Investigating the charge transfer mechanism of ZnSe QD/COF S-scheme photocatalyst for H_(2)O_(2) production by using femtosecond transient absorption spectroscopy

Hydrogen peroxide(H_(2)O_(2))has gained widespread attention as a versatile oxidant and a mild disin-fectant.Here,an electrostatic self-assembly method is applied to couple ZnSe quantum dots(QDs)with a flower-like covalent organic framework(COF)to form a step-scheme(S-scheme)photocata-lyst for H_(2)O_(2)production.The as-prepared S-scheme photocatalyst exhibits a broad light absorption range with an edge at 810 nm owing to the synergistic effect between the ZnSe QDs and COF.The S-scheme charge-carrier transfer mechanism is validated by performing Fermi level calculations and in-situ X-ray photoelectron and femtosecond transient absorption spectroscopies.Photolumi-nescence,time-resolved photoluminescence,photocurrent response,electrochemical impedance spectroscopy,and electron paramagnetic resonance results show that the S-scheme heterojunction not only promotes charge carrier separation but also boosts the redox ability,resulting in enhanced photocatalytic performance.Remarkably,a 10%-ZnSe QD/COF has excellent photocatalytic H_(2)O_(2)-production activity,and the optimal S-scheme composite with ethanol as the hole scavenger yields a H_(2)O_(2)-production rate of 1895 mol g^(-1)h^(-1).This study presents an example of a high-performance organic/inorganic S-scheme photocatalyst for H_(2)O_(2)production.

Whole‑genome transcriptome and DNA methylation dynamics of pre‑implantation embryos reveal progression of embryonic genome activation in buffaloes

Background During mammalian pre-implantation embryonic development(PED),the process of maternal-to-zygote transition(MZT)is well orchestrated by epigenetic modification and gene sequential expression,and it is related to the embryonic genome activation(EGA).During MZT,the embryos are sensitive to the environment and easy to arrest at this stage in vitro.However,the timing and regulation mechanism of EGA in buffaloes remain obscure.Results Buffalo pre-implantation embryos were subjected to trace cell based RNA-seq and whole-genome bisulfite sequencing(WGBS)to draw landscapes of transcription and DNA-methylation.Four typical developmental steps were classified during buffalo PED.Buffalo major EGA was identified at the 16-cell stage by the comprehensive analy-sis of gene expression and DNA methylation dynamics.By weighted gene co-expression network analysis,stage-spe-cific modules were identified during buffalo maternal-to-zygotic transition,and key signaling pathways and biological process events were further revealed.Programmed and continuous activation of these pathways was necessary for success of buffalo EGA.In addition,the hub gene,CDK1,was identified to play a critical role in buffalo EGA.Conclusions Our study provides a landscape of transcription and DNA methylation in buffalo PED and reveals deeply the molecular mechanism of the buffalo EGA and genetic programming during buffalo MZT.It will lay a foundation for improving the in vitro development of buffalo embryos.

Stability analysis of the projectile based on random center manifold reduction

The center manifold method has been widely used in the field of stochastic dynamics as a dimensionality reduction method.This paper studied the angular motion stability of a projectile system under random disturbances.The random bifurcation of the projectile is studied using the idea of the Routh-Hurwitz stability criterion,the center manifold reduction,and the polar coordinates transformation.Then,an approximate analytical presentation for the stationary probability density function is found from the related Fokker–Planck equation.From the results,the random dynamical system of projectile generates three different dynamical behaviors with the changes of the bifurcation parameter and the noise strength,which can be a reference for projectile design.

Study on the demand for public health professional after the COVID-19 epidemic in Zhejiang Province, China: A survey based on human-machine collaboration

To understand the needs of public health institutions in Zhejiang Province,China for public health personnel,and provide basis for training public health personnel.Methods:512 public health institutions in Zhejiang Province were randomly selected from different levels and regions,and the number of ublic health professional and the demand for professional ability were investigated by questionnaire.Results:The preventive medicine personnel in public health institutions in Zhejiang Province are insufficient;There is a certain disjunction or dislocation between the abilities and needs of public health professional;The way of continuing education for public health professional is single and the opportunities are few.Conclusion:Zhejiang Province should appropriately expand the enrollment of preventive medicine majors,especially high-level preventive medicine talents,deepen the education and teaching reform of preventive medicine majors,and strengthen the continuing education and training of public health professional to meet the needs of public health services after the COVID-19 epidemic.

教师主观幸福感量表的中文修订

目的:检验教师主观幸福感量表(Teacher Subjective Well-being Questionnaire,TSWQ)中文修订版信度、效度及其跨教师性别、跨任教学段的测量等值性。方法:应用中文版TSWQ对来自全国9省份56所中学的1463名教师进行测量,以中小学教师职业倦怠量表和特拉华校园氛围量表-教工卷为效标工具,一个月后随机抽取55名教师进行重测。结果:(1)验证性因素分析结果支持一阶二因子模型。(2)中文版TSWQ总分与教师校园氛围感知、个人成就感显著正相关(r=0.465,P<0.01;r=0.416,P<0.01),与情绪衰竭、非人性化显著负相关(r=-0.226,P<0.01;r=-0.232,P<0.01)。(3)中文版TSWQ总量表的Cronbach’sα系数为0.898,四周后的重测信度为0.813。(4)多组验证性因素分析结果显示,中文版TSWQ跨性别和跨任教学段的测量等值性假设成立。(5)在教师主观幸福感量表的教学效能感维度存在显著性别差异,男教师教学效能感优于女教师。结论:中文版TSWQ信度与效度良好,可在不同教师性别、任教学段之间进行跨组比较,是研究我国教师主观幸福感的可靠工具。

《乡村教师支持计划》支持下乡村教师职业幸福感建构

乡村教师职业幸福感程度持续性低的表现有:自感在乡村教书没出息,常叹难以融入乡村生活,为不能获得尊重而失落,疲于应付多种教育任务。乡村教师职业幸福感低的关键原因是:角色价值模糊,职业认同程度较低;乡土体验较浅,情怀链接没有建立;职业酬薪一般,社会地位不被认可;问题意识不足,缺乏职业发展动力。在《乡村教师支持计划》的支持下乡村教师职业幸福感建构途径如下:拥编制、扩流动,促进乡村教师角色价值认同;补师资、增荣誉,塑造乡村教师朴素乡土情怀;上职称、升待遇,提高乡村教师应有社会地位;修师德、增能力,支持乡村教师持续专业成长。

Primary metabolite contents are correlated with seed protein and oil traits in near-isogenic lines of soybean

Soybean(Glycine max[L.]Merr.)is an important source of human dietary protein and vegetable oil.A strong negative correlation between protein and oil contents has hindered efforts to improve soybean seed quality.The metabolic and genetic bases of soybean seed composition remain elusive.We evaluated metabolic diversity in a soybean near-isogenic line(NIL)population derived from parents(JD12 and CMSD)with contrasting seed oil contents.Using GC-TOF/MS,we compared seed primary metabolites of high protein/low oil lines,low protein/high oil lines,and their parents.Principal-components analysis showed that metabolic profiles of all progeny lines could be discriminated based on protein and oil contents.Univariate analysis revealed wide variation and transgressive segregation of metabolites in the population.Twenty-eight annotated metabolites,in particular free asparagine,free 3-cyanoalanine,and L-malic acid,were correlated with seed protein content or seed oil content or seed protein and oil content.These results shed light on the metabolic and genetic basis of soybean seed composition.

Prevention and Control of Perioperative Incision Infection in Patients Undergoing Day Cataract Surgery

Purpose:To explore the effects of the prevention and control of perioperative incision infection on the quality of day cataract surgery.Methods:.The nursing care and efficacy of 5087 patients undergoing day cataract surgery between October 2012 and October 2013 were retrospectively reviewed. The disinfection and isolation guidance was established for perioperative prevention and control of infection,.topical administration of ocular agents, reexamination and healthcare instruction, and alternative measures were taken.Results: All 5087 patients successfully underwent day surgery of phacoemulsification combined with intraocular lens implantation. All cases recovered without incision infection.Conclusion: Preoperative preparation, and intraoperative and postoperative prevention and control of infection serve as vital measures for effectively avoiding the incidence of incision infection in patients undergoing day cataract surgery.

H_(2)O_(2)mediates transcriptome reprogramming during Soybean mosaic virus-induced callose deposition in soybean

The main defense response to Soybean mosaic virus(SMV)infection in soybean[Glycine max(L.)Merr.]is thought to be blockage of intercellular virus transport by callose deposition on plasmodesmata.But the specific regulatory mechanism remains largely unknown.In this study,we found that hydrogen peroxide(H_(2)O_(2))signal downstream of NO was associated with the regulation of callose accumulation.Abundant H_(2)O_(2)was produced on the cell membrane and cell wall in the incompatible combination of soybean cultivar Jidou 7 and SMV strain N3,whereas no obvious H_(2)O_(2)was observed in the compatible combination of Jidou 7 and strain SC-8.When H_(2)O_(2)production was inhibited,callose accumulation induced by SMV infection decreased to a level insufficient to restrict virus transport in the incompatible combination.The H_(2)O_(2)-associated transcriptome dynamics of soybean during SMV infection was investigated.Transcriptome and functional analysis using virus-induced gene silencing showed that Gm SEOB and Gm PAP27,two genes regulated by H_(2)O_(2),functioned in resistance by positively regulating the accumulation of callose in response to SMV infection.These results lay a foundation for further research on the signal transduction and molecular regulation of callose deposition during soybean resistance to SMV infection.

A Simple Cement Hydration Model Considering the Influences ofWater-to-Cement Ratio and Mineral Composition

A simple hydration model is used here by taking the composition of the cement and the initial water: cementratio (w/c) into account explicitly. Its conceptual basis is a combination of the Avrami equation and Bentz’s modelbased on simple spatial considerations. In this model, the Avrami equation determines the initial reaction, andBentz’s model describes the following hydration stage. The model favors engineers for it relies on one experimentalparameter and has a reliable approximation in the practice.

Validity and reliability of the Brain Health Self-Efficacy Scale for the elderly

Background With the rapid increase in ageing population,China is confronted with the daunting challenge of a growing number of patients with neurocognitive disorders(NCDs).This trend makes the maintenance of self-health and early intervention essential,highlighting the need for a tool that assesses self-efficacy of older adults in maintaining brain health or cognitive function.Aim This study aimed to design the Brain Health Self-Efficacy Scale(BHSES)to measure elderly individuals'attitudes to NCDs,motivations and future plans for controlling risks.The psychometric properties of BHSES have been validated.Methods Based on the current literature and relevant models,a 19-item scale was created during the first stage.A total of 660 older adults in the Yinhang community of Shanghai were included.The statistical approaches of item analysis,exploratory factor analysis(EFA),confirmatory factor analysis(CFA),criterion-related validity and reliability test were used to evaluate the quality of BHSES.In addition,the Geriatric Depression Scale(GDS)and the Self-Rating Anxiety Scale(SAS)were used as criteria to test the criterion-related validity.Results To test item differentiation,the study adopted item analysis and excluded item 8.Selecting a random half of the sample for EFA,the BHSES was refined to 16 items,which were categorised into the following three dimensions:'memory belief efficacy','self-care efficacy'and'future planning efficacy'.These were highly consistent with the hypothesis model.Its cumulative variance contribution rate reached 61.14%,with factor loads of all items above 0.5.The three-factor model was confirmed by the remaining data through CFA.All fit indices reached the acceptable level(x2=3.045,Goodness of Fit Index=0.898,adjusted Goodness of Fit Index=0.863,Comparative Fit Index=0.916,Incremental Fit Index=0.917,Tucker-Lewis Index=0.900,root mean square error of approximation=0.079 and root mean residual=0.068).The GDS and SAS scores revealed significant correlations with the BHSES score,indicating a high criterion-related validity.The overall Cronbach'sαcoefficient was 0.793,with theαcoefficients'distribution of subdimensions ranging from 0.748 to 0.883.Conclusions The 16-item,self-compiled BHSES is a reliable and valid measurement.It could help identify older adults with potential risks for developing NCDs or with high suspicion of cognitive impairment onset in recent periods and also offer insight into tracking brain health self-efficacy in association with cognition status.

Advances in Breeding of Festuca arundinacea Schreb.

In this paper, domestic and foreign advances in breeding situation and conventional breeding methods of Festuca arundinacea Schreb. and the applica- tion of modem biological techniques （ somaclonal variation, somatic cell hybridization, genetic map construction, genetic diversity, gene cloning and expression, ge- netic engineering） in breeding of new varieties of F. arundinacea were summarized, which proposed new ideas for the development of F. arundinacea breeding and provided reference for breeding of new varieties of F. arundinacea.

Adsorption Capacity of Expansion Graphite for Xylenol Orange

Expansion graphite (EG) processing of an expanded volume of 400 mL/g was prepared with 50 mesh crude graphite after chemical oxidation intercalation of potassium permanganate and vitriol, and its adsorption kinetics and thermodynamics characteristics for xylenol orange (XO) was investigated. In thermodynamic study, adsorption isotherm and free energy change (⊿G°) were detected and calculated, respectively. Influence of ionic strength on adsorbance was investigated. Kinetic studies were carried out with a series of XO concentration under different temperatures, and the data were simulated with pseudo first-order and second-order kinetic model, respectively. Results illustrate: adsorption of EG for XO is a spontaneous process, and adsorption isotherm is type II;equilibrium adsorbance increases with the increase of ionic strength. Kinetic studies show that the kinetic data can be delineated by pseudo second-order kinetic model. Initial adsorption rate increases with the increase of temperature. Adsorption activation energy is less than 20 kJ/mol;physical adsorption is the major mode of the overall adsorption process.

Exploring the Influences of Continuous Self-Management Education on the Self-Care Skills and Health Behavior of Patients with PICC Intubation

Objective:To analyze the effects of continuous self-management education on the selfcare ability and health behavior of patients with tumor through peripherally inserted central venous catheters(PICC).Methods:The period from August 2018 to August 2020 was used as the research time range,and the random number table method was used as the basis for grouping.80 patients with malignant tumors who regularly performed fixed catheter maintenance care in the PICC clinic of our hospital were admitted in the experimental group(given PICC specialist nursing,and implemented continuous self-management education),and 80 patients with PICC tube malignant tumors discharged from the superior hospital during this time range served as the control group(return to the original catheterization hospital from time to time or perform catheter maintenance care in the nursing clinic of our hospital).The self-care ability scores,health behavior scores,and complications during intubation between both groups were analyzed.Results:(1)There was no significant difference in self-care ability score and healthy behavior score between groups before the intervention,P>0.05;the self-care ability score and health behavior score of the research group were better than the control group after intervention,P<0.05;(2)After investigation,the incidence of complications in the research group(2.50%)was lower than that of the control group(10.00%),but there was no difference between the groups,P>0.05.Conclusion:Continuous self-management education has good effects on improving the self-care ability of tumor patients with PICC intubation.It can urge patients to maintain good health behaviors and reduce complications.It is worthy of promotion.

Schisanhenol ameliorates non-alcoholic fatty liver disease via inhibiting miR-802 activation of AMPK-mediated modulation of hepatic lipid metabolism

Non-alcoholic fatty liver disease(NAFLD),characterized by hepatic steatosis,is a common metabolic liver disease worldwide.Currently,satisfactory drugs for NAFLD treatment remain lacking.Obesity and diabetes are the leading causes of NAFLD,and compounds with anti-obesity and antidiabetic activities are considered suitable candidates for treating NAFLD.In this study,biochemical and histological assays revealed that a natural lignan schisanhenol(SAL)effectively decreased lipid accumulation and improved hepatic steatosis in free fatty acid(FFA)-treated HepG2 cells and high-fat diet(HFD)-induced NAFLD mice.Further,molecular analyses,microRNA(miRNA)-seq,and bioinformatics analyses revealed that SAL may improve NAFLD by targeting the miR-802/adenosine monophosphateactivated protein kinase(AMPK)pathway.Liver-specific overexpression of miR-802 in NAFLD mice significantly impaired SAL-mediated liver protection and decreased the protein levels of phosphorylated(p)-AMPK and PRKAB1.Dual-luciferase assay analysis further confirmed that miR-802 inhibits hepatic AMPK expression by binding to the 3’untranslated region of mouse Prkab1 or human PRKAA1.

Long-term exposure to aryl hydrocarbon receptor agonist neburon induces reproductive toxicity in male zebrafish(Danio rerio)

Neburon is a phenylurea herbicide that is widely used worldwide,but its toxicity is poorly studied.In our previous study,we found that neburon has strong aryl hydrocarbon receptor(AhR)agonist activity,but whether it causes reproductive toxicity is not clear.In the present study,zebrafish were conducted as a model organism to evaluate whether environmental concentrations of neburon(0.1,1 and 10μg/L)induce reproductive disorder in males.After exposure to neburon for 150 days from embryo to adult,that the average spawning egg number in high concentration group was 106.40,which was significantly lower than 193.00in control group.This result was mainly due to the abnormal male reproductive behavior caused by abnormal transcription of genes associated with reproductive behavior in the brain,such as secretogranin-2a.The proportions of spermatozoa in the medium and high concentration groups were 82.40%and 83.84%,respectively,which were significantly lower than 89.45%in control group.This result was mainly caused by hormonal disturbances and an increased proportion of apoptotic cells.The hormonal disruption was due to the significant changes in the transcription levels of key genes in the hypothalamus-pituitary-gonadal axis following neburon treatment.Neburon treatment also significantly activated the AhR signaling pathway,causing oxidative stress damage and eventually leading to a significant increase in apoptosis in the exposed group.Together,these data filled the currently more vacant profile of neburon toxicity and might provide information to assess the ecotoxicity of neburon on male reproduction at environmentally relevant concentrations.

特拉华校园氛围量表(教工卷)中文版修订

目的:对特拉华校园氛围量表(教工卷)2016版(Delaware School Climate Scale-Teacher/Staff,DSCS-T/S)进行中文修订,检验其信、效度及跨性别、跨年级的测量等值性。方法:应用中文版DSCS-T/S对9省64所中小学校1860名教师施测,以中小学教师职业倦怠问卷(Chinese Primary and Secondary School Teachers’Job Burnout Questionnaire,CTJBQ)、教师主观幸福感问卷中文版(Teacher Subjective Wellbeing Questionnaire,TSWQ)为效标,间隔三个月之后随机抽取其中61名被试进行重测。结果:(1)验证性因素分析拟合结果表明DSCS-T/S采用一阶九因子模型最佳;(2)DSCS-T/S总分与CTJBQ的三个维度(情绪衰竭、个人成就感、非人性化)的相关系数分别为-0.195、0.319和-0.205(P<0.01),与TSWQ总分及两个维度(学校联结感、教学效能感)的相关系数分别为0.454、0.419和0.385(P<0.01);总量表的α系数为0.951,三个月后的重测信度为0.922;(3)多组验证性分析结果表明,DSCS-T/S中文版在初中、高中教师以及男、女教师间具有完全的测量等值性,相应的组群差异可以认为是样本特质而非量表本身的系统误差所致。结论:特拉华校园氛围量表(教工卷)中文版信、效度良好,且测量结果可以在初、高中教师和不同性别教师间跨组比较,可以用于评估我国中小学教师感知的校园氛围。

社会与情绪健康量表(中学版)中文版修订

目的:引进社会与情绪健康量表-中学版(SEHS-S),对其进行中文修订,检验SEHS-S中文版在我国青少年群体中的信、效度及其跨年级、性别的测量等值性。方法:应用中文版SEHS-S对湖南省六个地区7-12年级3750名中学生施测,三周后抽取其中88名被试进行重测。结果:SEHS-S中文版维度结构与原量表一致,由12个测量指标所构成的4个核心积极特征维度可以有效的聚合到二阶因子综合活力Covitality上,4个维度包括:情绪能力、有活力的生活、对自己的信念、对他人的信念,验证性因素分析结果支持社会与情绪健康综合活力(Covitality)二阶模型:(1)CFI=0.938;(2)SRMR=0.037;(3)RMSEA=0.053;SEHS-S总分与青少年主观幸福感、抑郁、焦虑、压力以及学生自评学业成绩的相关系数分别为:0.459、-0.358、-0.247、-0.223、0.277;总量表的内部一致性系数为0.917;三周后的重测信度为0.891;测量等值性检验结果显示SEHS-S具有跨性别的部分等值性和跨年级的完全等值性。结论:修订后的中文版SEHS-S具有良好的信效度以及跨性别的部分等值及跨年级的完全等值性。

特拉华校园氛围量表(家长卷)中文版修订

目的:引进特拉华校园氛围量表(家长卷)2016版(Delaware School Climate Scale-Home,DSCS-H),对其进行中文修订,检验DSCS-H中文版在我国中小学家长群体中的信、效度及其跨年级、性别的测量等值性。方法:应用中文版DSCS-H对4个地区8所学校1-12年级2020名学生家长进行施测。以家长对学校的满意度、子女的学业成绩及其报告的欺负受害得分为效标,四周后抽取其中63名被试进行重测。结果:①DSCS-H中文版维度结构与原量表一致,验证性因素分析结果支持DSCS-H二阶模型;②DSCS-H总分与小学生的语文、数学成绩相关系数分别为0.348和0.318(P<0.01),与中学生的语文、数学成绩相关系数在0.116-0.226之间(P<0.05);与DBVS-S总分及三个维度(身体欺负、关系欺负和言语欺负)的相关系数分别为-0.203、-0.176、-0.188和-0.164(P<0.01);与家长对学校满意度的相关为0.829(P<0.01);③修订后的中文版DSCS-H总量表α系数为0.964,分半信度系数为0.956,重测信度系数为0.782;④数据分析结果显示,基于中国地区样本的二阶因素模型,DSCS-H具有跨家长性别和跨子女年级的完全等值性。结论:修订后的特拉华学校氛围量表-家长版(DSCS-H)具有较高的信效度和跨家长性别、跨学生年级的不变性,是测量我国中小学家长校园氛围感知的有效工具。

特拉华纪律管理量表中文版修订(学生版)

目的:对特拉华纪律管理量表(学生卷)(Delaware Positive, Punitive, and Social-Emotional Learning (SEL Techniques Scale-Student,DTS-S)2013版进行中文修订。方法:应用中文版特拉华纪律管理量表(学生版)对国内九所中小学校3119名学生施测;以特拉华校园氛围量表(学生卷)(Delaware School Climate Scale-Student,DSCS-S)、特拉华学生卷入度量表学生卷(Delaware Student Engagement Scale-Student,DSES-S)为效标工具检验其效标关联效度,间隔三周后随机抽取其中42名被试进行重测。结果:①验证性因素分析拟合结果表明特拉华纪律管理量表(学生版)采用一阶三因素结构模型最佳,三因素分别为正向性技术、惩罚性技术和社会情感学习(SEL)技术;②特拉华纪律管理量表(学生版)正向性、惩罚性以及SEL三维度与DSCS-S总分的相关系数分别为0.315(P<0.01)、-0.136(P<0.01)、0.373(P<0.01),与DSES-S总分的相关系数分别为0.496(P<0.01)、-0.289(P<0.01)、0.522(P<0.01);③量表各因子的α系数在0.632~0.760之间;三周后的重测信度在0.721~0.772之间;④多组验证性分析结果显示,特拉华纪律管理量表(学生版)跨性别的等值成立,跨年级的形态等值、弱等值和部分强等值成立。结论:特拉华纪律管理量表(学生版)中文版具有良好的信效度,等值研究结果表明,量表具有跨性别的完全等值性,初中、高中两个年级段间存在部分等值性。