目的:调查和了解军队医院开展治疗药物监测(therapeutic drug monitoring,TDM)的情况。方法:利用互联网技术,借助移动网络平台设计、传送、提交、回收问卷并进行统计分析。结果:回收有效问卷40份,涉及总医院14份、军医大学附属医院7份...目的:调查和了解军队医院开展治疗药物监测(therapeutic drug monitoring,TDM)的情况。方法:利用互联网技术,借助移动网络平台设计、传送、提交、回收问卷并进行统计分析。结果:回收有效问卷40份,涉及总医院14份、军医大学附属医院7份、中心医院19份,分布于中国大陆21个省、直辖市、自治区。80%的军队医院开展了药物浓度检测,以免疫抑制剂、抗感染药物、抗癫药物等为主。单品种检测量较多的是他克莫司、吗替麦考酚酸、雷帕霉素、环孢素、丙戊酸钠和万古霉素。60%的军队医院开展了药物基因检测,检测量较多的是CYP2C19、CYP2C9、VKORC1、CYP3A5、CYP2D6、HLA-B*1502、MTHFR及UGT等相关基因。22.5%的军队医院开展了药物代谢检测,其中一半以上于2010年以后才开展。结论:本次问卷调查客观反映了当前军队医院TDM工作的开展现状,为今后更好地开展TDM工作、明确学科发展方向以及制定政策规范提供了有意义的参考依据。展开更多
引入基于Outcome Based Education(OBE)教育理念,贯彻形成性评价思想,注重学生学习过程,重视评价反馈机制,从教学目标制定和问卷设计、学生自评、课程团队讨论与改进,以及学习成效评测四个方面阐述材料加工冶金传输原理课程改革。实现...引入基于Outcome Based Education(OBE)教育理念,贯彻形成性评价思想,注重学生学习过程,重视评价反馈机制,从教学目标制定和问卷设计、学生自评、课程团队讨论与改进,以及学习成效评测四个方面阐述材料加工冶金传输原理课程改革。实现课程科学评价与持续改进机制,不断提升人才培养质量,逐步完善高质量材料成型及控制工程专业课程建设。展开更多
The thermal scratch seriously affects the surface quality of the cold rolled stainless steel strip. Some researchers have carried out qualitative and theoretical studies in this field. However, there is currently a la...The thermal scratch seriously affects the surface quality of the cold rolled stainless steel strip. Some researchers have carried out qualitative and theoretical studies in this field. However, there is currently a lack of research on effective forecast and control of thermal scratch defects in practical production, especially in tandem cold rolling. In order to establish precise mathematical model of oil film thickness in deformation zone, the lubrication in cold rolling process of SUS410L stainless steel strip is studied, and major factors affecting oil film thickness are also analyzed. According to the principle of statistics, mathematical model of critical oil film thickness in deformation zone for thermal scratch is built, with fitting and regression analytical method, and then based on temperature comparison method, the criterion for deciding thermal scratch defects is put forward. Storing and calling data through SQL Server 2010, a software on thermal scratch defects control is developed through Microsoft Visual Studio 2008 by MFC technique for stainless steel in tandem cold rolling, and then it is put into practical production. Statistics indicate that the hit rate of thermal scratch is as high as 92.38%, and the occurrence rate of thermal scratch is decreased by 89.13%. Owing to the application of the software, the rolling speed is increased by approximately 9.3%. The software developed provides an effective solution to the problem of thermal scratch defects in tandem cold rolling, and helps to promote products surface quality of stainless steel strips in practical production.展开更多
文摘目的:调查和了解军队医院开展治疗药物监测(therapeutic drug monitoring,TDM)的情况。方法:利用互联网技术,借助移动网络平台设计、传送、提交、回收问卷并进行统计分析。结果:回收有效问卷40份,涉及总医院14份、军医大学附属医院7份、中心医院19份,分布于中国大陆21个省、直辖市、自治区。80%的军队医院开展了药物浓度检测,以免疫抑制剂、抗感染药物、抗癫药物等为主。单品种检测量较多的是他克莫司、吗替麦考酚酸、雷帕霉素、环孢素、丙戊酸钠和万古霉素。60%的军队医院开展了药物基因检测,检测量较多的是CYP2C19、CYP2C9、VKORC1、CYP3A5、CYP2D6、HLA-B*1502、MTHFR及UGT等相关基因。22.5%的军队医院开展了药物代谢检测,其中一半以上于2010年以后才开展。结论:本次问卷调查客观反映了当前军队医院TDM工作的开展现状,为今后更好地开展TDM工作、明确学科发展方向以及制定政策规范提供了有意义的参考依据。
文摘引入基于Outcome Based Education(OBE)教育理念,贯彻形成性评价思想,注重学生学习过程,重视评价反馈机制,从教学目标制定和问卷设计、学生自评、课程团队讨论与改进,以及学习成效评测四个方面阐述材料加工冶金传输原理课程改革。实现课程科学评价与持续改进机制,不断提升人才培养质量,逐步完善高质量材料成型及控制工程专业课程建设。
基金Supported by National Natural Science Foundation of China(Grant Nos.51174057,51274062)National High Technology Research and Development Program of China(863 Program,Grant No.2012AA03A503)
文摘The thermal scratch seriously affects the surface quality of the cold rolled stainless steel strip. Some researchers have carried out qualitative and theoretical studies in this field. However, there is currently a lack of research on effective forecast and control of thermal scratch defects in practical production, especially in tandem cold rolling. In order to establish precise mathematical model of oil film thickness in deformation zone, the lubrication in cold rolling process of SUS410L stainless steel strip is studied, and major factors affecting oil film thickness are also analyzed. According to the principle of statistics, mathematical model of critical oil film thickness in deformation zone for thermal scratch is built, with fitting and regression analytical method, and then based on temperature comparison method, the criterion for deciding thermal scratch defects is put forward. Storing and calling data through SQL Server 2010, a software on thermal scratch defects control is developed through Microsoft Visual Studio 2008 by MFC technique for stainless steel in tandem cold rolling, and then it is put into practical production. Statistics indicate that the hit rate of thermal scratch is as high as 92.38%, and the occurrence rate of thermal scratch is decreased by 89.13%. Owing to the application of the software, the rolling speed is increased by approximately 9.3%. The software developed provides an effective solution to the problem of thermal scratch defects in tandem cold rolling, and helps to promote products surface quality of stainless steel strips in practical production.
