Objective\ In order to study the relationship between alcohol abuse and oxidative stress, and to identify oxidative damage of alcohol abuse in human bodies. Methods\ 80 cases of male alcoholics (AL) aged 40 years ol...Objective\ In order to study the relationship between alcohol abuse and oxidative stress, and to identify oxidative damage of alcohol abuse in human bodies. Methods\ 80 cases of male alcoholics (AL) aged 40 years old and 80 cases of male healthy volunteers (HV) of the same age without drinking history were investigated by measuring concentrations of vitamin C (VC), vitamin E (VE) and β-carotene (β-CAR) in plasma as well as activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) in RBC with spectrophotometric assays. Results\ Compared with the average values (AV) of the above biochemical parameters in the HV group, the average values of VC, VE and β-CAR in plasma and the activities of SOD, CAT and GSH-Px in RBC in the AL group were significantly decreased (P = 0.0000). The findings in linear regression and correlation analysis for 80 alcoholics showed that with the prolonged drinking duration and increased daily drinking quantity, the values of VC, VE and β-CAR in plasma as well as SOD, CAT and GSH-Px in RBC in the alcoholics were gradually decreased (P = 0.000), representing a respectively significant linear negative correlation. The analysis of stepwise regression and correlation revealed that the drinking duration had the closest correlation with the values of VE in plasma as well as CAT and GSH-Px in RBC, while the daily drinking quantity had the closest correlation with the values of VC, VE and β-CAR in plasma as well as SOD and GSH-Px in RBC. Conclusion\ The findings of the present study suggested that the oxidative stress in the alcoholics became pathologically intensified, leading to potential oxidative damages in their bodies. Therefore, alcoholics should abstain from alcohol drinking, and should take as supplements suitable dosage of antioxidants per day such as VC, VE, β-CAR and others to moderate potential oxidative damages in their bodies.展开更多
A methodology is proposed to handle problem that under equiproble address of packet traffic at the input port, Generalized Shuffle-Exchange Network (GSEN) routes traffic unevenly because of the unbalanced routing tags...A methodology is proposed to handle problem that under equiproble address of packet traffic at the input port, Generalized Shuffle-Exchange Network (GSEN) routes traffic unevenly because of the unbalanced routing tags. The idea is to use routing tag according to probability, which can be evaluated by using Moore-Penrose inverse in matrix analysis. An instance is used to illustrate the idea, and the simulation is done to show the improvement in performance issues.展开更多
文摘Objective\ In order to study the relationship between alcohol abuse and oxidative stress, and to identify oxidative damage of alcohol abuse in human bodies. Methods\ 80 cases of male alcoholics (AL) aged 40 years old and 80 cases of male healthy volunteers (HV) of the same age without drinking history were investigated by measuring concentrations of vitamin C (VC), vitamin E (VE) and β-carotene (β-CAR) in plasma as well as activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) in RBC with spectrophotometric assays. Results\ Compared with the average values (AV) of the above biochemical parameters in the HV group, the average values of VC, VE and β-CAR in plasma and the activities of SOD, CAT and GSH-Px in RBC in the AL group were significantly decreased (P = 0.0000). The findings in linear regression and correlation analysis for 80 alcoholics showed that with the prolonged drinking duration and increased daily drinking quantity, the values of VC, VE and β-CAR in plasma as well as SOD, CAT and GSH-Px in RBC in the alcoholics were gradually decreased (P = 0.000), representing a respectively significant linear negative correlation. The analysis of stepwise regression and correlation revealed that the drinking duration had the closest correlation with the values of VE in plasma as well as CAT and GSH-Px in RBC, while the daily drinking quantity had the closest correlation with the values of VC, VE and β-CAR in plasma as well as SOD and GSH-Px in RBC. Conclusion\ The findings of the present study suggested that the oxidative stress in the alcoholics became pathologically intensified, leading to potential oxidative damages in their bodies. Therefore, alcoholics should abstain from alcohol drinking, and should take as supplements suitable dosage of antioxidants per day such as VC, VE, β-CAR and others to moderate potential oxidative damages in their bodies.
基金Supported by the National High-Tech Programs(No.2002AA103062, No.2002AA121061 and No.2003AA103520) the Huawei Technologies Co. under contract number YBCN2002001.
文摘A methodology is proposed to handle problem that under equiproble address of packet traffic at the input port, Generalized Shuffle-Exchange Network (GSEN) routes traffic unevenly because of the unbalanced routing tags. The idea is to use routing tag according to probability, which can be evaluated by using Moore-Penrose inverse in matrix analysis. An instance is used to illustrate the idea, and the simulation is done to show the improvement in performance issues.
