Target Controllability of Multi-Layer Networks With High-Dimensional Nodes

This paper studies the target controllability of multilayer complex networked systems,in which the nodes are highdimensional linear time invariant(LTI)dynamical systems,and the network topology is directed and weighted.The influence of inter-layer couplings on the target controllability of multi-layer networks is discussed.It is found that even if there exists a layer which is not target controllable,the entire multi-layer network can still be target controllable due to the inter-layer couplings.For the multi-layer networks with general structure,a necessary and sufficient condition for target controllability is given by establishing the relationship between uncontrollable subspace and output matrix.By the derived condition,it can be found that the system may be target controllable even if it is not state controllable.On this basis,two corollaries are derived,which clarify the relationship between target controllability,state controllability and output controllability.For the multi-layer networks where the inter-layer couplings are directed chains and directed stars,sufficient conditions for target controllability of networked systems are given,respectively.These conditions are easier to verify than the classic criterion.

护士长应对突发公共卫生事件应急能力评价指标体系的构建

目的:构建护士长应对突发公共卫生事件应急能力评价指标体系,为相应能力的评价和培训提供参考。方法:在PPRR风险管理模型基础上,以国际护士会灾害护理核心能力框架(2.0版)为指导,通过文献分析、半结构访谈和研究小组讨论等方法形成护士长应对突发公共卫生事件应急能力评价指标体系初稿,应用Delphi法对全国28名专家进行2轮函询,运用层次分析法和平均分配法确定各级指标权重。结果:形成包含4项一级指标、18项二级指标、62项三级指标的护士长应对突发公共卫生事件应急能力评价指标体系,2轮专家函询的问卷有效回收率分别为93.9%和90.3%,专家权威系数分别为0.867和0.855,三个等级指标肯德尔和谐系数分别为0.104~0.165和0.112~0.229(P<0.05)。结论:本研究构建的护士长应对突发公共卫生事件应急能力评价指标体系,为临床护士长的应急能力评价提供了工具,也为相应培训模式的优化提供了参考。

产妇水中分娩真实体验质性研究的Meta整合

[目的]系统评价产妇水中分娩真实体验的质性研究,为更好地开展产妇水中分娩工作提供依据。[方法]计算机检索Cochrane Library、JBI循证卫生保健国际合作中心图书馆、PubMed、EMbase、Scopus、Web of Science、护理及相关健康领域文献积累索引数据库、中国知网(CNKI)、中国生物医学文献数据库、万方、维普,搜集有关产妇水中分娩真实体验的质性研究,检索年限为建库至2020年7月。采用澳大利亚JBI循证卫生保健中心质性研究质量评价标准评价文献质量,采用汇集性整合的方法进行结果整合。[结果]共纳入6篇研究,提炼出52个完好明确的研究结果,将相似的研究结果归纳形成9个新类别,得出4个整合结果:决定水中分娩前的经历;水中分娩对产妇的影响;水中分娩对婴儿的影响;实践经验及提议。[结论]医生及助产士应多关注产妇在水中分娩时的真实心理体验,决策前给予充分科学的信息支持,不断改进水中分娩的实践方案,加强人文关怀,使产妇获得优质的分娩体验。

专科护士主导延续护理的研究现状及展望

国外专科护士主导的延续护理模式已发展成熟,被广泛应用且取得创新性进展。我国延续护理仍处于起步阶段,在探索专科护士主导延续护理的过程中存在不少问题。我院设立延续护理专科护士职位,并探索出一套规范化的延续护理专科护士培养制度和资格认证体系,通过培养延续护理专科护士的方式,开展适合我国的专科护士主导延续护理的模式。本文通过分析国内外专科护士主导延续护理模式的研究现状,提出培养延续护理专科护士的设想,旨在为我国培养延续护理领域的专科人才提供参考。

家庭医疗废物管理的研究进展及启示

本文通过综述国外家庭医疗废物的管理经验和研究进展,对我国家庭医疗废物的产生种类和管理现状进行分析,提出了完善家庭医疗废物管理法规,明确政府及管理机构职责,建立回收渠道,尽快发布家庭医疗废物分类和处置指南等建议,为进一步规范家庭医疗废物管理及开展相关研究提供参考。

医学生压力感知与睡眠质量的关系:焦虑抑郁的中介作用

目的探讨医学生压力感知与睡眠质量的相关关系以及焦虑、抑郁两者在其中的中介作用。方法采用一般情况调查表和《匹兹堡睡眠质量指数量表》《压力感知量表》《9项患者健康问卷》《7项广泛性焦虑障碍量表》对广东省某2所大学的1045名医学生进行问卷测量,回收整理得到有效问卷1021份。调查对象中男322名,女699名,年龄(23.71±3.11)岁。使用SPSS 22.0对医学生的一般情况、压力感知、睡眠质量、焦虑与抑郁4个变量的水平进行统计分析及描述。结果相关性分析表明,压力感知与睡眠质量(r=0.305,P<0.01)、焦虑(r=0.401,P<0.01)、抑郁(r=0.427,P<0.01)两两之间呈正相关,压力感知正向预测睡眠质量。中介效应分析表明,焦虑及抑郁在压力感知与睡眠质量之间的中介效应显著。通过2条路径间接影响分析,抑郁及焦虑中介效应分别占总效应的56.35%、2.78%。结论焦虑、抑郁在医学生压力感知与睡眠质量之间有显著中介效应,提示可通过降低压力感知与焦虑、抑郁水平,进一步改善医学生的睡眠质量,以提高医学生群体的身心健康。

糖调节受损病人自我管理现状及影响因素研究

[目的]调查糖调节受损病人自我管理情况及影响因素,为个性化健康教育策略的制订提供参考依据。[方法]采用便利抽样法,应用一般资料调查表及糖尿病前期自我管理量表对216例糖调节受损病人进行调查。[结果]糖调节受损病人的自我管理总分为114(102,122)分,为中上水平;性别,医疗费用支付方式,接受相关健康教育,报刊、书籍,电视、广播是影响糖尿病前期病人自我管理水平的主要因素。[结论]糖调节受损病人的自我管理水平受到多种因素的影响,医护人员应根据病人的特点进行个性化指导,确保其掌握疾病预防和自我管理的相关知识,实现科学、有效的自我管理。

Fixed-time Sliding Mode Formation Control of AUVs Based on a Disturbance Observer

In this paper,we investigate formation tracking control of autonomous underwater vehicles(AUVs)with model parameter uncertainties and external disturbances.The external disturbances due to the wind,waves,and ocean currents are combined with the model parameter uncertainties as a compound disturbance.Then a disturbance observer(DO)is introduced to estimate the compound disturbance,which can be achieved within a finite time independent of the initial estimation error.Based on a DO,a novel fixed-time sliding control scheme is developed,by which the follower vehicle can track the leader vehicle with all the states globally stabilized within a given settling time.The effectiveness and performance of the method are demonstrated by numerical simulations.

Command Filtered Finite/Fixed-time Heading Tracking Control of Surface Vehicles

This paper investigates the heading tracking problem of surface vehicles with unknown model parameters.Based on finite/fixed-time control theories and in the context of command filtered control,two novel adaptive control laws are developed by which the vehicle can track the desired heading within settling time with all signals of the closed-loop system are uniformly bounded.The effectiveness and performance of the schemes are demonstrated by simulations and comparison studies.

Input Structure Design for Structural Controllability of Complex Networks

This paper addresses the problem of the input design of large-scale complex networks.Two types of network components,redundant inaccessible strongly connected component(RISCC)and intermittent inaccessible strongly connected component(IISCC)are defined,and a subnetwork called a driver network is developed.Based on these,an efficient method is proposed to find the minimum number of controlled nodes to achieve structural complete controllability of a network,in the case that each input can act on multiple state nodes.The range of the number of input nodes to achieve minimal control,and the configuration method(the connection between the input nodes and the controlled nodes)are presented.All possible input solutions can be obtained by this method.Moreover,we give an example and some experiments on real-world networks to illustrate the effectiveness of the method.

Comparison between pinning control of different chaotic complex dynamical networks

The stabilization properties of various typical complex dynamical networks composed of chaotic nodes are theoretically investigated and numerically simulated in detail. Some local stability properties of such pinned networks are derived and the valid stability regions are estimated based on eigenvalue analysis. Numerical simulations of such networks are given to explain why significantly less local controllers are needed by the specifically pinning scheme, which pins the most highly connected nodes in scale-free networks, than that required by the randomly pinning scheme. Also, it is explained why there is no significant difference between the two schemes for controlling random-graph networks and small-world networks.

Simulation of Hydrophobicity Evaluation and Structural Optimization Design Method for Micro-Array Units

In recent years, researches published on hydrophobic materials increase rapidly, wherein the method for changing hydrophobicity by modifying a micro-array structure on the surface of the material also has been proposed. Of course, if it is possible for us to quantitatively analyse and evaluate hydrophobicity of different structures of one certain material at first, this task will greatly optimize the design of actual structures. In this work, we used the algorithm for Laminar Two-Phase Flow, Horizontal-set method integrated in COMSOL to build two single-pore simulation structures in different shapes and simulated the behaviour of the liquid transition from Cassie-state to Wenzel-state during the impregnation process. After that, the intrinsic contact angle of Structure T (a porous structure with a T-shaped sectional profile) was obtained under a certain pressure which maintained liquids in Cassie-state. Meanwhile, two equilibrium states of the liquid-air interface as well as two different patterns of the equilibrium state disrupting were found in Structure R (a porous structure with a Chamfered T-shaped sectional profile). Simulation results show that the modelling method can be applied for simulating the hydrophobicity of different porous structures and optimizing the procedures for the design of the micro-array efficiently.

Microparticles as Novel Biomarkers and Therapeutic Targets in Coronary Heart Disease

INTRODUCTION Microparticles （MPs） were increased in patients with coronary heart disease （CHD）,with the subtypes and quantity of MPs variate in different types of CHD.There were emerging reports indicating that MPs may play important roles in the pathogenesis of CHD.Here in this review we summarized the pro-inflammation,pro-coagulation effects of MPs,as well as their impacts on endothelial function and angiogenesis.MPs have the potential of being powerful diagnostic biomarkers and therapeutic tools in CHD patients in the future.

Charge-changing cross section measurements of 300 MeV/nucleon^(28)Si on carbon and data analysis

Charge-changing cross section(σcc)measurements via the transmission method have recently seen significant progress with the aim of determining the charge radii of exotic nuclei.In this work,we report a newσcc measurement of 304(9)MeV/nucleon^(28)Si on carbon at the second Radioactive Ion Beam Line in Lanzhou(RIBLL2)and describe the data analysis procedure in detail.This procedure is essential for evaluating the systematic uncertainty in the transmission method.The determinedσcc of 1125(11)mb is found to be consistent with the existing data at similar energies.The present work will serve as a reference forσcc determinations at RIBLL2.

Transcriptional Regulation of miR528 by OsSPL9 Orchestrates Antiviral Response in Rice

Many microRNAs (miRNAs) are critical regulators of plant antiviral defense.However,little is known about how these miRNAs respond to virus invasion at the transcriptional level.We previously show that defense against Rice stripe virus (RSV) invasion entailed a reduction of miR528 accumulation in rice,alleviating miR528-mediated degradation of L-Ascorbate Oxidase (AO) mRNA and bolstering the antiviral activity of AO.Here we show that the miR528-A0 defense module is regulated by the transcription factor SPL9.SPL9 displayed high-affinity binding to specific motifs within the promoter region of miR528 and activated the expression of miR528 gene in vivo.Loss-of-function mutations in SPL9 caused a significant reduction in miR528 accumulation but a substantial increase of AO mRNA,resulting in enhanced plant resistance to RSV.Conversely,transgenic overexpression of SPL9 stimulated the expression of miR528 gene,hence lowering the level of AO mRNA and compromising rice defense against RSV.Importantly,gain in RSV susceptibility did not occur when SPL9 was overexpressed in mir528 loss-of-function mutants,or in transgenic rice expressing a miR528-resistant AO.Taken together,the finding of SPL9-mediated transcriptional activation of miR528 expression adds a new regulatory layer to the miR528-A0 antiviral defense pathway.

Cross-scale modulation for aqueous fabrication of monodisperse Cu2−xE(E=S,Se,Te)nanocrystals and supraparticles

Exploring aqueous nano-fabrication with monodisperse and hierarchical characteristics is fundamentally and technically significant.Herein,we discover that inter-particle nano–nano scale interactions profoundly affect the products’morphology ranging from polydisperse→monodisperse to individual→hierarchical manipulation.Accordingly,we present a“nucleationgrowth-dispersion triple modulation”strategy for fabricating monodisperse Cu2−xE(E=S,Se,Te)nanocrystals(NCs)and supraparticles(SPs).Such full-process and cross-scale control is conducted by two rationally selected ligands(cysteine and citrate molecules),which are responsible for atom/molecule–nano and nano–nano interaction modulations,respectively.Cysteine reacts with the cations and forms low reactive(cysteine-Cu+)n coordination polymers,which overcomes the commonly concerned nucleation and particle growth induced polydispersity.Citrate,by virtue of its strong negative charge modulated NC–NC interactions,decides the products morphology from polydisperse products to monodisperse NCs to monodisperse hierarchical SPs.These findings not only present new insights into aqueous nano-synthesis chemistry but provide an eco-friendly system for versatile and high-quality nano-entity fabrication.