Perforation is a pivotal technique employed to establish main flow channels within the reservoir formation at the outset of hydraulic fracturing operations.Optimizing perforation designs is critical for augmenting the...Perforation is a pivotal technique employed to establish main flow channels within the reservoir formation at the outset of hydraulic fracturing operations.Optimizing perforation designs is critical for augmenting the efficacy of hydraulic fracturing and boosting oil or gas production.In this study,we employ a hybrid finite-discrete element method,known as the continuous–discontinuous element method(CDEM),to simulate the initiation of post-perforation hydraulic fractures and to derive enhanced design parameters.The model incorporates the four most prevalent perforation geometries,as delineated in an engineering technical report.Real-world perforations deviate from the ideal cylindrical shape,exhibiting variable cross-sectional profiles that typically manifest as an initial constriction followed by an expansion,a feature consistent across all four perforation types.Our simulations take into account variations in perforation hole geometries,cross-sectional diameters,and perforation lengths.The findings show that perforations generated by the 39g DP3 HMX perforating bullet yield the lowest breakdown pressure,which inversely correlates with increases in sectional diameter and perforation length.Moreover,this study reveals the relationship between breakdown pressure and fracture degree,providing valuable insights for engineers and designers to refine perforation strategies.展开更多
Objective Both sequential embryo transfer(SeET)and double-blastocyst transfer(DBT)can serve as embryo transfer strategies for women with recurrent implantation failure(RIF).This study aims to compare the effects of Se...Objective Both sequential embryo transfer(SeET)and double-blastocyst transfer(DBT)can serve as embryo transfer strategies for women with recurrent implantation failure(RIF).This study aims to compare the effects of SeET and DBT on pregnancy outcomes.Methods Totally,261 frozen-thawed embryo transfer cycles of 243 RIF women were included in this multicenter retrospective analysis.According to different embryo quality and transfer strategies,they were divided into four groups:group A,good-quality SeET(GQ-SeET,n=38 cycles);group B,poor-quality or mixed-quality SeET(PQ/MQ-SeET,n=31 cycles);group C,good-quality DBT(GQ-DBT,n=121 cycles);and group D,poor-quality or mixed-quality DBT(PQ/MQ-DBT,n=71 cycles).The main outcome,clinical pregnancy rate,was compared,and the generalized estimating equation(GEE)model was used to correct potential confounders that might impact pregnancy outcomes.Results GQ-DBT achieved a significantly higher clinical pregnancy rate(aOR 2.588,95%CI 1.267–5.284,P=0.009)and live birth rate(aOR 3.082,95%CI 1.482–6.412,P=0.003)than PQ/MQ-DBT.Similarly,the clinical pregnancy rate was significantly higher in GQ-SeET than in PQ/MQ-SeET(aOR 4.047,95%CI 1.218–13.450,P=0.023).The pregnancy outcomes of GQ-SeET were not significantly different from those of GQ-DBT,and the same results were found between PQ/MQ-SeET and PQ/MQ-DBT.Conclusion SeET relative to DBT did not seem to improve pregnancy outcomes for RIF patients if the embryo quality was comparable between the two groups.Better clinical pregnancy outcomes could be obtained by transferring good-quality embryos,no matter whether in SeET or DBT.Embryo quality plays a more important role in pregnancy outcomes for RIF patients.展开更多
BACKGROUND Cervical intraepithelial neoplasia(CIN)is an important precursor of cervical cancer.Early detection and treatment can reduce the incidence of cervical cancer.AIM To investigate the detection rate of human p...BACKGROUND Cervical intraepithelial neoplasia(CIN)is an important precursor of cervical cancer.Early detection and treatment can reduce the incidence of cervical cancer.AIM To investigate the detection rate of human papillomavirus(HPV)E6/E7 mRNA in cervical tissue of patients with different types of epithelial cell neoplasia(CIN)and its relationship with CIN progression and diagnosis.METHODS One hundred women with HPV infection detected by cervical exfoliation cytology between January 2022 and January 2023 were retrospectively selected.These patients were graded CIN based on colposcopy and cervical pathology.The positive expression rates of HPV E6/E7 mRNA and HPV[polymerase chain reaction(PCR)-reverse dot crossing]were compared among all groups.Patients with HPV E6/E7 mRNA expression in the grade 1 CIN group were followed up for 1 yr.The relationship between atypical squamous epithelium and high malignant epithelial neoplasia was investigated by univariate and multivariate analysis.RESULTS The diagnostic sensitivity,specificity,and sensitivity of PCR-reverse point hybrid ization technology for secondary CIN were 70.41%,70.66%,and 0.714,respectively.Sensitivity and specificity for secondary CIN were 752%and 7853%,respectively,the area under the curve value was 0.789.Logistic Multifactorial model analysis revealed that the HPV positive rates and the HPV E6/E7 mRNA positive rates were independent risk factors of CIN grade I(P<0.05).In CIN grade I patients with positive for HPV E6/E7 mRNA,in its orientation to grade CIN patients,in its orientation to grade CIN patients,at 69.2%,compared with patients negative for HPV E6/E7 mRNA(30.8%),significant difference(P<0.05).CONCLUSION HPV E6/E7 mRNA and HPV(PCR-reverse dot hybrid)positive expression have a close relationship with CINgrade disease progression and is an independent risk factor for high-grade CIN lesions.展开更多
Objective:To explore the clinical efficacy and incidence of hypoglycemia in the treatment of elderly diabetes with glimepiride combined with insulin.Methods:A total of 100 patients diagnosed with diabetes in Qinghai R...Objective:To explore the clinical efficacy and incidence of hypoglycemia in the treatment of elderly diabetes with glimepiride combined with insulin.Methods:A total of 100 patients diagnosed with diabetes in Qinghai Red Cross Hospital from January 2018 to January 2019 were selected and divided into an observation group and a control group according to the order of their visits,with 50 patients in each group.The observation group was treated with glimepiride combined with insulin,while the control group was treated with insulin alone.The blood sugar indicators,including glycated hemoglobin(HbA1c),fasting blood glucose(FBG),and 2-hour postprandial blood glucose(2h PBG),were compared between the two groups.Additionally,the incidence of hypoglycemia was compared,and the causes of hypoglycemia were analyzed and summarized,proposing corresponding countermeasures.Results:The glycated hemoglobin value of the observation group was lower than that of the control group,and the statistical analysis showed a significant difference(t=3.54,P<0.05).The fasting blood glucose value in the observation group was lower than that in the control group,with statistically significant differences(t=4.08,P<0.05).The 2-hour postprandial blood glucose value in the observation group was also lower than that in the control group,with a significant difference(t=3.82,P<0.05).The incidence of hypoglycemia in the observation group was 10%,while it was 56%in the control group,with a statistically significant difference between the two groups(χ^(2)=5.813,P<0.05).Conclusion:The efficacy of glimepiride combined with insulin in the treatment of elderly diabetes is significantly higher than that of insulin alone,with a lower incidence of hypoglycemia.展开更多
Thermal cracking of rocks can significantly affect the durability of underground structures in engineering practices such as geothermal energy extraction,storage of nuclear waste and tunnelling in freezeethaw cycle in...Thermal cracking of rocks can significantly affect the durability of underground structures in engineering practices such as geothermal energy extraction,storage of nuclear waste and tunnelling in freezeethaw cycle induced areas.It is a scenario of strong coupled thermomechanical process involving discontinuity behaviours of rocks.In this context,a numerical model was proposed to investigate the thermal cracking of rocks,in a framework of the continuous-discontinuous element method(CDEM)for efficiently capturing the initiation and propagation of multiple cracks.A simplex integration strategy was adopted to account for the influences of temperature-dependent material properties.Several benchmark tests were considered and the obtained results were compared with analytical solutions and numerical results from the literature.The results show that the fracture degree of the cases when considering temperature-dependent material parameters had 10%differences approximately compared with the cases with constant parameters.展开更多
Continuum-based discrete element method(CDEM)is an explicit numerical method used for simulation of progressive failure of geological body.To improve the efficiency of contact detection and simplify the calculation st...Continuum-based discrete element method(CDEM)is an explicit numerical method used for simulation of progressive failure of geological body.To improve the efficiency of contact detection and simplify the calculation steps for contact forces,semi-spring and semi-edge are introduced in calculation.Semispring is derived from block vertex,and formed by indenting the block vertex into each face(24semisprings for a hexahedral element).The formation process of semi-edge is the same as that of semi-spring(24semi-edges for a hexahedral element).Based on the semi-springs and semi-edges,a new type of combined contact model is presented.According to this model,six contact types could be reduced to two,i.e.the semi-spring target face contact and semi-edge target edge contact.By the combined model,the contact force could be calculated directly(the information of contact type is not necessary),and the failure judgment could be executed in a straightforward way(each semi-spring and semi-edge own their characteristic areas).The algorithm has been successfully programmed in C++program.Some simple numerical cases are presented to show the validity and accuracy of this model.Finally,the failure mode,sliding distance and critical friction angle of Jiweishan landslide are studied with the combined model.展开更多
The aboveground biomass(AGB)of shrubs and small trees is the main component for the productivity and carbon storage of understory vegetation in subtropical secondary forests.However,few allometric models exist to accu...The aboveground biomass(AGB)of shrubs and small trees is the main component for the productivity and carbon storage of understory vegetation in subtropical secondary forests.However,few allometric models exist to accurately evaluate understory biomass.To estimate the AGB of five common shrub(diameter at base<5 cm,<5 m high)and one small tree species(<8 m high,trees’s seedling),206 individuals were harvested and species-specific and multi-species allometric models developed based on four predictors,height(H),stem diameter(D),crown area(Ca),and wood density(ρ).As expected,the six species possessed greater biomass in their stems compared with branches,with the lowest biomass in the leaves.Species-specific allometric models that employed stem diameter and the combined variables of D~2H andρDH as predictors accurately estimated the components and total AGB,with R^(2) values from 0.602 and 0.971.A multi-species shrub allometric model revealed that wood density×diameter×height(ρDH)was the best predictor,with R^(2) values ranging from between 0.81 and 0.89 for the components and total AGB,respectively.These results indicated that height(H)and diameter(D)were effective predictors for the models to estimate the AGB of the six species,and the introduction of wood density(ρ)improved their accuracy.The optimal models selected in this study could be applied to estimate the biomass of shrubs and small trees in subtropical regions.展开更多
To simulate the progressive failure of slope,a block particle coupled model is introduced.Particle oriented cell mapping(POCM)algorithm is used to enhance the search efficiency,and particlepoint,particle-edge,particle...To simulate the progressive failure of slope,a block particle coupled model is introduced.Particle oriented cell mapping(POCM)algorithm is used to enhance the search efficiency,and particlepoint,particle-edge,particle-face contact detecting method is adopted to establish contact pair between particles and blocks precisely.Strain softening Mohr Coulomb model with tensile cutoff is adopted for blocks,and brittle Mohr Coulomb model is used for particles.The particle-block replacement approach is used to describe the fracture and fragmentation process of continuum media.Once the cohesion or tensile strength of one block reaches zero,the block will be deleted,and particles are generated at the same place with all information inherited from the deleted block.Some numerical cases related to landslides demonstrate the precision and rationality of the coupled model.展开更多
Two new diphyllin glycosides, mananthoside A (1) and B (2), together with six known compounds. were isolated from the ethanolic extract of the whole plants of Mananthes patentiflora. Their structures were determined o...Two new diphyllin glycosides, mananthoside A (1) and B (2), together with six known compounds. were isolated from the ethanolic extract of the whole plants of Mananthes patentiflora. Their structures were determined on the basis of chemical and spectral evidences.展开更多
BACKGROUND Carotid body tumor(CBT)is a chemoreceptor tumor located in the carotid body,accounting for approximately 0.22%of head and neck tumors.Surgery is the main treatment method for the disease.CASE SUMMARY We rev...BACKGROUND Carotid body tumor(CBT)is a chemoreceptor tumor located in the carotid body,accounting for approximately 0.22%of head and neck tumors.Surgery is the main treatment method for the disease.CASE SUMMARY We reviewed the diagnosis and treatment of one patient who had postoperative secondary aggravation of obstructive sleep apnea–hypopnea syndrome(OSAHS)and hypoxia after surgical resection of bilateral CBTs.This patient was admitted,and relevant laboratory and imaging examinations,and polysomnography(PSG)were performed.After the definitive diagnosis,continuous positive airway pressure(CPAP)treatment was given,which achieved good efficacy.CONCLUSION This case suggested that aggravation of OSAHS and hypoxemia is possibly caused by the postoperative complications after bilateral CBTs,and diagnosis by PSG and CPAP treatment are helpful for this patient.展开更多
In this paper,we investigated the effect of post-gate annealing(PGA)on reverse gate leakage and the reverse bias reliability of Al_(0.23)Ga_(0.77)N/GaN high electron mobility transistors(HEMTs).We found that the Poole...In this paper,we investigated the effect of post-gate annealing(PGA)on reverse gate leakage and the reverse bias reliability of Al_(0.23)Ga_(0.77)N/GaN high electron mobility transistors(HEMTs).We found that the Poole-Frenkel(PF)emission is dominant in the reverse gate leakage current at the low reverse bias region(V_(th)<V_(G)<0 V)for the unannealed and annealed HEMTs.The emission barrier height of HEMT is increased from 0.139 to 0.256 eV after the PGA process,which results in a reduction of the reverse leakage current by more than one order.Besides,the reverse step stress was conducted to study the gate reliability of both HEMTs.After the stress,the unannealed HEMT shows a higher reverse leakage current due to the permanent damage of the Schottky gate.In contrast,the annealed HEMT shows a little change in reverse leakage current.This indicates that the PGA can reduce the reverse gate leakage and improve the gate reliability.展开更多
State-of-the-art AlGaN/GaN high electron mobility structures were grown on semi-insulating 4H-SiC substrates by MOCVD and X-band microwave power high electron mobility transistors were fabricated and characterized.Hal...State-of-the-art AlGaN/GaN high electron mobility structures were grown on semi-insulating 4H-SiC substrates by MOCVD and X-band microwave power high electron mobility transistors were fabricated and characterized.Hall mobility of 2291.1 cm^(2)/(V·s)and two-dimensional electron gas density of 9.954×10^(12)cm^(-2)were achieved at 300 K.The HEMT devices with a 0.45-μm gate length exhibited maximum drain current density as high as 1039.6 mA/mm and peak extrinsic transconductance of 229.7 mS/mm.The f_(T)of 30.89 GHz and f_(max)of 38.71 GHz were measured on the device.Load-pull measurements were performed and analyzed under(-3.5,28)V,(-3.5,34)V and(-3.5,40)V gate/drain direct current bias in class-AB,respectively.The uncooled device showed high linear power gain of 17.04 dB and high power-added efficiency of 50.56%at 8 GHz when drain biased at(-3.5,28)V.In addition,when drain biased at(-3.5,40)V,the device exhibited a saturation output power dens-ity up to 6.21 W/mm at 8 GHz,with a power gain of 11.94 dB and a power-added efficiency of 39.56%.Furthermore,the low f_(max)/f_(T)ratio and the variation of the power sweep of the device at 8 GHz with drain bias voltage were analyzed.展开更多
In order to discuss the relationship between the characteristics of plant communities and the content of topsoil organic matter under the condition of two-season sedentary grazing, authors of this paper selected a Sti...In order to discuss the relationship between the characteristics of plant communities and the content of topsoil organic matter under the condition of two-season sedentary grazing, authors of this paper selected a Stipa krylovii steppe for research and studied the plant community characteristics and the topsoil organic matter content. The results showed that in the sedentary grazing area, the perennial plant species decreased, the annual plant species increased, and the topsoil organic matter content decreased. There were a negative correlation between plant biomass and topsoil organic matter content, and a positive correlation between total coverage and topsoil organic matter content. The change of plant community characteristics in the sedentary grazing area was related to the implementation of the system of transferring the pasture use rights to the herdsmen and controlled grazing.展开更多
Different monolayers (ML) of Fe atoms were deposited on NiO (001) substrates or NiO underlayers using molecular beam epitaxy (MBE), pulse laser deposition (PLD), and magnetron sputtering (MS). The magnetic p...Different monolayers (ML) of Fe atoms were deposited on NiO (001) substrates or NiO underlayers using molecular beam epitaxy (MBE), pulse laser deposition (PLD), and magnetron sputtering (MS). The magnetic properties and microstructure of the films were studied. The apparent magnetic dead layer (MDL) is found to exist at the NiO/Fe interfaces of the MBE sample (about 2 ML MDL), the PLD sample (about 3 ML MDL), and the MS sample (about 4 ML MDL). X-ray photoelectron spectroscopy indicates the presence of ionic Fe (Fe2+ or Fe3+) and metallic Ni at the NiO/Fe interfaces, which may be due to the chemical reactions between Fe and NiO layers. This also leads to the formation of MDL. The thickness of the MDL and the reaction products are related with the deposition energy of the atoms on the substrates. The interfacial reactions are effectively suppressed by inserting a thin Pt layer at the NiO/Fe interface.展开更多
基金support from the National Natural Science Foundation of China(Grant Nos.52178324,12102059)the China Postdoctoral Science Foundation(Grant No.2023M743604)+1 种基金the Beijing Natural Science Foundation(Grant No.3212027),the National Key R&D Program of China(Grant No.2023YFC3007203)the 2019 Foreign Experts Plan of Hebei Province.
文摘Perforation is a pivotal technique employed to establish main flow channels within the reservoir formation at the outset of hydraulic fracturing operations.Optimizing perforation designs is critical for augmenting the efficacy of hydraulic fracturing and boosting oil or gas production.In this study,we employ a hybrid finite-discrete element method,known as the continuous–discontinuous element method(CDEM),to simulate the initiation of post-perforation hydraulic fractures and to derive enhanced design parameters.The model incorporates the four most prevalent perforation geometries,as delineated in an engineering technical report.Real-world perforations deviate from the ideal cylindrical shape,exhibiting variable cross-sectional profiles that typically manifest as an initial constriction followed by an expansion,a feature consistent across all four perforation types.Our simulations take into account variations in perforation hole geometries,cross-sectional diameters,and perforation lengths.The findings show that perforations generated by the 39g DP3 HMX perforating bullet yield the lowest breakdown pressure,which inversely correlates with increases in sectional diameter and perforation length.Moreover,this study reveals the relationship between breakdown pressure and fracture degree,providing valuable insights for engineers and designers to refine perforation strategies.
文摘Objective Both sequential embryo transfer(SeET)and double-blastocyst transfer(DBT)can serve as embryo transfer strategies for women with recurrent implantation failure(RIF).This study aims to compare the effects of SeET and DBT on pregnancy outcomes.Methods Totally,261 frozen-thawed embryo transfer cycles of 243 RIF women were included in this multicenter retrospective analysis.According to different embryo quality and transfer strategies,they were divided into four groups:group A,good-quality SeET(GQ-SeET,n=38 cycles);group B,poor-quality or mixed-quality SeET(PQ/MQ-SeET,n=31 cycles);group C,good-quality DBT(GQ-DBT,n=121 cycles);and group D,poor-quality or mixed-quality DBT(PQ/MQ-DBT,n=71 cycles).The main outcome,clinical pregnancy rate,was compared,and the generalized estimating equation(GEE)model was used to correct potential confounders that might impact pregnancy outcomes.Results GQ-DBT achieved a significantly higher clinical pregnancy rate(aOR 2.588,95%CI 1.267–5.284,P=0.009)and live birth rate(aOR 3.082,95%CI 1.482–6.412,P=0.003)than PQ/MQ-DBT.Similarly,the clinical pregnancy rate was significantly higher in GQ-SeET than in PQ/MQ-SeET(aOR 4.047,95%CI 1.218–13.450,P=0.023).The pregnancy outcomes of GQ-SeET were not significantly different from those of GQ-DBT,and the same results were found between PQ/MQ-SeET and PQ/MQ-DBT.Conclusion SeET relative to DBT did not seem to improve pregnancy outcomes for RIF patients if the embryo quality was comparable between the two groups.Better clinical pregnancy outcomes could be obtained by transferring good-quality embryos,no matter whether in SeET or DBT.Embryo quality plays a more important role in pregnancy outcomes for RIF patients.
基金Scientific Research Project of Hubei Provincial Health Commission,No.WJ2021M189。
文摘BACKGROUND Cervical intraepithelial neoplasia(CIN)is an important precursor of cervical cancer.Early detection and treatment can reduce the incidence of cervical cancer.AIM To investigate the detection rate of human papillomavirus(HPV)E6/E7 mRNA in cervical tissue of patients with different types of epithelial cell neoplasia(CIN)and its relationship with CIN progression and diagnosis.METHODS One hundred women with HPV infection detected by cervical exfoliation cytology between January 2022 and January 2023 were retrospectively selected.These patients were graded CIN based on colposcopy and cervical pathology.The positive expression rates of HPV E6/E7 mRNA and HPV[polymerase chain reaction(PCR)-reverse dot crossing]were compared among all groups.Patients with HPV E6/E7 mRNA expression in the grade 1 CIN group were followed up for 1 yr.The relationship between atypical squamous epithelium and high malignant epithelial neoplasia was investigated by univariate and multivariate analysis.RESULTS The diagnostic sensitivity,specificity,and sensitivity of PCR-reverse point hybrid ization technology for secondary CIN were 70.41%,70.66%,and 0.714,respectively.Sensitivity and specificity for secondary CIN were 752%and 7853%,respectively,the area under the curve value was 0.789.Logistic Multifactorial model analysis revealed that the HPV positive rates and the HPV E6/E7 mRNA positive rates were independent risk factors of CIN grade I(P<0.05).In CIN grade I patients with positive for HPV E6/E7 mRNA,in its orientation to grade CIN patients,in its orientation to grade CIN patients,at 69.2%,compared with patients negative for HPV E6/E7 mRNA(30.8%),significant difference(P<0.05).CONCLUSION HPV E6/E7 mRNA and HPV(PCR-reverse dot hybrid)positive expression have a close relationship with CINgrade disease progression and is an independent risk factor for high-grade CIN lesions.
文摘Objective:To explore the clinical efficacy and incidence of hypoglycemia in the treatment of elderly diabetes with glimepiride combined with insulin.Methods:A total of 100 patients diagnosed with diabetes in Qinghai Red Cross Hospital from January 2018 to January 2019 were selected and divided into an observation group and a control group according to the order of their visits,with 50 patients in each group.The observation group was treated with glimepiride combined with insulin,while the control group was treated with insulin alone.The blood sugar indicators,including glycated hemoglobin(HbA1c),fasting blood glucose(FBG),and 2-hour postprandial blood glucose(2h PBG),were compared between the two groups.Additionally,the incidence of hypoglycemia was compared,and the causes of hypoglycemia were analyzed and summarized,proposing corresponding countermeasures.Results:The glycated hemoglobin value of the observation group was lower than that of the control group,and the statistical analysis showed a significant difference(t=3.54,P<0.05).The fasting blood glucose value in the observation group was lower than that in the control group,with statistically significant differences(t=4.08,P<0.05).The 2-hour postprandial blood glucose value in the observation group was also lower than that in the control group,with a significant difference(t=3.82,P<0.05).The incidence of hypoglycemia in the observation group was 10%,while it was 56%in the control group,with a statistically significant difference between the two groups(χ^(2)=5.813,P<0.05).Conclusion:The efficacy of glimepiride combined with insulin in the treatment of elderly diabetes is significantly higher than that of insulin alone,with a lower incidence of hypoglycemia.
基金the financial support from the Natural Science Foundation of Hebei Province(Grant No.E2020050012)the National Natural Science Foundation of China(NSFC)(Grant No.52178324)the National Key Research and Development Project of China,the Ministry of Science and Technology of China(Grant No.2018YFC1505504).
文摘Thermal cracking of rocks can significantly affect the durability of underground structures in engineering practices such as geothermal energy extraction,storage of nuclear waste and tunnelling in freezeethaw cycle induced areas.It is a scenario of strong coupled thermomechanical process involving discontinuity behaviours of rocks.In this context,a numerical model was proposed to investigate the thermal cracking of rocks,in a framework of the continuous-discontinuous element method(CDEM)for efficiently capturing the initiation and propagation of multiple cracks.A simplex integration strategy was adopted to account for the influences of temperature-dependent material properties.Several benchmark tests were considered and the obtained results were compared with analytical solutions and numerical results from the literature.The results show that the fracture degree of the cases when considering temperature-dependent material parameters had 10%differences approximately compared with the cases with constant parameters.
基金the National Basic Research Program of the Ministry of Science and Technology of China (Grant No. 2010CB731506)the National Key Technology Research and Development Program of the Ministry of Science and Technology of China (Grant No. 2012BAK10B01)the Youth Science Fund of National Natural Science Foundation of China (Grant No. 11302230)
文摘Continuum-based discrete element method(CDEM)is an explicit numerical method used for simulation of progressive failure of geological body.To improve the efficiency of contact detection and simplify the calculation steps for contact forces,semi-spring and semi-edge are introduced in calculation.Semispring is derived from block vertex,and formed by indenting the block vertex into each face(24semisprings for a hexahedral element).The formation process of semi-edge is the same as that of semi-spring(24semi-edges for a hexahedral element).Based on the semi-springs and semi-edges,a new type of combined contact model is presented.According to this model,six contact types could be reduced to two,i.e.the semi-spring target face contact and semi-edge target edge contact.By the combined model,the contact force could be calculated directly(the information of contact type is not necessary),and the failure judgment could be executed in a straightforward way(each semi-spring and semi-edge own their characteristic areas).The algorithm has been successfully programmed in C++program.Some simple numerical cases are presented to show the validity and accuracy of this model.Finally,the failure mode,sliding distance and critical friction angle of Jiweishan landslide are studied with the combined model.
基金supported by the Special Major Science and Technology Project of Anhui Province(S202103b06020066)the 2020 Annual Graduate Innovation Fund of Anhui Agricultural University(2020YSJ-21)。
文摘The aboveground biomass(AGB)of shrubs and small trees is the main component for the productivity and carbon storage of understory vegetation in subtropical secondary forests.However,few allometric models exist to accurately evaluate understory biomass.To estimate the AGB of five common shrub(diameter at base<5 cm,<5 m high)and one small tree species(<8 m high,trees’s seedling),206 individuals were harvested and species-specific and multi-species allometric models developed based on four predictors,height(H),stem diameter(D),crown area(Ca),and wood density(ρ).As expected,the six species possessed greater biomass in their stems compared with branches,with the lowest biomass in the leaves.Species-specific allometric models that employed stem diameter and the combined variables of D~2H andρDH as predictors accurately estimated the components and total AGB,with R^(2) values from 0.602 and 0.971.A multi-species shrub allometric model revealed that wood density×diameter×height(ρDH)was the best predictor,with R^(2) values ranging from between 0.81 and 0.89 for the components and total AGB,respectively.These results indicated that height(H)and diameter(D)were effective predictors for the models to estimate the AGB of the six species,and the introduction of wood density(ρ)improved their accuracy.The optimal models selected in this study could be applied to estimate the biomass of shrubs and small trees in subtropical regions.
基金supported by the National Key Research and Development Project of China,the Ministry of Science and Technology of China(Grant 2018YFC1505504)。
文摘To simulate the progressive failure of slope,a block particle coupled model is introduced.Particle oriented cell mapping(POCM)algorithm is used to enhance the search efficiency,and particlepoint,particle-edge,particle-face contact detecting method is adopted to establish contact pair between particles and blocks precisely.Strain softening Mohr Coulomb model with tensile cutoff is adopted for blocks,and brittle Mohr Coulomb model is used for particles.The particle-block replacement approach is used to describe the fracture and fragmentation process of continuum media.Once the cohesion or tensile strength of one block reaches zero,the block will be deleted,and particles are generated at the same place with all information inherited from the deleted block.Some numerical cases related to landslides demonstrate the precision and rationality of the coupled model.
基金the financial support of Di-Ao Science Foundation.
文摘Two new diphyllin glycosides, mananthoside A (1) and B (2), together with six known compounds. were isolated from the ethanolic extract of the whole plants of Mananthes patentiflora. Their structures were determined on the basis of chemical and spectral evidences.
文摘BACKGROUND Carotid body tumor(CBT)is a chemoreceptor tumor located in the carotid body,accounting for approximately 0.22%of head and neck tumors.Surgery is the main treatment method for the disease.CASE SUMMARY We reviewed the diagnosis and treatment of one patient who had postoperative secondary aggravation of obstructive sleep apnea–hypopnea syndrome(OSAHS)and hypoxia after surgical resection of bilateral CBTs.This patient was admitted,and relevant laboratory and imaging examinations,and polysomnography(PSG)were performed.After the definitive diagnosis,continuous positive airway pressure(CPAP)treatment was given,which achieved good efficacy.CONCLUSION This case suggested that aggravation of OSAHS and hypoxemia is possibly caused by the postoperative complications after bilateral CBTs,and diagnosis by PSG and CPAP treatment are helpful for this patient.
基金supported by the National Key Research and Development Program of China(2017YFB0402900)the National Natural Sciences Foundation of China(62074144).
文摘In this paper,we investigated the effect of post-gate annealing(PGA)on reverse gate leakage and the reverse bias reliability of Al_(0.23)Ga_(0.77)N/GaN high electron mobility transistors(HEMTs).We found that the Poole-Frenkel(PF)emission is dominant in the reverse gate leakage current at the low reverse bias region(V_(th)<V_(G)<0 V)for the unannealed and annealed HEMTs.The emission barrier height of HEMT is increased from 0.139 to 0.256 eV after the PGA process,which results in a reduction of the reverse leakage current by more than one order.Besides,the reverse step stress was conducted to study the gate reliability of both HEMTs.After the stress,the unannealed HEMT shows a higher reverse leakage current due to the permanent damage of the Schottky gate.In contrast,the annealed HEMT shows a little change in reverse leakage current.This indicates that the PGA can reduce the reverse gate leakage and improve the gate reliability.
基金supported by the National Key Research and Development Program of China(2017YFB0402900)the Key-Area Research and Development Program of Guangdong Province(2019B010126001)+3 种基金the Natural Science Foundation for Distinguished Young Scholars of Shandong Province(ZR2019JQ01)the National Natural Sciences Foundation of China(62074144,52022052,62004118)Key R&D plan of Shandong Province(2019JMRH0901,2019JMRH0201)the Natural Science Foundation of Shandong Province(ZR2019BEM030,ZR2019BEM011).
文摘State-of-the-art AlGaN/GaN high electron mobility structures were grown on semi-insulating 4H-SiC substrates by MOCVD and X-band microwave power high electron mobility transistors were fabricated and characterized.Hall mobility of 2291.1 cm^(2)/(V·s)and two-dimensional electron gas density of 9.954×10^(12)cm^(-2)were achieved at 300 K.The HEMT devices with a 0.45-μm gate length exhibited maximum drain current density as high as 1039.6 mA/mm and peak extrinsic transconductance of 229.7 mS/mm.The f_(T)of 30.89 GHz and f_(max)of 38.71 GHz were measured on the device.Load-pull measurements were performed and analyzed under(-3.5,28)V,(-3.5,34)V and(-3.5,40)V gate/drain direct current bias in class-AB,respectively.The uncooled device showed high linear power gain of 17.04 dB and high power-added efficiency of 50.56%at 8 GHz when drain biased at(-3.5,28)V.In addition,when drain biased at(-3.5,40)V,the device exhibited a saturation output power dens-ity up to 6.21 W/mm at 8 GHz,with a power gain of 11.94 dB and a power-added efficiency of 39.56%.Furthermore,the low f_(max)/f_(T)ratio and the variation of the power sweep of the device at 8 GHz with drain bias voltage were analyzed.
基金Sponsored by National Natural Science Foundation of China(41561009,41561050)Scientific Research Innovation Funds for Graduates in Inner Mongolia Normal University(CXJJ17101)
文摘In order to discuss the relationship between the characteristics of plant communities and the content of topsoil organic matter under the condition of two-season sedentary grazing, authors of this paper selected a Stipa krylovii steppe for research and studied the plant community characteristics and the topsoil organic matter content. The results showed that in the sedentary grazing area, the perennial plant species decreased, the annual plant species increased, and the topsoil organic matter content decreased. There were a negative correlation between plant biomass and topsoil organic matter content, and a positive correlation between total coverage and topsoil organic matter content. The change of plant community characteristics in the sedentary grazing area was related to the implementation of the system of transferring the pasture use rights to the herdsmen and controlled grazing.
基金supported by the National Natural Science Foundation of China (Nos.50871014, 50831002, 50971021, and 50901007)the Funding Project for Academic Human Resources Development in Institutions of Higher Learning under the Jurisdiction of Beijing Municipality (No.PHR201007122)
文摘Different monolayers (ML) of Fe atoms were deposited on NiO (001) substrates or NiO underlayers using molecular beam epitaxy (MBE), pulse laser deposition (PLD), and magnetron sputtering (MS). The magnetic properties and microstructure of the films were studied. The apparent magnetic dead layer (MDL) is found to exist at the NiO/Fe interfaces of the MBE sample (about 2 ML MDL), the PLD sample (about 3 ML MDL), and the MS sample (about 4 ML MDL). X-ray photoelectron spectroscopy indicates the presence of ionic Fe (Fe2+ or Fe3+) and metallic Ni at the NiO/Fe interfaces, which may be due to the chemical reactions between Fe and NiO layers. This also leads to the formation of MDL. The thickness of the MDL and the reaction products are related with the deposition energy of the atoms on the substrates. The interfacial reactions are effectively suppressed by inserting a thin Pt layer at the NiO/Fe interface.