼海周边区域火灾活动发生频率与厄尔尼诺—南方涛动强度、印度洋偶极子位相和热带辐合带位置的变化相关。展开更多
South Asian(SA)countries have been fighting with the pandemic novel coronavirus disease 2019(COVID-19)since January 2020.Earlier,the country-specific descriptive study has been done.Nevertheless,as transboundary infec...South Asian(SA)countries have been fighting with the pandemic novel coronavirus disease 2019(COVID-19)since January 2020.Earlier,the country-specific descriptive study has been done.Nevertheless,as transboundary infection,the border sharing,shared cultural and behavioral practice,effects on the temporal and spatial distribution of COVID-19 in SA is still unveiled.Therefore,this study has been revealed the spatial hotspot along with descriptive output on different parameters of COVID-19 infection.We extracted data from theWHO and the worldometer database from the onset of the outbreak up to 15 May,2020.Europe has the highest case fatality rate(CFR,9.22%),whereas Oceania has the highest(91.15%)recovery rate from COVID-19.Among SA countries,India has the highest number of cases(85,790),followed by Pakistan(38,799)and Bangladesh(20,065).However,the number of tests conducted was minimum in this region in comparison with other areas.The highest CFR was recorded in India(3.21%)among SA countries,whereas Nepal and Bhutan had no death record due to COVID-19 so far.The recovery rate varies from 4.75%in the Maldives to 51.02%in Sri Lanka.In Bangladesh,community transmission has been recorded,and the highest number of cases were detected in Dhaka,followed by Narayanganj and Chattogram.We detected Dhaka and its surrounding six districts,namely Gazipur,Narsingdi,Narayanganj,Munshiganj,Manikganj,and Shariatpur,as the 99%confidence-based hotspot where Faridpur and Madaripur district as the 95%confidence-based spatial hotspots of COVID-19 in Bangladesh.However,we did not find any cold spots in Bangladesh.We identified three hotspots and three cold spots at different confidence levels in India.Findings from this study suggested the“Test,Trace,and Isolation”approach for earlier detection of infection to prevent further community transmission of COVID-19.展开更多
文摘Because of the great importance of thermal instability in nature, in chemical processes, in separation processes, in industrial applications as well as in geophysical and astrophysical engineering, the effect of thermal diffusion on the combined MHD heat transfer in an unsteady flow past a continuously moving semi-infinite vertical porous plate which is subjected to constant heat has been investigated numerically under the action of strong applied magnetic field taking into account the induced magnetic field. This study is performed for cooling problem with lighter and heavier particles. Numerical solutions for the velocity field, induced magnetic field as well as temperature distribution are obtained for associated parameters using the explicit finite difference method. The obtained results are also discussed with the help of graphs to observe effects of various parameters on the above mentioned quantities.
文摘A numerical investigation of boundary layer mass transfer flow through an inclined plate with the effect of chemical reaction and thermal diffusion is presented in this study. The governing partial differential equations (PDE) are transformed to a system of dimensionless non-similar coupled PDEs. The transformed, non-similar conservations equations (momentum balance equation, energy balance equation and concentration balance equation) are then solved using a numerical approach known as explicit finite difference method (EFDM). Basically EFDM introduced for the unsteadiness in the momentum, temperature, and concentration fluid fields is based on the time dependent fluid velocity, temperature and concentration of the boundary surface. During the course of discussion, it is found that the various parameters related to the problem influence the calculated resultant expressions. The computed numerical solution results for the velocity, temperature, and concentration distribution with the effect of various important dimensionless parameters (Grashof number, Modified Grashof number, Prandtl number, Schmidt number, Soret number, Dufour number, chemical reaction parameter and inclination parameter) entering into the problems are critically analyzed and discussed graphically. It can be seen that two physical phenomena chemical reaction and thermal diffusion can greatly effect on the boundary layer fluid flows through an inclined plate.
文摘Oxidative stress is intensely linked with neurodegenerative disorders, especially Alzheimer’s disease (AD). Searching for medicinal plant with the nootropic activity for controling the development and progression of AD has received extensive consideration. The plant Phyllanthus reticulatus (PR) Poir. is known in Bengali as Panjuli belongs to family Euphorbiaceae. Previous studies have shown the antioxidant, analgesic, anti-inflammatory, etc. activities of this plant. Therefore, the objective of this study was to examine the nootropic effect of ethanolic extracts of Phyllanthus reticulatus (EEPR) on cognitive functions, brain antioxidatant enzymes and acetylcholinesterase activity in aluminium-induced rats of cognitive impairment and oxidative stress. The effects of EEPR fruit (i.e., 100 and 200 mg/kg b.w.) were examined for 30 days and its nootropic effect was determined in aluminium treated Swiss albino male rats by behavioral studies such as Passive Avoidance (PA) test, Rewarded Alternation (RA) test and biochemical studies such as superoxide dismutase (SOD), catalase (CAT), contents of thiobarbituric acid reactive substances (TBARS) and acetylcholinesterase (AChE) activity in rats brain tissue homogenates. In PA test, administration of EEPR fruit (i.e., 100 and 200 mg/kg, b.w.) significantly (P < 0.05, P < 0.01) increased step-through latency (STL) in rats on 30th day with respect to disease control group. The percentage of memory retention (MR) for this test was pointedly (P < 0.05) increased in rats treated with EEPR fruit (i.e., 200 mg/kg b.w.) as compared with disease control group. For RA test, EEPR fruit (i.e., 200 mg/kg b.w.) markedly (P < 0.01) increased the correct responses (CR) in rats on 30th day related to disease control group. In case of this test the percentage of MR was significantly (P < 0.05, P < 0.01) increased in rats treated with EEPR fruit (i.e., 100 and 200 mg/kg b.w.) with respect to disease control group. Administration of EEPR fruit (i.e., 100 and 200 mg/kg b.w.) considerably (P < 0.05, P < 0.01) increased the level of SOD, CAT and expressively (P < 0.05) decreased TBARS level compared to disease control group. Treatment with EEPR fruit (i.e., 100 and 200 mg/kg b.w.) markedly (P < 0.05, P < 0.01) decreased the level of AChE activity to that of disease control group. The present study shows that EEPR fruit has excellent nootropic effect on cognitive performance and brain antioxidant markers in aluminium-induced rats of cognitive impairment and oxidative stress which could be developed in the management of neurodegenerative diseases especially AD.
基金funded by Taif University Researchers Supporting Project No.(TURSP-2020/39),Taif University,Taif,Saudi Arabia.
文摘Ensuring food security for the rapidly increasing population and changing climatic scenarios are requisites for exploiting the genetic divergence of food crops.A study was undertaken to sort out an early maturing chickpea variety for fitting easily between rice-rice cropping systems in the Eastern Indo-Gangetic Plain of Bangladesh.The trial was comprised of eight elite lines of chickpea and executed at various localities in Bangladesh from 2014–15 to 2017–18.The result explored the chickpea genotype,BARI Chola-11 remained superior to the rest of the elite genotypes for having a short maturity period(100–106 days),and lesser days to 50%flowering(47–55 days).The same genotype was recorded to have robust vegetative and reproductive yield attributes including plant height(49–57 cm),podsplant−1(37–50),and optimum 100 seed weight(19.5–20.6 g).Owing to better yield attributes,BARI Chola-11 resulted in the maximum seed yield(1200–1500 kg ha-1)of chickpea and might be recommended for general adoption in the region for boosting nutritional security status through improved productivity under changing climate.
文摘Background: EEG could be normal or atypical in spite of suggestive clinical features and positive measles Ab of SSPE cases which could have typical EEG pattern after Benzodiazepine. Objectives: The purpose of the present study was to find out the necessity of administration of benzodiazepine during EEG recording of SSPE cases as well as to compare the efficacy of diazepam and midazolam in eliciting EEG pattern. Methodology: This double blind, parallel, single centered, non-randomized clinical trial was conducted in the Department of Pediatric Neurology at National Institute of Neurosciences, Dhaka, Bangladesh from July 2014 to June 2015 for a period of 1 (one) year. All the clinical and investigational suspected cases of sub-acute Sclerosing Panencephalitis (SSPE) children in both sexes were included as study population. Others neurodegenerative diseases including Wilson’s disease were excluded from this study. Patients were divided into two groups named as group A who were given diazepam and the other group B was given midazolam in IV during EEG recording. The clinical outcomes were measured and were recorded in a pre-designed data sheet. Result: The characteristic typical periodic slow wave complex (PSWC) was found only in 8 (30.8%) patients among the 26 (100.0%) before intervention with benzodiazepines. The remaining 18 (69.2%) had non-typical PSWC of which 10 (38.5%) were normal, 3 (11.5%) with atypical PSWC and 5 (19.2%) were with other EEG findings. After intervention with benzodiazepines, 23 (88.5%) had shown typical PSWC and only 3 (11.5%) had non-typical PSWC. Among the typical PSWC cases after intervention, 8 (30.8%) had normal EEG initially, 5 (19.2%) had other EEG finding, 2 (7.7%) had non-typical PSWC and 8 (30.8%) had typical PSWC from the beginning. Of the 3 (11.5%) of the non-typical PSWC of intervention group, 2 (7.7%) had shown no changes in EEG from the beginning and 1 (3.8%) had shown other EEG finding. The difference between before and after intervention was actually statistically extremely significant (p 0.05). Conclusion: The role of benzodiazepine is very obvious in eliciting the typical EEG pattern in SSPE patients which has shown the characteristic PSWC in EEG in most cases.
文摘火事件的发生与气候变化以及植被变化密切相关,系统性地研究全新世火活动的时空演化规律,可以更清晰地理解火活动机制与区域性气候、植物变化的关联,同时有助于预测未来火的演化趋势。为了解安达曼海周边地区火灾活动的演化以及可能的驱动因素,以安达曼海南部的海洋钻孔ADM-C1为研究材料,对其全新世以来的炭屑记录进行深入分析,并综合安达曼海周边地区其余的5个炭屑记录,重建了全新世以来安达曼海周边地区火灾活动的演变过程。研究表明,尽管点火、火灾天气和植被组成在各地不尽相同,导致火灾发生频率在区域和地方范围有所不同,但在广泛的气候变化背景下,全新世安达曼海周边各地的火事件发生频率变化具有广泛同步性。全新世安达曼海周边的火灾活动发生频率受到区域性植被和降水变化影响,并最终受控于印度夏季风强度的变化。与末次冰消期相比,12.0~9.0 ka BP安达曼海周边区域火灾活动的发生频率呈下降趋势,反映了印度夏季风降水逐步增加以及木本植物含量逐渐上升的区域环境;9.0~5.0 ka BP较低的区域火灾活动发生频率同时受到较高的印度夏季风降水量和区域木本植物含量的制约;5.0 ka BP后高频的区域火灾活动更多反映了印度夏季风降水的降低。此外,研究结果还表明全新世安达曼海周边区域火灾活动发生频率与厄尔尼诺—南方涛动强度、印度洋偶极子位相和热带辐合带位置的变化相关。
文摘South Asian(SA)countries have been fighting with the pandemic novel coronavirus disease 2019(COVID-19)since January 2020.Earlier,the country-specific descriptive study has been done.Nevertheless,as transboundary infection,the border sharing,shared cultural and behavioral practice,effects on the temporal and spatial distribution of COVID-19 in SA is still unveiled.Therefore,this study has been revealed the spatial hotspot along with descriptive output on different parameters of COVID-19 infection.We extracted data from theWHO and the worldometer database from the onset of the outbreak up to 15 May,2020.Europe has the highest case fatality rate(CFR,9.22%),whereas Oceania has the highest(91.15%)recovery rate from COVID-19.Among SA countries,India has the highest number of cases(85,790),followed by Pakistan(38,799)and Bangladesh(20,065).However,the number of tests conducted was minimum in this region in comparison with other areas.The highest CFR was recorded in India(3.21%)among SA countries,whereas Nepal and Bhutan had no death record due to COVID-19 so far.The recovery rate varies from 4.75%in the Maldives to 51.02%in Sri Lanka.In Bangladesh,community transmission has been recorded,and the highest number of cases were detected in Dhaka,followed by Narayanganj and Chattogram.We detected Dhaka and its surrounding six districts,namely Gazipur,Narsingdi,Narayanganj,Munshiganj,Manikganj,and Shariatpur,as the 99%confidence-based hotspot where Faridpur and Madaripur district as the 95%confidence-based spatial hotspots of COVID-19 in Bangladesh.However,we did not find any cold spots in Bangladesh.We identified three hotspots and three cold spots at different confidence levels in India.Findings from this study suggested the“Test,Trace,and Isolation”approach for earlier detection of infection to prevent further community transmission of COVID-19.