Ten-Minute Synthesis of a New Redox-Active Aqueous Binder for Flame-Retardant Li-S Batteries

As a critical role in battery systems,polymer binders have been shown to efficiently suppress the lithium polysulfide shuttling and accommodate volume changes in recent years.However,preparation processes and safety,as the key criterions for Li-S batteries'practical applications,still attract less attention.Herein,an aqueous multifunction binder(named PEI-TIC)is prepared via an easy and fast epoxy-amine ring-opening reaction(10 min),which can not only give the sulfur cathode a stable mechanical property,a strong chemical adsorption and catalytic conversion ability,but also a fire safety improvement.The Li-S batteries based on the PEI-TIC binder display a high discharge capacity(1297.8 mAh g^(-1)),superior rate performance(823.0 mAh g^(-1)at 2 C),and an ultralow capacity decay rate of 0.035%over more than 800 cycles.Even under 7.1 mg cm^(-2)S-loaded,the PEI-TIC electrode can also achieve a high areal capacity of 7.2 mA h g^(-1)and excellent cycling stability,confirming its application potential.Moreover,it is also noted that TG-FTIR test is performed for the first time to explore the flame-retardant mechanism of polymer binders.This work provides an economically and environmentally friendly binder for the practical application and inspires the exploration of the flame-retardant mechanism of all electrode components.

A semi-immobilized sulfur-rich copolymer backbone with conciliatory polymer skeleton and conductive substrates for high-performance Li-S batteries

Sulfur-rich polymers have gained a great deal of attention as the next-generation active materials in lithium-sulfur(Li-S)batteries due to their low cost,environmental compatibility,naturally sulfur uniform dispersion,and distinctive structure covalently bonding with sulfur atoms.However,the poor electrical conductivity and undesirable additional shuttle effect still hinder the commercial application of sulfur-rich polymers.Herein,we report a flexible semi-immobilization strategy to prepare allylterminated hyperbranched poly(ethyleneimine)-functionalized reduced graphene oxide(A-PEI-EGO)as sulfur-rich copolymer backbone.The semi-immobilization strategy can effectively reconcile the demand for polymer skeleton and conductive substrates through forming quaternary ammonium groups and reducing oxygen-containing functional groups,resulting in enhanced skeleton adsorption capacity and substrate electronic conductivity,respectively.Furthermore,the stable covalent bonding connection based on polymer molecules(A-PEI)not only completely prevents the additional shuttle effect of lithiation organic molecules and even sulfur-rich oligomers,but provides more inverse vulcanization active sites.As a result,the as-prepared A-PEI-EGO-S cathodes display an initial discharge capacity of1338 m A h g^(-1)at a rate of 0.1 C and an outstanding cycling stability of 0.046%capacity decay per cycle over 600 cycles.Even under 6.2 mg cm^(-2)S-loaded and sparing electrolyte of 6μL mg^(-1),the A-PEI-EGO-S cathode can also achieve a superior cycling performance of 98%capacity retention after 60 cycles,confirming its application potential.

Performance Analysis of Optical Transmission Based on Seven Cores Fiber

This essay designed a kind of new seven-core fiber with lower crosstalk and loss, and made space division multiplexing transmission experiment based on this seven-core fiber. It is known that crosstalk has the most serious influence in multicore fiber transmission process. Before the experiment, the affecting factors of fiber crosstalk were analyzed through simulation, such as core space, bending radius, and fiber length. Combined with the simulation analysis, the design scheme of multicore fiber with low crosstalk was obtained. Before the fiber design, various factors of influence crosstalk such as the core- to-core distance, bending radius, fiber length and so on. Based on the simulation analysis, conclusion has made on the design scheme of multi-core optimal fiber with low crosstalk. The space division multiplexing and wavelength division multiplexing technology, was adopted to conduct seven-core optical fiber transmission of 58.7kin.The crosstalk of adjacent core was suppressed to as low as 45dB / km, the attenuation of inner core was 0.24dB/ km, the outer cores＇ 0.32dB/km. Different bit error rate （BER） performances were also studied under different conditions, through reasonably designing the system to reduce the error rate, improve the performance of the system, and realize long distance and large capacity transmission with fiber.

Effects of different drying methods on drying kinetics and physicochemical properties of Chrysanthemum morifolium Ramat

The effects of infrared-assisted hot-air drying(IR-HAD),temperature,humidity controlled hot-air drying(THC-HAD),and hot-air drying(HAD)on the drying kinetics,physicochemical properties,chlorogenic acid content and microstructure of chrysanthemum were experimentally examined.The results showed that the drying time reduced with increasing air drying temperature,with IR-HAD needing the shortest drying time,followed by THC-HAD and HAD.The effective moisture diffusivities(Deff)of chrysanthemum under IR-HAD,THC-HAD,and HAD at 60℃ were 3.22×10^(-9) m^(2)/s,2.19×10^(-9) m^(2)/s,and 2.89×10^(-9) m^(2)/s,respectively.IR-HAD preserved chrysanthemum surface color better than THC-HAD and HAD,whereas the THC-HAD samples obtained higher water holding capacity(WHC),water binding capacity(WBC),and chlorogenic acid content.Additionally,peroxidase(POD)residual activity of the samples decreased with increasing blanching time.The current work provides a theoretical basis for the drying of chrysanthemum.

Therapeutic application of chick early amniotic fluid: effective rescue of acute myocardial ischemic injury by intravenous administration

Myocardial regeneration has been considered a promising option for the treatment of adult myocardial injuries.Previously,a chick early amniotic fluid(ceAF)preparation was shown to contain growth-related factors that pro-moted embryonic growth and cellular proliferation,though the nature of the components within ceAF were not fully defined.Here we tested whether this ceAF preparation is similarly effective in the promotion of myocardial regen-eration,which could provide an alternative therapeutic for intervening myocardial injury.In this study,a myocardial ischemic injury model was established in adult mice and pigs by multiple research entities,and we were able to show that ceAF can efficiently rescue damaged cardiac tissues and markedly improve cardiac function in both experimental models through intravenous administration.ceAF administration increased cell proliferation and improved angio-genesis,likely via down-regulation of Hippo-YAP signaling.Our data suggest that ceAF administration can effectively rescue ischemic heart injury,providing the key functional information for the further development of ceAF for use in attenuating myocardial injury.

Holistic anti-tumor resistance mechanism of YBX1 and its potential as a chemoresistance target in pancreatic ductal adenocarcinoma

The overall survival rate of pancreatic ductal adenocarcinoma(PDAC)is the worst among all cancers,which is mainly due to the fact that most patients are in the late tumor stage when diagnosed,lacking effective treatment options.Although targeted therapy has shown some prospects in PDAC,its efficacy is limited to patients with specific gene mutation or target gene expression.A large number of patients have no other treatment options except chemotherapy.However,the high drug resistance rate of chemotherapy for PDAC severely limits the improvement of curative effect.Therefore,determining the key factors that lead to drug resistance in PDAC is crucial to improve the prognosis of patients.Multifunctional oncoprotein Y-box binding protein 1(YBX1)may be one of such potential targets.Studies have confirmed that YBX1 is associated with the inherent behavior of a variety of cancers,such as proliferation,invasion,metastasis,and cancer cell stemness.Herein,we integrated and analyzed the resistance mechanism of YBX1 in anti-tumor therapy,and discussed its potential as a therapeutic target to reverse the chemotherapy resistance of PDAC.

Effects of extrusion conditions on the physicochemical properties of soy protein/gluten composite

Soybean protein-gluten blend was extruded using a co-rotating twin-screw extruder.Effects of different extrusion conditions on the textural properties of extrudates were analyzed by central composite design through the evaluation of texturization index,water holding capacity,and hardness of extruded protein products.Extrusion process variables including feed moisture content(40%-60%),screw speed(12-20 Hz),extrusion temperature(120℃-180℃),and gluten content(16%-32%)were studied by the nonlinear regression equations analysis.The extrusion process was also optimized using response surface methodology(RSM).The influence of moisture content on the hardness of extrudate was the most significant.The optimized results,including feed moisture content,extrusion temperature,screw speed and gluten content were 49.18%-50.15%,155.24℃-159.86℃,16.41-16.73 Hz,20.00%-20.03%,respectively.The microstructures of TISP products were analyzed by scanning electron microscopy(SEM)and the changes of protein molecules before and after extrusion were also analyzed by SDS-PAGE electrophoresis.

Activation of Pancreatic Acinar FXR Protects against Pancreatitis via Osginl-Mediated Restoration of Efficient Autophagy

Pancreatitis is the leading cause of hospitalization in gastroenterology,and no medications are available for treating this disease in current clinical practice.FxR plays an anti-inflammatory role in diverse inflammatory diseases,while its function in pancreatitis remains unknown.In this study,we initially observed a marked increase of nuclear FXR in pancreatic tissues of human patients ithpancratis eleting theFXRinpancreati acinar cels FXRicnara/a)ledto moreseverepancreatitis in mousemodels of caerulein-induced acute and chronic pancreatitis,while the FXR agonist GW4064 significantly attenuated pancreatitis in caerulein or arginine-induced acute pancreatitis and caerulein-induced chronic pancreatitis.FXR deletion impaired the viability and stress responses of pancreatic exocrine organoids(PEOs)in vitro.Utilizing RNA-seq and ChIP-seq of PEOs,we identified Osginl as a direct target of FxR in the exocrine pancreas,which was also increasingly expressed in human pancreatitis tissues compared to normal pancreatic tissues.Pancreatic knockdown of Osgin1 by AAV-pan abolished the therapeutic effects of FXR activation on pancreatitis,whereas pancreatic overexpression of Osginl effectively alleviated caerulein-induced pancreatitis.Mechanistically,we found that the FXR-OSGINl axis stimulated autophagic flux in the pancreatic tissues and cell lines,which was considered as the intrinsic mechanisms through which FXR-OSGINI protecting against pancreatitis.Our results highlight the protective role of the FXR-OSGIN1 axis in pancreatitis and provided a new target for the treatment of this disease.