公平且有质量的成人教育观演进——基于七届国际成人教育大会的发展轨迹

联合国教科文组织召开的国际成人教育大会已经举办七届,以七届大会的发展脉络为切入点,对有关成人教育公平的文本进行梳理,挖掘教育公平的发展逻辑。从教育机会部分享有到全体享有、教育公平与质量的统一、从分配正义到承认正义、从统一性到差异性的演进。据此,我国的成人教育建设应该合理配置资源,推进成人教育的均衡发展;融入现代化治理模式,促进共同体建设;建设数字学习环境,打通终身学习立交桥;加强教育公平的社会监督与评价,助力我国建设公平且有质量的成人教育。

High-Performance Anion Exchange Membrane Fuel Cells Enabled by Nitrogen Configuration Optimization in Graphene-Coated Nickel for Enhanced Hydrogen Oxidation

Anion exchange membrane fuel cell(AEMFC)technology is attracting intensive attention,due to its great potential by using non-precious-metal catalysts(NPMCs)in the cathode and cheap bipolar plate materials in alkaline media.However,in such case,the kinetics of hydrogen oxidation reaction(HOR)in the anode is two orders of magnitude sluggish than that of acidic electrolytes,which is recognized as the grand challenge in this field.Herein,we report the rationally designed Ni nanoparticles encapsulated by N-doped graphene layers(Ni@NG)using a facile pyrolysis strategy.Based on the density functional theory calculations and electrochemical performance analysis,it is witnessed that the rich Pyridinic-N within the graphene shell optimizes the binding energy of the intermediates,thus enabling the fundamentally enhanced activity for HOR with robust stability.As a proof of concept,the resultant Ni@NG sample as the anode with a low loading(1.8 mg cm^(-2))in AEMFCs delivers a high peak power density of 500 mW cm^(-2),outperforming all of those of NPMC-based analogs ever reported.

A Room-Temperature Chloride-Conducting Metal-Organic Crystal[Al(DMSO)_(6)]Cl_(3) for Potential Solid-State Chloride-Shuttle Batteries

The growing demand for substitutes of lithium chemistries in battery leads to a surge in budding novel anion-based electrochemical energy storage,where the chloride ion batteries(CIBs)take over the role.The application of CIBs is limited by the dissolution and side reaction of chloride-based electrode materials in a liquid electrolyte.On the flipside,its solid-state electrolytes are scarcely reported due to the challenge in realizing fast Cl^(-)conductivity.The present study reports[Al(DMSO)_(6)]Cl_(3),a solid-state metal-organic material,allows chloride ion transfer.The strong Al-Cl bonds in AlCl_(3)are broken down after coordinating of Al^(3+)by ligand DMSO,and Cl^(-)in the resulting compound is weakly bound to complexions[Al(DMSO)_(6)]^(3+),which may facilitate Cl^(-)migration.By partial replacement of Cl^(-)with PF_(6)^(-),the room-temperature ionic conductivity of as-prepared electrolyte is increased by one order of magnitude from 2.172×10^(-5)S cm^(-1)to 2.012×10^(-4)S cm^(-1).When they are assembled with Ag(anode)/Ag-AgCl(cathode)electrode system,reversible electrochemical redox reactions occur on both sides,demonstrating its potential for solid-state chloride ion batteries.The strategy by weakening the bonding interaction using organic ligands between Cl^(-)and central metallic ions may provide new ideas for developing solid chloride-ion conductors.

The Mediating and Moderating Effects of Family Resilience on the Relationship between Individual Resilience and Depression in Patients with Breast Cancer

Objective:This study evaluated the effect of resilience on depression among patients with breast cancer from individual and familial perspectives by exploring the mediating and moderating effects of family resilience between individual resilience and depression.Methods:A questionnaire survey was conducted among 337 patients with breast cancer who were admitted to the Oncology Department of Jiangsu Province Hospital.The survey included demographic information,the Connor–Davidson Resilience Scale(CD-RISC),the Family Resilience Assessment Scale(FRAS),and the Chinese version of the Patient Health Questionnaire-9(PHQ-9)for Depression.The relationship among individual resilience,family resilience,and depression was analyzed using hierarchical regression and bootstrap test to assess the mediating and moderating effects of family resilience.Results:The depression scores were(13.50±5.16),the individual resilience scores were(48.62±17.50),and the family resilience scores were(105.98±24.35).Significant differences in depression scores were observed in terms of family monthly income,average weekly exercise before diagnosis,post-diagnosis interpersonal relationship quality,and overall sleep quality in the past month(p<0.05).Patients with lower individual resilience had significantly higher depression scores than those with higher resilience(F=24.314,p<0.001),and similarly,patients with lower family resilience had higher depression scores than those with higher family resilience(F=41.660,p<0.001).Individual resilience and family resilience were significantly negatively correlated with depression(r=-0.447 and-0.441,respectively,p<0.001).Hierarchical regression analysis and bootstrap test showed that family resilience(β=-0.310,p<0.001)had a partial mediating effect between individual resilience(β=-0.321,p<0.001)and depression.The indirect effect size was-0.038,the 95%CI was(-0.056,-0.020),and the direct effect ratio was 71.43%.The interaction of family resilience and individual resilience had a moderating effect on depression(B=0.166,p<0.001).Family resilience negatively moderated the relationship between individual resilience and depressive symptoms and enhanced the protective effect of individual resilience against depression with increasing family resilience.Conclusion:Family resilience has mediating and moderating effects between individual resilience and depression in patients with breast cancer.

Effects of foot reflexology on disease

In this article,we review a recently published article to explore the significance of foot reflexology in modern medical practice.With the advancement of modern medicine,we are increasingly committed to finding the specific physiological mechanisms of foot reflexes to treat diseases,thereby better proving the therapy’s effectiveness.It has been reported that foot reflexes can activate the cerebral cor-tex and organs corresponding to the feet,stimulating blood flow,nutrition and nerves through neural and endocrine regulation to achieve the purpose of treating and preventing diseases and promoting health.The therapy shows unique po-tential and value,and provides a new perspective on integrating traditional me-dicine and modern medicine.

Arthroscopic M-shaped suture fixation for tibia avulsion fracture of posterior cruciate ligament:A modified technique and case series

BACKGROUND Tibial avulsion fractures of the posterior cruciate ligament(PCL)are challenging to treat and compromise knee stability and function.Traditional open surgery often requires extensive soft tissue dissection,which may increase the risk of morbidity.In response to these concerns,arthroscopic techniques have been evolving.The aim of this study was to introduce a modified arthroscopic tech-nique utilizing an M-shaped suture fixation method for the treatment of tibial avulsion fractures of the PCL and to evaluate its outcomes through a case series.AIM To evaluate the effects of arthroscopic M-shaped suture fixation on treating tibia avulsion fractures of the PCL.METHODS We developed a modified arthroscopic M-shaped suture fixation technique for tibia avulsion fractures of the PCL.This case series included 18 patients who underwent the procedure between January 2021 and December 2022.The patients were assessed for range of motion(ROM),Lysholm score and International knee documentation committee(IKDC)score.Postoperative complications were also recorded.RESULTS The patients were followed for a mean of 13.83±2.33 months.All patients showed radiographic union.At the final follow-up,all patients had full ROM and a negative posterior drawer test.The mean Lysholm score significantly improved from 45.28±8.92 preoperatively to 91.83±4.18 at the final follow-up(P<0.001),and the mean IKDC score improved from 41.98±6.06 preoperatively to 90.89±5.32 at the final follow-up(P<0.001).CONCLUSION The modified arthroscopic M-shaped suture fixation technique is a reliable and effective treatment for tibia avulsion fractures of the PCL,with excellent fracture healing and functional recovery.

开发和实施现代高等教育的质量保证体系——基于唐山—爱尔兰合作项目的实践和观察（英文）

现代高等教育的质量保证体系对于培养符合现代经济和社会的毕业生起着至关重要的作用。文章提供唐山—爱尔兰合作项目的案例,阐述关于如何开发和实施现代高等教育的质量保证体系的实践和思考。

《Information Systems Research》1998~2017文献计量分析—基于Citespace可视图谱

本文运用Citespace文献计量分析软件,以《Information Systems Research》(简称ISR)期刊在1998年至2017年近20年收录的747篇文献为研究对象,从文献产出分析、国家合作网络分析、机构合作网络分析和引文网络聚类分析四个方面进行研究,研究结果表明:1) 根据文献产出分析,ISR期刊的文献产出量呈现波动性增长;2) 根据国家合作网络分析,美国在国家合作网络中是核心节点,中国需要加强国际合作,提高自身影响力;3) 在研究机构合作网络中,文献产出量前五所高校均位于美国,同时根据合作网络中心性分析,中心性在0.1以上的12所机构中,9所位于美国,中国只有香港城市大学列于其中,另外,德克萨斯大学达拉斯分校、佐治亚理工学院、新加坡国立大学和德克萨斯大学奥斯汀分校,在信息系统领域研究潜力巨大;4) 根据引文网络聚类分析,研究热点的演变可分为三个阶段:1998年至2001年期间信息系统领域研究的重心在信息系统的企业应用,2002年至2011年期间研究重心由传统的组织转移到虚拟组织的测量指标、信任和影响因素,2012年至2017年期间由电子口碑研究转向在线知识社区中的知识扩散研究。

阿柏西普和雷珠单抗治疗糖尿病性黄斑水肿的疗效

目的:比较阿柏西普和雷珠单抗治疗糖尿病性黄斑水肿(DME)的疗效。方法:前瞻性随机对照试验。纳入2020-06/2021-09于我院确诊的非增殖期糖尿病视网膜病变合并DME的患者35例60眼,均采用3+PRN方案行玻璃体腔注射治疗,其中17例30眼接受阿柏西普治疗(阿柏西普组),18例30眼接受雷珠单抗治疗(雷珠单抗组)。随访12mo,观察两组患者中心凹厚度(CMT)和最佳矫正视力(BCVA)情况,记录玻璃体腔注射次数和并发症发生情况。结果:治疗后1、3、6、12mo,阿柏西普组CMT和BCVA均明显优于雷珠单抗组(均P<0.001)。随访期间,阿柏西普组玻璃体腔注射次数少于雷珠单抗组(4.23±0.86次vs 6.40±0.97次,P<0.05),两组患者均未出现药物相关不良反应、眼内感染、血管栓塞等严重并发症。结论:阿柏西普和雷珠单抗治疗DME均具有明确的疗效和安全性,相较于雷珠单抗,阿柏西普可能是DME患者更有效和方便的治疗选择。

Characteristics of Vibration and Sound Radiation of Metro Resilient Wheel

Resilient wheels are extensively used in urban rail transit, especially for tramway systems, owing to its advantages in noise reduction. A new type of resilient wheel for a metro is designed, and its characteristics of vibration and sound radiation, including the rolling noise of a resilient single wheel coupled with a track, are studied in this paper. A two-step research is presented. Firstly, laboratory experiments were conducted to obtain the vibration response of the designed resilient wheel under the radial excitation on its tread. Secondly, the rolling noise model of the resilient wheel coupled with a slab track used in a metro line is developed. The wheel model is based on the 3 D finite elementand boundary element methods and verified by using the experimental results obtained from the laboratory. The track vibration model is based on the wavenumber finite element method, and the track sound radiation is calculatedby using an e cient frequency-domain Rayleigh method. The interaction of the resilient wheel and the slab track is analyzed considering the measured wheel/rail roughness of the metro. The contribution of the resilient wheel to the reduction of wheel/rail system noise is analyzed. The results show that the resilient wheel can e ectively reduce the wheel/rail rolling noise by approximately 2 dB(A) to 3 dB(A), mainly because the radiated noise by the rail is reduced. In addition, the elastic modulus of the rubber has an important influence on the noise reduction of resilient wheels.

贝伐珠单抗玻璃体腔内注射联合复合式小梁切除术治疗NVG的临床观察

目的:观察贝伐珠单抗玻璃体腔内注射联合复合式小梁切除术治疗新生血管性青光眼(neovascular glaucoma,NVG)的疗效。方法:收集2014-01/2016-07我院眼科确诊的NVG患者36例36眼,所有患者均采用贝伐珠单抗玻璃体腔内注射联合丝裂霉素处理的小梁切除术治疗。分别于术前、术后1d(玻璃体腔注射后1d),1、3、6、12mo(小梁切除术后1、3、6、12mo)观察患眼虹膜表面新生血管消退、眼压、视力、滤泡形态、抗青光眼药物使用等情况。结果:随访1a,本组病例手术完全成功26眼,部分成功7眼,失败3眼。术后1、3、6、12mo眼压(18.183±6.993、19.586±6.198、18.722±5.263、19.089±4.133mm Hg)均明显低于术前(39.997±5.827mm Hg)和术后1d(39.647±5.690mm Hg),差异均有统计学意义(P<0.05);术后1、6mo眼压均明显低于术后3mo,差异均有统计学意义(P<0.05);其余术后各时间点眼压两两比较,差异均无统计学意义(P>0.05)。术后1、3、6、12mo Log MAR视力(0.686±0.202、0.622±0.157、0.631±0.179、0.711±0.177)均明显优于术前(0.833±0.207)和术后1d(0.806±0.188),差异均有统计学意义(P<0.05);术后3、6mo Log MAR视力均明显优于术后1mo和术后12mo,差异均有统计学意义(P<0.05)。手术前后使用抗青光眼药物的数量差异有统计学意义(t=11.131,P<0.05)。结论:贝伐珠单抗玻璃体腔内注射联合复合式小梁切除术治疗NVG疗效确切。

Inhibition of TYRO3/Akt signaling participates in hypoxic injury in hippocampal neurons

In this study, we investigated the role of the TYRO3/Akt signaling pathway in hypoxic injury to hippocampal neurons. 3-（4,5-Dimethylthiazol-2-yl）-2,5-diphenyltetrazolium bromide assay showed that hypoxia inhibited the proliferation and viability of hippocampal neurons. Terminal deoxynucleotidyl transferase-mediated d UTP nick end labeling assay demonstrated that hypoxia induced neuronal apoptosis in a time-dependent manner, with a greater number of apoptotic cells with longer hypoxic exposure. Immunofluorescence labeling revealed that hypoxia suppressed TYRO3 expression. Western blot assay showed that hypoxia decreased Akt phosphorylation levels in a time-dependent manner. Taken together, these findings suggest that hypoxia inhibits the proliferation of hippocampal neurons and promotes apoptosis, and that the inhibition of the TYRO3/Akt signaling pathway plays an important role in hypoxia-induced neuronal injury.

Identification of the Interaction between P-Glycoprotein and Anxa2 in Multidrug-resistant Human Breast Cancer Cells

Objective To explore the interaction of Anxa2 with P-Glycoprotein （P-gp） in the migration and invasion of the multidrug-resistant （MDR） human breast cancer cell line MCF-7/ADR. Methods A pair of short hairpin RNA （shRNA） targeting P-gp was transfected into MCF-7/ADR cells, and monoclonal cell strains were screened. The expression of P-gp was detected by Western blot. Transwell chambers were used to observe the cell migration capacity and invasion ability. The interaction between P-gp and Anxa2 was examined by immunoprecipitation and immunofluorescence confocal microscopy analyses. Results P-gp expression was significantly knocked down, and there were notable decreasing trends in the migration and invasion capability of MDR breast cancer cells （P〈0.05）. There was a close interaction between Anxa2 and P-gp. Conclusions MCF-7/ADR is an MDR human breast cancer cell line with high migration and invasion abilities. The knockdown of P-gp notably impaired the migration and invasion abilities of the tumor cells. The interaction of Anxa2 with P-pg may play an important role in time enhanced invasiveness of MDR human breast cancer cells.

Cycle-by-Cycle Queue Length Estimation for Signalized Intersections Using Multi-Source Data

In order to estimate vehicular queue length at signalized intersections accurately and overcome the shortcomings and restrictions of existing studies especially those based on shockwave theory,a new methodology is presented for estimating vehicular queue length using data from both point detectors and probe vehicles. The methodology applies the shockwave theory to model queue evolution over time and space. Using probe vehicle locations and times as well as point detector measured traffic states,analytical formulations for calculating the maximum and minimum( residual) queue length are developed. The proposed methodology is verified using ground truth data collected from numerical experiments conducted in Shanghai,China. It is found that the methodology has a mean absolute percentage error of 17. 09%,which is reasonably effective in estimating the queue length at traffic signalized intersections. Limitations of the proposed models and algorithms are also discussed in the paper.

Numerical Study on the Stress–Strain Cycle of Thermal Self-Compressing Bonding

Thermal self-compressing bonding(TSCB) is a new solid-state bonding method pioneered by the authors. With electron beam as the non-melted heat source, previous experimental study performed on titanium alloys has proved the feasibility of TSCB. However, the thermal stress–strain process during bonding, which is of very important significance in revealing the mechanism of TSCB, was not analysed. In this paper, finite element analysis method is adopted to numerically study the thermal elasto-plastic stress–strain cycle of thermal self-compressing bonding. It is found that due to the localized heating, a non-uniform temperature distribution is formed during bonding, with the highest temperature existed on the bond interface. The expansion of high temperature materials adjacent to the bond interface are restrained by surrounding cool materials and rigid restraints, and thus an internal elasto-plastic stress–strain field is developed by itself which makes the bond interface subjected to thermal compressive action. This thermal self-compressing action combined with the high temperature on the bond interface promotes the atom diffusion across the bond interface to produce solid-state joints. Due to the relatively large plastic deformation, rigid restraint TSCB obtains sound joints in relatively short time compared to diffusion bonding.

Cumene Liquid Oxidation to Cumene Hydroperoxide over CuO Nanoparticle with Molecular Oxygen under Mild Condition

CuO nanoparticle was synthesized via wet chemical method and was characterized diffraction （XRD）, nitrogen adsorption-desorption, and scanning electron microscopy （SEM） by X-ray Catalytic oxidation of cumene with molecular oxygen was studied over CuO nanoparticle. The catalysts showed markedly higher activities as compared to CuO prepared by conventional method, CuO/Al2O3, or homogeneous copper catalyst under comparable reaction conditions. The cumene conversion, cumene hydroperoxide （CHP） yield, and selectivity using 0.25 g CuO nanoparticle catalyst and 0.1 mol cumene at 358 K for 7 h were 44.2%, 41.2% and 93.2%, respectively. The catalyst can be recycled. After 6 recycled experiments, no loss of catalytic activity was observed.

基于特征线—快速傅里叶变换法的轴向柱塞泵流固耦合振动特性研究（英文）

Axial piston pump is fluid-solid coupling mechanical equipment. Its vibration characteristic is compli-cated when working. This paper uses the characteristic line-fast Fourier transform method （MOC - FFT） in theplunger pump to study vibration characteristics caused by fluid-solid coupling. Using the MOC to solve the fluid-solid interaction＇ s （FSI） partial differential equations （ 1 ）, then the vibration characteristics of pipeline system intime domain can be achieved. Using the fast Fourier transform method, the natural frequencies of the piping sys-tem can be obtained. It has the advantage of characteristic line method for the coupling vibration model is clear,easy to calculate; And using the method of fast Fourier transform the vibration characteristics to the frequency do-main. According to study the vibration characteristics in the frequency domain, this paper achieved the frequencywhich the type of A10V pump should be avoided when working and change rules of the angle of swash plate, pres-sure and the speed of rotation how to affect the intensive frequency vibration spectrum which is caused by the FSI.

Effects of Different Spectra from LED on the Growth, Development and Reproduction of Arabidopsis thaliana

Light is the major source of energy for plants and as such has a profound effect on plant growth and development.Red and blue lights have been considered to best drive photosynthetic metabolism and are beneficial for plant growth and development,and green light was seen as a signal to slow down or stop.In this study,Arabidopsis thaliana(Arabidopsis)was used to investigate the effects of red,blue and green lights on the growth and development of plants from seed germination to seeding.Results demonstrated that red light showed a promotion effect but blue light a prohibition one in most stages except for the flowering time in which the effect of each light was just reversed.When mixed with red or blue light,green light generally at least partially cancelled out the effects caused by each of them.Results also showed that the same number of photons the plant received could cause different effects and choosing the right combination of different color of lights is essential in both promoting the growth and development of plants and reducing the energy consumption of lighting in plant factory.

Agronomic cultivation measures on productivity of oilseed flax:A review

Oilseed flax is one of the most important oil crops in China.With the improvement of people's living standards and the deepening knowledge of the nutritional value of oilseed flax,the demand and economic value of oilseed flax are increasing,and the cultivated area in China is expanding.However,the grain yield of oilseed flax is lower than other oil crops.It varies significantly from year to year,combined with a lower degree of mechanization,which has greatly limited the healthy development of the flax industry.Some of the effects of agronomic measures on productivity and water use efficiency of oilseed flax are reviewed in this paper.The major agronomic strategies for the productivity of oilseed flax were presented based on fertilization,plant density,irrigation,cropping pattern and weed control.Future research should investigate the effect of silicon and potassium fertilizers on the mechanism of lodging resistance of oilseed flax,the effects of diversified cropping systems(strip intercropping and crop rotation)on high and stable productivity and efficient utilization of resources.

Experimental Study on the Anti-inflammatory Effect of Ficus pumila L.

[Objectives]To study the anti-inflammatory effects of extracts from different parts of Ficus pumila L.[Methods]Inflammatory models of xylene-induced ear swelling,glacial acetic acid-induced celiac capillary permeability and carrageenan-induced toe swelling were established to evaluate the effects of extracts from different parts of F.pumila L.on inflammation.The inflammatory model of ear swelling in mice with bilateral adrenalectomy induced by xylene was established to determine whether its anti-inflammatory effect depends on hypothalamus-pituitary-adrenal axis(HPAA)system.[Results]Compared with the blank control group,except that there was no statistical significance in the low dose group(P>0.05),the high and middle dose groups of extracts from different parts of F.pumila L.had significant inhibitory effects on xylene-induced ear swelling in mice.The high,middle and low dose groups of F.pumila L.extract could significantly increase the celiac capillary permeability of mice induced by glacial acetic acid,and significantly inhibit the toe swelling induced by carrageenan.Compared with the blank control group,the high and middle dose groups of extracts from different parts of F.pumila L.could significantly inhibit xylene-induced ear swelling and carrageenan-induced toe swelling in bilateral adrenalectomy mice.[Conclusions]The extracts from different parts of F.pumila L.had anti-inflammatory activity,and its anti-inflammatory effect was independent of hypothalamus-pituitary-adrenal axis(HPAA)system.