Global trends in publications regarding macrophages-related diabetic foot ulcers in the last two decades

BACKGROUND Diabetic foot ulcers(DFUs)are one of the most severe and popular complications of diabetes.The persistent non-healing of DFUs is the leading cause of amputation,which causes significant mental and financial stress to patients and their families.Macrophages are critical cells in wound healing and perform essential roles in all phases of wound healing.However,no studies have been carried out to systematically illustrate this area from a scientometric point of view.Although there have been some bibliometric studies on diabetes,reports focusing on the investigation of macrophages in DFUs are lacking.AIM To perform a bibliometric analysis to systematically assess the current state of research on macrophage-related DFUs.METHODS The publications of macrophage-related DFUs from January 1,2004,to December 31,2023,were retrieved from the Web of Science Core Collection on January 9,2024.Four different analytical tools:VOSviewer(v1.6.19),CiteSpace(v6.2.R4),HistCite(v12.03.07),and Excel 2021 were used for the scientometric research.RESULTS A total of 330 articles on macrophage-related DFUs were retrieved.The most published countries,institutions,journals,and authors in this field were China,Shanghai Jiao Tong University of China,Wound Repair and Regeneration,and Aristidis Veves.Through the analysis of keyword co-occurrence networks,historical direct citation networks,thematic maps,and trend topics maps,we synthesized the prevailing research hotspots and emerging trends in this field.CONCLUSION Our bibliometric analysis provides a comprehensive overview of macrophage-related DFUs research and insights into promising upcoming research.

Rushan earthquake swarm in eastern China and its indications of fluid-triggered rupture

An extraordinary earthquake swarm occurred at Rushan on the Jiaodong Peninsula from October 1, 2013, onwards, and more than 12,000 aftershocks had been detected by December 31, 2015. All the activities of the whole swarm were recorded at the nearest station, RSH, which is located about 12 km from the epicenter. We examine the statistical characteristics of the Rushan swarm in this paper using RSH station data to assess the arrival time difference, ts p, of Pg and Sg phases. A temporary network comprising 18 seismometers was set up on May 6, 2014, within the area of the epicenter; based on the data from this network and use of the double difference method, we determine precise hypocenter locations. As the distribution of relocated sources reveals migration of seismic activity, we applied the mean-shift cluster method to perform clustering analysis on relocated catalogs. The results of this study show that there were at least 16 clusters of seismic activities between May 6, 2014, and June 30, 2014, and that each was characterized by a hypocenter spreading process. We estimated the hydraulic diffusivity, D, of each cluster using envelope curve fitting; the results show that D values range between 1.2 and 3.5 m2/d and that approximate values for clusters on the edge of the source area are lower than those within the central area. We utilize an epidemic-type aftershock sequence （ETAS） model to separate external triggered events from self-excited aftershocks within the Rushan swarm. The estimated parameters for this model suggest that α = 1.156, equiva- lent to sequences induced by fluid-injection, and that the forcing rate （μ） implies just 0.15 events per day. These estimates indicate that around 3% of the events within the swarm were externally triggered. The fact that variation in μ is synchronous with swarm activity implies that pulses in fluid pressure likely drove this series of earthquakes.

Waveform inversion and analysis of an unusual earthquake swarm in the Boshan mining area, Shandong Province, China

Moment tensor solutions were retrieved for the earthquake swarm that occurred during November and December 2010 in the Boshan mining area, Shandong Province, China. The results showed that the double-couple components in the source mechanisms were higher at the beginning of the swarm and consisted mainly of shear faulting controlled by tectonic stress. The subsequent events had significant non-double-couple components, indicating tensile faulting. The double-couple components predominately presented as normal faulting and the P axes were orientated almost vertically. The slip vectors of the swarm events were relatively stable. With reference to the tectonic features near the epicenter, we concluded that the swarm was a result of subordinate fault motion related to the Wangmu Mountain fault and that high-pressure pore fluids played a crucial role in the activity of the earthquake swarm.