Background: The diversified and high value-added utilization of cotton by products can promote the sustainable development of modern agriculture. Di erences in potential nutrients among varieties can be explained by v...Background: The diversified and high value-added utilization of cotton by products can promote the sustainable development of modern agriculture. Di erences in potential nutrients among varieties can be explained by variations in the composition and abundance of fatty acids, polyphenols, carbohydrates, amino acids, and organic acids. Therefore, the analysis of metabolite species and relationships in cottonseed is meaningful for the development of cotton byproducts.Results: In this study, the metabolomes of three representative cotton cultivars of di erent species were compared using untargeted GC-TOF/MS analysis. A total of 263 metabolites were identified from 705 peaks, and their levels were compared across cultivars. Principal component analysis and OPLS-DA clearly distinguish these samples based on metabolites. There were significant di erences in the contents of amino acids, carbohydrates, organic acids, flavonoids, and lipids in G. hirsutum TM-1 compared with G. arboreum Shixiya1 and G. barbadense Hai7124. Notably, the bioactive nutrient compound catechin obtained from the di erential metabolites significantly accumulated in TM-1. Furthermore, a comprehensive analysis using catechin and oil-related traits was conducted in core collections of Gossypium hirsutum. The results revealed the reliability of the GC-TOF/MS analysis, as well as that catechin content has a negative association with myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, arachidic acid, and total fatty acids.Conclusion: These findings suggest that untargeted GC-TOF/MS analysis could provide a new method for investigating the underlying plant biochemistry of nutrient variation in cottonseed, and that catechin content has a negative association with oil-related traits in cottonseed. This study may pave the way to exploit the value of cotton byproducts.展开更多
目的全面分析国内外对维持性血液透析患者疲乏领域的研究现况、热点以及发展趋势,以便为未来研究方向提供参考依据。方法通过中国知网、维普、万方、Web of ScienceTM核心合集数据库检索从建库至2022年12月30日前发表的维持性血液透析...目的全面分析国内外对维持性血液透析患者疲乏领域的研究现况、热点以及发展趋势,以便为未来研究方向提供参考依据。方法通过中国知网、维普、万方、Web of ScienceTM核心合集数据库检索从建库至2022年12月30日前发表的维持性血液透析患者疲乏状态的相关文献,利用CiteSpace 6.1.R3对其进行可视化分析。结果共纳入中文文献152篇、英文文献110篇,国外最早于1996年发文,国内最早发文在2011年且发文量从2017年开始呈大幅度上升趋势。研究重点国内外主要集中在透析患者疲乏的影响因素及干预措施上,国外研究者对"抑郁"情绪相关性研究、有氧运动正向干预关注较多,此外我国对中医理疗芳香疗法缓解患者疲乏也正在积极探索。结论未来临床工作者应注重维持性血液透析患者疲劳评估,并用大规模纵向研究探讨疲乏的影响因素,以便更好地为治疗疲乏提供干预靶目标;同时进行高质量前瞻性干预研究,以期把该类患者疲乏状态改善最大化,形成规范指南推广应用。展开更多
基金supported by China Agriculture Research System(CARS-15-27)Agricultural Science and Technology Innovation Program of Chinese Academy of Agricultural Sciences.
文摘Background: The diversified and high value-added utilization of cotton by products can promote the sustainable development of modern agriculture. Di erences in potential nutrients among varieties can be explained by variations in the composition and abundance of fatty acids, polyphenols, carbohydrates, amino acids, and organic acids. Therefore, the analysis of metabolite species and relationships in cottonseed is meaningful for the development of cotton byproducts.Results: In this study, the metabolomes of three representative cotton cultivars of di erent species were compared using untargeted GC-TOF/MS analysis. A total of 263 metabolites were identified from 705 peaks, and their levels were compared across cultivars. Principal component analysis and OPLS-DA clearly distinguish these samples based on metabolites. There were significant di erences in the contents of amino acids, carbohydrates, organic acids, flavonoids, and lipids in G. hirsutum TM-1 compared with G. arboreum Shixiya1 and G. barbadense Hai7124. Notably, the bioactive nutrient compound catechin obtained from the di erential metabolites significantly accumulated in TM-1. Furthermore, a comprehensive analysis using catechin and oil-related traits was conducted in core collections of Gossypium hirsutum. The results revealed the reliability of the GC-TOF/MS analysis, as well as that catechin content has a negative association with myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, arachidic acid, and total fatty acids.Conclusion: These findings suggest that untargeted GC-TOF/MS analysis could provide a new method for investigating the underlying plant biochemistry of nutrient variation in cottonseed, and that catechin content has a negative association with oil-related traits in cottonseed. This study may pave the way to exploit the value of cotton byproducts.
文摘目的全面分析国内外对维持性血液透析患者疲乏领域的研究现况、热点以及发展趋势,以便为未来研究方向提供参考依据。方法通过中国知网、维普、万方、Web of ScienceTM核心合集数据库检索从建库至2022年12月30日前发表的维持性血液透析患者疲乏状态的相关文献,利用CiteSpace 6.1.R3对其进行可视化分析。结果共纳入中文文献152篇、英文文献110篇,国外最早于1996年发文,国内最早发文在2011年且发文量从2017年开始呈大幅度上升趋势。研究重点国内外主要集中在透析患者疲乏的影响因素及干预措施上,国外研究者对"抑郁"情绪相关性研究、有氧运动正向干预关注较多,此外我国对中医理疗芳香疗法缓解患者疲乏也正在积极探索。结论未来临床工作者应注重维持性血液透析患者疲劳评估,并用大规模纵向研究探讨疲乏的影响因素,以便更好地为治疗疲乏提供干预靶目标;同时进行高质量前瞻性干预研究,以期把该类患者疲乏状态改善最大化,形成规范指南推广应用。