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Synthesis of N1-Substituted-3-aryl-4-alkyl-4, 5-dihydro-1H-1-pyra-zolethiocarboxamide as Novel Small Molecule Inhibitors of Cysteine Protease of T.cruzi
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作者 chunguo XiaoHuiDU 《Chinese Chemical Letters》 SCIE CAS CSCD 2002年第11期1043-1046,共4页
A series of N1-substituted-3-aryl-4-alkyl-4, 5-dihydro-1H-1-pyrazolethiocarboxamide were prepared from the Mannich bases of aryl ketones in good yields. Some derivatives were found to be active against the cysteine p... A series of N1-substituted-3-aryl-4-alkyl-4, 5-dihydro-1H-1-pyrazolethiocarboxamide were prepared from the Mannich bases of aryl ketones in good yields. Some derivatives were found to be active against the cysteine protease of T.cruzi.. 展开更多
关键词 N1-substituted-3-aryl-4-alkyl-4 5-dihydro-1H-1-pyrazolethiocarboxamide synthesis T.cruzi. cysteine protease inhibitor.
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