Rock-encased-backfill(RB)structures are common in underground mining,for example in the cut-andfill and stoping methods.To understand the effects of cyclic excavation and blasting activities on the damage of these RB ...Rock-encased-backfill(RB)structures are common in underground mining,for example in the cut-andfill and stoping methods.To understand the effects of cyclic excavation and blasting activities on the damage of these RB structures,a series of triaxial stepwise-increasing-amplitude cyclic loading experiments was conducted with cylindrical RB specimens(rock on outside,backfill on inside)with different volume fractions of rock(VF=0.48,0.61,0.73,and 0.84),confining pressures(0,6,9,and 12 MPa),and cyclic loading rates(200,300,400,and 500 N/s).The damage evolution and meso-crack formation during the cyclic tests were analyzed with results from stress-strain hysteresis loops,acoustic emission events,and post-failure X-ray 3D fracture morphology.The results showed significant differences between cyclic and monotonic loadings of RB specimens,particularly with regard to the generation of shear microcracks,the development of stress memory and strain hardening,and the contact forces and associated friction that develops along the rock-backfill interface.One important finding is that as a function of the number of cycles,the elastic strain increases linearly and the dissipated energy increases exponentially.Also,compared with monotonic loading,the cyclic strain hardening characteristics are more sensitive to rising confining pressures during the initial compaction stage.Another finding is that compared with monotonic loading,more shear microcracks are generated during every reloading stage,but these microcracks tend to be dispersed and lessen the likelihood of large shear fracture formation.The transition from elastic to plastic behavior varies depending on the parameters of each test(confinement,volume fraction,and cyclic rate),and an interesting finding was that the transformation to plastic behavior is significantly lower under the conditions of 0.73 rock volume fraction,400 N/s cyclic loading rate,and 9 MPa confinement.All the findings have important practical implications on the ability of backfill to support underground excavations.展开更多
This study aims to investigate mechanical properties and failure mechanisms of layered rock with rough joint surfaces under direct shear loading.Cubic layered samples with dimensions of 100 mm×100 mm×100 mm ...This study aims to investigate mechanical properties and failure mechanisms of layered rock with rough joint surfaces under direct shear loading.Cubic layered samples with dimensions of 100 mm×100 mm×100 mm were casted using rock-like materials,with anisotropic angle(α)and joint roughness coefficient(JRC)ranging from 15°to 75°and 2-20,respectively.The direct shear tests were conducted under the application of initial normal stress(σ_(n)) ranging from 1-4 MPa.The test results indicate significant differences in mechanical properties,acoustic emission(AE)responses,maximum principal strain fields,and ultimate failure modes of layered samples under different test conditions.The peak stress increases with the increasingαand achieves a maximum value atα=60°or 75°.As σ_(n) increases,the peak stress shows an increasing trend,with correlation coefficients R² ranging from 0.918 to 0.995 for the linear least squares fitting.As JRC increases from 2-4 to 18-20,the cohesion increases by 86.32%whenα=15°,while the cohesion decreases by 27.93%whenα=75°.The differences in roughness characteristics of shear failure surface induced byαresult in anisotropic post-peak AE responses,which is characterized by active AE signals whenαis small and quiet AE signals for a largeα.For a given JRC=6-8 andσ_(n)=1 MPa,asαincreases,the accumulative AE counts increase by 224.31%(αincreased from 15°to 60°),and then decrease by 14.68%(αincreased from 60°to 75°).The shear failure surface is formed along the weak interlayer whenα=15°and penetrates the layered matrix whenα=60°.Whenα=15°,as σ_(n) increases,the adjacent weak interlayer induces a change in the direction of tensile cracks propagation,resulting in a stepped pattern of cracks distribution.The increase in JRC intensifies roughness characteristics of shear failure surface for a smallα,however,it is not pronounced for a largeα.The findings will contribute to a better understanding of the mechanical responses and failure mechanisms of the layered rocks subjected to shear loads.展开更多
Flexible and wearable pressure sensors hold immense promise for health monitoring,covering disease detection and postoperative rehabilitation.Developing pressure sensors with high sensitivity,wide detection range,and ...Flexible and wearable pressure sensors hold immense promise for health monitoring,covering disease detection and postoperative rehabilitation.Developing pressure sensors with high sensitivity,wide detection range,and cost-effectiveness is paramount.By leveraging paper for its sustainability,biocompatibility,and inherent porous structure,herein,a solution-processed all-paper resistive pressure sensor is designed with outstanding performance.A ternary composite paste,comprising a compressible 3D carbon skeleton,conductive polymer poly(3,4-ethylene dioxythiophene):poly(styrenesulfonate),and cohesive carbon nanotubes,is blade-coated on paper and naturally dried to form the porous composite electrode with hierachical micro-and nano-structured surface.Combined with screen-printed Cu electrodes in submillimeter finger widths on rough paper,this creates a multiscale hierarchical contact interface between electrodes,significantly enhancing sensitivity(1014 kPa-1)and expanding the detection range(up to 300 kPa)of as-resulted all-paper pressure sensor with low detection limit and power consumption.Its versatility ranges from subtle wrist pulses,robust finger taps,to large-area spatial force detection,highlighting its intricate submillimetermicrometer-nanometer hierarchical interface and nanometer porosity in the composite electrode.Ultimately,this all-paper resistive pressure sensor,with its superior sensing capabilities,large-scale fabrication potential,and cost-effectiveness,paves the way for next-generation wearable electronics,ushering in an era of advanced,sustainable technological solutions.展开更多
As a sister compound of PbTe, SnTe possesses the environmentally friendly elements. However, the pristine SnTe compounds suffer from the high carrier concentration, the large valence band offset between the L and Σpo...As a sister compound of PbTe, SnTe possesses the environmentally friendly elements. However, the pristine SnTe compounds suffer from the high carrier concentration, the large valence band offset between the L and Σpositions and high thermal conductivity. Using high-pressure and high-temperature technology, we synthesized the pristine SnTe samples at different pressures and systemically investigated their thermoelectric properties.High pressure induces rich microstructures, including the high-density dislocations and lattice distortions, which serve as the strong phonon scattering centers, thereby reducing the lattice thermal conductivity. For the electrical properties, pressure reduces the harmful high carrier concentration, due to the depression of Sn vacancies.Moreover, pressure induces the valence band convergence, reducing the energy separation between the L and Σpositions. The band convergence and suppressed carrier concentration increase the Seebeck coefficient. Thus, the power factors of pressure-sintered compounds do not deteriorate significantly under the condition of decreasing electrical conductivity. Ultimately, for a pristine SnTe compound synthesized at 5 GPa, a higher ZT value of 0.51 is achieved at 750 K, representing a 140% improvement compared to the value of 0.21 obtained using SPS. Therefore, the high-pressure and high-temperature technology is demonstrated as an effectively approach to optimize thermoelectric performance.展开更多
Defects in graphene can profoundly impact its extraordinary properties,ultimately influencing the performances of graphene-based nanodevices.Methods to detect defects with atomic resolution in graphene can be technica...Defects in graphene can profoundly impact its extraordinary properties,ultimately influencing the performances of graphene-based nanodevices.Methods to detect defects with atomic resolution in graphene can be technically demanding and involve complex sample preparations.An alternative approach is to observe the thermal vibration properties of the graphene sheet,which reflects defect information but in an implicit fashion.Machine learning,an emerging data-driven approach that offers solutions to learning hidden patterns from complex data,has been extensively applied in material design and discovery problems.In this paper,we propose a machine learning-based approach to detect graphene defects by discovering the hidden correlation between defect locations and thermal vibration features.Two prediction strategies are developed:an atom-based method which constructs data by atom indices,and a domain-based method which constructs data by domain discretization.Results show that while the atom-based method is capable of detecting a single-atom vacancy,the domain-based method can detect an unknown number of multiple vacancies up to atomic precision.Both methods can achieve approximately a 90%prediction accuracy on the reserved data for testing,indicating a promising extrapolation into unseen future graphene configurations.The proposed strategy offers promising solutions for the non-destructive evaluation of nanomaterials and accelerates new material discoveries.展开更多
A novel real time fast electron bremsstrahlung (FEB) diagnostic system based on the lutetium yttrium oxyorthosilicate scintillators (LYSO) and silicon photomultipliers (SiPM) has been developed for tokamak.The diagnos...A novel real time fast electron bremsstrahlung (FEB) diagnostic system based on the lutetium yttrium oxyorthosilicate scintillators (LYSO) and silicon photomultipliers (SiPM) has been developed for tokamak.The diagnostic system is dedicated to study the FEB emission in the hard x-ray (HXR) energy range between 10 and 200 keV during the lower hybrid current drive.The system consists of a detection module and three data acquisition and processing (DAP)boards.The detection module consists of annulus LYSO-SiPM detector array and a 12-channel preamplifier module.The DAP boards upload the data to the host computer for displaying and storing through PXI bus.The time and space resolutions of the system are 10 ms and 4 cm,respectively.The experimental results can show the evolution over time and the spatial distribution of FEB.This paper presents the system performance and typical discharge results.展开更多
Discontinuities are often considered as important factors responsible for the instability caused by shear failure in engineering rock mass,and energy-driven instability is the root cause of rock failure.However,few st...Discontinuities are often considered as important factors responsible for the instability caused by shear failure in engineering rock mass,and energy-driven instability is the root cause of rock failure.However,few studies focus on the energy evolution during the failure process using a three-dimensional(3D)numerical model.In this study,a series of laboratory direct shear tests on rock-like samples is numer-ically simulated using bonded particle models(BPMs)with multiple combinations of discontinuous in the particle flow code(PFC3D),in which the location and size of the particles conform to the uniform distribution.The effects of joint row number and inclination on the stress-strain characteristics and failure mode of rock were studied from the perspective of microcrack growth and energy evolution.The results showed that,when the number of joint rows Nr>1,the shear failure region does not change with the increase of Nr for the type B(2-columnn multiple-row at center)and the type C(2-column multiple-row at edge)as compared to the type A(1-column multiple-row at center)joint models.Notably,joints significantly increase the post-peak energy dissipation but have little effect on the proportion of energy before the peak.Friction consumes most of the energy while kinetic energy accounts for less than 1%of total energy during the shear process.Peak elastic strain energy follows the variation trend of peak shear displacement.The development and accumulation of microcracks directly affect the energy dissipation,and there is a significant linear relationship between the cumulative number of critical microcracks and the critical dissipated energy at the failure,when the dip direction of joints is opposite to the shear direction,more microcracks will be accumulated at the peak time,resulting in more energy dissipation.The results contribute to deeply understanding the shear failure process of non-persistent jointed mass.展开更多
Vicatia thibetica de Boiss is a Tibetan medicinal herb and mainly contains chemical components such as flavonoids,β-sitosterol and ferulic acid.It has good pharmacological effects such as anti-inflammatory,analgesic,...Vicatia thibetica de Boiss is a Tibetan medicinal herb and mainly contains chemical components such as flavonoids,β-sitosterol and ferulic acid.It has good pharmacological effects such as anti-inflammatory,analgesic,anti-fatigue,anti-oxidation,anti-aging and enhancing immunity.Based on relevant domestic and foreign literature,this paper comprehensively reviews the main components,pharmacological activity and clinical prescription application of V.thibetica de Boiss,to provide a reference for the in-depth research and comprehensive development and utilization of V.thibetica de Boiss.展开更多
A digital pulse analysis system is an important diagnostic system in nuclear physics experimental research.In response to the demand for reflecting the particle state in a nuclear physics experiment,we have designed a...A digital pulse analysis system is an important diagnostic system in nuclear physics experimental research.In response to the demand for reflecting the particle state in a nuclear physics experiment,we have designed and developed a real-time digital pulse analysis system and applied it to the digital nuclear pulse waveform discrimination of different detectors in the HL-2M tokamak.The system is based on the peripheral component interconnect extensions for instrumentation(PXI)platform,while its software was written in LABVIEW.The key technologies involved in the system implementation include digital pulse analysis technology,digital discrimination technology,pulse height analysis technology,etc.The system has been applied to the plastic scintillator detector at the Neutron Source Lab of the University of Science and Technology of China.And the experimental results indicate that the system can discriminate between neutron(n)particles and gamma(γ)particles well when used to measure the plastic scintillator detector.展开更多
We propose the Forward-Backward Synergistic Acceleration Pursuit (FBSAP) algorithm in this paper. The FBSAP algorithm inherits the advantages of the Forward-Backward Pursuit (FBP) algorithm, which has high success rat...We propose the Forward-Backward Synergistic Acceleration Pursuit (FBSAP) algorithm in this paper. The FBSAP algorithm inherits the advantages of the Forward-Backward Pursuit (FBP) algorithm, which has high success rate of reconstruction and does not necessitate the sparsity level as a priori condition. Moreover, it solves the problem of FBP that the atom can be selected only by the fixed step size. By mining the correlation between candidate atoms and residuals, we innovatively propose the forward acceleration strategy to adjust the forward step size adaptively and reduce the computation. Meanwhile, we accelerate the algorithm further in backward step by fusing the strategy proposed in Acceleration Forward-Backward Pursuit (AFBP) algorithm. The experimental simulation results demonstrate that FBSAP can greatly reduce the running time of the algorithm while guaranteeing the success rate in contrast to FBP and AFBP.展开更多
Image-guided thermal ablation(TA),which is less invasive,has been widely applied for treating various kinds of tumors.However,TA still poses the potential risk of thermal damage to sensitive tissue nearby.Therefore,an...Image-guided thermal ablation(TA),which is less invasive,has been widely applied for treating various kinds of tumors.However,TA still poses the potential risk of thermal damage to sensitive tissue nearby.Therefore,an adjunctive thermoprotective hydrodissection technique with constant injection of 5%glucose(5%Glu)has currently been adopted for clinical application,but this may be hazardous to humans.In this study,a multifunctional hyaluronic acid-based hydrogel(HA-Dc)was developed for hydrodissection.Compared with 5%Glu(the most clinically used solution)and the previously reported F127 hydrogel,the HA-Dc hydrogel was studied in vitro in a porcine liver model and in vivo in a rabbit model and showed good injectability and better tissue retention,stability,and thermoprotective properties throughout the TA procedure.Furthermore,in the preclinical evaluation in a Macaca fascicularis(M.fascicularis)model,HA-Dc showed excellent performance in terms of stricter neuroprotection compared with 5%Glu.In addition,the HA-Dc hydrogel with good biocompatibility and controllable degradation behavior in vivo could be a promising platform for thermal protection during clinical TA procedures.展开更多
316L stainless steel(SS)is widely applied as microimplant anchorage(MIA)due to its excellent mechanical properties.However,the risk that the oral microorganisms can corrode 316L SS is fully neglected.Microbiologically...316L stainless steel(SS)is widely applied as microimplant anchorage(MIA)due to its excellent mechanical properties.However,the risk that the oral microorganisms can corrode 316L SS is fully neglected.Microbiologically influenced corrosion(MIC)of 316L SS is essential to the health and safety of all patients because the accelerated corrosion caused by the oral microbiota can trigger the release of Cr and Ni ions.This study investigated the corrosion behavior and mechanism of subgingival microbiota on 316L SS by 16S rRNA and metagenome sequencing,electrochemical measurements,and surface characterization techniques.Multispecies biofilms were formed by the oral subgingival microbiota in the simulated oral anaerobic environment on 316L SS surfaces,significantly accelerating the corrosion in the form of pitting.The microbiota samples collected from the subjects differed in biofilm compositions,corrosion behaviors,and mechanisms.The oral subgingival microbiota contributed to the accelerated corrosion of 316L SS via acidic metabolites and extracellular electron transfer.Our findings provide a new insight into the underlying mechanisms of oral microbial corrosion and guide the design of oral microbial corrosion-resistant materials.展开更多
The influence of different types of roots on the soil is complex and still remains unclear.Four in-situ extrusion tests were conducted on two types of root systems,namely fibrous and tap root system,for three plants,E...The influence of different types of roots on the soil is complex and still remains unclear.Four in-situ extrusion tests were conducted on two types of root systems,namely fibrous and tap root system,for three plants,Eleusine indica,Potentilla anserine,and Artemisia argyi,according to the classification in Botany,and the thrust-displacement curves and failure patterns of different samples were analysed by comparison to fill the aforementioned gap.Results reveal that the roots can reduce the characteristics of soil brittleness and enhance its capability to resist large deformation,and different root types contribute different effects to the strain-hardening behavior of the root-soil mass.The contribution of the fibrous root system to strength is limited,whilst the tap root system substantially enhances strength and stiffness.Results of failure patterns show that fibrous and tap root systems affect soil solidification and surface cracking reduction.However,the effect of the tap root system depends on the composition of lateral and tap roots:long and rich lateral roots are effective for resisting the creation of cracks,but thick tap roots with few and thin lateral roots may lead to several surface cracks.展开更多
In this work,the Al-Cu-Mg alloy with different Y(0-0.2 wt%)and Ce(0.5-1.5 wt%)are designed.The effect of mixed addition of Y and Ce on the grain structure and hot tearing for Al-4.4Cu-1.5Mg-0.15Zr alloy was investigat...In this work,the Al-Cu-Mg alloy with different Y(0-0.2 wt%)and Ce(0.5-1.5 wt%)are designed.The effect of mixed addition of Y and Ce on the grain structure and hot tearing for Al-4.4Cu-1.5Mg-0.15Zr alloy was investigated using"cross"hot tearing mould.The results indicate that as rare earth Y and Ce increases,the grain size becomes finer,the grain morphology changes from dendrite to equiaxed grain,and effectively reduce the hot tearing sensitivity coefficient(HTS1)and crack susceptibility coefficient(CSC)of the alloy.With the increase of Ce element(0.5-1.5 wt%),the hot tearing susceptibility of the alloy decreases first and then increases.With the increase of Y element(0-0.2 wt%),the hot tearing sensitivity of the alloy decreases.When the content of rare earth is 0.2 wt%Y+1.0 wt%Ce,the minimum HTS1 value and CSC value of the alloy are 68 and 0.53,respectively.Rare earth Ce refines the alloy microstructure,shortens the feeding channel,and reduces the hot tearing initiation.Meanwhile,the rare earth Y can form Al6Cu6Y phase at the grain boundary,improve the feeding capacity of the alloy.Therefore,appropriate addition of rare earth Y and Ce can effectively reduce the hot tearing tendency of the alloy.展开更多
Pulmonary fibrosis (PF) is a chronic progressive end-stage lung disease. However, the mechanisms underlying the progression of this disease remain elusive. Presently, clinically employed drugs are scarce for the treat...Pulmonary fibrosis (PF) is a chronic progressive end-stage lung disease. However, the mechanisms underlying the progression of this disease remain elusive. Presently, clinically employed drugs are scarce for the treatment of PF. Hence, there is an urgent need for developing novel drugs to address such diseases. Our study found for the first time that a natural source of Prismatomeris connata Y. Z. Ruan (Huang Gen, HG) ethyl acetate extract (HG-2) had a significant anti-PF effect by inhibiting the expression of the transforming growth factor beta 1/suppressor of mothers against decapentaplegic (TGF-β1/Smad) pathway. Network pharmacological analysis suggested that HG-2 had effects on tyrosine kinase phosphorylation, cellular response to reactive oxygen species, and extracellular matrix (ECM) disassembly. Moreover, mass spectrometry imaging (MSI) was used to visualize the heterogeneous distribution of endogenous metabolites in lung tissue and reveal the anti-PF metabolic mechanism of HG-2, which was related to arginine biosynthesis and alanine, asparate and glutamate metabolism, the downregulation of arachidonic acid metabolism, and the upregulation of glycerophospholipid metabolism. In conclusion, we elaborated on the relationship between metabolite distribution and the progression of PF, constructed the regulatory metabolic network of HG-2, and discovered the multi-target therapeutic effect of HG-2, which might be conducive to the development of new drugs for PF.展开更多
In modern Wi-Fi systems,channel state information(CSI)serves as a foundational support for various sensing applications.Currently,existing CSI-based techniques exhibit limitations in terms of environmental adaptabilit...In modern Wi-Fi systems,channel state information(CSI)serves as a foundational support for various sensing applications.Currently,existing CSI-based techniques exhibit limitations in terms of environmental adaptability.As such,optimizing the utilization of subcarrier CSI stands as a critical avenue for enhancing sensing performance.Within the OFDM communication framework,this work derives sensing outcomes for both detection and estimation by harnessing the CSI from every individual measured subcarrier,subsequently consolidating these outcomes.When contrasted against results derived from CSI based on specific extraction protocols or those obtained through weighted summation,the methodology introduced in this study offers substantial improvements in CSI-based detection and estimation performance.This approach not only underscores the significance but also serves as a robust exemplar for the comprehensive application of CSI.展开更多
Due to wear and manufacturing tolerance,the freeplay is unavoidable in the hinges of folding fins,which exerts significant effects on the aerodynamic characteristics.This paper proposes a backbone-curve-based framewor...Due to wear and manufacturing tolerance,the freeplay is unavoidable in the hinges of folding fins,which exerts significant effects on the aerodynamic characteristics.This paper proposes a backbone-curve-based framework for the dynamical identification of folding fins containing the freeplay nonlinearity.With no need to measure the input force signal and the response signals of nonlinear related Degrees of Freedom(DOFs),the proposed method is more direct and elegant than most existing nonlinear identification approaches,and it contains three steps:Firstly,the underlying linear model of the folding fin structure is obtained through the modal test on its linear sub-parts,and then,the harmonic approximation solves the analytical expressions of the backbone curves of measurable DOFs.Secondly,response data measured from the sine-sweep test are used to extract the fitting points of backbone curves for these DOFs.Finally,the curve fitting approach is applied to identify the freeplay parameters.A series of numerical experiments verify the effectiveness of the proposed method.A real-life folding fin structure is also employed to illustrate how the method can be applied.These examples demonstrate that the identification framework can give an accurate dynamic model of the folding fin structure.展开更多
In the past few years,supercapacitors(SCs)have attracted great attention in both academic and industrial sectors due to their high energy storage efficiency,reliable stability,and eco-friendly process.Flexible solid-s...In the past few years,supercapacitors(SCs)have attracted great attention in both academic and industrial sectors due to their high energy storage efficiency,reliable stability,and eco-friendly process.Flexible solid-state SCs as one of the ongoing focuses for the development of wearable and portable electronics have become the most promising energy storage devices for the smart power system due to their high power density,fast electrochemical response,high efficiency on the charge-discharge process,and excellent electrochemical stability.In this study,the recent progress in the electrodes and electrolytes used for approaching high-performance of the all-solid-state flexible SCs is reviewed.We first introduce basic operational principles of various SCs.And then we overview the electrode materials including carbon materials,conducting polymers,transition metal oxides/chalcogenides/nitrides,MXenes,metal-organic frameworks,covalent-organic frameworks,and the polymer-based solid-state electrolytes in different systems.Afterward,we summarize recent progress in the development of the all-solid-state flexible SCs and outlook for future research directions.展开更多
Carbon dioxide(CO_(2))geological utilization and storage(CGUS)is the key link of CO_(2)capture,utilization,and storage(CCUS).The accurate characterization of the geological body structure is a vital prerequisite of CG...Carbon dioxide(CO_(2))geological utilization and storage(CGUS)is the key link of CO_(2)capture,utilization,and storage(CCUS).The accurate characterization of the geological body structure is a vital prerequisite of CGUS.This paper gives a review of the multi-scale three-dimensional geological structure characterization and site selection of CO_(2)storage.It shows that there is a lack of systematic and high-precision methods for transparency characterization of multi-scale three-dimensional engineering geological structure and hydrogeological structure of a CO_(2)storage site.There is no clear understanding of the fracture evolution and gas-liquid migration process of multi-scale geological body structure under the disturbance of CO_(2)injection.There is a lack of sufficient quantitative methods for the dynamic evaluation of CO_(2)geological storage potential.The geological suitability evaluation method for site selection of CO_(2)storage is rough and has poor applicability,which is difficult to satisfy the urgent needs of CGUS site selection in the whole process of CO_(2)sequestration industrialization in the future.Thus,it is required to conduct studies on the transparency characterization of geological body structure and intelligent site selection for CO_(2)storage,which is of great importance for CGUS engineering practice.展开更多
基金We acknowledge the funding support from the National Natural Science Foundation of China Youth Fund(Grant No.52004019)the National Natural Science Foundation of China(Grant No.41825018)China Postdoctoral Science Foundation(Grant No.2023M733481).
文摘Rock-encased-backfill(RB)structures are common in underground mining,for example in the cut-andfill and stoping methods.To understand the effects of cyclic excavation and blasting activities on the damage of these RB structures,a series of triaxial stepwise-increasing-amplitude cyclic loading experiments was conducted with cylindrical RB specimens(rock on outside,backfill on inside)with different volume fractions of rock(VF=0.48,0.61,0.73,and 0.84),confining pressures(0,6,9,and 12 MPa),and cyclic loading rates(200,300,400,and 500 N/s).The damage evolution and meso-crack formation during the cyclic tests were analyzed with results from stress-strain hysteresis loops,acoustic emission events,and post-failure X-ray 3D fracture morphology.The results showed significant differences between cyclic and monotonic loadings of RB specimens,particularly with regard to the generation of shear microcracks,the development of stress memory and strain hardening,and the contact forces and associated friction that develops along the rock-backfill interface.One important finding is that as a function of the number of cycles,the elastic strain increases linearly and the dissipated energy increases exponentially.Also,compared with monotonic loading,the cyclic strain hardening characteristics are more sensitive to rising confining pressures during the initial compaction stage.Another finding is that compared with monotonic loading,more shear microcracks are generated during every reloading stage,but these microcracks tend to be dispersed and lessen the likelihood of large shear fracture formation.The transition from elastic to plastic behavior varies depending on the parameters of each test(confinement,volume fraction,and cyclic rate),and an interesting finding was that the transformation to plastic behavior is significantly lower under the conditions of 0.73 rock volume fraction,400 N/s cyclic loading rate,and 9 MPa confinement.All the findings have important practical implications on the ability of backfill to support underground excavations.
基金financial support from the National Natural Science Foundation of China(Nos.52174092,51904290,52004272,52104125,42372328,and U23B2091)Natural Science Foundation of Jiangsu Province,China(Nos.BK20220157 and BK20240209)+3 种基金the Fundamental Research Funds for the Central Universities,China(No.2022YCPY0202)Xuzhou Science and Technology Project,China(Nos.KC21033 and KC22005)Yunlong Lake Laboratory of Deep Underground Science and Engineering Project,China(No.104023002)the Graduate Innovation Program of China University of Mining and Technology(No.2023WLTCRCZL052)。
文摘This study aims to investigate mechanical properties and failure mechanisms of layered rock with rough joint surfaces under direct shear loading.Cubic layered samples with dimensions of 100 mm×100 mm×100 mm were casted using rock-like materials,with anisotropic angle(α)and joint roughness coefficient(JRC)ranging from 15°to 75°and 2-20,respectively.The direct shear tests were conducted under the application of initial normal stress(σ_(n)) ranging from 1-4 MPa.The test results indicate significant differences in mechanical properties,acoustic emission(AE)responses,maximum principal strain fields,and ultimate failure modes of layered samples under different test conditions.The peak stress increases with the increasingαand achieves a maximum value atα=60°or 75°.As σ_(n) increases,the peak stress shows an increasing trend,with correlation coefficients R² ranging from 0.918 to 0.995 for the linear least squares fitting.As JRC increases from 2-4 to 18-20,the cohesion increases by 86.32%whenα=15°,while the cohesion decreases by 27.93%whenα=75°.The differences in roughness characteristics of shear failure surface induced byαresult in anisotropic post-peak AE responses,which is characterized by active AE signals whenαis small and quiet AE signals for a largeα.For a given JRC=6-8 andσ_(n)=1 MPa,asαincreases,the accumulative AE counts increase by 224.31%(αincreased from 15°to 60°),and then decrease by 14.68%(αincreased from 60°to 75°).The shear failure surface is formed along the weak interlayer whenα=15°and penetrates the layered matrix whenα=60°.Whenα=15°,as σ_(n) increases,the adjacent weak interlayer induces a change in the direction of tensile cracks propagation,resulting in a stepped pattern of cracks distribution.The increase in JRC intensifies roughness characteristics of shear failure surface for a smallα,however,it is not pronounced for a largeα.The findings will contribute to a better understanding of the mechanical responses and failure mechanisms of the layered rocks subjected to shear loads.
基金support by the Science Fund of Shandong Laboratory of Advanced Materials and Green Manufacturing at Yantai(AMGM2021A03)the"Special Lubrication and Sealing for Aerospace"Shaanxi Provincial Science and Technology Innovation Team(2024RS-CXTD-63)+1 种基金the Xianyang2023 Key Research and Development Plan(L2023-ZDYF-QYCX-009)the World First Class University and First Class Academic Discipline Construction Funding 2023(0604024GH0201332,0604024SH0201332).
文摘Flexible and wearable pressure sensors hold immense promise for health monitoring,covering disease detection and postoperative rehabilitation.Developing pressure sensors with high sensitivity,wide detection range,and cost-effectiveness is paramount.By leveraging paper for its sustainability,biocompatibility,and inherent porous structure,herein,a solution-processed all-paper resistive pressure sensor is designed with outstanding performance.A ternary composite paste,comprising a compressible 3D carbon skeleton,conductive polymer poly(3,4-ethylene dioxythiophene):poly(styrenesulfonate),and cohesive carbon nanotubes,is blade-coated on paper and naturally dried to form the porous composite electrode with hierachical micro-and nano-structured surface.Combined with screen-printed Cu electrodes in submillimeter finger widths on rough paper,this creates a multiscale hierarchical contact interface between electrodes,significantly enhancing sensitivity(1014 kPa-1)and expanding the detection range(up to 300 kPa)of as-resulted all-paper pressure sensor with low detection limit and power consumption.Its versatility ranges from subtle wrist pulses,robust finger taps,to large-area spatial force detection,highlighting its intricate submillimetermicrometer-nanometer hierarchical interface and nanometer porosity in the composite electrode.Ultimately,this all-paper resistive pressure sensor,with its superior sensing capabilities,large-scale fabrication potential,and cost-effectiveness,paves the way for next-generation wearable electronics,ushering in an era of advanced,sustainable technological solutions.
基金supported by the National Natural Science Foundation of China (Grant Nos. 12374012, 11974208, 52172212, and 52002217)Shandong Provincial Natural Science Foundation (Grant Nos. ZR2023JQ001, ZR2020YQ05, and 2019KJJ020)financial support from the Program of Distinguished Expert of Taishan Scholar (Grant No. tstp20221124)。
文摘As a sister compound of PbTe, SnTe possesses the environmentally friendly elements. However, the pristine SnTe compounds suffer from the high carrier concentration, the large valence band offset between the L and Σpositions and high thermal conductivity. Using high-pressure and high-temperature technology, we synthesized the pristine SnTe samples at different pressures and systemically investigated their thermoelectric properties.High pressure induces rich microstructures, including the high-density dislocations and lattice distortions, which serve as the strong phonon scattering centers, thereby reducing the lattice thermal conductivity. For the electrical properties, pressure reduces the harmful high carrier concentration, due to the depression of Sn vacancies.Moreover, pressure induces the valence band convergence, reducing the energy separation between the L and Σpositions. The band convergence and suppressed carrier concentration increase the Seebeck coefficient. Thus, the power factors of pressure-sintered compounds do not deteriorate significantly under the condition of decreasing electrical conductivity. Ultimately, for a pristine SnTe compound synthesized at 5 GPa, a higher ZT value of 0.51 is achieved at 750 K, representing a 140% improvement compared to the value of 0.21 obtained using SPS. Therefore, the high-pressure and high-temperature technology is demonstrated as an effectively approach to optimize thermoelectric performance.
基金This work used the Extreme Science and Engineering Discovery Environment(XSEDE)Bridges system,which is supported by National Science Foundation Grant Number ACI-1548562.
文摘Defects in graphene can profoundly impact its extraordinary properties,ultimately influencing the performances of graphene-based nanodevices.Methods to detect defects with atomic resolution in graphene can be technically demanding and involve complex sample preparations.An alternative approach is to observe the thermal vibration properties of the graphene sheet,which reflects defect information but in an implicit fashion.Machine learning,an emerging data-driven approach that offers solutions to learning hidden patterns from complex data,has been extensively applied in material design and discovery problems.In this paper,we propose a machine learning-based approach to detect graphene defects by discovering the hidden correlation between defect locations and thermal vibration features.Two prediction strategies are developed:an atom-based method which constructs data by atom indices,and a domain-based method which constructs data by domain discretization.Results show that while the atom-based method is capable of detecting a single-atom vacancy,the domain-based method can detect an unknown number of multiple vacancies up to atomic precision.Both methods can achieve approximately a 90%prediction accuracy on the reserved data for testing,indicating a promising extrapolation into unseen future graphene configurations.The proposed strategy offers promising solutions for the non-destructive evaluation of nanomaterials and accelerates new material discoveries.
基金National Natural Science Foundation of China (No. 11575184).
文摘A novel real time fast electron bremsstrahlung (FEB) diagnostic system based on the lutetium yttrium oxyorthosilicate scintillators (LYSO) and silicon photomultipliers (SiPM) has been developed for tokamak.The diagnostic system is dedicated to study the FEB emission in the hard x-ray (HXR) energy range between 10 and 200 keV during the lower hybrid current drive.The system consists of a detection module and three data acquisition and processing (DAP)boards.The detection module consists of annulus LYSO-SiPM detector array and a 12-channel preamplifier module.The DAP boards upload the data to the host computer for displaying and storing through PXI bus.The time and space resolutions of the system are 10 ms and 4 cm,respectively.The experimental results can show the evolution over time and the spatial distribution of FEB.This paper presents the system performance and typical discharge results.
基金supported by the National Natural Science Foundation of China(Grant No.41825018)the Second Tibetan Plateau Scientific Expedition and Research Program(STEP)(Grant No.2019QZKK0904).
文摘Discontinuities are often considered as important factors responsible for the instability caused by shear failure in engineering rock mass,and energy-driven instability is the root cause of rock failure.However,few studies focus on the energy evolution during the failure process using a three-dimensional(3D)numerical model.In this study,a series of laboratory direct shear tests on rock-like samples is numer-ically simulated using bonded particle models(BPMs)with multiple combinations of discontinuous in the particle flow code(PFC3D),in which the location and size of the particles conform to the uniform distribution.The effects of joint row number and inclination on the stress-strain characteristics and failure mode of rock were studied from the perspective of microcrack growth and energy evolution.The results showed that,when the number of joint rows Nr>1,the shear failure region does not change with the increase of Nr for the type B(2-columnn multiple-row at center)and the type C(2-column multiple-row at edge)as compared to the type A(1-column multiple-row at center)joint models.Notably,joints significantly increase the post-peak energy dissipation but have little effect on the proportion of energy before the peak.Friction consumes most of the energy while kinetic energy accounts for less than 1%of total energy during the shear process.Peak elastic strain energy follows the variation trend of peak shear displacement.The development and accumulation of microcracks directly affect the energy dissipation,and there is a significant linear relationship between the cumulative number of critical microcracks and the critical dissipated energy at the failure,when the dip direction of joints is opposite to the shear direction,more microcracks will be accumulated at the peak time,resulting in more energy dissipation.The results contribute to deeply understanding the shear failure process of non-persistent jointed mass.
基金Reform and Development Special Project in 2020-Project of Engineering Research Center of Tibetan Medicine Detection Technology,Ministry of Education(324042000101)Major Project Cultivation Program of Xizang Minzu University(22MDZ02)Key Project of Tibet Natural Science Foundation(XZ202001ZR0087G)。
文摘Vicatia thibetica de Boiss is a Tibetan medicinal herb and mainly contains chemical components such as flavonoids,β-sitosterol and ferulic acid.It has good pharmacological effects such as anti-inflammatory,analgesic,anti-fatigue,anti-oxidation,anti-aging and enhancing immunity.Based on relevant domestic and foreign literature,this paper comprehensively reviews the main components,pharmacological activity and clinical prescription application of V.thibetica de Boiss,to provide a reference for the in-depth research and comprehensive development and utilization of V.thibetica de Boiss.
基金supported by the Trade Union of the University of Science and Technology of Chinathe National Natural Science Foundation of China (71801205, 72171217)+1 种基金the Fundamental Research Funds for the Central Universities (WK2040000031)the BNU-HKBU United International C ollege Research Start-Up Fund (R72021123)
基金supported by National Natural Science Foundation of China (No. 1157518)
文摘A digital pulse analysis system is an important diagnostic system in nuclear physics experimental research.In response to the demand for reflecting the particle state in a nuclear physics experiment,we have designed and developed a real-time digital pulse analysis system and applied it to the digital nuclear pulse waveform discrimination of different detectors in the HL-2M tokamak.The system is based on the peripheral component interconnect extensions for instrumentation(PXI)platform,while its software was written in LABVIEW.The key technologies involved in the system implementation include digital pulse analysis technology,digital discrimination technology,pulse height analysis technology,etc.The system has been applied to the plastic scintillator detector at the Neutron Source Lab of the University of Science and Technology of China.And the experimental results indicate that the system can discriminate between neutron(n)particles and gamma(γ)particles well when used to measure the plastic scintillator detector.
文摘We propose the Forward-Backward Synergistic Acceleration Pursuit (FBSAP) algorithm in this paper. The FBSAP algorithm inherits the advantages of the Forward-Backward Pursuit (FBP) algorithm, which has high success rate of reconstruction and does not necessitate the sparsity level as a priori condition. Moreover, it solves the problem of FBP that the atom can be selected only by the fixed step size. By mining the correlation between candidate atoms and residuals, we innovatively propose the forward acceleration strategy to adjust the forward step size adaptively and reduce the computation. Meanwhile, we accelerate the algorithm further in backward step by fusing the strategy proposed in Acceleration Forward-Backward Pursuit (AFBP) algorithm. The experimental simulation results demonstrate that FBSAP can greatly reduce the running time of the algorithm while guaranteeing the success rate in contrast to FBP and AFBP.
基金financially supported by the National Natural Science Foundation of China(81971632,51773231)the Natural Science Foundation of Guangdong Province(2020A1515010425,2022A1515010024)+1 种基金Key Scientific and Technological Program of Guangzhou City(201802020023)Shenzhen Science and Technology Project(JCYJ20190807160801664,JCYJ20220818103207016).
文摘Image-guided thermal ablation(TA),which is less invasive,has been widely applied for treating various kinds of tumors.However,TA still poses the potential risk of thermal damage to sensitive tissue nearby.Therefore,an adjunctive thermoprotective hydrodissection technique with constant injection of 5%glucose(5%Glu)has currently been adopted for clinical application,but this may be hazardous to humans.In this study,a multifunctional hyaluronic acid-based hydrogel(HA-Dc)was developed for hydrodissection.Compared with 5%Glu(the most clinically used solution)and the previously reported F127 hydrogel,the HA-Dc hydrogel was studied in vitro in a porcine liver model and in vivo in a rabbit model and showed good injectability and better tissue retention,stability,and thermoprotective properties throughout the TA procedure.Furthermore,in the preclinical evaluation in a Macaca fascicularis(M.fascicularis)model,HA-Dc showed excellent performance in terms of stricter neuroprotection compared with 5%Glu.In addition,the HA-Dc hydrogel with good biocompatibility and controllable degradation behavior in vivo could be a promising platform for thermal protection during clinical TA procedures.
基金supported by grants from the National Key Research and Development Program of China(2020YFA0907300)the National Natural Science Foundation of China(Nos.U2006219 and 51871050)+2 种基金the Fundamental Research Funds for the Central Universities(Nos.N180203019 and N2002019)Liaoning Revitalization Talents Program(No.XLYC1907158)Basic Scientific Research Project of Education Department of Liaoning Province and Shenyang Young and middle-aged Scientific and Technological Innovation Talents Support Program(RC210001).
文摘316L stainless steel(SS)is widely applied as microimplant anchorage(MIA)due to its excellent mechanical properties.However,the risk that the oral microorganisms can corrode 316L SS is fully neglected.Microbiologically influenced corrosion(MIC)of 316L SS is essential to the health and safety of all patients because the accelerated corrosion caused by the oral microbiota can trigger the release of Cr and Ni ions.This study investigated the corrosion behavior and mechanism of subgingival microbiota on 316L SS by 16S rRNA and metagenome sequencing,electrochemical measurements,and surface characterization techniques.Multispecies biofilms were formed by the oral subgingival microbiota in the simulated oral anaerobic environment on 316L SS surfaces,significantly accelerating the corrosion in the form of pitting.The microbiota samples collected from the subjects differed in biofilm compositions,corrosion behaviors,and mechanisms.The oral subgingival microbiota contributed to the accelerated corrosion of 316L SS via acidic metabolites and extracellular electron transfer.Our findings provide a new insight into the underlying mechanisms of oral microbial corrosion and guide the design of oral microbial corrosion-resistant materials.
基金supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA23090402)the National Natural Science Foundation of China(Nos.41790442,41825018)the Second Tibetan Plateau Scientific Expedition and Research Program(STEP)(No.2019QZKK0904)。
文摘The influence of different types of roots on the soil is complex and still remains unclear.Four in-situ extrusion tests were conducted on two types of root systems,namely fibrous and tap root system,for three plants,Eleusine indica,Potentilla anserine,and Artemisia argyi,according to the classification in Botany,and the thrust-displacement curves and failure patterns of different samples were analysed by comparison to fill the aforementioned gap.Results reveal that the roots can reduce the characteristics of soil brittleness and enhance its capability to resist large deformation,and different root types contribute different effects to the strain-hardening behavior of the root-soil mass.The contribution of the fibrous root system to strength is limited,whilst the tap root system substantially enhances strength and stiffness.Results of failure patterns show that fibrous and tap root systems affect soil solidification and surface cracking reduction.However,the effect of the tap root system depends on the composition of lateral and tap roots:long and rich lateral roots are effective for resisting the creation of cracks,but thick tap roots with few and thin lateral roots may lead to several surface cracks.
基金supported by the National Natural Science Foundation of China(No.51875365)the Liaoning Province Science and Technology Plan Joint Fund Project(Nos.2023-BSBA-248 and 2023-MSLH-265)the Scientific Research Fund of Liaoning Provincial Education Department(No.LJKZ0122).
文摘In this work,the Al-Cu-Mg alloy with different Y(0-0.2 wt%)and Ce(0.5-1.5 wt%)are designed.The effect of mixed addition of Y and Ce on the grain structure and hot tearing for Al-4.4Cu-1.5Mg-0.15Zr alloy was investigated using"cross"hot tearing mould.The results indicate that as rare earth Y and Ce increases,the grain size becomes finer,the grain morphology changes from dendrite to equiaxed grain,and effectively reduce the hot tearing sensitivity coefficient(HTS1)and crack susceptibility coefficient(CSC)of the alloy.With the increase of Ce element(0.5-1.5 wt%),the hot tearing susceptibility of the alloy decreases first and then increases.With the increase of Y element(0-0.2 wt%),the hot tearing sensitivity of the alloy decreases.When the content of rare earth is 0.2 wt%Y+1.0 wt%Ce,the minimum HTS1 value and CSC value of the alloy are 68 and 0.53,respectively.Rare earth Ce refines the alloy microstructure,shortens the feeding channel,and reduces the hot tearing initiation.Meanwhile,the rare earth Y can form Al6Cu6Y phase at the grain boundary,improve the feeding capacity of the alloy.Therefore,appropriate addition of rare earth Y and Ce can effectively reduce the hot tearing tendency of the alloy.
基金supported by the National Natural Science Foundation of China(Grant No.:82074104)the Research Project of Clinical Toxicology Transformation from the Chinese Society of Toxicology,China(Grant No.:CST2021CT101)the Chinese Academy of Medical Science Innovation Fund for Medical Sciences,China(Grant Nos.:2017-I2M-1-011 and 2022-I2M-2-002).
文摘Pulmonary fibrosis (PF) is a chronic progressive end-stage lung disease. However, the mechanisms underlying the progression of this disease remain elusive. Presently, clinically employed drugs are scarce for the treatment of PF. Hence, there is an urgent need for developing novel drugs to address such diseases. Our study found for the first time that a natural source of Prismatomeris connata Y. Z. Ruan (Huang Gen, HG) ethyl acetate extract (HG-2) had a significant anti-PF effect by inhibiting the expression of the transforming growth factor beta 1/suppressor of mothers against decapentaplegic (TGF-β1/Smad) pathway. Network pharmacological analysis suggested that HG-2 had effects on tyrosine kinase phosphorylation, cellular response to reactive oxygen species, and extracellular matrix (ECM) disassembly. Moreover, mass spectrometry imaging (MSI) was used to visualize the heterogeneous distribution of endogenous metabolites in lung tissue and reveal the anti-PF metabolic mechanism of HG-2, which was related to arginine biosynthesis and alanine, asparate and glutamate metabolism, the downregulation of arachidonic acid metabolism, and the upregulation of glycerophospholipid metabolism. In conclusion, we elaborated on the relationship between metabolite distribution and the progression of PF, constructed the regulatory metabolic network of HG-2, and discovered the multi-target therapeutic effect of HG-2, which might be conducive to the development of new drugs for PF.
基金supported by Technological Innovation(“Climbing Program”Special Funds,pdjh2024c11603).
文摘In modern Wi-Fi systems,channel state information(CSI)serves as a foundational support for various sensing applications.Currently,existing CSI-based techniques exhibit limitations in terms of environmental adaptability.As such,optimizing the utilization of subcarrier CSI stands as a critical avenue for enhancing sensing performance.Within the OFDM communication framework,this work derives sensing outcomes for both detection and estimation by harnessing the CSI from every individual measured subcarrier,subsequently consolidating these outcomes.When contrasted against results derived from CSI based on specific extraction protocols or those obtained through weighted summation,the methodology introduced in this study offers substantial improvements in CSI-based detection and estimation performance.This approach not only underscores the significance but also serves as a robust exemplar for the comprehensive application of CSI.
基金financial supports from the Fundamental Research Funds for the Central Universities, China (No. HIT. NSRIF. 2020014)the National Natural Science Foundation of China (No. 12102103)
文摘Due to wear and manufacturing tolerance,the freeplay is unavoidable in the hinges of folding fins,which exerts significant effects on the aerodynamic characteristics.This paper proposes a backbone-curve-based framework for the dynamical identification of folding fins containing the freeplay nonlinearity.With no need to measure the input force signal and the response signals of nonlinear related Degrees of Freedom(DOFs),the proposed method is more direct and elegant than most existing nonlinear identification approaches,and it contains three steps:Firstly,the underlying linear model of the folding fin structure is obtained through the modal test on its linear sub-parts,and then,the harmonic approximation solves the analytical expressions of the backbone curves of measurable DOFs.Secondly,response data measured from the sine-sweep test are used to extract the fitting points of backbone curves for these DOFs.Finally,the curve fitting approach is applied to identify the freeplay parameters.A series of numerical experiments verify the effectiveness of the proposed method.A real-life folding fin structure is also employed to illustrate how the method can be applied.These examples demonstrate that the identification framework can give an accurate dynamic model of the folding fin structure.
文摘In the past few years,supercapacitors(SCs)have attracted great attention in both academic and industrial sectors due to their high energy storage efficiency,reliable stability,and eco-friendly process.Flexible solid-state SCs as one of the ongoing focuses for the development of wearable and portable electronics have become the most promising energy storage devices for the smart power system due to their high power density,fast electrochemical response,high efficiency on the charge-discharge process,and excellent electrochemical stability.In this study,the recent progress in the electrodes and electrolytes used for approaching high-performance of the all-solid-state flexible SCs is reviewed.We first introduce basic operational principles of various SCs.And then we overview the electrode materials including carbon materials,conducting polymers,transition metal oxides/chalcogenides/nitrides,MXenes,metal-organic frameworks,covalent-organic frameworks,and the polymer-based solid-state electrolytes in different systems.Afterward,we summarize recent progress in the development of the all-solid-state flexible SCs and outlook for future research directions.
基金supported by the National Natural Science Foundation of China(Grant No.42141009)the Key Research Program of the Institute of Geology and Geophysics,CAS(Grant No.IGGCAS-202201).
文摘Carbon dioxide(CO_(2))geological utilization and storage(CGUS)is the key link of CO_(2)capture,utilization,and storage(CCUS).The accurate characterization of the geological body structure is a vital prerequisite of CGUS.This paper gives a review of the multi-scale three-dimensional geological structure characterization and site selection of CO_(2)storage.It shows that there is a lack of systematic and high-precision methods for transparency characterization of multi-scale three-dimensional engineering geological structure and hydrogeological structure of a CO_(2)storage site.There is no clear understanding of the fracture evolution and gas-liquid migration process of multi-scale geological body structure under the disturbance of CO_(2)injection.There is a lack of sufficient quantitative methods for the dynamic evaluation of CO_(2)geological storage potential.The geological suitability evaluation method for site selection of CO_(2)storage is rough and has poor applicability,which is difficult to satisfy the urgent needs of CGUS site selection in the whole process of CO_(2)sequestration industrialization in the future.Thus,it is required to conduct studies on the transparency characterization of geological body structure and intelligent site selection for CO_(2)storage,which is of great importance for CGUS engineering practice.